{"artifact":{"id":"wiki-apoe4","artifact_type":"wiki_page","entity_ids":"[\"apoe4\"]","title":"apoe4","quality_score":0.7,"created_by":"import","provenance_chain":null,"content_hash":"6a3cd133afdc063b7e09d9e3a6c5366baec2df398ba59d758add1d2bf55b257e","metadata":{"summary":null,"archived_at":"2026-05-13 16:31:36.170273-07","entity_type":"disease","neurowiki_url":"https://neurowiki.xyz/wiki/diseases/apoe4","_schema_version":1,"archived_reason":"wiki_page_missing"},"created_at":"2026-04-02T04:21:26-07:00","updated_at":"2026-04-02T12:45:32-07:00","version_number":5,"parent_version_id":null,"version_tag":null,"changelog":null,"is_latest":1,"lifecycle_state":"archived","superseded_by":null,"deprecated_at":null,"deprecated_reason":null,"dependencies":null,"market_price":0.5,"origin_type":"internal","origin_url":null,"lifecycle_changed_at":"2026-05-13T16:31:36.170273-07:00","citation_count":0,"embed_count":0,"derivation_count":0,"support_count":0,"contradiction_count":0,"total_usage":0.0,"usage_score":0.5,"usage_computed_at":null,"quality_status":"ok","contributors":[],"answers_question_ids":null,"deprecated_reason_detail":null,"deprecated_reason_code":null,"commit_sha":null,"commit_submodule":null,"last_mutated_at":"2026-05-16T14:51:34.657673-07:00","disputed_at":null,"gap_id":null,"mission_id":null,"intrinsic_priority":null,"effective_priority":null,"artifact_id":"dbf60819-797f-4462-85f2-8cc8007784dc","artifact_dir":null,"primary_filename":null,"accessory_filenames":null,"folder_layout_version":1,"migrated_to_folder_at":null,"hypothesis_id":null,"authorship":{"kind":"human","contributors":[{"role":"author","actor_ref":"import"}]},"epistemic_tier":"T3_provisional","created_by_agent_id":null},"outgoing_links":[{"target_artifact_id":"hypothesis-h-637a53c9","link_type":"mentions","strength":0.5,"evidence":"Related to disease: neurodegeneration"},{"target_artifact_id":"hypothesis-h-44195347","link_type":"mentions","strength":0.8,"evidence":"Hypothesis targets gene APOE"},{"target_artifact_id":"hypothesis-h-d0a564e8","link_type":"mentions","strength":0.8,"evidence":"Hypothesis targets gene APOE"},{"target_artifact_id":"hypothesis-h-11795af0","link_type":"mentions","strength":0.8,"evidence":"Hypothesis targets gene APOE"},{"target_artifact_id":"hypothesis-h-9a108e26","link_type":"mentions","strength":0.5,"evidence":"Related to disease: neurodegeneration"},{"target_artifact_id":"analysis-sda-2026-04-01-gap-010","link_type":"mentions","strength":0.5,"evidence":"Shared entity in analysis"},{"target_artifact_id":"experiment-exp-wiki-experiments-apoe4-function-alzheimers","link_type":"mentions","strength":0.7,"evidence":"Experiment targets E4"},{"target_artifact_id":"experiment-exp-debate-0a5edc59c7b9","link_type":"mentions","strength":0.4,"evidence":"Related to disease: Neurodegeneration"},{"target_artifact_id":"hypothesis-h-b948c32c","link_type":"mentions","strength":0.7,"evidence":"Wiki page entity match on gene APOE"},{"target_artifact_id":"hypothesis-h-99b4e2d2","link_type":"mentions","strength":0.7,"evidence":"Wiki page entity match on gene APOE"},{"target_artifact_id":"hypothesis-h-a20e0cbb","link_type":"mentions","strength":0.7,"evidence":"Wiki page entity match on gene APOE"},{"target_artifact_id":"wiki-tau","link_type":"related","strength":0.6,"evidence":"KG edge: interacts_with"},{"target_artifact_id":"wiki-neuroinflammation","link_type":"related","strength":0.6,"evidence":"KG edge: causes"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-010","link_type":"mentions","strength":0.4,"evidence":"Wiki page matches analysis keyword 'apoe4'"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-010","link_type":"related","strength":0.5,"evidence":"Auto: transitive via hypothesis"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-008","link_type":"related","strength":0.5,"evidence":"Auto: transitive via hypothesis"},{"target_artifact_id":"hypothesis-h-seaad-fa5ea82d","link_type":"mentions","strength":0.5,"evidence":"Entity APOE4 in hypothesis description"},{"target_artifact_id":"hypothesis-h-c9c79e3e","link_type":"mentions","strength":0.6,"evidence":"Wiki page 'apoe4' — entity matches hypothesis target"},{"target_artifact_id":"hypothesis-h-0758b337","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'apoe4' — entity matches hypothesis target"},{"target_artifact_id":"hypothesis-h-7d4a24d3","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'apoe4' — entity matches hypothesis target"},{"target_artifact_id":"hypothesis-h-84808267","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'apoe4' — entity matches hypothesis target"},{"target_artifact_id":"hypothesis-h-1e564178","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'apoe4' — entity matches hypothesis target"},{"target_artifact_id":"hypothesis-h-807d7a82","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'apoe4' — entity matches hypothesis target"},{"target_artifact_id":"hypothesis-h-470ff83e","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'apoe4' — entity matches hypothesis target"},{"target_artifact_id":"hypothesis-h-97aa8486","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'apoe4' — entity matches hypothesis target"},{"target_artifact_id":"hypothesis-h-9e9fee95","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'apoe4' — entity matches hypothesis target"},{"target_artifact_id":"hypothesis-h-50a535f9","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'apoe4' — entity matches hypothesis target"},{"target_artifact_id":"hypothesis-h-881362dc","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'apoe4' — entity matches hypothesis target"},{"target_artifact_id":"hypothesis-h-fd52a7a0","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'apoe4' — entity matches hypothesis target"},{"target_artifact_id":"hypothesis-h-de579caf","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'apoe4' — entity matches hypothesis target"},{"target_artifact_id":"hypothesis-h-2600483e","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'apoe4' — entity matches hypothesis target"},{"target_artifact_id":"hypothesis-h-441b25ba","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'apoe4' — entity matches hypothesis target"},{"target_artifact_id":"hypothesis-h-b234254c","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'apoe4' — entity matches hypothesis target"},{"target_artifact_id":"hypothesis-h-55ef81c5","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'apoe4' — entity matches hypothesis target"},{"target_artifact_id":"hypothesis-h-fdaae8d9","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'apoe4' — entity matches hypothesis target"},{"target_artifact_id":"hypothesis-h-bdbd2120","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'apoe4' — entity matches hypothesis target"},{"target_artifact_id":"hypothesis-h-856feb98","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'apoe4' — entity matches hypothesis target"},{"target_artifact_id":"hypothesis-h-4bb7fd8c","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'apoe4' — entity matches hypothesis target"},{"target_artifact_id":"hypothesis-h-addc0a61","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'apoe4' — entity matches hypothesis target"},{"target_artifact_id":"hypothesis-h-8fe389e8","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'apoe4' — entity matches hypothesis target"},{"target_artifact_id":"hypothesis-h-0e614ae4","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'apoe4' — entity matches hypothesis target"},{"target_artifact_id":"hypothesis-h-seaad-51323624","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'apoe4' — entity matches hypothesis target"},{"target_artifact_id":"hypothesis-h-seaad-56fa6428","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'apoe4' — entity matches hypothesis target"},{"target_artifact_id":"hypothesis-h-seaad-v4-26ba859b","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'apoe4' — entity matches hypothesis target"},{"target_artifact_id":"hypothesis-h-seaad-v4-29e81bbc","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'apoe4' — entity matches hypothesis target"},{"target_artifact_id":"hypothesis-h-a87702b6","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'apoe4' — entity matches hypothesis target"},{"target_artifact_id":"hypothesis-h-29ef94d5","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'apoe4' — entity matches hypothesis target"},{"target_artifact_id":"hypothesis-h-e23f05fb","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'apoe4' — entity matches hypothesis target"},{"target_artifact_id":"hypothesis-h-075f1f02","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'apoe4' — entity matches hypothesis target"},{"target_artifact_id":"hypothesis-h-2f43b42f","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'apoe4' — entity matches hypothesis target"},{"target_artifact_id":"hypothesis-h-3d545f4e","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'apoe4' — entity matches hypothesis target"},{"target_artifact_id":"hypothesis-h-51e7234f","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'apoe4' — entity matches hypothesis target"},{"target_artifact_id":"hypothesis-h-5d943bfc","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'apoe4' — entity matches hypothesis target"},{"target_artifact_id":"hypothesis-h-180807e5","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'apoe4' — entity matches hypothesis target"},{"target_artifact_id":"hypothesis-h-58e655ee","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'apoe4' — entity matches hypothesis target"},{"target_artifact_id":"hypothesis-h-15336069","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'apoe4' — entity matches hypothesis target"},{"target_artifact_id":"analysis-SDA-2026-04-02-gap-tau-prop-20260402003221","link_type":"mentions","strength":0.65,"evidence":"Wiki page 'apoe4' — entity appears in KG edges for analysis"},{"target_artifact_id":"analysis-SDA-2026-04-02-gap-epigenetic-reprog-b685190e","link_type":"mentions","strength":0.65,"evidence":"Wiki page 'apoe4' — entity appears in KG edges for analysis"},{"target_artifact_id":"analysis-SDA-2026-04-02-26abc5e5f9f2","link_type":"mentions","strength":0.65,"evidence":"Wiki page 'apoe4' — entity appears in KG edges for analysis"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-v2-68d9c9c1","link_type":"mentions","strength":0.65,"evidence":"Wiki page 'apoe4' — entity appears in KG edges for analysis"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-008","link_type":"mentions","strength":0.65,"evidence":"Wiki page 'apoe4' — entity appears in KG edges for analysis"},{"target_artifact_id":"hypothesis-h-15336069","link_type":"related","strength":0.7,"evidence":"Wiki title matches hypothesis target gene: apoe"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-007","link_type":"related","strength":0.4,"evidence":"{\"via\": \"hypothesis_parent\"}"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-012","link_type":"related","strength":0.4,"evidence":"{\"via\": \"hypothesis_parent\"}"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-013","link_type":"related","strength":0.4,"evidence":"{\"via\": \"hypothesis_parent\"}"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-014","link_type":"related","strength":0.4,"evidence":"{\"via\": \"hypothesis_parent\"}"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-20260401-225149","link_type":"related","strength":0.4,"evidence":"{\"via\": \"hypothesis_parent\"}"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-auto-fd6b1635d9","link_type":"related","strength":0.5599999999999999,"evidence":"{\"via\": \"hypothesis_parent\"}"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-lipid-rafts-2026-04-01","link_type":"related","strength":0.4,"evidence":"{\"via\": \"hypothesis_parent\"}"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-v2-18cf98ca","link_type":"related","strength":0.4,"evidence":"{\"via\": \"hypothesis_parent\"}"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-v2-bc5f270e","link_type":"related","strength":0.4,"evidence":"{\"via\": \"hypothesis_parent\"}"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-v2-ee5a5023","link_type":"related","strength":0.4,"evidence":"{\"via\": \"hypothesis_parent\"}"},{"target_artifact_id":"analysis-SDA-2026-04-02-gap-aging-mouse-brain-20260402","link_type":"related","strength":0.4,"evidence":"{\"via\": \"hypothesis_parent\"}"},{"target_artifact_id":"analysis-SDA-2026-04-02-gap-crispr-neurodegeneration-20260402","link_type":"related","strength":0.4,"evidence":"{\"via\": \"hypothesis_parent\"}"},{"target_artifact_id":"analysis-SDA-2026-04-02-gap-seaad-v4-20260402065846","link_type":"related","strength":0.4,"evidence":"{\"via\": \"hypothesis_parent\"}"},{"target_artifact_id":"analysis-SDA-2026-04-02-gap-v2-5d0e3052","link_type":"related","strength":0.4,"evidence":"{\"via\": \"hypothesis_parent\"}"},{"target_artifact_id":"analysis-analysis-SEAAD-20260402","link_type":"related","strength":0.4,"evidence":"{\"via\": \"hypothesis_parent\"}"}],"incoming_links":[{"source_artifact_id":"hypothesis-h-c9c79e3e","link_type":"related","strength":0.54,"evidence":"Reverse: Wiki page 'apoe4' — entity matches hypothesis target"},{"source_artifact_id":"hypothesis-h-15336069","link_type":"related","strength":0.63,"evidence":"Reverse: Wiki title matches hypothesis target gene: apoe"},{"source_artifact_id":"hypothesis-h-44195347","link_type":"related","strength":0.7200000000000001,"evidence":"Reverse: Hypothesis targets gene APOE"},{"source_artifact_id":"hypothesis-h-d0a564e8","link_type":"related","strength":0.7200000000000001,"evidence":"Reverse: Hypothesis targets gene APOE"},{"source_artifact_id":"hypothesis-h-11795af0","link_type":"related","strength":0.7200000000000001,"evidence":"Reverse: Hypothesis targets gene APOE"},{"source_artifact_id":"experiment-exp-wiki-experiments-apoe4-function-alzheimers","link_type":"related","strength":0.63,"evidence":"Reverse: Experiment targets E4"},{"source_artifact_id":"hypothesis-h-b948c32c","link_type":"related","strength":0.63,"evidence":"Reverse: Wiki page entity match on gene APOE"},{"source_artifact_id":"hypothesis-h-99b4e2d2","link_type":"related","strength":0.63,"evidence":"Reverse: Wiki page entity match on gene APOE"},{"source_artifact_id":"hypothesis-h-a20e0cbb","link_type":"related","strength":0.63,"evidence":"Reverse: Wiki page entity match on gene APOE"},{"source_artifact_id":"analysis-SDA-2026-04-01-gap-008","link_type":"related","strength":0.5,"evidence":"Reverse link"},{"source_artifact_id":"analysis-SDA-2026-04-01-gap-v2-68d9c9c1","link_type":"related","strength":0.5,"evidence":"Reverse link"},{"source_artifact_id":"analysis-SDA-2026-04-02-26abc5e5f9f2","link_type":"related","strength":0.5,"evidence":"Reverse link"},{"source_artifact_id":"analysis-SDA-2026-04-02-gap-epigenetic-reprog-b685190e","link_type":"related","strength":0.5,"evidence":"Reverse link"},{"source_artifact_id":"analysis-SDA-2026-04-02-gap-tau-prop-20260402003221","link_type":"related","strength":0.5,"evidence":"Reverse link"},{"source_artifact_id":"analysis-sda-2026-04-01-gap-010","link_type":"related","strength":0.5,"evidence":"Reverse link"},{"source_artifact_id":"hypothesis-h-637a53c9","link_type":"related","strength":0.4,"evidence":"Auto: reverse of wiki→hypothesis"},{"source_artifact_id":"hypothesis-h-9a108e26","link_type":"related","strength":0.4,"evidence":"Auto: reverse of wiki→hypothesis"},{"source_artifact_id":"analysis-SDA-2026-04-01-gap-010","link_type":"related","strength":0.6,"evidence":"Analysis discusses entity covered by wiki page"},{"source_artifact_id":"figure-88c09d4e2588","link_type":"related","strength":0.5,"evidence":"Linked via gene extracted from figure title: APOE4"}],"current_artifact_id":"wiki-apoe4","is_canonical":true,"supersede_chain":["wiki-apoe4"]}