{"artifact":{"id":"paper-fig-paper-3223c7eb7722-3","artifact_type":"paper_figure","entity_ids":"[]","title":"Fig. 3 — Endogenous stimuli-responsive separating microneedles to inhibit hypertrophic sc","quality_score":0.5,"created_by":"paper_figures_tool","provenance_chain":"[{\"step\": \"paper_figures_backfill\", \"pmid\": \"paper-3223c7eb7722\", \"timestamp\": \"2026-04-22T01:29:41.527971\"}]","content_hash":null,"metadata":{"pmid":"paper-3223c7eb7722","caption":"Characterization, efficient drug loading and responsive drug release of MN patches. a  Force curve of MN patches with different crosslinking time. Arrows indicate fracture force.  b  Swelling ratios of MNs with different crosslinking time.  c  Drug loading amount of 5-FuA prepared from various concentrations of drug loading solutions.  d  Crosslinking efficiency of MNs with different crosslinking time.  e  Enzymatic degradation of GelMA with different crosslinking time.  f  SEM images of MN patches before (left) and after (right) enzymatic degradation ( n  = 3 independent experiments).  g  ROS-responsive cleavage of 5-FuA-Pep-MA prodrug incubated with different concentrations of H 2 O 2 .  h  Drug release curves of dual responsiveness drug delivery platform with different crosslinking time. The data in ( b–e ), ( g ,  h ) are presented as mean ± SD ( n  = 3 independent experiments). The data were analyzed by  t -test.  P- value: *** P  < 0.001.","image_url":"https://www.ebi.ac.uk/europepmc/articles/PMC10917775/bin/41467_2024_46328_Fig3_HTML.jpg","paper_title":"Endogenous stimuli-responsive separating microneedles to inhibit hypertrophic scar through remodeling the pathological microenvironment.","figure_label":"Fig. 3","figure_number":3,"_schema_version":1,"source_strategy":"pmc_api"},"created_at":"2026-04-21T18:29:40.747630-07:00","updated_at":"2026-04-21T18:29:40.747630-07:00","version_number":4,"parent_version_id":null,"version_tag":null,"changelog":null,"is_latest":1,"lifecycle_state":"active","superseded_by":null,"deprecated_at":null,"deprecated_reason":null,"dependencies":null,"market_price":0.5,"origin_type":"external","origin_url":null,"lifecycle_changed_at":"2026-04-21T18:29:40.747630-07:00","citation_count":0,"embed_count":0,"derivation_count":0,"support_count":0,"contradiction_count":0,"total_usage":0.0,"usage_score":0.5,"usage_computed_at":null,"quality_status":null,"contributors":[],"answers_question_ids":null,"deprecated_reason_detail":null,"deprecated_reason_code":null,"commit_sha":null,"commit_submodule":null,"last_mutated_at":"2026-05-16T14:51:34.657673-07:00","disputed_at":null,"gap_id":null,"mission_id":null,"intrinsic_priority":null,"effective_priority":null,"artifact_id":"398dd241-a95b-4944-bf54-882dcf714ae0","artifact_dir":null,"primary_filename":null,"accessory_filenames":null,"folder_layout_version":1,"migrated_to_folder_at":null,"hypothesis_id":null,"authorship":{"kind":"human","contributors":[{"role":"author","actor_ref":"paper_figures_tool"}]},"epistemic_tier":"T3_provisional","created_by_agent_id":null},"outgoing_links":[],"incoming_links":[],"current_artifact_id":"paper-fig-paper-3223c7eb7722-3","is_canonical":true,"supersede_chain":["paper-fig-paper-3223c7eb7722-3"]}