{"artifact":{"id":"wiki-genes-gpx4","artifact_type":"wiki_page","entity_ids":"[\"GPX4\"]","title":"GPX4 Gene - Glutathione Peroxidase 4","quality_score":0.5,"created_by":"crosslink-migration","provenance_chain":"[]","content_hash":"8bfde6ddfef5d9355b8983aaf6ccfcca5dd2d68f1f49100225672efafbbca5cf","metadata":{"slug":"genes-gpx4","kg_node_id":"GPX4","entity_type":"gene","origin_type":"v1_polymorphic_backfill","source_table":"wiki_pages","wiki_page_id":"wp-a6a7db9aabe9","__merged_from":{"merged_at":"2026-05-13","unprefixed_id":"genes-gpx4"},"_schema_version":1},"created_at":"2026-04-02T07:19:19-07:00","updated_at":"2026-04-02T13:40:08-07:00","version_number":5,"parent_version_id":null,"version_tag":null,"changelog":null,"is_latest":1,"lifecycle_state":"active","superseded_by":null,"deprecated_at":null,"deprecated_reason":null,"dependencies":null,"market_price":0.5,"origin_type":"internal","origin_url":null,"lifecycle_changed_at":"2026-04-02T13:40:08-07:00","citation_count":0,"embed_count":0,"derivation_count":0,"support_count":0,"contradiction_count":0,"total_usage":0.0,"usage_score":0.5,"usage_computed_at":null,"quality_status":"ok","contributors":[],"answers_question_ids":null,"deprecated_reason_detail":null,"deprecated_reason_code":null,"commit_sha":null,"commit_submodule":null,"last_mutated_at":"2026-05-16T14:51:34.657673-07:00","disputed_at":null,"gap_id":null,"mission_id":null,"intrinsic_priority":null,"effective_priority":null,"artifact_id":"3f993da6-5cfd-495d-8bee-d1cc2c0336d0","artifact_dir":null,"primary_filename":null,"accessory_filenames":null,"folder_layout_version":1,"migrated_to_folder_at":null,"hypothesis_id":null,"authorship":{"kind":"human","contributors":[{"role":"author","actor_ref":"crosslink-migration"}]},"epistemic_tier":"T3_provisional","created_by_agent_id":null},"outgoing_links":[{"target_artifact_id":"analysis-SDA-2026-04-03-gap-aging-mouse-brain-v3-20260402","link_type":"related","strength":0.4,"evidence":"KG edge: ACE --[co_associated_with]--> GPX4"},{"target_artifact_id":"analysis-SDA-2026-04-03-gap-seaad-v4-20260402065846","link_type":"related","strength":0.4,"evidence":"KG edge: ACSL4 --[co_discussed]--> GPX4"},{"target_artifact_id":"analysis-sda-2026-04-01-gap-013","link_type":"related","strength":0.4,"evidence":"KG edge: AQP4 --[co_discussed]--> GPX4"},{"target_artifact_id":"analysis-sda-2026-04-01-gap-v2-89432b95","link_type":"related","strength":0.4,"evidence":"KG edge: GPX4 --[co_discussed]--> PARKIN"},{"target_artifact_id":"experiment-exp-9f358501-0c3d-417e-9b43-1be792ee3638","link_type":"mentions","strength":0.8,"evidence":"Gene target: GPX4"},{"target_artifact_id":"experiment-exp-5266cad2-5537-4d55-9c18-5bb31ca03fb2","link_type":"mentions","strength":0.7,"evidence":"Gene mention: GPX4"},{"target_artifact_id":"experiment-exp-46757fd6-b353-4551-b105-757ecff66ef9","link_type":"mentions","strength":0.7,"evidence":"Gene mention: GPX4"},{"target_artifact_id":"analysis-SDA-2026-04-15-gap-debate-20260410-112528-782f5aa2","link_type":"mentions","strength":0.5,"evidence":"Entity GPX4 in analysis"},{"target_artifact_id":"hypothesis-h-7957bb2a","link_type":"mentions","strength":0.9,"evidence":"Entity 'GPX4' links wiki 'GPX4 Gene - Glutathione Peroxidase 4' to hypothesis"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-013","link_type":"mentions","strength":0.63,"evidence":"Via hypothesis entity 'GPX4'"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-013","link_type":"related","strength":0.4,"evidence":"KG edge: AQP4 --[co_discussed]--> GPX4"},{"target_artifact_id":"hypothesis-h-ac55ff26","link_type":"mentions","strength":0.5,"evidence":"Wiki page title/slug matches hypothesis keyword 'Gene'"},{"target_artifact_id":"hypothesis-h-2600483e","link_type":"mentions","strength":0.5,"evidence":"Wiki page title/slug matches hypothesis keyword 'Gene'"},{"target_artifact_id":"analysis-SDA-2026-04-02-26abc5e5f9f2","link_type":"mentions","strength":0.4,"evidence":"Wiki page matches analysis keyword 'genes'"},{"target_artifact_id":"hypothesis-h-fd1562a3","link_type":"related","strength":0.4,"evidence":null},{"target_artifact_id":"hypothesis-h-98b431ba","link_type":"related","strength":0.4,"evidence":null},{"target_artifact_id":"hypothesis-h-cb833ed8","link_type":"related","strength":0.4,"evidence":null},{"target_artifact_id":"hypothesis-h-250b34ab","link_type":"related","strength":0.4,"evidence":null},{"target_artifact_id":"hypothesis-h-6ce4884a","link_type":"related","strength":0.4,"evidence":null},{"target_artifact_id":"hypothesis-h-346639e8","link_type":"related","strength":0.4,"evidence":null},{"target_artifact_id":"hypothesis-h-13ef5927","link_type":"related","strength":0.4,"evidence":null},{"target_artifact_id":"hypothesis-h-1a34778f","link_type":"related","strength":0.4,"evidence":null},{"target_artifact_id":"experiment-exp-wiki-experiments-peroxisome-dysfunction-parkinsons","link_type":"mentions","strength":0.7,"evidence":"Gene match: GPX4"},{"target_artifact_id":"hypothesis-h-43f72e21","link_type":"related","strength":0.4,"evidence":null},{"target_artifact_id":"hypothesis-h-58e4635a","link_type":"related","strength":0.4,"evidence":null},{"target_artifact_id":"hypothesis-h-807d7a82","link_type":"related","strength":0.4,"evidence":null},{"target_artifact_id":"hypothesis-h-1acdd55e","link_type":"related","strength":0.4,"evidence":null},{"target_artifact_id":"hypothesis-h-bb518928","link_type":"related","strength":0.4,"evidence":null},{"target_artifact_id":"hypothesis-h-57862f8a","link_type":"mentions","strength":0.5,"evidence":"Entity 'GPX4' mentioned in hypothesis description/evidence"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-004","link_type":"mentions","strength":0.35,"evidence":"Via hypothesis description entity 'GPX4'"},{"target_artifact_id":"hypothesis-h-aa8b4952","link_type":"mentions","strength":0.5,"evidence":"Entity 'GPX4' mentioned in hypothesis description/evidence"},{"target_artifact_id":"hypothesis-h-aa2d317c","link_type":"mentions","strength":0.5,"evidence":"Entity 'GPX4' mentioned in hypothesis description/evidence"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-008","link_type":"mentions","strength":0.35,"evidence":"Via hypothesis description entity 'GPX4'"},{"target_artifact_id":"hypothesis-h-b0cda336","link_type":"mentions","strength":0.5,"evidence":"Entity 'GPX4' mentioned in hypothesis description/evidence"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-012","link_type":"mentions","strength":0.35,"evidence":"Via hypothesis description entity 'GPX4'"},{"target_artifact_id":"hypothesis-h-959a4677","link_type":"mentions","strength":0.5,"evidence":"Entity 'GPX4' mentioned in hypothesis description/evidence"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-014","link_type":"mentions","strength":0.35,"evidence":"Via hypothesis description entity 'GPX4'"},{"target_artifact_id":"hypothesis-h-82922df8","link_type":"mentions","strength":0.5,"evidence":"Entity 'GPX4' mentioned in hypothesis description/evidence"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-v2-ee5a5023","link_type":"mentions","strength":0.35,"evidence":"Via hypothesis description entity 'GPX4'"},{"target_artifact_id":"hypothesis-h-43f72e21","link_type":"mentions","strength":0.5,"evidence":"Entity 'GPX4' mentioned in hypothesis description/evidence"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-v2-89432b95","link_type":"mentions","strength":0.35,"evidence":"Via hypothesis description entity 'GPX4'"},{"target_artifact_id":"hypothesis-h-98b431ba","link_type":"mentions","strength":0.5,"evidence":"Entity 'GPX4' mentioned in hypothesis description/evidence"},{"target_artifact_id":"hypothesis-h-a9571dbb","link_type":"mentions","strength":0.5,"evidence":"Entity 'GPX4' mentioned in hypothesis description/evidence"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-v2-bc5f270e","link_type":"mentions","strength":0.35,"evidence":"Via hypothesis description entity 'GPX4'"},{"target_artifact_id":"hypothesis-h-0e675a41","link_type":"mentions","strength":0.5,"evidence":"Entity 'GPX4' mentioned in hypothesis description/evidence"},{"target_artifact_id":"analysis-SDA-2026-04-02-gap-epigenetic-reprog-b685190e","link_type":"mentions","strength":0.35,"evidence":"Via hypothesis description entity 'GPX4'"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-v2-89432b95","link_type":"related","strength":0.4,"evidence":"KG edge: GPX4 --[co_discussed]--> PARKIN"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-004","link_type":"related","strength":0.5,"evidence":"Auto: transitive via hypothesis"},{"target_artifact_id":"analysis-SDA-2026-04-02-gap-epigenetic-reprog-b685190e","link_type":"related","strength":0.5,"evidence":"Auto: transitive via hypothesis"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-lipid-rafts-2026-04-01","link_type":"related","strength":0.5,"evidence":"Auto: transitive via hypothesis"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-20260401-225149","link_type":"related","strength":0.5,"evidence":"Auto: transitive via hypothesis"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-v2-ee5a5023","link_type":"related","strength":0.5,"evidence":"Auto: transitive via hypothesis"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-014","link_type":"related","strength":0.5,"evidence":"Auto: transitive via hypothesis"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-v2-bc5f270e","link_type":"related","strength":0.5,"evidence":"Auto: transitive via hypothesis"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-008","link_type":"related","strength":0.5,"evidence":"Auto: transitive via hypothesis"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-012","link_type":"related","strength":0.5,"evidence":"Auto: transitive via hypothesis"},{"target_artifact_id":"hypothesis-h-7bb47d7a","link_type":"mentions","strength":0.9,"evidence":"Wiki page mentions gene TH targeted by hypothesis"},{"target_artifact_id":"experiment-exp-wiki-experiments-oligodendrocyte-myelin-dysfunction-parkinsons","link_type":"related","strength":0.7,"evidence":"Wiki page for ID related to experiment"},{"target_artifact_id":"experiment-exp-wiki-experiments-neural-oscillation-dysfunction-parkinsons","link_type":"related","strength":0.7,"evidence":"Wiki page for ID related to experiment"},{"target_artifact_id":"experiment-exp-wiki-experiments-proteasome-ubiquitin-system-dysfunction-parkinso","link_type":"related","strength":0.7,"evidence":"Wiki page for ID related to experiment"},{"target_artifact_id":"experiment-exp-wiki-experiments-microbiome-alpha-synuclein-propagation","link_type":"related","strength":0.7,"evidence":"Wiki page for ID related to experiment"},{"target_artifact_id":"experiment-exp-wiki-experiments-stress-granule-dysfunction-parkinsons","link_type":"related","strength":0.7,"evidence":"Wiki page for ID related to experiment"},{"target_artifact_id":"experiment-exp-wiki-experiments-animal-model-comparison-neurodegeneration","link_type":"related","strength":0.7,"evidence":"Wiki page for ID related to experiment"},{"target_artifact_id":"experiment-exp-wiki-experiments-protein-aggregation-kinetic-validation","link_type":"related","strength":0.7,"evidence":"Wiki page for ID related to experiment"},{"target_artifact_id":"experiment-exp-wiki-experiments-tht-validation-protein-aggregation","link_type":"related","strength":0.7,"evidence":"Wiki page for ID related to experiment"},{"target_artifact_id":"experiment-exp-wiki-experiments-endocannabinoid-system-dysfunction-parkinsons","link_type":"related","strength":0.7,"evidence":"Wiki page for ID related to experiment"},{"target_artifact_id":"experiment-exp-wiki-experiments-glymphatic-circadian-axis-parkinsons","link_type":"related","strength":0.7,"evidence":"Wiki page for ID related to experiment"},{"target_artifact_id":"experiment-exp-wiki-experiments-er-golgi-secretory-pathway-parkinsons","link_type":"related","strength":0.7,"evidence":"Wiki page for ER related to experiment"},{"target_artifact_id":"experiment-exp-wiki-experiments-peroxisome-dysfunction-parkinsons","link_type":"related","strength":0.7,"evidence":"Wiki page for GPX4 related to experiment"},{"target_artifact_id":"experiment-exp-wiki-experiments-regulated-necrosis-parkinsons","link_type":"related","strength":0.7,"evidence":"Wiki page for ID related to experiment"},{"target_artifact_id":"experiment-exp-wiki-experiments-purinergic-signaling-parkinsons","link_type":"related","strength":0.7,"evidence":"Wiki page for ID related to experiment"},{"target_artifact_id":"hypothesis-h-856feb98","link_type":"mentions","strength":0.5,"evidence":"KG transitive via BDNF"},{"target_artifact_id":"hypothesis-h-seaad-v4-26ba859b","link_type":"related","strength":0.4,"evidence":null},{"target_artifact_id":"hypothesis-h-c8ccbee8","link_type":"mentions","strength":0.5,"evidence":"KG transitive via AQP4"},{"target_artifact_id":"hypothesis-h-62e56eb9","link_type":"mentions","strength":0.5,"evidence":"KG transitive via AQP4"},{"target_artifact_id":"analysis-SDA-2026-04-02-gap-seaad-v4-20260402065846","link_type":"mentions","strength":0.5,"evidence":null},{"target_artifact_id":"hypothesis-h-seaad-v4-5a7a4079","link_type":"related","strength":0.4,"evidence":null},{"target_artifact_id":"hypothesis-h-seaad-v4-29e81bbc","link_type":"related","strength":0.4,"evidence":null},{"target_artifact_id":"hypothesis-h-76888762","link_type":"mentions","strength":0.5,"evidence":"KG transitive via PPARGC1A"},{"target_artifact_id":"hypothesis-h-5dbfd3aa","link_type":"mentions","strength":0.5,"evidence":"KG transitive via HSPA1A"},{"target_artifact_id":"hypothesis-h-a1b56d74","link_type":"mentions","strength":0.5,"evidence":"KG transitive via HK2"},{"target_artifact_id":"hypothesis-h-38292315","link_type":"mentions","strength":0.5,"evidence":"KG transitive via HK2"},{"target_artifact_id":"hypothesis-h-5706bbd7","link_type":"mentions","strength":0.5,"evidence":"KG transitive via BMAL1"},{"target_artifact_id":"hypothesis-h-725c62e9","link_type":"mentions","strength":0.5,"evidence":"KG transitive via PIEZO1"},{"target_artifact_id":"hypothesis-h-44195347","link_type":"mentions","strength":0.5,"evidence":"KG transitive via APOE"},{"target_artifact_id":"hypothesis-h-d0a564e8","link_type":"mentions","strength":0.5,"evidence":"KG transitive via APOE"},{"target_artifact_id":"hypothesis-h-11795af0","link_type":"mentions","strength":0.5,"evidence":"KG transitive via APOE"},{"target_artifact_id":"hypothesis-h-99b4e2d2","link_type":"mentions","strength":0.5,"evidence":"KG transitive via APOE"},{"target_artifact_id":"hypothesis-h-a20e0cbb","link_type":"mentions","strength":0.5,"evidence":"KG transitive via APOE"},{"target_artifact_id":"hypothesis-h-seaad-fa5ea82d","link_type":"mentions","strength":0.5,"evidence":"KG transitive via APOE"},{"target_artifact_id":"hypothesis-h-ae1b2beb","link_type":"mentions","strength":0.5,"evidence":"KG transitive via FOXO1"},{"target_artifact_id":"hypothesis-h-83efeed6","link_type":"mentions","strength":0.5,"evidence":"KG transitive via ALOX12"},{"target_artifact_id":"hypothesis-h-ba3a948a","link_type":"mentions","strength":0.5,"evidence":"KG transitive via CX3CR1"},{"target_artifact_id":"hypothesis-h-782b40b1","link_type":"mentions","strength":0.5,"evidence":"KG transitive via CX3CR1"},{"target_artifact_id":"hypothesis-h-044ee057","link_type":"mentions","strength":0.5,"evidence":"KG transitive via TREM2"},{"target_artifact_id":"hypothesis-h-b234254c","link_type":"mentions","strength":0.5,"evidence":"KG transitive via TREM2"},{"target_artifact_id":"hypothesis-h-seaad-51323624","link_type":"mentions","strength":0.5,"evidence":"KG transitive via TREM2"},{"target_artifact_id":"hypothesis-h-782e55f6","link_type":"mentions","strength":0.5,"evidence":"KG transitive via DNMT1"},{"target_artifact_id":"hypothesis-h-4dd0d19b","link_type":"mentions","strength":0.5,"evidence":"KG transitive via LRP1"},{"target_artifact_id":"hypothesis-h-55ef81c5","link_type":"mentions","strength":0.5,"evidence":"KG transitive via CHMP4B"},{"target_artifact_id":"hypothesis-h-0f00fd75","link_type":"mentions","strength":0.5,"evidence":"KG transitive via HSP90AA1"},{"target_artifact_id":"hypothesis-h-4bb7fd8c","link_type":"mentions","strength":0.5,"evidence":"KG transitive via SIRT1"},{"target_artifact_id":"hypothesis-h-0e614ae4","link_type":"mentions","strength":0.5,"evidence":"KG transitive via SIRT3"},{"target_artifact_id":"hypothesis-h-seaad-56fa6428","link_type":"mentions","strength":0.5,"evidence":"KG transitive via GFAP"},{"target_artifact_id":"hypothesis-h-seaad-v4-26ba859b","link_type":"mentions","strength":0.5,"evidence":"Wiki page 'GPX4 Gene - Glutathione Peroxidase 4' — entity matches hypothesis target"},{"target_artifact_id":"wiki-genes-acsl4","link_type":"see_also","strength":0.6,"evidence":"KG edge: activates"},{"target_artifact_id":"wiki-genes-actb","link_type":"see_also","strength":0.6,"evidence":"KG edge: associated_with"},{"target_artifact_id":"wiki-genes-aif","link_type":"see_also","strength":0.6,"evidence":"KG edge: regulates"},{"target_artifact_id":"wiki-mechanisms-aging-vs-neurodegeneration-comparison","link_type":"see_also","strength":0.6,"evidence":"KG edge: activates"},{"target_artifact_id":"experiment-exp-wiki-experiments-ferroptosis-parkinsons","link_type":"mentions","strength":0.5,"evidence":"Entity GPX4 in experiment"},{"target_artifact_id":"notebook-h-seaad-v4-26ba859b","link_type":"mentions","strength":0.7,"evidence":"Shared entity 'GPX4'"},{"target_artifact_id":"hypothesis-h-8196b893","link_type":"mentions","strength":0.5,"evidence":"Entity 'GPX4' mentioned in hypothesis description/evidence"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-v2-68d9c9c1","link_type":"mentions","strength":0.35,"evidence":"Via hypothesis description entity 'GPX4'"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-011","link_type":"related","strength":0.5,"evidence":"{\"via\":\"hypothesis_parent\"}"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-010","link_type":"related","strength":0.5,"evidence":"{\"via\":\"hypothesis_parent\"}"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-v2-691b42f1","link_type":"related","strength":0.5,"evidence":"{\"via\":\"hypothesis_parent\"}"},{"target_artifact_id":"hypothesis-h-83efeed6","link_type":"related","strength":0.55,"evidence":"Shared KG edge: ALOX12 → GPX4"},{"target_artifact_id":"hypothesis-h-ac55ff26","link_type":"related","strength":0.55,"evidence":"Shared KG edge: ALOX15 → GPX4"},{"target_artifact_id":"experiment-exp-debate-e026e4a2e7eb","link_type":"related","strength":0.5,"evidence":"Experiment from analysis studying entity in wiki page"},{"target_artifact_id":"analysis-SDA-2026-04-03-gap-aging-mouse-brain-20260402","link_type":"related","strength":0.4,"evidence":"KG edge: ACE --[co_associated_with]--> GPX4"},{"target_artifact_id":"analysis-SDA-2026-04-02-gap-seaad-v4-20260402065846","link_type":"related","strength":0.4,"evidence":"KG edge: ACSL4 --[co_discussed]--> GPX4"},{"target_artifact_id":"analysis-SDA-2026-04-03-gap-aging-mouse-brain-v3-20260402","link_type":"related","strength":0.7,"evidence":"Analysis investigates gene: GPX4"}],"incoming_links":[{"source_artifact_id":"experiment-exp-5266cad2-5537-4d55-9c18-5bb31ca03fb2","link_type":"related","strength":0.25,"evidence":null},{"source_artifact_id":"experiment-exp-9f358501-0c3d-417e-9b43-1be792ee3638","link_type":"related","strength":0.7200000000000001,"evidence":"Reverse: Gene target: GPX4"},{"source_artifact_id":"experiment-exp-46757fd6-b353-4551-b105-757ecff66ef9","link_type":"related","strength":0.63,"evidence":"Reverse: Gene mention: GPX4"},{"source_artifact_id":"analysis-SDA-2026-04-15-gap-debate-20260410-112528-782f5aa2","link_type":"mentions","strength":0.5,"evidence":"Entity GPX4 in analysis"},{"source_artifact_id":"experiment-exp-5266cad2-5537-4d55-9c18-5bb31ca03fb2","link_type":"mentions","strength":0.5,"evidence":"Entity GPX4 in experiment"},{"source_artifact_id":"experiment-exp-46757fd6-b353-4551-b105-757ecff66ef9","link_type":"mentions","strength":0.5,"evidence":"Entity GPX4 in experiment"},{"source_artifact_id":"hypothesis-h-7957bb2a","link_type":"mentions","strength":0.8,"evidence":"Hypothesis targets gene GPX4"},{"source_artifact_id":"analysis-SDA-2026-04-01-gap-013","link_type":"mentions","strength":0.7,"evidence":"Analysis produced hypotheses targeting GPX4"},{"source_artifact_id":"hypothesis-h-7957bb2a","link_type":"related","strength":0.9,"evidence":"Hypothesis targets gene GPX4 described in wiki"},{"source_artifact_id":"analysis-SDA-2026-04-01-gap-013","link_type":"related","strength":0.5670000000000001,"evidence":"Reverse: Via hypothesis entity 'GPX4'"},{"source_artifact_id":"experiment-exp-wiki-experiments-peroxisome-dysfunction-parkinsons","link_type":"related","strength":0.63,"evidence":"Reverse: Gene match: GPX4"},{"source_artifact_id":"hypothesis-h-7bb47d7a","link_type":"related","strength":0.9,"evidence":"Hypothesis targets gene TH described in wiki"},{"source_artifact_id":"experiment-exp-wiki-experiments-oligodendrocyte-myelin-dysfunction-parkinsons","link_type":"related","strength":0.7,"evidence":"Experiment targets ID described in wiki"},{"source_artifact_id":"experiment-exp-wiki-experiments-neural-oscillation-dysfunction-parkinsons","link_type":"related","strength":0.7,"evidence":"Experiment targets ID described in wiki"},{"source_artifact_id":"experiment-exp-wiki-experiments-proteasome-ubiquitin-system-dysfunction-parkinso","link_type":"related","strength":0.7,"evidence":"Experiment targets ID described in wiki"},{"source_artifact_id":"experiment-exp-wiki-experiments-microbiome-alpha-synuclein-propagation","link_type":"related","strength":0.7,"evidence":"Experiment targets ID described in wiki"},{"source_artifact_id":"experiment-exp-wiki-experiments-stress-granule-dysfunction-parkinsons","link_type":"related","strength":0.7,"evidence":"Experiment targets ID described in wiki"},{"source_artifact_id":"experiment-exp-wiki-experiments-animal-model-comparison-neurodegeneration","link_type":"related","strength":0.7,"evidence":"Experiment targets ID described in wiki"},{"source_artifact_id":"experiment-exp-wiki-experiments-protein-aggregation-kinetic-validation","link_type":"related","strength":0.7,"evidence":"Experiment targets ID described in wiki"},{"source_artifact_id":"experiment-exp-wiki-experiments-tht-validation-protein-aggregation","link_type":"related","strength":0.7,"evidence":"Experiment targets ID described in wiki"},{"source_artifact_id":"experiment-exp-wiki-experiments-endocannabinoid-system-dysfunction-parkinsons","link_type":"related","strength":0.7,"evidence":"Experiment targets ID described in wiki"},{"source_artifact_id":"experiment-exp-wiki-experiments-glymphatic-circadian-axis-parkinsons","link_type":"related","strength":0.7,"evidence":"Experiment targets ID described in wiki"},{"source_artifact_id":"experiment-exp-wiki-experiments-er-golgi-secretory-pathway-parkinsons","link_type":"related","strength":0.7,"evidence":"Experiment targets ER described in wiki"},{"source_artifact_id":"experiment-exp-wiki-experiments-regulated-necrosis-parkinsons","link_type":"related","strength":0.7,"evidence":"Experiment targets ID described in wiki"},{"source_artifact_id":"experiment-exp-wiki-experiments-purinergic-signaling-parkinsons","link_type":"related","strength":0.7,"evidence":"Experiment targets ID described in wiki"},{"source_artifact_id":"hypothesis-h-ac55ff26","link_type":"related","strength":0.4,"evidence":"Auto: reverse of wiki→hypothesis"},{"source_artifact_id":"hypothesis-h-2600483e","link_type":"related","strength":0.4,"evidence":"Auto: reverse of wiki→hypothesis"},{"source_artifact_id":"hypothesis-h-57862f8a","link_type":"related","strength":0.4,"evidence":"Auto: reverse of wiki→hypothesis"},{"source_artifact_id":"hypothesis-h-aa8b4952","link_type":"related","strength":0.4,"evidence":"Auto: reverse of wiki→hypothesis"},{"source_artifact_id":"hypothesis-h-aa2d317c","link_type":"related","strength":0.4,"evidence":"Auto: reverse of wiki→hypothesis"},{"source_artifact_id":"hypothesis-h-b0cda336","link_type":"related","strength":0.4,"evidence":"Auto: reverse of wiki→hypothesis"},{"source_artifact_id":"hypothesis-h-959a4677","link_type":"related","strength":0.4,"evidence":"Auto: reverse of wiki→hypothesis"},{"source_artifact_id":"hypothesis-h-82922df8","link_type":"related","strength":0.4,"evidence":"Auto: reverse of wiki→hypothesis"},{"source_artifact_id":"hypothesis-h-43f72e21","link_type":"related","strength":0.4,"evidence":"Auto: reverse of wiki→hypothesis"},{"source_artifact_id":"hypothesis-h-98b431ba","link_type":"related","strength":0.4,"evidence":"Auto: reverse of wiki→hypothesis"},{"source_artifact_id":"hypothesis-h-a9571dbb","link_type":"related","strength":0.4,"evidence":"Auto: reverse of wiki→hypothesis"},{"source_artifact_id":"hypothesis-h-0e675a41","link_type":"related","strength":0.4,"evidence":"Auto: reverse of wiki→hypothesis"},{"source_artifact_id":"wiki-companies-dopamine-transporter-modulators","link_type":"see_also","strength":0.6,"evidence":"KG edge: regulates"},{"source_artifact_id":"wiki-mechanisms-demyelination","link_type":"see_also","strength":0.6,"evidence":"KG edge: causes"},{"source_artifact_id":"wiki-genes-stim1","link_type":"see_also","strength":0.6,"evidence":"KG edge: activates"},{"source_artifact_id":"wiki-genes-dnajc12","link_type":"see_also","strength":0.6,"evidence":"KG edge: inhibits"},{"source_artifact_id":"wiki-genes-slc40a1","link_type":"see_also","strength":0.6,"evidence":"KG edge: expressed_in"},{"source_artifact_id":"wiki-genes-otud5","link_type":"see_also","strength":0.6,"evidence":"KG edge: inhibits"},{"source_artifact_id":"wiki-genes-rps21","link_type":"see_also","strength":0.6,"evidence":"KG edge: stabilizes"},{"source_artifact_id":"wiki-genes-zdhhc8","link_type":"see_also","strength":0.6,"evidence":"KG edge: activates"},{"source_artifact_id":"wiki-genes-nqo2","link_type":"see_also","strength":0.6,"evidence":"KG edge: associated_with"},{"source_artifact_id":"wiki-genes-gpt","link_type":"see_also","strength":0.6,"evidence":"KG edge: associated_with"},{"source_artifact_id":"wiki-genes-dnaja1","link_type":"see_also","strength":0.6,"evidence":"KG edge: activates"},{"source_artifact_id":"wiki-genes-got1","link_type":"see_also","strength":0.6,"evidence":"KG edge: activates"},{"source_artifact_id":"wiki-genes-pcbp1","link_type":"see_also","strength":0.6,"evidence":"KG edge: expressed_in"},{"source_artifact_id":"wiki-genes-slc7a1","link_type":"see_also","strength":0.6,"evidence":"KG edge: co_discussed"},{"source_artifact_id":"wiki-genes-klf14","link_type":"see_also","strength":0.6,"evidence":"KG edge: downregulates"},{"source_artifact_id":"wiki-genes-stat4","link_type":"see_also","strength":0.6,"evidence":"KG edge: expressed_in"},{"source_artifact_id":"wiki-ideas-payload-nrf2-activator-therapy","link_type":"see_also","strength":0.6,"evidence":"KG edge: regulates"},{"source_artifact_id":"wiki-entities-glutamate","link_type":"see_also","strength":0.6,"evidence":"KG edge: co_discussed"},{"source_artifact_id":"wiki-mechanisms-chaperone-mediated-autophagy","link_type":"see_also","strength":0.6,"evidence":"KG edge: inhibits"},{"source_artifact_id":"wiki-mechanisms-glutathione-metabolism","link_type":"see_also","strength":0.6,"evidence":"KG edge: activates"},{"source_artifact_id":"wiki-therapeutics-nadph-oxidase-inhibitors","link_type":"see_also","strength":0.6,"evidence":"KG edge: inhibits"},{"source_artifact_id":"wiki-proteins-prdx1","link_type":"see_also","strength":0.6,"evidence":"KG edge: activates"},{"source_artifact_id":"wiki-genes-mmp3","link_type":"see_also","strength":0.6,"evidence":"KG edge: activates"},{"source_artifact_id":"wiki-genes-lgmn","link_type":"see_also","strength":0.6,"evidence":"KG edge: activates"},{"source_artifact_id":"wiki-genes-ireb2","link_type":"see_also","strength":0.6,"evidence":"KG edge: activates"},{"source_artifact_id":"wiki-genes-prmt5","link_type":"see_also","strength":0.6,"evidence":"KG edge: inhibits"},{"source_artifact_id":"wiki-genes-mcu","link_type":"see_also","strength":0.6,"evidence":"KG edge: co_mentioned"},{"source_artifact_id":"wiki-genes-prdx1","link_type":"see_also","strength":0.6,"evidence":"KG edge: activates"},{"source_artifact_id":"wiki-genes-kif4a","link_type":"see_also","strength":0.6,"evidence":"KG edge: activates"},{"source_artifact_id":"wiki-mechanisms-chaperone-mediated-autophagy-neurodegeneration","link_type":"see_also","strength":0.6,"evidence":"KG edge: activates"},{"source_artifact_id":"hypothesis-h-57862f8a","link_type":"mentions","strength":0.5,"evidence":"Entity GPX4 in hypothesis text"},{"source_artifact_id":"hypothesis-h-aa8b4952","link_type":"mentions","strength":0.5,"evidence":"Entity GPX4 in hypothesis text"},{"source_artifact_id":"hypothesis-h-98b431ba","link_type":"mentions","strength":0.5,"evidence":"Entity GPX4 in hypothesis text"},{"source_artifact_id":"hypothesis-h-seaad-v4-26ba859b","link_type":"mentions","strength":0.5,"evidence":"Entity GPX4 in hypothesis text"},{"source_artifact_id":"experiment-exp-wiki-experiments-ferroptosis-parkinsons","link_type":"mentions","strength":0.5,"evidence":"Entity GPX4 in experiment"},{"source_artifact_id":"hypothesis-h-cb833ed8","link_type":"related","strength":0.4,"evidence":"KG bridge: GPX4 ↔ CD38/NAMPT"},{"source_artifact_id":"hypothesis-h-1a34778f","link_type":"related","strength":0.4,"evidence":"KG bridge: GPX4 ↔ CGAS/STING1/DNASE2"},{"source_artifact_id":"hypothesis-h-bb518928","link_type":"related","strength":0.4,"evidence":"KG bridge: GPX4 ↔ PLA2G6/PLA2G4A"},{"source_artifact_id":"notebook-h-seaad-v4-26ba859b","link_type":"see_also","strength":0.7,"evidence":"Notebook entity 'GPX4' matches wiki page"},{"source_artifact_id":"analysis-SDA-2026-04-01-gap-004","link_type":"related","strength":0.5,"evidence":"Reverse link"},{"source_artifact_id":"analysis-SDA-2026-04-01-gap-008","link_type":"related","strength":0.5,"evidence":"Reverse link"},{"source_artifact_id":"analysis-SDA-2026-04-01-gap-012","link_type":"related","strength":0.5,"evidence":"Reverse link"},{"source_artifact_id":"analysis-SDA-2026-04-01-gap-014","link_type":"related","strength":0.5,"evidence":"Reverse link"},{"source_artifact_id":"analysis-SDA-2026-04-01-gap-lipid-rafts-2026-04-01","link_type":"related","strength":0.5,"evidence":"Reverse link"},{"source_artifact_id":"analysis-SDA-2026-04-01-gap-v2-68d9c9c1","link_type":"related","strength":0.5,"evidence":"Reverse link"},{"source_artifact_id":"analysis-SDA-2026-04-01-gap-v2-89432b95","link_type":"related","strength":0.5,"evidence":"Reverse link"},{"source_artifact_id":"analysis-SDA-2026-04-01-gap-v2-bc5f270e","link_type":"related","strength":0.5,"evidence":"Reverse link"},{"source_artifact_id":"analysis-SDA-2026-04-01-gap-v2-ee5a5023","link_type":"related","strength":0.5,"evidence":"Reverse link"},{"source_artifact_id":"analysis-SDA-2026-04-02-26abc5e5f9f2","link_type":"related","strength":0.5,"evidence":"Reverse link"},{"source_artifact_id":"analysis-SDA-2026-04-02-gap-epigenetic-reprog-b685190e","link_type":"related","strength":0.5,"evidence":"Reverse link"},{"source_artifact_id":"analysis-SDA-2026-04-02-gap-seaad-v4-20260402065846","link_type":"related","strength":0.5,"evidence":"Reverse link"},{"source_artifact_id":"hypothesis-h-7957bb2a","link_type":"see_also","strength":0.7,"evidence":"Hypothesis targets gene GPX4 discussed in wiki page"},{"source_artifact_id":"analysis-SDA-2026-04-01-gap-20260401-225149","link_type":"related","strength":0.5,"evidence":"Reverse link"}],"current_artifact_id":"wiki-genes-gpx4","is_canonical":true,"supersede_chain":["wiki-genes-gpx4"]}