{"artifact":{"id":"wiki-cell-types-microglial-cells-hierarchy","artifact_type":"wiki_page","entity_ids":"[\"cell-types-microglial-cells-hierarchy\"]","title":"Microglial Cells — Cell Type Hierarchy","quality_score":0.5,"created_by":"crosslink-migration","provenance_chain":"[]","content_hash":"9a145dcb6088ef3b52e27ba89d40034b2fb488d2c6db86c4c0122e900c4097fa","metadata":{"slug":"cell-types-microglial-cells-hierarchy","kg_node_id":null,"entity_type":"cell","origin_type":"v1_polymorphic_backfill","source_table":"wiki_pages","wiki_page_id":"wp-05990662f6a6","__merged_from":{"merged_at":"2026-05-13","unprefixed_id":"cell-types-microglial-cells-hierarchy"},"_schema_version":1},"created_at":"2026-04-02T07:19:36-07:00","updated_at":"2026-04-02T13:40:08-07:00","version_number":5,"parent_version_id":null,"version_tag":null,"changelog":null,"is_latest":1,"lifecycle_state":"active","superseded_by":null,"deprecated_at":null,"deprecated_reason":null,"dependencies":null,"market_price":0.5,"origin_type":"internal","origin_url":null,"lifecycle_changed_at":"2026-04-02T13:40:08-07:00","citation_count":0,"embed_count":0,"derivation_count":0,"support_count":0,"contradiction_count":0,"total_usage":0.0,"usage_score":0.5,"usage_computed_at":null,"quality_status":"ok","contributors":[],"answers_question_ids":null,"deprecated_reason_detail":null,"deprecated_reason_code":null,"commit_sha":null,"commit_submodule":null,"last_mutated_at":"2026-05-16T14:51:34.657673-07:00","disputed_at":null,"gap_id":null,"mission_id":null,"intrinsic_priority":null,"effective_priority":null,"artifact_id":"8a1aa71d-a8ec-4a81-980a-55925a19ba14","artifact_dir":null,"primary_filename":null,"accessory_filenames":null,"folder_layout_version":1,"migrated_to_folder_at":null,"hypothesis_id":null,"authorship":{"kind":"human","contributors":[{"role":"author","actor_ref":"crosslink-migration"}]},"epistemic_tier":"T3_provisional","created_by_agent_id":null},"outgoing_links":[{"target_artifact_id":"experiment-exp-bb10fa2f-bb6f-44ae-9f89-df2e93103cc2","link_type":"mentions","strength":0.5,"evidence":"Content: IBA1 mentioned 3x in wiki/cell-types-microglial-cells-hierarchy"},{"target_artifact_id":"experiment-exp-6b9425de-646a-4089-a7c4-5d2a2ce28f9d","link_type":"mentions","strength":0.5,"evidence":"Content: IBA1 mentioned 3x in wiki/cell-types-microglial-cells-hierarchy"},{"target_artifact_id":"experiment-exp-239399a1-7dd6-4b43-a7ef-1c130df4dbda","link_type":"mentions","strength":0.5,"evidence":"Content: P2RY12 mentioned 5x in wiki/cell-types-microglial-cells-hierarchy"},{"target_artifact_id":"experiment-exp-a2de27b1-2d71-4b2f-9da1-e7cfc9bb108c","link_type":"mentions","strength":0.5,"evidence":"Content: P2RY12 mentioned 5x in wiki/cell-types-microglial-cells-hierarchy"},{"target_artifact_id":"experiment-exp-f90ceea7-76be-4e57-80d0-981b67b113f8","link_type":"mentions","strength":0.5,"evidence":"Content: P2RY12 mentioned 5x in wiki/cell-types-microglial-cells-hierarchy"},{"target_artifact_id":"hypothesis-h-61196ade","link_type":"mentions","strength":0.6,"evidence":"Content: TREM2 mentioned 32x in wiki/cell-types-microglial-cells-hierarchy"},{"target_artifact_id":"experiment-exp-3b7faafc-4bd9-407f-ae87-8cfbd6237e51","link_type":"mentions","strength":0.5,"evidence":"Content: APOE4 mentioned 3x in wiki/cell-types-microglial-cells-hierarchy"},{"target_artifact_id":"experiment-exp-wiki-experiments-er-golgi-secretory-pathway-parkinsons","link_type":"mentions","strength":1.0,"evidence":"Wiki page mentions experiment exp-wiki-experiments-er-golgi-secretory-pathway-parkinsons: ...Design](/experiment/exp-wiki-experiments-er-golgi-secretory-pathway-parkinsons)\n\n..."},{"target_artifact_id":"hypothesis-h-3d545f4e","link_type":"mentions","strength":1.0,"evidence":"Wiki page mentions hypothesis h-3d545f4e: ...lation](/hypotheses/h-3d545f4e)\n- [Purinergic P2Y1..."},{"target_artifact_id":"hypothesis-h-5ff6c5ca","link_type":"mentions","strength":0.5,"evidence":"Wiki page title/slug matches hypothesis keyword 'Cell'"},{"target_artifact_id":"hypothesis-h-57862f8a","link_type":"mentions","strength":0.5,"evidence":"Wiki page title/slug matches hypothesis keyword 'Cell'"},{"target_artifact_id":"hypothesis-h-5daecb6e","link_type":"mentions","strength":0.5,"evidence":"Wiki page title/slug matches hypothesis keyword 'Microglial'"},{"target_artifact_id":"hypothesis-h-84808267","link_type":"mentions","strength":0.5,"evidence":"Wiki page title/slug matches hypothesis keyword 'Cell'"},{"target_artifact_id":"hypothesis-h-1a34778f","link_type":"mentions","strength":0.5,"evidence":"Wiki page title/slug matches hypothesis keyword 'Cell'"},{"target_artifact_id":"hypothesis-h-470ff83e","link_type":"mentions","strength":0.5,"evidence":"Wiki page title/slug matches hypothesis keyword 'Microglial'"},{"target_artifact_id":"hypothesis-h-38292315","link_type":"mentions","strength":0.5,"evidence":"Wiki page title/slug matches hypothesis keyword 'Microglial'"},{"target_artifact_id":"hypothesis-h-782b40b1","link_type":"mentions","strength":0.5,"evidence":"Wiki page title/slug matches hypothesis keyword 'Microglial'"},{"target_artifact_id":"hypothesis-h-b234254c","link_type":"mentions","strength":0.5,"evidence":"Wiki page title/slug matches hypothesis keyword 'microglial'"},{"target_artifact_id":"analysis-SDA-2026-04-02-gap-microglial-subtypes-20260402004119","link_type":"mentions","strength":0.4,"evidence":"Wiki page matches analysis keyword 'microglial'"},{"target_artifact_id":"analysis-SDA-2026-04-02-gap-seaad-20260402025452","link_type":"mentions","strength":0.4,"evidence":"Wiki page matches analysis keyword 'types'"},{"target_artifact_id":"analysis-SDA-2026-04-02-gap-seaad-v2-20260402032945","link_type":"mentions","strength":0.4,"evidence":"Wiki page matches analysis keyword 'types'"},{"target_artifact_id":"hypothesis-h-f99ce4ca","link_type":"mentions","strength":0.6,"evidence":"Content: P2RY12 mentioned 5x in wiki/cell-types-microglial-cells-hierarchy"},{"target_artifact_id":"hypothesis-h-ba3a948a","link_type":"mentions","strength":0.6,"evidence":"Content: CX3CR1 mentioned 8x in wiki/cell-types-microglial-cells-hierarchy"},{"target_artifact_id":"experiment-exp-debate-385d65cb42cb","link_type":"mentions","strength":0.5,"evidence":"Content: CX3CR1 mentioned 8x in wiki/cell-types-microglial-cells-hierarchy"},{"target_artifact_id":"hypothesis-h-044ee057","link_type":"mentions","strength":0.6,"evidence":"Content: TREM2 mentioned 31x in wiki/cell-types-microglial-cells-hierarchy"},{"target_artifact_id":"experiment-exp-wiki-experiments-trem2-function-alzheimers","link_type":"mentions","strength":0.5,"evidence":"Content: TREM2 mentioned 31x in wiki/cell-types-microglial-cells-hierarchy"},{"target_artifact_id":"experiment-exp-wiki-experiments-trem2-agonist-parkinsons","link_type":"mentions","strength":0.5,"evidence":"Content: TREM2 mentioned 31x in wiki/cell-types-microglial-cells-hierarchy"},{"target_artifact_id":"experiment-exp-wiki-experiments-trem2-agonist-efficacy","link_type":"mentions","strength":0.5,"evidence":"Content: TREM2 mentioned 31x in wiki/cell-types-microglial-cells-hierarchy"},{"target_artifact_id":"hypothesis-h-d0a564e8","link_type":"mentions","strength":0.6,"evidence":"Content: APOE mentioned 4x in wiki/cell-types-microglial-cells-hierarchy"},{"target_artifact_id":"hypothesis-h-11795af0","link_type":"mentions","strength":0.6,"evidence":"Content: APOE mentioned 4x in wiki/cell-types-microglial-cells-hierarchy"},{"target_artifact_id":"hypothesis-h-b948c32c","link_type":"mentions","strength":0.6,"evidence":"Content: APOE mentioned 4x in wiki/cell-types-microglial-cells-hierarchy"},{"target_artifact_id":"experiment-exp-wiki-experiments-ad-amyloid-resilient-phenotype","link_type":"mentions","strength":0.5,"evidence":"Content: APOE mentioned 4x in wiki/cell-types-microglial-cells-hierarchy"},{"target_artifact_id":"experiment-exp-wiki-experiments-sex-differences-alzheimers","link_type":"mentions","strength":0.5,"evidence":"Content: APOE mentioned 4x in wiki/cell-types-microglial-cells-hierarchy"},{"target_artifact_id":"experiment-exp-wiki-experiments-ad-combination-therapy-trial","link_type":"mentions","strength":0.5,"evidence":"Content: APOE mentioned 4x in wiki/cell-types-microglial-cells-hierarchy"},{"target_artifact_id":"hypothesis-h-856feb98","link_type":"mentions","strength":0.55,"evidence":"Content: BDNF mentioned 3x in wiki/cell-types-microglial-cells-hierarchy"},{"target_artifact_id":"hypothesis-h-e0183502","link_type":"mentions","strength":0.55,"evidence":"Content: BDNF mentioned 3x in wiki/cell-types-microglial-cells-hierarchy"},{"target_artifact_id":"hypothesis-h-ee1df336","link_type":"mentions","strength":0.55,"evidence":"Content: BDNF mentioned 3x in wiki/cell-types-microglial-cells-hierarchy"},{"target_artifact_id":"experiment-exp-wiki-experiments-alpha-synuclein-aggregation-triggers-sporadic-pd","link_type":"mentions","strength":0.5,"evidence":"Content: BDNF mentioned 3x in wiki/cell-types-microglial-cells-hierarchy"},{"target_artifact_id":"experiment-exp-wiki-experiments-brain-connectivity-tacs-alzheimers","link_type":"mentions","strength":0.5,"evidence":"Content: BDNF mentioned 3x in wiki/cell-types-microglial-cells-hierarchy"},{"target_artifact_id":"experiment-exp-wiki-experiments-microbiome-gut-barrier-als","link_type":"mentions","strength":0.5,"evidence":"Content: BDNF mentioned 3x in wiki/cell-types-microglial-cells-hierarchy"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-004","link_type":"related","strength":0.3,"evidence":"Transitive: wiki→hypothesis→analysis"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-005","link_type":"related","strength":0.3,"evidence":"Transitive: wiki→hypothesis→analysis"},{"target_artifact_id":"experiment-exp-wiki-experiments-er-golgi-secretory-pathway-parkinsons","link_type":"related","strength":0.7,"evidence":"Wiki page for ER related to experiment"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-v2-691b42f1","link_type":"related","strength":0.5,"evidence":"Auto: transitive via hypothesis"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-010","link_type":"related","strength":0.5,"evidence":"Auto: transitive via hypothesis"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-013","link_type":"related","strength":0.5,"evidence":"Auto: transitive via hypothesis"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-014","link_type":"related","strength":0.5,"evidence":"Auto: transitive via hypothesis"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-008","link_type":"related","strength":0.5,"evidence":"Auto: transitive via hypothesis"},{"target_artifact_id":"analysis-SDA-2026-04-02-26abc5e5f9f2","link_type":"related","strength":0.5,"evidence":"Auto: transitive via hypothesis"},{"target_artifact_id":"analysis-SDA-2026-04-02-gap-tau-prop-20260402003221","link_type":"related","strength":0.5,"evidence":"Auto: transitive via hypothesis"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-012","link_type":"related","strength":0.5,"evidence":"Auto: transitive via hypothesis"},{"target_artifact_id":"hypothesis-h-3d545f4e","link_type":"related","strength":0.7,"evidence":"Cross-linked via Microglial match"},{"target_artifact_id":"hypothesis-h-5daecb6e","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"target_artifact_id":"hypothesis-h-470ff83e","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"target_artifact_id":"hypothesis-h-38292315","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"target_artifact_id":"hypothesis-h-782b40b1","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"target_artifact_id":"hypothesis-h-b234254c","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"target_artifact_id":"hypothesis-h-61196ade","link_type":"related","strength":0.35,"evidence":"Title keyword"},{"target_artifact_id":"hypothesis-h-019ad538","link_type":"related","strength":0.5,"evidence":"Wiki content mentions gene CLOCK"},{"target_artifact_id":"hypothesis-h-15336069","link_type":"related","strength":0.5,"evidence":"Wiki content mentions gene APOE"},{"target_artifact_id":"hypothesis-h-180807e5","link_type":"related","strength":0.5,"evidence":"Wiki content mentions gene TREM2"},{"target_artifact_id":"hypothesis-h-3460f820","link_type":"related","strength":0.5,"evidence":"Wiki content mentions gene TREM2"},{"target_artifact_id":"hypothesis-h-44195347","link_type":"related","strength":0.5,"evidence":"Wiki content mentions gene APOE"},{"target_artifact_id":"hypothesis-h-c8ccbee8","link_type":"mentions","strength":0.5,"evidence":"Wiki content mentions gene AQP4"},{"target_artifact_id":"hypothesis-h-62e56eb9","link_type":"mentions","strength":0.5,"evidence":"Wiki content mentions gene AQP4"},{"target_artifact_id":"hypothesis-h-807d7a82","link_type":"mentions","strength":0.5,"evidence":"Wiki content mentions gene AQP4"},{"target_artifact_id":"hypothesis-h-5706bbd7","link_type":"mentions","strength":0.5,"evidence":"Wiki content mentions gene BMAL1"},{"target_artifact_id":"hypothesis-h-b7898b79","link_type":"mentions","strength":0.5,"evidence":"Wiki content mentions gene CLOCK"},{"target_artifact_id":"hypothesis-h-99b4e2d2","link_type":"mentions","strength":0.5,"evidence":"Wiki content mentions gene APOE"},{"target_artifact_id":"hypothesis-h-a20e0cbb","link_type":"mentions","strength":0.5,"evidence":"Wiki content mentions gene APOE"},{"target_artifact_id":"hypothesis-h-seaad-fa5ea82d","link_type":"mentions","strength":0.5,"evidence":"Wiki content mentions gene APOE"},{"target_artifact_id":"hypothesis-h-c9c79e3e","link_type":"mentions","strength":0.5,"evidence":"Wiki content mentions gene APOE"},{"target_artifact_id":"hypothesis-h-seaad-51323624","link_type":"mentions","strength":0.5,"evidence":"Wiki content mentions gene TREM2"},{"target_artifact_id":"hypothesis-h-seaad-56fa6428","link_type":"mentions","strength":0.5,"evidence":"Wiki content mentions gene GFAP"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-20260401-225149","link_type":"related","strength":0.5,"evidence":"Auto: transitive via hypothesis"}],"incoming_links":[{"source_artifact_id":"hypothesis-h-61196ade","link_type":"related","strength":0.54,"evidence":"Reverse: Content: TREM2 mentioned 32x in wiki/cell-types-microglial-cells-hierarchy"},{"source_artifact_id":"hypothesis-h-f99ce4ca","link_type":"related","strength":0.54,"evidence":"Reverse: Content: P2RY12 mentioned 5x in wiki/cell-types-microglial-cells-hierarchy"},{"source_artifact_id":"hypothesis-h-ba3a948a","link_type":"related","strength":0.54,"evidence":"Reverse: Content: CX3CR1 mentioned 8x in wiki/cell-types-microglial-cells-hierarchy"},{"source_artifact_id":"hypothesis-h-044ee057","link_type":"related","strength":0.54,"evidence":"Reverse: Content: TREM2 mentioned 31x in wiki/cell-types-microglial-cells-hierarchy"},{"source_artifact_id":"hypothesis-h-d0a564e8","link_type":"related","strength":0.54,"evidence":"Reverse: Content: APOE mentioned 4x in wiki/cell-types-microglial-cells-hierarchy"},{"source_artifact_id":"hypothesis-h-11795af0","link_type":"related","strength":0.54,"evidence":"Reverse: Content: APOE mentioned 4x in wiki/cell-types-microglial-cells-hierarchy"},{"source_artifact_id":"hypothesis-h-b948c32c","link_type":"related","strength":0.54,"evidence":"Reverse: Content: APOE mentioned 4x in wiki/cell-types-microglial-cells-hierarchy"},{"source_artifact_id":"experiment-exp-wiki-experiments-er-golgi-secretory-pathway-parkinsons","link_type":"related","strength":0.7,"evidence":"Experiment targets ER described in wiki"},{"source_artifact_id":"hypothesis-h-5ff6c5ca","link_type":"related","strength":0.4,"evidence":"Auto: reverse of wiki→hypothesis"},{"source_artifact_id":"hypothesis-h-57862f8a","link_type":"related","strength":0.4,"evidence":"Auto: reverse of wiki→hypothesis"},{"source_artifact_id":"hypothesis-h-5daecb6e","link_type":"related","strength":0.4,"evidence":"Auto: reverse of wiki→hypothesis"},{"source_artifact_id":"hypothesis-h-84808267","link_type":"related","strength":0.4,"evidence":"Auto: reverse of wiki→hypothesis"},{"source_artifact_id":"hypothesis-h-1a34778f","link_type":"related","strength":0.4,"evidence":"Auto: reverse of wiki→hypothesis"},{"source_artifact_id":"hypothesis-h-470ff83e","link_type":"related","strength":0.4,"evidence":"Auto: reverse of wiki→hypothesis"},{"source_artifact_id":"hypothesis-h-38292315","link_type":"related","strength":0.4,"evidence":"Auto: reverse of wiki→hypothesis"},{"source_artifact_id":"hypothesis-h-782b40b1","link_type":"related","strength":0.4,"evidence":"Auto: reverse of wiki→hypothesis"},{"source_artifact_id":"hypothesis-h-b234254c","link_type":"related","strength":0.4,"evidence":"Auto: reverse of wiki→hypothesis"},{"source_artifact_id":"hypothesis-h-856feb98","link_type":"related","strength":0.4,"evidence":"Auto: reverse of wiki→hypothesis"},{"source_artifact_id":"hypothesis-h-e0183502","link_type":"related","strength":0.4,"evidence":"Auto: reverse of wiki→hypothesis"},{"source_artifact_id":"hypothesis-h-ee1df336","link_type":"related","strength":0.4,"evidence":"Auto: reverse of wiki→hypothesis"},{"source_artifact_id":"hypothesis-h-3d545f4e","link_type":"related","strength":0.7,"evidence":"Cross-linked via Microglial match"},{"source_artifact_id":"analysis-SDA-2026-04-01-gap-004","link_type":"related","strength":0.5,"evidence":"Reverse link"},{"source_artifact_id":"analysis-SDA-2026-04-01-gap-005","link_type":"related","strength":0.5,"evidence":"Reverse link"},{"source_artifact_id":"analysis-SDA-2026-04-01-gap-008","link_type":"related","strength":0.5,"evidence":"Reverse link"},{"source_artifact_id":"analysis-SDA-2026-04-01-gap-010","link_type":"related","strength":0.5,"evidence":"Reverse link"},{"source_artifact_id":"analysis-SDA-2026-04-01-gap-012","link_type":"related","strength":0.5,"evidence":"Reverse link"},{"source_artifact_id":"analysis-SDA-2026-04-01-gap-013","link_type":"related","strength":0.5,"evidence":"Reverse link"},{"source_artifact_id":"analysis-SDA-2026-04-01-gap-014","link_type":"related","strength":0.5,"evidence":"Reverse link"},{"source_artifact_id":"analysis-SDA-2026-04-01-gap-v2-691b42f1","link_type":"related","strength":0.5,"evidence":"Reverse link"},{"source_artifact_id":"analysis-SDA-2026-04-02-26abc5e5f9f2","link_type":"related","strength":0.5,"evidence":"Reverse link"},{"source_artifact_id":"analysis-SDA-2026-04-02-gap-microglial-subtypes-20260402004119","link_type":"related","strength":0.5,"evidence":"Reverse link"},{"source_artifact_id":"analysis-SDA-2026-04-02-gap-seaad-20260402025452","link_type":"related","strength":0.5,"evidence":"Reverse link"},{"source_artifact_id":"analysis-SDA-2026-04-02-gap-seaad-v2-20260402032945","link_type":"related","strength":0.5,"evidence":"Reverse link"},{"source_artifact_id":"analysis-SDA-2026-04-02-gap-tau-prop-20260402003221","link_type":"related","strength":0.5,"evidence":"Reverse link"},{"source_artifact_id":"analysis-SDA-2026-04-01-gap-20260401-225149","link_type":"related","strength":0.5,"evidence":"Reverse link"}],"current_artifact_id":"wiki-cell-types-microglial-cells-hierarchy","is_canonical":true,"supersede_chain":["wiki-cell-types-microglial-cells-hierarchy"]}