{"artifact":{"id":"paper-figure-40281419-4","artifact_type":"paper_figure","entity_ids":null,"title":"Figure 4 from PMID:40281419","quality_score":0.95,"created_by":null,"provenance_chain":null,"content_hash":null,"metadata":{"pmid":"40281419","pmc_id":"PMC12032786","caption":"FOXP2 and CASK protein signals co-localize within striatal and cerebellar neurons. A Nissl stain of sagittal section of the male zebra finch brain at the level of the cerebellum and Area X (dotted white circle). B Nissl stain of the zebra finch telencephalon at the level of striatal Area X (dotted white circle) which is visible bilaterally. C–F Photomicrographs show immunostain signals for DNA (DAPI-blue), FOXP2 (green) and CASK (red) as well as a merged image (far right panel in each row). C As expected, cerebellar Purkinje neurons do not show strong DAPI signals (left panel; white arrowheads) but do co-stain for FOXP2 and CASK. D Striatal neurons from an adult male zebra finch housed with a female (mixed singer; see Methods) show co-localization of FOXP2 and CASK signals (white arrowheads). In striking contrast, those from a male who sang alone (E) show undetectable FOXP2 signals and strong CASK signals whereas those from a non-singer (F) show robust FOXP2 signals and undetectable CA","image_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12032786/figure/Fig4/","figure_label":"Figure 4","figure_number":4,"_schema_version":1},"created_at":"2026-04-13T06:15:55-07:00","updated_at":"2026-04-16T21:10:08.528104-07:00","version_number":4,"parent_version_id":null,"version_tag":null,"changelog":null,"is_latest":1,"lifecycle_state":"active","superseded_by":null,"deprecated_at":null,"deprecated_reason":null,"dependencies":null,"market_price":0.5,"origin_type":"internal","origin_url":null,"lifecycle_changed_at":"2026-04-13T06:15:55-07:00","citation_count":0,"embed_count":0,"derivation_count":0,"support_count":0,"contradiction_count":0,"total_usage":0.0,"usage_score":0.5,"usage_computed_at":null,"quality_status":"ok","contributors":[],"answers_question_ids":null,"deprecated_reason_detail":null,"deprecated_reason_code":null,"commit_sha":null,"commit_submodule":null,"last_mutated_at":"2026-05-16T14:51:34.657673-07:00","disputed_at":null,"gap_id":null,"mission_id":null,"intrinsic_priority":null,"effective_priority":null,"artifact_id":"d3830ed1-4cb6-4607-ba4c-4db81678dba1","artifact_dir":null,"primary_filename":null,"accessory_filenames":null,"folder_layout_version":1,"migrated_to_folder_at":null,"hypothesis_id":null,"authorship":{"kind":"human","contributors":[{"role":"author","actor_ref":"system"}]},"epistemic_tier":"T3_provisional","created_by_agent_id":null},"outgoing_links":[{"target_artifact_id":"paper-40281419","link_type":"derives_from","strength":1.0,"evidence":"paper_figure metadata/provenance references PMID 40281419"}],"incoming_links":[],"current_artifact_id":"paper-figure-40281419-4","is_canonical":true,"supersede_chain":["paper-figure-40281419-4"]}