{"artifact":{"id":"paper-fig-39364217-2","artifact_type":"paper_figure","entity_ids":"[]","title":"Figure 2: Overview of characteristic features of senescent microglia: expression of senesc...","quality_score":0.5,"created_by":"paper_figures_pipeline","provenance_chain":"[{\"source\": \"paper\", \"paper_id\": \"39364217\", \"relation\": \"extracted_from\"}]","content_hash":"8b0c443a33aea09cc6db6bbdaffd7d90061e81805dd88bf865d6c1606116c8d2","metadata":{"doi":"","pmcid":"PMC11449118","_origin":{"url":"https://www.ebi.ac.uk/europepmc/articles/PMC11449118/bin/NEP3-2-182-g001.jpg","type":"external","tracked_at":"2026-04-26T06:44:08.591845"},"caption":"Overview of characteristic features of senescent microglia: expression of senescence‐associated secretory phenotype, morphological deramification, mitotic arrest (loss of proliferative capacity), intracellular iron overload, and increased cell body hypertrophy. Cellular senescence markers, such as senescence‐associated β‐galactosidase (SA‐β‐gal) activity, and lipofuscin accumulation, are also depicted. IL, interleukin; SASP, senescence‐associated secretory phenotype; TNF, tumor necrosis factor.","paper_id":"39364217","image_url":"https://www.ebi.ac.uk/europepmc/articles/PMC11449118/bin/NEP3-2-182-g001.jpg","image_path":"","description":"","figure_label":"Figure 2","figure_number":2,"_schema_version":1,"source_strategy":"pmc_api","entities_mentioned":""},"created_at":"2026-04-25T23:44:08.591987-07:00","updated_at":"2026-04-25T23:44:08.591987-07:00","version_number":4,"parent_version_id":null,"version_tag":null,"changelog":null,"is_latest":1,"lifecycle_state":"active","superseded_by":null,"deprecated_at":null,"deprecated_reason":null,"dependencies":null,"market_price":0.5,"origin_type":"external","origin_url":"https://www.ebi.ac.uk/europepmc/articles/PMC11449118/bin/NEP3-2-182-g001.jpg","lifecycle_changed_at":"2026-04-25T23:44:08.591987-07:00","citation_count":0,"embed_count":0,"derivation_count":0,"support_count":0,"contradiction_count":0,"total_usage":0.0,"usage_score":0.5,"usage_computed_at":null,"quality_status":null,"contributors":[],"answers_question_ids":null,"deprecated_reason_detail":null,"deprecated_reason_code":null,"commit_sha":null,"commit_submodule":null,"last_mutated_at":"2026-05-16T14:51:34.657673-07:00","disputed_at":null,"gap_id":null,"mission_id":null,"intrinsic_priority":null,"effective_priority":null,"artifact_id":"db9e51c3-3d12-4ea8-97ad-28239ac2d049","artifact_dir":null,"primary_filename":null,"accessory_filenames":null,"folder_layout_version":1,"migrated_to_folder_at":null,"hypothesis_id":null,"authorship":{"kind":"human","contributors":[{"role":"author","actor_ref":"paper_figures_pipeline"}]},"epistemic_tier":"T3_provisional","created_by_agent_id":null},"outgoing_links":[],"incoming_links":[],"current_artifact_id":"paper-fig-39364217-2","is_canonical":true,"supersede_chain":["paper-fig-39364217-2"]}