{"artifact":{"id":"wiki-companies-ono-pharmaceutical","artifact_type":"wiki_page","entity_ids":"[\"companies-ono-pharmaceutical\"]","title":"Ono Pharmaceutical","quality_score":0.5,"created_by":"crosslink-migration","provenance_chain":"[]","content_hash":"ffec2497234d64476d19a07d76795b28c941087766dfb34b17b1bf48961fd1d0","metadata":{"slug":"companies-ono-pharmaceutical","kg_node_id":null,"entity_type":"company","origin_type":"v1_polymorphic_backfill","source_table":"wiki_pages","wiki_page_id":"wp-47ce89996953","__merged_from":{"merged_at":"2026-05-13","unprefixed_id":"companies-ono-pharmaceutical"},"_schema_version":1},"created_at":"2026-04-02T07:20:07-07:00","updated_at":"2026-04-02T13:40:08-07:00","version_number":5,"parent_version_id":null,"version_tag":null,"changelog":null,"is_latest":1,"lifecycle_state":"active","superseded_by":null,"deprecated_at":null,"deprecated_reason":null,"dependencies":null,"market_price":0.5,"origin_type":"internal","origin_url":null,"lifecycle_changed_at":"2026-04-02T13:40:08-07:00","citation_count":0,"embed_count":0,"derivation_count":0,"support_count":0,"contradiction_count":0,"total_usage":0.0,"usage_score":0.5,"usage_computed_at":null,"quality_status":"ok","contributors":[],"answers_question_ids":null,"deprecated_reason_detail":null,"deprecated_reason_code":null,"commit_sha":null,"commit_submodule":null,"last_mutated_at":"2026-05-16T14:51:34.657673-07:00","disputed_at":null,"gap_id":null,"mission_id":null,"intrinsic_priority":null,"effective_priority":null,"artifact_id":"cb0f3da1-eaad-46bd-859e-46ac3624a725","artifact_dir":null,"primary_filename":null,"accessory_filenames":null,"folder_layout_version":1,"migrated_to_folder_at":null,"hypothesis_id":null,"authorship":{"kind":"human","contributors":[{"role":"author","actor_ref":"crosslink-migration"}]},"epistemic_tier":"T3_provisional","created_by_agent_id":null},"outgoing_links":[{"target_artifact_id":"wiki-proteins-parkin","link_type":"mentions","strength":0.4,"evidence":"Wiki 'Ono Pharmaceutical' content mentions protein 'Parkin'"},{"target_artifact_id":"wiki-proteins-tau","link_type":"mentions","strength":0.4,"evidence":"Wiki 'Ono Pharmaceutical' content mentions protein 'Tau Protein'"},{"target_artifact_id":"wiki-genes-bace1","link_type":"mentions","strength":0.4,"evidence":"Wiki 'Ono Pharmaceutical' content mentions gene 'bace1'"},{"target_artifact_id":"wiki-genes-trem2","link_type":"mentions","strength":0.4,"evidence":"Wiki 'Ono Pharmaceutical' content mentions gene 'TREM2 — Triggering Receptor Expressed on Myeloid Cells 2'"},{"target_artifact_id":"wiki-diseases-alzheimers-disease","link_type":"mentions","strength":0.4,"evidence":"Wiki 'Ono Pharmaceutical' content mentions disease 'Alzheimer's Disease'"},{"target_artifact_id":"wiki-diseases-cancer","link_type":"mentions","strength":0.4,"evidence":"Wiki 'Ono Pharmaceutical' content mentions disease 'Cancer'"},{"target_artifact_id":"wiki-diseases-neurodegeneration","link_type":"mentions","strength":0.4,"evidence":"Wiki 'Ono Pharmaceutical' content mentions disease 'Neurodegeneration'"},{"target_artifact_id":"wiki-diseases-migraine","link_type":"mentions","strength":0.4,"evidence":"Wiki 'Ono Pharmaceutical' content mentions disease 'Migraine'"},{"target_artifact_id":"wiki-diseases-parkinsons-disease","link_type":"mentions","strength":0.4,"evidence":"Wiki 'Ono Pharmaceutical' content mentions disease 'Parkinson's Disease'"},{"target_artifact_id":"hypothesis-h-044ee057","link_type":"mentions","strength":0.45,"evidence":"Wiki 'Ono Pharmaceutical' content mentions gene 'TREM2'"},{"target_artifact_id":"hypothesis-h-b234254c","link_type":"mentions","strength":0.45,"evidence":"Wiki 'Ono Pharmaceutical' content mentions gene 'TREM2'"},{"target_artifact_id":"hypothesis-h-441b25ba","link_type":"mentions","strength":0.45,"evidence":"Wiki 'Ono Pharmaceutical' content mentions gene 'BACE1'"},{"target_artifact_id":"hypothesis-h-e12109e3","link_type":"related","strength":0.4,"evidence":"Wiki 'Ono Pharmaceutical' content mentions disease 'NEURODEGENERATION'"},{"target_artifact_id":"hypothesis-h-76888762","link_type":"related","strength":0.4,"evidence":"Wiki 'Ono Pharmaceutical' content mentions disease 'NEURODEGENERATION'"},{"target_artifact_id":"hypothesis-h-d2df6eaf","link_type":"related","strength":0.4,"evidence":"Wiki 'Ono Pharmaceutical' content mentions disease 'NEURODEGENERATION'"},{"target_artifact_id":"hypothesis-h-4dd0d19b","link_type":"related","strength":0.4,"evidence":"Wiki 'Ono Pharmaceutical' content mentions disease 'ALZHEIMER'S DISEASE'"},{"target_artifact_id":"hypothesis-h-b234254c","link_type":"related","strength":0.4,"evidence":"Wiki 'Ono Pharmaceutical' content mentions disease 'ALZHEIMER'S DISEASE'"},{"target_artifact_id":"hypothesis-h-55ef81c5","link_type":"related","strength":0.4,"evidence":"Wiki 'Ono Pharmaceutical' content mentions disease 'ALZHEIMER'S DISEASE'"},{"target_artifact_id":"experiment-exp-wiki-experiments-macroautophagy-dysfunction-parkinsons","link_type":"related","strength":0.7,"evidence":"Wiki page for MA related to experiment"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-v2-691b42f1","link_type":"related","strength":0.5,"evidence":"Auto: transitive via hypothesis"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-lipid-rafts-2026-04-01","link_type":"related","strength":0.5,"evidence":"Auto: transitive via hypothesis"},{"target_artifact_id":"analysis-SDA-2026-04-02-gap-tau-prop-20260402003221","link_type":"related","strength":0.5,"evidence":"Auto: transitive via hypothesis"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-004","link_type":"related","strength":0.5,"evidence":"Auto: transitive via hypothesis"},{"target_artifact_id":"hypothesis-h-180807e5","link_type":"related","strength":0.5,"evidence":"Wiki content mentions gene TREM2"},{"target_artifact_id":"hypothesis-h-3460f820","link_type":"related","strength":0.5,"evidence":"Wiki content mentions gene TREM2"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-9137255b","link_type":"related","strength":0.5,"evidence":"{\"via\":\"hypothesis_parent\"}"},{"target_artifact_id":"hypothesis-h-seaad-51323624","link_type":"mentions","strength":0.5,"evidence":"Wiki content mentions gene TREM2"},{"target_artifact_id":"hypothesis-h-61196ade","link_type":"mentions","strength":0.5,"evidence":"Wiki content mentions gene TREM2"},{"target_artifact_id":"hypothesis-h-e7e1f943","link_type":"mentions","strength":0.65,"evidence":"Title match: Ono Pharmaceutical"}],"incoming_links":[{"source_artifact_id":"hypothesis-h-e7e1f943","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Title match: Ono Pharmaceutical"},{"source_artifact_id":"experiment-exp-wiki-experiments-macroautophagy-dysfunction-parkinsons","link_type":"related","strength":0.7,"evidence":"Experiment targets MA described in wiki"},{"source_artifact_id":"hypothesis-h-044ee057","link_type":"related","strength":0.4,"evidence":"Auto: reverse of wiki→hypothesis"},{"source_artifact_id":"hypothesis-h-b234254c","link_type":"related","strength":0.4,"evidence":"Auto: reverse of wiki→hypothesis"},{"source_artifact_id":"hypothesis-h-441b25ba","link_type":"related","strength":0.4,"evidence":"Auto: reverse of wiki→hypothesis"},{"source_artifact_id":"analysis-SDA-2026-04-01-gap-004","link_type":"related","strength":0.5,"evidence":"Reverse link"},{"source_artifact_id":"analysis-SDA-2026-04-01-gap-lipid-rafts-2026-04-01","link_type":"related","strength":0.5,"evidence":"Reverse link"},{"source_artifact_id":"analysis-SDA-2026-04-01-gap-v2-691b42f1","link_type":"related","strength":0.5,"evidence":"Reverse link"},{"source_artifact_id":"analysis-SDA-2026-04-02-gap-tau-prop-20260402003221","link_type":"related","strength":0.5,"evidence":"Reverse link"}],"current_artifact_id":"wiki-companies-ono-pharmaceutical","is_canonical":true,"supersede_chain":["wiki-companies-ono-pharmaceutical"]}