{"artifact":{"id":"wiki-genes-chat","artifact_type":"wiki_page","entity_ids":"[\"CHAT\"]","title":"CHAT Gene","quality_score":0.5,"created_by":"crosslink-migration","provenance_chain":"[]","content_hash":"bf58d40252c08fe6947c79538ffdf98d04624d3a536dadeed98e31607b66cfb0","metadata":{"slug":"genes-chat","kg_node_id":"CHAT","entity_type":"gene","origin_type":"v1_polymorphic_backfill","source_table":"wiki_pages","wiki_page_id":"wp-3f95c9e8cc57","__merged_from":{"merged_at":"2026-05-13","unprefixed_id":"genes-chat"},"_schema_version":1},"created_at":"2026-04-02T07:19:24-07:00","updated_at":"2026-04-02T13:40:08-07:00","version_number":5,"parent_version_id":null,"version_tag":null,"changelog":null,"is_latest":1,"lifecycle_state":"active","superseded_by":null,"deprecated_at":null,"deprecated_reason":null,"dependencies":null,"market_price":0.5,"origin_type":"internal","origin_url":null,"lifecycle_changed_at":"2026-04-02T13:40:08-07:00","citation_count":0,"embed_count":0,"derivation_count":0,"support_count":0,"contradiction_count":0,"total_usage":0.0,"usage_score":0.5,"usage_computed_at":null,"quality_status":"ok","contributors":[],"answers_question_ids":null,"deprecated_reason_detail":null,"deprecated_reason_code":null,"commit_sha":null,"commit_submodule":null,"last_mutated_at":"2026-05-16T14:51:34.657673-07:00","disputed_at":null,"gap_id":null,"mission_id":null,"intrinsic_priority":null,"effective_priority":null,"artifact_id":"54340573-8915-480b-987e-5beb6b658f51","artifact_dir":null,"primary_filename":null,"accessory_filenames":null,"folder_layout_version":1,"migrated_to_folder_at":null,"hypothesis_id":null,"authorship":{"kind":"human","contributors":[{"role":"author","actor_ref":"crosslink-migration"}]},"epistemic_tier":"T3_provisional","created_by_agent_id":null},"outgoing_links":[{"target_artifact_id":"experiment-exp-36adfa0c-75e6-4898-b4fd-ab95fa7beea6","link_type":"mentions","strength":0.8,"evidence":"Gene target: CHAT"},{"target_artifact_id":"experiment-exp-660b0861-aba0-4355-aa4f-e811f4a549c4","link_type":"mentions","strength":0.8,"evidence":"Gene target: CHAT"},{"target_artifact_id":"hypothesis-h-ac55ff26","link_type":"mentions","strength":0.5,"evidence":"Wiki page title/slug matches hypothesis keyword 'Gene'"},{"target_artifact_id":"hypothesis-h-2600483e","link_type":"mentions","strength":0.5,"evidence":"Wiki page title/slug matches hypothesis keyword 'Gene'"},{"target_artifact_id":"analysis-SDA-2026-04-02-26abc5e5f9f2","link_type":"mentions","strength":0.4,"evidence":"Wiki page matches analysis keyword 'genes'"},{"target_artifact_id":"hypothesis-h-c8ccbee8","link_type":"mentions","strength":0.5,"evidence":"Entity 'CHAT' mentioned in hypothesis description/evidence"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-005","link_type":"mentions","strength":0.35,"evidence":"Via hypothesis description entity 'CHAT'"},{"target_artifact_id":"hypothesis-h-05b8894a","link_type":"mentions","strength":0.5,"evidence":"Entity 'CHAT' mentioned in hypothesis description/evidence"},{"target_artifact_id":"hypothesis-h-a1b56d74","link_type":"mentions","strength":0.5,"evidence":"Entity 'CHAT' mentioned in hypothesis description/evidence"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-007","link_type":"mentions","strength":0.35,"evidence":"Via hypothesis description entity 'CHAT'"},{"target_artifact_id":"hypothesis-h-807d7a82","link_type":"mentions","strength":0.5,"evidence":"Entity 'CHAT' mentioned in hypothesis description/evidence"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-013","link_type":"mentions","strength":0.35,"evidence":"Via hypothesis description entity 'CHAT'"},{"target_artifact_id":"hypothesis-h-8196b893","link_type":"mentions","strength":0.5,"evidence":"Entity 'CHAT' mentioned in hypothesis description/evidence"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-v2-68d9c9c1","link_type":"mentions","strength":0.35,"evidence":"Via hypothesis description entity 'CHAT'"},{"target_artifact_id":"hypothesis-h-98b431ba","link_type":"mentions","strength":0.5,"evidence":"Entity 'CHAT' mentioned in hypothesis description/evidence"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-v2-89432b95","link_type":"mentions","strength":0.35,"evidence":"Via hypothesis description entity 'CHAT'"},{"target_artifact_id":"hypothesis-h-346639e8","link_type":"mentions","strength":0.5,"evidence":"Entity 'CHAT' mentioned in hypothesis description/evidence"},{"target_artifact_id":"hypothesis-h-782e55f6","link_type":"mentions","strength":0.5,"evidence":"Entity 'CHAT' mentioned in hypothesis description/evidence"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-v2-bc5f270e","link_type":"mentions","strength":0.35,"evidence":"Via hypothesis description entity 'CHAT'"},{"target_artifact_id":"hypothesis-h-8d270062","link_type":"mentions","strength":0.5,"evidence":"Entity 'CHAT' mentioned in hypothesis description/evidence"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-v2-18cf98ca","link_type":"mentions","strength":0.35,"evidence":"Via hypothesis description entity 'CHAT'"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-005","link_type":"related","strength":0.5,"evidence":"Auto: transitive via hypothesis"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-lipid-rafts-2026-04-01","link_type":"related","strength":0.5,"evidence":"Auto: transitive via hypothesis"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-v2-89432b95","link_type":"related","strength":0.5,"evidence":"Auto: transitive via hypothesis"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-v2-bc5f270e","link_type":"related","strength":0.5,"evidence":"Auto: transitive via hypothesis"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-013","link_type":"related","strength":0.5,"evidence":"Auto: transitive via hypothesis"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-v2-68d9c9c1","link_type":"related","strength":0.5,"evidence":"Auto: transitive via hypothesis"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-v2-18cf98ca","link_type":"related","strength":0.5,"evidence":"Auto: transitive via hypothesis"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-007","link_type":"related","strength":0.5,"evidence":"Auto: transitive via hypothesis"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-014","link_type":"related","strength":0.5,"evidence":"Auto: transitive via hypothesis"},{"target_artifact_id":"hypothesis-h-49791706","link_type":"mentions","strength":0.5,"evidence":"KG transitive via GABRA1"},{"target_artifact_id":"hypothesis-h-44195347","link_type":"mentions","strength":0.5,"evidence":"KG transitive via APOE"},{"target_artifact_id":"hypothesis-h-d0a564e8","link_type":"mentions","strength":0.5,"evidence":"KG transitive via APOE"},{"target_artifact_id":"hypothesis-h-11795af0","link_type":"mentions","strength":0.5,"evidence":"KG transitive via APOE"},{"target_artifact_id":"hypothesis-h-99b4e2d2","link_type":"mentions","strength":0.5,"evidence":"KG transitive via APOE"},{"target_artifact_id":"hypothesis-h-a20e0cbb","link_type":"mentions","strength":0.5,"evidence":"KG transitive via APOE"},{"target_artifact_id":"hypothesis-h-seaad-fa5ea82d","link_type":"mentions","strength":0.5,"evidence":"KG transitive via APOE"},{"target_artifact_id":"hypothesis-h-4113b0e8","link_type":"mentions","strength":0.5,"evidence":"KG transitive via ADRA2A"},{"target_artifact_id":"hypothesis-h-856feb98","link_type":"mentions","strength":0.5,"evidence":"KG transitive via BDNF"},{"target_artifact_id":"hypothesis-h-4bb7fd8c","link_type":"mentions","strength":0.5,"evidence":"KG transitive via SIRT1"},{"target_artifact_id":"hypothesis-h-seaad-56fa6428","link_type":"mentions","strength":0.5,"evidence":"KG transitive via GFAP"},{"target_artifact_id":"hypothesis-h-63b7bacd","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'CHAT Gene' — entity matches hypothesis target"},{"target_artifact_id":"hypothesis-h-9d22b570","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'CHAT Gene' — entity matches hypothesis target"},{"target_artifact_id":"hypothesis-h-24e08335","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'CHAT Gene' — entity matches hypothesis target"},{"target_artifact_id":"wiki-genes-abcg2","link_type":"see_also","strength":0.6,"evidence":"KG edge: associated_with"},{"target_artifact_id":"wiki-genes-ace","link_type":"see_also","strength":0.6,"evidence":"KG edge: therapeutic_target"},{"target_artifact_id":"wiki-genes-adrb2","link_type":"see_also","strength":0.6,"evidence":"KG edge: associated_with"},{"target_artifact_id":"wiki-genes-abcb1","link_type":"see_also","strength":0.6,"evidence":"KG edge: associated_with"},{"target_artifact_id":"wiki-entities-acetylcholine","link_type":"see_also","strength":0.6,"evidence":"KG edge: co_discussed"},{"target_artifact_id":"wiki-genes-adra2a","link_type":"see_also","strength":0.6,"evidence":"KG edge: associated_with"},{"target_artifact_id":"wiki-institutions-alzheimer-indonesia","link_type":"see_also","strength":0.6,"evidence":"KG edge: activates"},{"target_artifact_id":"analysis-SDA-2026-04-02-gap-crispr-neurodegeneration-20260402","link_type":"mentions","strength":0.35,"evidence":"Via hypothesis description entity 'CHAT'"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-20260401-225149","link_type":"mentions","strength":0.35,"evidence":"Via hypothesis description entity 'CHAT'"},{"target_artifact_id":"hypothesis-h-a4e259e0","link_type":"mentions","strength":0.65,"evidence":"Wiki page content mentions hypothesis target gene: CHRNA7"},{"target_artifact_id":"analysis-SDA-2026-04-02-gap-epigenetic-reprog-b685190e","link_type":"related","strength":0.5,"evidence":"{\"via\":\"hypothesis_parent\"}"},{"target_artifact_id":"hypothesis-h-4113b0e8","link_type":"related","strength":0.55,"evidence":"Shared KG edge: ADRA2A → CHAT"},{"target_artifact_id":"analysis-SDA-2026-04-03-26abc5e5f9f2","link_type":"related","strength":0.4,"evidence":"KG edge: CAMK2A --[co_associated_with]--> CHAT"},{"target_artifact_id":"analysis-SDA-2026-04-03-26abc5e5f9f2","link_type":"related","strength":0.7,"evidence":"Analysis investigates gene: CHAT"},{"target_artifact_id":"analysis-SDA-2026-04-12-20260411-082446-2c1c9e2d","link_type":"related","strength":0.7,"evidence":"Analysis investigates gene: CHAT"}],"incoming_links":[{"source_artifact_id":"experiment-exp-36adfa0c-75e6-4898-b4fd-ab95fa7beea6","link_type":"related","strength":0.3333333333333333,"evidence":null},{"source_artifact_id":"hypothesis-h-a4e259e0","link_type":"related","strength":0.5850000000000001,"evidence":"Reverse: Wiki page content mentions hypothesis target gene: CHRNA7"},{"source_artifact_id":"experiment-exp-660b0861-aba0-4355-aa4f-e811f4a549c4","link_type":"related","strength":0.7200000000000001,"evidence":"Reverse: Gene target: CHAT"},{"source_artifact_id":"hypothesis-h-ac55ff26","link_type":"related","strength":0.4,"evidence":"Auto: reverse of wiki→hypothesis"},{"source_artifact_id":"hypothesis-h-2600483e","link_type":"related","strength":0.4,"evidence":"Auto: reverse of wiki→hypothesis"},{"source_artifact_id":"hypothesis-h-c8ccbee8","link_type":"related","strength":0.4,"evidence":"Auto: reverse of wiki→hypothesis"},{"source_artifact_id":"hypothesis-h-05b8894a","link_type":"related","strength":0.4,"evidence":"Auto: reverse of wiki→hypothesis"},{"source_artifact_id":"hypothesis-h-a1b56d74","link_type":"related","strength":0.4,"evidence":"Auto: reverse of wiki→hypothesis"},{"source_artifact_id":"hypothesis-h-807d7a82","link_type":"related","strength":0.4,"evidence":"Auto: reverse of wiki→hypothesis"},{"source_artifact_id":"hypothesis-h-8196b893","link_type":"related","strength":0.4,"evidence":"Auto: reverse of wiki→hypothesis"},{"source_artifact_id":"hypothesis-h-98b431ba","link_type":"related","strength":0.4,"evidence":"Auto: reverse of wiki→hypothesis"},{"source_artifact_id":"hypothesis-h-346639e8","link_type":"related","strength":0.4,"evidence":"Auto: reverse of wiki→hypothesis"},{"source_artifact_id":"hypothesis-h-782e55f6","link_type":"related","strength":0.4,"evidence":"Auto: reverse of wiki→hypothesis"},{"source_artifact_id":"hypothesis-h-8d270062","link_type":"related","strength":0.4,"evidence":"Auto: reverse of wiki→hypothesis"},{"source_artifact_id":"wiki-genes-oprm1","link_type":"see_also","strength":0.6,"evidence":"KG edge: associated_with"},{"source_artifact_id":"wiki-genes-slc30a8","link_type":"see_also","strength":0.6,"evidence":"KG edge: associated_with"},{"source_artifact_id":"wiki-genes-dpm2","link_type":"see_also","strength":0.6,"evidence":"KG edge: associated_with"},{"source_artifact_id":"wiki-genes-nbea","link_type":"see_also","strength":0.6,"evidence":"KG edge: associated_with"},{"source_artifact_id":"wiki-genes-slc22a1","link_type":"see_also","strength":0.6,"evidence":"KG edge: transports"},{"source_artifact_id":"wiki-genes-sox10","link_type":"see_also","strength":0.6,"evidence":"KG edge: activates"},{"source_artifact_id":"wiki-entities-acetylcholine","link_type":"see_also","strength":0.6,"evidence":"KG edge: interacts_with"},{"source_artifact_id":"wiki-proteins-oprm1","link_type":"see_also","strength":0.6,"evidence":"KG edge: associated_with"},{"source_artifact_id":"wiki-proteins-gstp1","link_type":"see_also","strength":0.6,"evidence":"KG edge: associated_with"},{"source_artifact_id":"wiki-genes-htr2c","link_type":"see_also","strength":0.6,"evidence":"KG edge: associated_with"},{"source_artifact_id":"wiki-genes-rab5a","link_type":"see_also","strength":0.6,"evidence":"KG edge: interacts_with"},{"source_artifact_id":"wiki-genes-gstp1","link_type":"see_also","strength":0.6,"evidence":"KG edge: associated_with"},{"source_artifact_id":"hypothesis-h-9d22b570","link_type":"mentions","strength":0.5,"evidence":"Entity CHAT in hypothesis text"},{"source_artifact_id":"analysis-SDA-2026-04-01-gap-005","link_type":"related","strength":0.5,"evidence":"Reverse link"},{"source_artifact_id":"analysis-SDA-2026-04-01-gap-007","link_type":"related","strength":0.5,"evidence":"Reverse link"},{"source_artifact_id":"analysis-SDA-2026-04-01-gap-013","link_type":"related","strength":0.5,"evidence":"Reverse link"},{"source_artifact_id":"analysis-SDA-2026-04-01-gap-014","link_type":"related","strength":0.5,"evidence":"Reverse link"},{"source_artifact_id":"analysis-SDA-2026-04-01-gap-20260401-225149","link_type":"related","strength":0.5,"evidence":"Reverse link"},{"source_artifact_id":"analysis-SDA-2026-04-01-gap-lipid-rafts-2026-04-01","link_type":"related","strength":0.5,"evidence":"Reverse link"},{"source_artifact_id":"analysis-SDA-2026-04-01-gap-v2-18cf98ca","link_type":"related","strength":0.5,"evidence":"Reverse link"},{"source_artifact_id":"analysis-SDA-2026-04-01-gap-v2-68d9c9c1","link_type":"related","strength":0.5,"evidence":"Reverse link"},{"source_artifact_id":"analysis-SDA-2026-04-01-gap-v2-89432b95","link_type":"related","strength":0.5,"evidence":"Reverse link"},{"source_artifact_id":"analysis-SDA-2026-04-01-gap-v2-bc5f270e","link_type":"related","strength":0.5,"evidence":"Reverse link"},{"source_artifact_id":"analysis-SDA-2026-04-02-26abc5e5f9f2","link_type":"related","strength":0.5,"evidence":"Reverse link"},{"source_artifact_id":"analysis-SDA-2026-04-02-gap-crispr-neurodegeneration-20260402","link_type":"related","strength":0.5,"evidence":"Reverse link"}],"current_artifact_id":"wiki-genes-chat","is_canonical":true,"supersede_chain":["wiki-genes-chat"]}