{"artifact":{"id":"wiki-clinical-trials-daridorexant-post-cardiotomy-delirium-nct07217912","artifact_type":"wiki_page","entity_ids":"[\"clinical-trials-daridorexant-post-cardiotomy-delirium-nct07217912\"]","title":"Daridorexant for Post-Cardiotomy Delirium Prevention (NCT07217912)","quality_score":0.5,"created_by":"crosslink-migration","provenance_chain":"[]","content_hash":"8d51b99a408a47509051aa224cbb9492a30f93401140637ff63f77146930089b","metadata":{"slug":"clinical-trials-daridorexant-post-cardiotomy-delirium-nct07217912","kg_node_id":null,"entity_type":"clinical","origin_type":"v1_polymorphic_backfill","source_table":"wiki_pages","wiki_page_id":"wp-019d5f5ce932","__merged_from":{"merged_at":"2026-05-13","unprefixed_id":"clinical-trials-daridorexant-post-cardiotomy-delirium-nct07217912"},"_schema_version":1},"created_at":"2026-04-02T07:19:03-07:00","updated_at":"2026-04-02T13:40:08-07:00","version_number":5,"parent_version_id":null,"version_tag":null,"changelog":null,"is_latest":1,"lifecycle_state":"active","superseded_by":null,"deprecated_at":null,"deprecated_reason":null,"dependencies":null,"market_price":0.5,"origin_type":"internal","origin_url":null,"lifecycle_changed_at":"2026-04-02T13:40:08-07:00","citation_count":0,"embed_count":0,"derivation_count":0,"support_count":0,"contradiction_count":0,"total_usage":0.0,"usage_score":0.5,"usage_computed_at":null,"quality_status":"ok","contributors":[],"answers_question_ids":null,"deprecated_reason_detail":null,"deprecated_reason_code":null,"commit_sha":null,"commit_submodule":null,"last_mutated_at":"2026-05-16T14:51:34.657673-07:00","disputed_at":null,"gap_id":null,"mission_id":null,"intrinsic_priority":null,"effective_priority":null,"artifact_id":"92621350-f810-4b3e-8ce3-1c56123914ba","artifact_dir":null,"primary_filename":null,"accessory_filenames":null,"folder_layout_version":1,"migrated_to_folder_at":null,"hypothesis_id":null,"authorship":{"kind":"human","contributors":[{"role":"author","actor_ref":"crosslink-migration"}]},"epistemic_tier":"T3_provisional","created_by_agent_id":null},"outgoing_links":[{"target_artifact_id":"hypothesis-h-9e9fee95","link_type":"mentions","strength":0.55,"evidence":"Content: HCRTR2 mentioned 3x in wiki/clinical-trials-daridorexant-post-cardiotomy-delirium-nct07217912"},{"target_artifact_id":"experiment-exp-wiki-experiments-nph-glymphatic-interaction","link_type":"mentions","strength":0.5,"evidence":"Content: HCRTR2 mentioned 3x in wiki/clinical-trials-daridorexant-post-cardiotomy-delirium-nct07217912"},{"target_artifact_id":"experiment-exp-wiki-diagnostics-nph-csf-dynamic-biomarkers-differential-diagnosi","link_type":"mentions","strength":0.5,"evidence":"Content: HCRTR1 mentioned 3x in wiki/clinical-trials-daridorexant-post-cardiotomy-delirium-nct07217912"},{"target_artifact_id":"experiment-exp-wiki-experiments-sleep-respiratory-als","link_type":"mentions","strength":0.5,"evidence":"Content: HCRTR1 mentioned 3x in wiki/clinical-trials-daridorexant-post-cardiotomy-delirium-nct07217912"},{"target_artifact_id":"hypothesis-h-eea667a9","link_type":"mentions","strength":0.5,"evidence":"Wiki page title/slug matches hypothesis keyword 'Prevention'"},{"target_artifact_id":"hypothesis-h-e7e1f943","link_type":"mentions","strength":0.5,"evidence":"Wiki page title/slug matches hypothesis keyword 'Prevention'"},{"target_artifact_id":"experiment-exp-wiki-experiments-oligodendrocyte-myelin-dysfunction-parkinsons","link_type":"related","strength":0.7,"evidence":"Wiki page for ID related to experiment"},{"target_artifact_id":"experiment-exp-wiki-experiments-neural-oscillation-dysfunction-parkinsons","link_type":"related","strength":0.7,"evidence":"Wiki page for ID related to experiment"},{"target_artifact_id":"experiment-exp-wiki-experiments-proteasome-ubiquitin-system-dysfunction-parkinso","link_type":"related","strength":0.7,"evidence":"Wiki page for ID related to experiment"},{"target_artifact_id":"experiment-exp-wiki-experiments-microbiome-alpha-synuclein-propagation","link_type":"related","strength":0.7,"evidence":"Wiki page for ID related to experiment"},{"target_artifact_id":"experiment-exp-wiki-experiments-stress-granule-dysfunction-parkinsons","link_type":"related","strength":0.7,"evidence":"Wiki page for ID related to experiment"},{"target_artifact_id":"experiment-exp-wiki-experiments-animal-model-comparison-neurodegeneration","link_type":"related","strength":0.7,"evidence":"Wiki page for ID related to experiment"},{"target_artifact_id":"experiment-exp-wiki-experiments-protein-aggregation-kinetic-validation","link_type":"related","strength":0.7,"evidence":"Wiki page for ID related to experiment"},{"target_artifact_id":"experiment-exp-wiki-experiments-tht-validation-protein-aggregation","link_type":"related","strength":0.7,"evidence":"Wiki page for ID related to experiment"},{"target_artifact_id":"experiment-exp-wiki-experiments-endocannabinoid-system-dysfunction-parkinsons","link_type":"related","strength":0.7,"evidence":"Wiki page for ID related to experiment"},{"target_artifact_id":"experiment-exp-wiki-experiments-glymphatic-circadian-axis-parkinsons","link_type":"related","strength":0.7,"evidence":"Wiki page for ID related to experiment"},{"target_artifact_id":"experiment-exp-wiki-experiments-regulated-necrosis-parkinsons","link_type":"related","strength":0.7,"evidence":"Wiki page for ID related to experiment"},{"target_artifact_id":"experiment-exp-wiki-experiments-lipid-droplet-lysosome-axis-parkinsons","link_type":"related","strength":0.7,"evidence":"Wiki page for CT related to experiment"},{"target_artifact_id":"experiment-exp-wiki-experiments-purinergic-signaling-parkinsons","link_type":"related","strength":0.7,"evidence":"Wiki page for ID related to experiment"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-v2-68d9c9c1","link_type":"related","strength":0.5,"evidence":"Auto: transitive via hypothesis"},{"target_artifact_id":"hypothesis-h-8b7727c1","link_type":"related","strength":0.7,"evidence":"Cross-linked via Prevent match"},{"target_artifact_id":"hypothesis-h-8597755b","link_type":"mentions","strength":0.65,"evidence":"Wiki page content mentions hypothesis target gene: HCRTR2"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-20260401-225149","link_type":"related","strength":0.5,"evidence":"{\"via\":\"hypothesis_parent\"}"},{"target_artifact_id":"hypothesis-h-6b84d8e2","link_type":"mentions","strength":0.5,"evidence":"Wiki content mentions gene HCRT"},{"target_artifact_id":"hypothesis-h-d40d2659","link_type":"related","strength":0.5,"evidence":"Wiki relates to pathway: neuronal excitability"},{"target_artifact_id":"hypothesis-h-c8ccbee8","link_type":"related","strength":0.5,"evidence":"Wiki relates to pathway: glymphatic clearance"},{"target_artifact_id":"hypothesis-h-62e56eb9","link_type":"related","strength":0.5,"evidence":"Wiki relates to pathway: glymphatic clearance"},{"target_artifact_id":"hypothesis-h-1e564178","link_type":"related","strength":0.5,"evidence":"Wiki relates to pathway: stress response"},{"target_artifact_id":"hypothesis-h-807d7a82","link_type":"related","strength":0.5,"evidence":"Wiki relates to pathway: glymphatic clearance"},{"target_artifact_id":"hypothesis-h-83efeed6","link_type":"related","strength":0.5,"evidence":"Wiki relates to pathway: Circadian rhythm"},{"target_artifact_id":"hypothesis-h-9e9fee95","link_type":"related","strength":0.5,"evidence":"Wiki relates to pathway: Circadian rhythm"},{"target_artifact_id":"hypothesis-h-de579caf","link_type":"related","strength":0.5,"evidence":"Wiki relates to pathway: Circadian rhythm"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-20260401-225149","link_type":"related","strength":0.5,"evidence":"Auto: transitive via hypothesis"}],"incoming_links":[{"source_artifact_id":"hypothesis-h-8597755b","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Wiki page content mentions hypothesis target gene: HCRTR2"},{"source_artifact_id":"experiment-exp-wiki-experiments-oligodendrocyte-myelin-dysfunction-parkinsons","link_type":"related","strength":0.7,"evidence":"Experiment targets ID described in wiki"},{"source_artifact_id":"experiment-exp-wiki-experiments-neural-oscillation-dysfunction-parkinsons","link_type":"related","strength":0.7,"evidence":"Experiment targets ID described in wiki"},{"source_artifact_id":"experiment-exp-wiki-experiments-proteasome-ubiquitin-system-dysfunction-parkinso","link_type":"related","strength":0.7,"evidence":"Experiment targets ID described in wiki"},{"source_artifact_id":"experiment-exp-wiki-experiments-microbiome-alpha-synuclein-propagation","link_type":"related","strength":0.7,"evidence":"Experiment targets ID described in wiki"},{"source_artifact_id":"experiment-exp-wiki-experiments-stress-granule-dysfunction-parkinsons","link_type":"related","strength":0.7,"evidence":"Experiment targets ID described in wiki"},{"source_artifact_id":"experiment-exp-wiki-experiments-animal-model-comparison-neurodegeneration","link_type":"related","strength":0.7,"evidence":"Experiment targets ID described in wiki"},{"source_artifact_id":"experiment-exp-wiki-experiments-protein-aggregation-kinetic-validation","link_type":"related","strength":0.7,"evidence":"Experiment targets ID described in wiki"},{"source_artifact_id":"experiment-exp-wiki-experiments-tht-validation-protein-aggregation","link_type":"related","strength":0.7,"evidence":"Experiment targets ID described in wiki"},{"source_artifact_id":"experiment-exp-wiki-experiments-endocannabinoid-system-dysfunction-parkinsons","link_type":"related","strength":0.7,"evidence":"Experiment targets ID described in wiki"},{"source_artifact_id":"experiment-exp-wiki-experiments-glymphatic-circadian-axis-parkinsons","link_type":"related","strength":0.7,"evidence":"Experiment targets ID described in wiki"},{"source_artifact_id":"experiment-exp-wiki-experiments-regulated-necrosis-parkinsons","link_type":"related","strength":0.7,"evidence":"Experiment targets ID described in wiki"},{"source_artifact_id":"experiment-exp-wiki-experiments-lipid-droplet-lysosome-axis-parkinsons","link_type":"related","strength":0.7,"evidence":"Experiment targets CT described in wiki"},{"source_artifact_id":"experiment-exp-wiki-experiments-purinergic-signaling-parkinsons","link_type":"related","strength":0.7,"evidence":"Experiment targets ID described in wiki"},{"source_artifact_id":"hypothesis-h-eea667a9","link_type":"related","strength":0.4,"evidence":"Auto: reverse of wiki→hypothesis"},{"source_artifact_id":"hypothesis-h-e7e1f943","link_type":"related","strength":0.4,"evidence":"Auto: reverse of wiki→hypothesis"},{"source_artifact_id":"hypothesis-h-8b7727c1","link_type":"related","strength":0.7,"evidence":"Cross-linked via Prevent match"},{"source_artifact_id":"analysis-SDA-2026-04-01-gap-v2-68d9c9c1","link_type":"related","strength":0.5,"evidence":"Reverse link"},{"source_artifact_id":"analysis-SDA-2026-04-01-gap-20260401-225149","link_type":"related","strength":0.5,"evidence":"Reverse link"}],"current_artifact_id":"wiki-clinical-trials-daridorexant-post-cardiotomy-delirium-nct07217912","is_canonical":true,"supersede_chain":["wiki-clinical-trials-daridorexant-post-cardiotomy-delirium-nct07217912"]}