{"artifact":{"id":"wiki-biomarkers-p-tau-181","artifact_type":"wiki_page","entity_ids":"[\"biomarkers-p-tau-181\"]","title":"Phosphorylated Tau 181 (p-tau 181)","quality_score":0.5,"created_by":"crosslink-migration","provenance_chain":"[]","content_hash":"555905e5fe01118fdf06be4501bf5647602065e3b50a37f14e2a14dd072c9261","metadata":{"slug":"biomarkers-p-tau-181","kg_node_id":null,"entity_type":"biomarker","origin_type":"v1_polymorphic_backfill","source_table":"wiki_pages","wiki_page_id":"wp-e18118faf5b7","__merged_from":{"merged_at":"2026-05-13","unprefixed_id":"biomarkers-p-tau-181"},"_schema_version":1},"created_at":"2026-04-02T07:20:05-07:00","updated_at":"2026-04-02T13:40:08-07:00","version_number":5,"parent_version_id":null,"version_tag":null,"changelog":null,"is_latest":1,"lifecycle_state":"active","superseded_by":null,"deprecated_at":null,"deprecated_reason":null,"dependencies":null,"market_price":0.5,"origin_type":"internal","origin_url":null,"lifecycle_changed_at":"2026-04-02T13:40:08-07:00","citation_count":0,"embed_count":0,"derivation_count":0,"support_count":0,"contradiction_count":0,"total_usage":0.0,"usage_score":0.5,"usage_computed_at":null,"quality_status":"ok","contributors":[],"answers_question_ids":null,"deprecated_reason_detail":null,"deprecated_reason_code":null,"commit_sha":null,"commit_submodule":null,"last_mutated_at":"2026-05-16T14:51:34.657673-07:00","disputed_at":null,"gap_id":null,"mission_id":null,"intrinsic_priority":null,"effective_priority":null,"artifact_id":"5e942ec8-8756-4310-879d-3ccb685d2ea2","artifact_dir":null,"primary_filename":null,"accessory_filenames":null,"folder_layout_version":1,"migrated_to_folder_at":null,"hypothesis_id":null,"authorship":{"kind":"human","contributors":[{"role":"author","actor_ref":"crosslink-migration"}]},"epistemic_tier":"T3_provisional","created_by_agent_id":null},"outgoing_links":[{"target_artifact_id":"experiment-exp-eaf169e6-564f-4431-8060-d8f56667a994","link_type":"mentions","strength":0.44999999999999996,"evidence":"Content: CDK5 mentioned 2x in wiki/biomarkers-p-tau-181"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-012","link_type":"mentions","strength":0.4,"evidence":"Wiki page matches analysis keyword 'biomarkers'"},{"target_artifact_id":"hypothesis-h-019ad538","link_type":"mentions","strength":0.55,"evidence":"Keyword 'PHOSPHORYLATED' from wiki title in hypothesis text"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-009","link_type":"related","strength":0.385,"evidence":"Via hypothesis: Keyword 'PHOSPHORYLATED' from wiki title in hypothesis text"},{"target_artifact_id":"hypothesis-h-49791706","link_type":"mentions","strength":0.55,"evidence":"Keyword 'PHOSPHORYLATED' from wiki title in hypothesis text"},{"target_artifact_id":"hypothesis-h-18a0fcc6","link_type":"mentions","strength":0.55,"evidence":"Keyword 'PHOSPHORYLATED' from wiki title in hypothesis text"},{"target_artifact_id":"analysis-SDA-2026-04-02-gap-tau-prop-20260402003221","link_type":"related","strength":0.385,"evidence":"Via hypothesis: Keyword 'PHOSPHORYLATED' from wiki title in hypothesis text"},{"target_artifact_id":"hypothesis-h-881362dc","link_type":"mentions","strength":0.55,"evidence":"Keyword 'PHOSPHORYLATED' from wiki title in hypothesis text"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-v2-bc5f270e","link_type":"related","strength":0.385,"evidence":"Via hypothesis: Keyword 'PHOSPHORYLATED' from wiki title in hypothesis text"},{"target_artifact_id":"hypothesis-h-7e0b5ade","link_type":"mentions","strength":0.55,"evidence":"Keyword 'PHOSPHORYLATED' from wiki title in hypothesis text"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-008","link_type":"related","strength":0.385,"evidence":"Via hypothesis: Keyword 'PHOSPHORYLATED' from wiki title in hypothesis text"},{"target_artifact_id":"hypothesis-h-dca3e907","link_type":"mentions","strength":0.55,"evidence":"Keyword 'PHOSPHORYLATED' from wiki title in hypothesis text"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-006","link_type":"related","strength":0.385,"evidence":"Via hypothesis: Keyword 'PHOSPHORYLATED' from wiki title in hypothesis text"},{"target_artifact_id":"hypothesis-h-a1b56d74","link_type":"mentions","strength":0.55,"evidence":"Keyword 'PHOSPHORYLATED' from wiki title in hypothesis text"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-007","link_type":"related","strength":0.385,"evidence":"Via hypothesis: Keyword 'PHOSPHORYLATED' from wiki title in hypothesis text"},{"target_artifact_id":"hypothesis-h-0e0cc0c1","link_type":"mentions","strength":0.55,"evidence":"Keyword 'PHOSPHORYLATED' from wiki title in hypothesis text"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-012","link_type":"related","strength":0.385,"evidence":"Via hypothesis: Keyword 'PHOSPHORYLATED' from wiki title in hypothesis text"},{"target_artifact_id":"hypothesis-h-4bb7fd8c","link_type":"mentions","strength":0.55,"evidence":"Keyword 'PHOSPHORYLATED' from wiki title in hypothesis text"},{"target_artifact_id":"analysis-SDA-2026-04-02-gap-epigenetic-reprog-b685190e","link_type":"related","strength":0.385,"evidence":"Via hypothesis: Keyword 'PHOSPHORYLATED' from wiki title in hypothesis text"},{"target_artifact_id":"hypothesis-h-05b8894a","link_type":"mentions","strength":0.55,"evidence":"Keyword 'PHOSPHORYLATED' from wiki title in hypothesis text"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-005","link_type":"related","strength":0.385,"evidence":"Via hypothesis: Keyword 'PHOSPHORYLATED' from wiki title in hypothesis text"},{"target_artifact_id":"hypothesis-h-0e675a41","link_type":"mentions","strength":0.55,"evidence":"Keyword 'PHOSPHORYLATED' from wiki title in hypothesis text"},{"target_artifact_id":"hypothesis-h-6c83282d","link_type":"mentions","strength":0.55,"evidence":"Keyword 'PHOSPHORYLATED' from wiki title in hypothesis text"},{"target_artifact_id":"hypothesis-h-seaad-51323624","link_type":"mentions","strength":0.55,"evidence":"Keyword 'PHOSPHORYLATED' from wiki title in hypothesis text"},{"target_artifact_id":"analysis-analysis-SEAAD-20260402","link_type":"related","strength":0.385,"evidence":"Via hypothesis: Keyword 'PHOSPHORYLATED' from wiki title in hypothesis text"},{"target_artifact_id":"hypothesis-h-4fabd9ce","link_type":"mentions","strength":0.55,"evidence":"Keyword 'PHOSPHORYLATED' from wiki title in hypothesis text"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-v2-68d9c9c1","link_type":"related","strength":0.385,"evidence":"Via hypothesis: Keyword 'PHOSPHORYLATED' from wiki title in hypothesis text"},{"target_artifact_id":"hypothesis-h-83efeed6","link_type":"mentions","strength":0.55,"evidence":"Keyword 'PHOSPHORYLATED' from wiki title in hypothesis text"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-014","link_type":"related","strength":0.385,"evidence":"Via hypothesis: Keyword 'PHOSPHORYLATED' from wiki title in hypothesis text"},{"target_artifact_id":"hypothesis-h-1fe4ba9b","link_type":"mentions","strength":0.55,"evidence":"Keyword 'PHOSPHORYLATED' from wiki title in hypothesis text"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-v2-691b42f1","link_type":"related","strength":0.385,"evidence":"Via hypothesis: Keyword 'PHOSPHORYLATED' from wiki title in hypothesis text"},{"target_artifact_id":"hypothesis-h-0791836f","link_type":"mentions","strength":0.55,"evidence":"Keyword 'PHOSPHORYLATED' from wiki title in hypothesis text"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-011","link_type":"related","strength":0.385,"evidence":"Via hypothesis: Keyword 'PHOSPHORYLATED' from wiki title in hypothesis text"},{"target_artifact_id":"hypothesis-h-637a53c9","link_type":"mentions","strength":0.55,"evidence":"Keyword 'PHOSPHORYLATED' from wiki title in hypothesis text"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-010","link_type":"related","strength":0.385,"evidence":"Via hypothesis: Keyword 'PHOSPHORYLATED' from wiki title in hypothesis text"},{"target_artifact_id":"hypothesis-h-11795af0","link_type":"mentions","strength":0.55,"evidence":"Keyword 'PHOSPHORYLATED' from wiki title in hypothesis text"},{"target_artifact_id":"hypothesis-h-73e4340b","link_type":"mentions","strength":0.55,"evidence":"Keyword 'PHOSPHORYLATED' from wiki title in hypothesis text"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-v2-ee5a5023","link_type":"related","strength":0.385,"evidence":"Via hypothesis: Keyword 'PHOSPHORYLATED' from wiki title in hypothesis text"},{"target_artifact_id":"hypothesis-h-5dbfd3aa","link_type":"mentions","strength":0.55,"evidence":"Keyword 'PHOSPHORYLATED' from wiki title in hypothesis text"},{"target_artifact_id":"hypothesis-h-b7898b79","link_type":"mentions","strength":0.55,"evidence":"Keyword 'PHOSPHORYLATED' from wiki title in hypothesis text"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-v2-18cf98ca","link_type":"related","strength":0.385,"evidence":"Via hypothesis: Keyword 'PHOSPHORYLATED' from wiki title in hypothesis text"},{"target_artifact_id":"hypothesis-h-ae1b2beb","link_type":"mentions","strength":0.55,"evidence":"Keyword 'PHOSPHORYLATED' from wiki title in hypothesis text"},{"target_artifact_id":"hypothesis-h-044ee057","link_type":"mentions","strength":0.55,"evidence":"Keyword 'PHOSPHORYLATED' from wiki title in hypothesis text"},{"target_artifact_id":"hypothesis-h-23a3cc07","link_type":"mentions","strength":0.55,"evidence":"Keyword 'PHOSPHORYLATED' from wiki title in hypothesis text"},{"target_artifact_id":"hypothesis-h-76888762","link_type":"mentions","strength":0.55,"evidence":"Keyword 'PHOSPHORYLATED' from wiki title in hypothesis text"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-004","link_type":"related","strength":0.385,"evidence":"Via hypothesis: Keyword 'PHOSPHORYLATED' from wiki title in hypothesis text"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-auto-fd6b1635d9","link_type":"related","strength":0.385,"evidence":"Via hypothesis: Keyword 'PHOSPHORYLATED' from wiki title in hypothesis text"},{"target_artifact_id":"hypothesis-h-0f00fd75","link_type":"mentions","strength":0.55,"evidence":"Keyword 'PHOSPHORYLATED' from wiki title in hypothesis text"},{"target_artifact_id":"hypothesis-h-fffd1a74","link_type":"mentions","strength":0.55,"evidence":"Keyword 'PHOSPHORYLATED' from wiki title in hypothesis text"},{"target_artifact_id":"hypothesis-h-98b431ba","link_type":"mentions","strength":0.55,"evidence":"Keyword 'PHOSPHORYLATED' from wiki title in hypothesis text"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-v2-89432b95","link_type":"related","strength":0.385,"evidence":"Via hypothesis: Keyword 'PHOSPHORYLATED' from wiki title in hypothesis text"},{"target_artifact_id":"hypothesis-h-c8ccbee8","link_type":"related","strength":0.5,"evidence":"Wiki relates to pathway: glymphatic clearance"},{"target_artifact_id":"hypothesis-h-aa2d317c","link_type":"related","strength":0.5,"evidence":"Wiki relates to pathway: Blood-brain barrier transport"},{"target_artifact_id":"hypothesis-h-62e56eb9","link_type":"related","strength":0.5,"evidence":"Wiki relates to pathway: glymphatic clearance"},{"target_artifact_id":"hypothesis-h-b3d6ecc2","link_type":"related","strength":0.5,"evidence":"Wiki relates to pathway: degradation"},{"target_artifact_id":"hypothesis-h-8ef34c4c","link_type":"related","strength":0.5,"evidence":"Wiki relates to pathway: degradation"},{"target_artifact_id":"hypothesis-h-8986b8af","link_type":"related","strength":0.5,"evidence":"Wiki relates to pathway: degradation"},{"target_artifact_id":"hypothesis-h-35f04e1b","link_type":"related","strength":0.5,"evidence":"Wiki relates to pathway: Vascular"},{"target_artifact_id":"hypothesis-h-807d7a82","link_type":"related","strength":0.5,"evidence":"Wiki relates to pathway: glymphatic clearance"},{"target_artifact_id":"hypothesis-h-9e9fee95","link_type":"related","strength":0.5,"evidence":"Wiki relates to pathway: glymphatic clearance"},{"target_artifact_id":"hypothesis-h-fb56c8a0","link_type":"related","strength":0.5,"evidence":"Wiki relates to pathway: Vascular"},{"target_artifact_id":"hypothesis-h-de579caf","link_type":"related","strength":0.5,"evidence":"Wiki relates to pathway: glymphatic clearance"},{"target_artifact_id":"hypothesis-h-4113b0e8","link_type":"related","strength":0.5,"evidence":"Wiki relates to pathway: Tau protein"},{"target_artifact_id":"hypothesis-h-73e29e3a","link_type":"related","strength":0.5,"evidence":"Wiki relates to pathway: Tau protein"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-20260401-225149","link_type":"related","strength":0.385,"evidence":"Via hypothesis: Keyword 'PHOSPHORYLATED' from wiki title in hypothesis text"}],"incoming_links":[{"source_artifact_id":"analysis-SDA-2026-04-01-gap-004","link_type":"related","strength":0.5,"evidence":"Reverse link"},{"source_artifact_id":"analysis-SDA-2026-04-01-gap-005","link_type":"related","strength":0.5,"evidence":"Reverse link"},{"source_artifact_id":"analysis-SDA-2026-04-01-gap-006","link_type":"related","strength":0.5,"evidence":"Reverse link"},{"source_artifact_id":"analysis-SDA-2026-04-01-gap-007","link_type":"related","strength":0.5,"evidence":"Reverse link"},{"source_artifact_id":"analysis-SDA-2026-04-01-gap-008","link_type":"related","strength":0.5,"evidence":"Reverse link"},{"source_artifact_id":"analysis-SDA-2026-04-01-gap-009","link_type":"related","strength":0.5,"evidence":"Reverse link"},{"source_artifact_id":"analysis-SDA-2026-04-01-gap-010","link_type":"related","strength":0.5,"evidence":"Reverse link"},{"source_artifact_id":"analysis-SDA-2026-04-01-gap-011","link_type":"related","strength":0.5,"evidence":"Reverse link"},{"source_artifact_id":"analysis-SDA-2026-04-01-gap-012","link_type":"related","strength":0.5,"evidence":"Reverse link"},{"source_artifact_id":"analysis-SDA-2026-04-01-gap-014","link_type":"related","strength":0.5,"evidence":"Reverse link"},{"source_artifact_id":"analysis-SDA-2026-04-01-gap-auto-fd6b1635d9","link_type":"related","strength":0.5,"evidence":"Reverse link"},{"source_artifact_id":"analysis-SDA-2026-04-01-gap-v2-18cf98ca","link_type":"related","strength":0.5,"evidence":"Reverse link"},{"source_artifact_id":"analysis-SDA-2026-04-01-gap-v2-68d9c9c1","link_type":"related","strength":0.5,"evidence":"Reverse link"},{"source_artifact_id":"analysis-SDA-2026-04-01-gap-v2-691b42f1","link_type":"related","strength":0.5,"evidence":"Reverse link"},{"source_artifact_id":"analysis-SDA-2026-04-01-gap-v2-89432b95","link_type":"related","strength":0.5,"evidence":"Reverse link"},{"source_artifact_id":"analysis-SDA-2026-04-01-gap-v2-bc5f270e","link_type":"related","strength":0.5,"evidence":"Reverse link"},{"source_artifact_id":"analysis-SDA-2026-04-01-gap-v2-ee5a5023","link_type":"related","strength":0.5,"evidence":"Reverse link"},{"source_artifact_id":"analysis-SDA-2026-04-02-gap-epigenetic-reprog-b685190e","link_type":"related","strength":0.5,"evidence":"Reverse link"},{"source_artifact_id":"analysis-SDA-2026-04-02-gap-tau-prop-20260402003221","link_type":"related","strength":0.5,"evidence":"Reverse link"},{"source_artifact_id":"analysis-analysis-SEAAD-20260402","link_type":"related","strength":0.5,"evidence":"Reverse link"},{"source_artifact_id":"analysis-SDA-2026-04-01-gap-20260401-225149","link_type":"related","strength":0.5,"evidence":"Reverse link"},{"source_artifact_id":"open_question-biomarkers-p-tau-181-dced0cca","link_type":"derives_from","strength":0.9,"evidence":"{\"method\": \"open_question_wiki_crosslink\", \"cycle\": \"artifact-enrichment-2026-04-27\"}"},{"source_artifact_id":"open_question-biomarkers-p-tau-181-621a8b65","link_type":"derives_from","strength":0.9,"evidence":"{\"method\": \"open_question_wiki_crosslink\", \"cycle\": \"artifact-enrichment-2026-04-27\"}"},{"source_artifact_id":"open_question-biomarkers-p-tau-181-c9020656","link_type":"derives_from","strength":0.9,"evidence":"{\"method\": \"open_question_wiki_crosslink\", \"cycle\": \"artifact-enrichment-2026-04-27\"}"},{"source_artifact_id":"open_question-biomarkers-p-tau-181-a44baf33","link_type":"derives_from","strength":0.9,"evidence":"{\"method\": \"open_question_wiki_crosslink\", \"cycle\": \"artifact-enrichment-2026-04-27\"}"},{"source_artifact_id":"open_question-biomarkers-p-tau-181-0f9c84d2","link_type":"derives_from","strength":0.9,"evidence":"{\"method\": \"open_question_wiki_crosslink\", \"cycle\": \"artifact-enrichment-2026-04-27\"}"},{"source_artifact_id":"open_question-biomarkers-p-tau-181-cd569303","link_type":"derives_from","strength":0.9,"evidence":"{\"method\": \"open_question_wiki_crosslink\", \"cycle\": \"artifact-enrichment-2026-04-27\"}"},{"source_artifact_id":"open_question-biomarkers-p-tau-181-b465a34e","link_type":"derives_from","strength":0.9,"evidence":"{\"method\": \"open_question_wiki_crosslink\", \"cycle\": \"artifact-enrichment-2026-04-27\"}"},{"source_artifact_id":"open_question-biomarkers-p-tau-181-842b6075","link_type":"derives_from","strength":0.9,"evidence":"{\"method\": \"open_question_wiki_crosslink\", \"cycle\": \"artifact-enrichment-2026-04-27\"}"},{"source_artifact_id":"open_question-biomarkers-p-tau-181-70825c19","link_type":"derives_from","strength":0.9,"evidence":"{\"method\": \"open_question_wiki_crosslink\", \"cycle\": \"artifact-enrichment-2026-04-27\"}"}],"current_artifact_id":"wiki-biomarkers-p-tau-181","is_canonical":true,"supersede_chain":["wiki-biomarkers-p-tau-181"]}