{"artifact":{"id":"paper-fig-37245027-5","artifact_type":"paper_figure","entity_ids":"[]","title":"Fig. 5: Appearance of leukocytes in CNS during PA-induced lung infection.  a  White bloo...","quality_score":0.95,"created_by":"paper_figures_pipeline","provenance_chain":"[{\"source\": \"paper\", \"paper_id\": \"37245027\", \"relation\": \"extracted_from\"}]","content_hash":"5ba41b23beec04c0a9e359a17c9b8ca1a75c97bd8103c63d9ff0c7f983421a35","metadata":{"doi":"","pmcid":"PMC10223932","_origin":{"url":"https://www.ebi.ac.uk/europepmc/articles/PMC10223932/bin/12974_2023_2817_Fig5_HTML.jpg","type":"external","tracked_at":"2026-04-16T11:31:39.705527"},"caption":"Appearance of leukocytes in CNS during PA-induced lung infection.  a  White blood counts in control and PA-infected animals (OD 600  0.3). Mann–Whitney test, P = 0.016 vs. control (uninfected) group.  b  Neutrophil and monocyte counts in blood obtained from control and PA-infected mice (OD 600  0.3) measured by ProCyte One hematology analyzer. Mann–Whitney test, P = 0.04, P = 0.03 vs. control (uninfected) group.  c  Flow cytometry analysis of brain tissue homogenates labeled with anti-CD45 and anti-CD11b antibodies with gating on CD45 +  cells. Quantitative analyses of ( d ) infiltrated leukocytes and ( e ) microglia in control and PA infected mice. Mann–Whitney test, P = 0.03 vs. control (uninfected) group. In all graphs, each point indicates data from an individual animal, bar graphs (columns and error bars) show mean ± S.E.M.  f  Representative confocal images of infiltrated leukocytes (CD45 + ; green) in the brain from a control (left) and a PA-lung infected mouse (right). DAPI (nu","paper_id":"37245027","image_url":"https://www.ebi.ac.uk/europepmc/articles/PMC10223932/bin/12974_2023_2817_Fig5_HTML.jpg","image_path":"","description":"","figure_label":"Fig. 5","figure_number":5,"_schema_version":1,"source_strategy":"pmc_api","entities_mentioned":""},"created_at":"2026-04-16T11:31:39-07:00","updated_at":"2026-04-16T21:02:10.792794-07:00","version_number":4,"parent_version_id":null,"version_tag":null,"changelog":null,"is_latest":1,"lifecycle_state":"active","superseded_by":null,"deprecated_at":null,"deprecated_reason":null,"dependencies":null,"market_price":0.5,"origin_type":"external","origin_url":"https://www.ebi.ac.uk/europepmc/articles/PMC10223932/bin/12974_2023_2817_Fig5_HTML.jpg","lifecycle_changed_at":"2026-04-16T11:31:39-07:00","citation_count":0,"embed_count":0,"derivation_count":0,"support_count":0,"contradiction_count":0,"total_usage":0.0,"usage_score":0.5,"usage_computed_at":null,"quality_status":"ok","contributors":[],"answers_question_ids":null,"deprecated_reason_detail":null,"deprecated_reason_code":null,"commit_sha":null,"commit_submodule":null,"last_mutated_at":"2026-05-16T14:51:34.657673-07:00","disputed_at":null,"gap_id":null,"mission_id":null,"intrinsic_priority":null,"effective_priority":null,"artifact_id":"76917a05-844d-44a6-b13f-ad0317921ba0","artifact_dir":null,"primary_filename":null,"accessory_filenames":null,"folder_layout_version":1,"migrated_to_folder_at":null,"hypothesis_id":null,"authorship":{"kind":"human","contributors":[{"role":"author","actor_ref":"paper_figures_pipeline"}]},"epistemic_tier":"T3_provisional","created_by_agent_id":null},"outgoing_links":[{"target_artifact_id":"paper-37245027","link_type":"derives_from","strength":1.0,"evidence":"paper_figure metadata/provenance references PMID 37245027"}],"incoming_links":[],"current_artifact_id":"paper-fig-37245027-5","is_canonical":true,"supersede_chain":["paper-fig-37245027-5"]}