{"artifact":{"id":"paper-fig-paper-eec8991d7498-2","artifact_type":"paper_figure","entity_ids":"[]","title":"Fig. 1 — TREM2hi resident macrophages protect the septic heart by maintaining cardiomyocy","quality_score":0.5,"created_by":"paper_figures_tool","provenance_chain":"[{\"step\": \"paper_figures_backfill\", \"pmid\": \"paper-eec8991d7498\", \"timestamp\": \"2026-04-22T01:29:41.771572\"}]","content_hash":null,"metadata":{"pmid":"paper-eec8991d7498","caption":"Single-cell atlas of cardiac immune cells during sepsis progression. a , Schematic diagram showing scRNA-seq pipeline of murine cardiac immune cells during sepsis progression. SS, steady state.  b , Uniform Manifold Approximation and Projection (UMAP) plots of 29,537 cardiac immune cells allocated into 15 clusters from the hearts of 14 WT mice at SS, 3, 7 and 21 d after CLP. Cardiac cells from 3–4 mice were mixed as one sample.  c , UMAP plots of cardiac immune cells colored by cell type.  d , Heat map showing selected cluster marker genes (top, color-coded by cluster and condition) with exemplar genes and cell-type annotation labeled.  e , UMAP plots of cardiac immune cells from WT mice in different time points of sepsis, annotated by cell type as in  c . Each time point is contributed by either three (SS or 21 d) or four mice (3 or 7 d).  f , Bar plots showing the distribution of immune cell types from WT mice at different time points of sepsis (Extended Data Figs.  1  and  2 ). Sour","image_url":"https://www.ebi.ac.uk/europepmc/articles/PMC9886554/bin/42255_2022_715_Fig1_HTML.jpg","paper_title":"TREM2hi resident macrophages protect the septic heart by maintaining cardiomyocyte homeostasis.","figure_label":"Fig. 1","figure_number":2,"_schema_version":1,"source_strategy":"pmc_api"},"created_at":"2026-04-21T18:29:40.747630-07:00","updated_at":"2026-04-21T18:29:40.747630-07:00","version_number":4,"parent_version_id":null,"version_tag":null,"changelog":null,"is_latest":1,"lifecycle_state":"active","superseded_by":null,"deprecated_at":null,"deprecated_reason":null,"dependencies":null,"market_price":0.5,"origin_type":"external","origin_url":null,"lifecycle_changed_at":"2026-04-21T18:29:40.747630-07:00","citation_count":0,"embed_count":0,"derivation_count":0,"support_count":0,"contradiction_count":0,"total_usage":0.0,"usage_score":0.5,"usage_computed_at":null,"quality_status":null,"contributors":[],"answers_question_ids":null,"deprecated_reason_detail":null,"deprecated_reason_code":null,"commit_sha":null,"commit_submodule":null,"last_mutated_at":"2026-05-16T14:51:34.657673-07:00","disputed_at":null,"gap_id":null,"mission_id":null,"intrinsic_priority":null,"effective_priority":null,"artifact_id":"97f3a01f-1a7c-4587-b15b-ac45b97f669d","artifact_dir":null,"primary_filename":null,"accessory_filenames":null,"folder_layout_version":1,"migrated_to_folder_at":null,"hypothesis_id":null,"authorship":{"kind":"human","contributors":[{"role":"author","actor_ref":"paper_figures_tool"}]},"epistemic_tier":"T3_provisional","created_by_agent_id":null},"outgoing_links":[],"incoming_links":[],"current_artifact_id":"paper-fig-paper-eec8991d7498-2","is_canonical":true,"supersede_chain":["paper-fig-paper-eec8991d7498-2"]}