{"artifact":{"id":"paper-fig-a1839c20-fe07-4055-8249-992df59d2940-5","artifact_type":"paper_figure","entity_ids":"[]","title":"Figure 5: Age acceleration in Alzheimer's disease and schizophrenia. All plots show result...","quality_score":0.5,"created_by":"paper_figures_pipeline","provenance_chain":"[{\"source\": \"paper\", \"paper_id\": \"a1839c20-fe07-4055-8249-992df59d2940\", \"relation\": \"extracted_from\"}]","content_hash":"81e711e7ee536d7df56742a9bcfea9d3209bf81ad2d90a02e2b98abb99eff717","metadata":{"doi":"10.1002/advs.202506109","pmcid":"PMC12631854","_origin":{"url":"https://www.ebi.ac.uk/europepmc/articles/PMC12631854/bin/ADVS-12-e06109-g001.jpg","type":"external","tracked_at":"2026-04-22T23:25:46.269338"},"caption":"Age acceleration in Alzheimer's disease and schizophrenia. All plots show results from the application of bootstrapped‐pseudobulk cell‐type‐specific aging clocks in each of the major cell types in snRNA‐seq data of post mortem prefrontal cortex tissue from Fröhlich et al. [ \n \n 18 \n \n ]  and Gabitto et al. [ \n \n 46 \n \n ]  a) Left‐Relationship between chronological age and predicted age in schizophrenia (red) and control samples (grey). The line was computed with seaborn.regplot function represents the regression line fitted to the points of the given condition. Right‐Box plots showing the age acceleration in control samples (grey) and schizophrenia (red). b) Left‐Relationship between chronological age and predicted age in High‐AD (red) and control samples (grey). The line was computed with seaborn.regplot function represents the regression line fitted to the points of the given condition. Right‐Box plots showing the age acceleration in control samples (grey) and High‐AD samples (red). ","paper_id":"a1839c20-fe07-4055-8249-992df59d2940","image_url":"https://www.ebi.ac.uk/europepmc/articles/PMC12631854/bin/ADVS-12-e06109-g001.jpg","image_path":"","description":"","figure_label":"Figure 5","figure_number":5,"_schema_version":1,"source_strategy":"pmc_api","entities_mentioned":""},"created_at":"2026-04-22T16:25:46.269464-07:00","updated_at":"2026-04-22T16:25:46.269464-07:00","version_number":4,"parent_version_id":null,"version_tag":null,"changelog":null,"is_latest":1,"lifecycle_state":"active","superseded_by":null,"deprecated_at":null,"deprecated_reason":null,"dependencies":null,"market_price":0.5,"origin_type":"external","origin_url":"https://www.ebi.ac.uk/europepmc/articles/PMC12631854/bin/ADVS-12-e06109-g001.jpg","lifecycle_changed_at":"2026-04-22T16:25:46.269464-07:00","citation_count":0,"embed_count":0,"derivation_count":0,"support_count":0,"contradiction_count":0,"total_usage":0.0,"usage_score":0.5,"usage_computed_at":null,"quality_status":null,"contributors":[],"answers_question_ids":null,"deprecated_reason_detail":null,"deprecated_reason_code":null,"commit_sha":null,"commit_submodule":null,"last_mutated_at":"2026-05-16T14:51:34.657673-07:00","disputed_at":null,"gap_id":null,"mission_id":null,"intrinsic_priority":null,"effective_priority":null,"artifact_id":"138a1ee3-40ff-46a5-9030-33b7e7968578","artifact_dir":null,"primary_filename":null,"accessory_filenames":null,"folder_layout_version":1,"migrated_to_folder_at":null,"hypothesis_id":null,"authorship":{"kind":"human","contributors":[{"role":"author","actor_ref":"paper_figures_pipeline"}]},"epistemic_tier":"T3_provisional","created_by_agent_id":null},"outgoing_links":[],"incoming_links":[],"current_artifact_id":"paper-fig-a1839c20-fe07-4055-8249-992df59d2940-5","is_canonical":true,"supersede_chain":["paper-fig-a1839c20-fe07-4055-8249-992df59d2940-5"]}