{"artifact":{"id":"paper-fig-paper-ffa45a0b8e6b-2","artifact_type":"paper_figure","entity_ids":"[]","title":"Figure 2 — Chemerin/ChemR23 axis promotes inflammation of glomerular endothelial cells in d","quality_score":0.5,"created_by":"paper_figures_tool","provenance_chain":"[{\"step\": \"paper_figures_backfill\", \"pmid\": \"paper-ffa45a0b8e6b\", \"timestamp\": \"2026-04-22T01:29:42.681122\"}]","content_hash":null,"metadata":{"pmid":"paper-ffa45a0b8e6b","caption":"LV3‐shRNA was used to knock down ChemR23 of db/db mice. A, Immunofluorescence staining of GFP in the control or shRNA group to show the transfection efficiency. B‐E, At the end of the study, body weight, blood glucose, serum creatinine and urine albumin to creatinine ratio of mice were measured and compared among groups (n = 8). F, Representative IHC staining of chemerin and ChemR23 in each group. Green arrow shows the cytoplasmic or membrane expression. G, Western blot showed expression levels of chemerin, ChemR23 and CD31 in each group. GAPDH was used as an internal control. * P  < 0.05 vs control, # P  < 0.05 vs DN","image_url":"https://www.ebi.ac.uk/europepmc/articles/PMC6484295/bin/JCMM-23-3417-g002.jpg","paper_title":"Chemerin/ChemR23 axis promotes inflammation of glomerular endothelial cells in diabetic nephropathy.","figure_label":"Figure 2","figure_number":2,"_schema_version":1,"source_strategy":"pmc_api"},"created_at":"2026-04-21T18:29:40.747630-07:00","updated_at":"2026-04-21T18:29:40.747630-07:00","version_number":4,"parent_version_id":null,"version_tag":null,"changelog":null,"is_latest":1,"lifecycle_state":"active","superseded_by":null,"deprecated_at":null,"deprecated_reason":null,"dependencies":null,"market_price":0.5,"origin_type":"external","origin_url":null,"lifecycle_changed_at":"2026-04-21T18:29:40.747630-07:00","citation_count":0,"embed_count":0,"derivation_count":0,"support_count":0,"contradiction_count":0,"total_usage":0.0,"usage_score":0.5,"usage_computed_at":null,"quality_status":null,"contributors":[],"answers_question_ids":null,"deprecated_reason_detail":null,"deprecated_reason_code":null,"commit_sha":null,"commit_submodule":null,"last_mutated_at":"2026-05-16T14:51:34.657673-07:00","disputed_at":null,"gap_id":null,"mission_id":null,"intrinsic_priority":null,"effective_priority":null,"artifact_id":"87d56feb-3121-4e4c-8c81-b75f9653cac0","artifact_dir":null,"primary_filename":null,"accessory_filenames":null,"folder_layout_version":1,"migrated_to_folder_at":null,"hypothesis_id":null,"authorship":{"kind":"human","contributors":[{"role":"author","actor_ref":"paper_figures_tool"}]},"epistemic_tier":"T3_provisional","created_by_agent_id":null},"outgoing_links":[],"incoming_links":[],"current_artifact_id":"paper-fig-paper-ffa45a0b8e6b-2","is_canonical":true,"supersede_chain":["paper-fig-paper-ffa45a0b8e6b-2"]}