{"artifact":{"id":"wiki-genes-lrp8","artifact_type":"wiki_page","entity_ids":"[\"LRP8\"]","title":"LRP8 Gene","quality_score":0.5,"created_by":"crosslink-migration","provenance_chain":"[]","content_hash":"af0052ede82f2ec87c4de2b1e6f7b7c6a016b43495c27f873473a20114d474d2","metadata":{"slug":"genes-lrp8","kg_node_id":"LRP8","entity_type":"gene","origin_type":"v1_polymorphic_backfill","source_table":"wiki_pages","wiki_page_id":"wp-5b0910ecdc6c","__merged_from":{"merged_at":"2026-05-13","unprefixed_id":"genes-lrp8"},"_schema_version":1},"created_at":"2026-04-02T07:19:22-07:00","updated_at":"2026-04-02T13:40:08-07:00","version_number":5,"parent_version_id":null,"version_tag":null,"changelog":null,"is_latest":1,"lifecycle_state":"active","superseded_by":null,"deprecated_at":null,"deprecated_reason":null,"dependencies":null,"market_price":0.5,"origin_type":"internal","origin_url":null,"lifecycle_changed_at":"2026-04-02T13:40:08-07:00","citation_count":0,"embed_count":0,"derivation_count":0,"support_count":0,"contradiction_count":0,"total_usage":0.0,"usage_score":0.5,"usage_computed_at":null,"quality_status":"ok","contributors":[],"answers_question_ids":null,"deprecated_reason_detail":null,"deprecated_reason_code":null,"commit_sha":null,"commit_submodule":null,"last_mutated_at":"2026-05-16T14:51:34.657673-07:00","disputed_at":null,"gap_id":null,"mission_id":null,"intrinsic_priority":null,"effective_priority":null,"artifact_id":"f4d40937-ffd2-4bc4-bc21-c3f69411c80a","artifact_dir":null,"primary_filename":null,"accessory_filenames":null,"folder_layout_version":1,"migrated_to_folder_at":null,"hypothesis_id":null,"authorship":{"kind":"human","contributors":[{"role":"author","actor_ref":"crosslink-migration"}]},"epistemic_tier":"T3_provisional","created_by_agent_id":null},"outgoing_links":[{"target_artifact_id":"hypothesis-h-ac55ff26","link_type":"mentions","strength":0.5,"evidence":"Wiki page title/slug matches hypothesis keyword 'Gene'"},{"target_artifact_id":"hypothesis-h-2600483e","link_type":"mentions","strength":0.5,"evidence":"Wiki page title/slug matches hypothesis keyword 'Gene'"},{"target_artifact_id":"analysis-SDA-2026-04-02-26abc5e5f9f2","link_type":"mentions","strength":0.4,"evidence":"Wiki page matches analysis keyword 'genes'"},{"target_artifact_id":"hypothesis-h-7e0b5ade","link_type":"mentions","strength":0.5,"evidence":"Entity 'LRP8' mentioned in hypothesis description/evidence"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-008","link_type":"mentions","strength":0.35,"evidence":"Via hypothesis description entity 'LRP8'"},{"target_artifact_id":"hypothesis-h-b948c32c","link_type":"mentions","strength":0.5,"evidence":"Entity 'LRP8' mentioned in hypothesis description/evidence"},{"target_artifact_id":"hypothesis-h-73e4340b","link_type":"mentions","strength":0.5,"evidence":"Entity 'LRP8' mentioned in hypothesis description/evidence"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-v2-ee5a5023","link_type":"mentions","strength":0.35,"evidence":"Via hypothesis description entity 'LRP8'"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-lipid-rafts-2026-04-01","link_type":"related","strength":0.5,"evidence":"Auto: transitive via hypothesis"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-v2-ee5a5023","link_type":"related","strength":0.5,"evidence":"Auto: transitive via hypothesis"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-008","link_type":"related","strength":0.5,"evidence":"Auto: transitive via hypothesis"},{"target_artifact_id":"analysis-SDA-2026-04-01-gap-014","link_type":"related","strength":0.5,"evidence":"Auto: transitive via hypothesis"},{"target_artifact_id":"hypothesis-h-4dd0d19b","link_type":"mentions","strength":0.5,"evidence":"KG transitive via LRP1"},{"target_artifact_id":"hypothesis-h-856feb98","link_type":"mentions","strength":0.5,"evidence":"KG transitive via BDNF"},{"target_artifact_id":"wiki-genes-abca2","link_type":"see_also","strength":0.6,"evidence":"KG edge: activates"},{"target_artifact_id":"wiki-genes-apoa1","link_type":"see_also","strength":0.6,"evidence":"KG edge: activates"},{"target_artifact_id":"wiki-genes-apoc1","link_type":"see_also","strength":0.6,"evidence":"KG edge: activates"},{"target_artifact_id":"wiki-genes-apoc2","link_type":"see_also","strength":0.6,"evidence":"KG edge: activates"},{"target_artifact_id":"wiki-genes-abca1","link_type":"see_also","strength":0.6,"evidence":"KG edge: activates"},{"target_artifact_id":"wiki-mechanisms-aging-vs-neurodegeneration-comparison","link_type":"see_also","strength":0.6,"evidence":"KG edge: associated_with"},{"target_artifact_id":"wiki-institutions-alzheimer-indonesia","link_type":"see_also","strength":0.6,"evidence":"KG edge: degrades"},{"target_artifact_id":"wiki-genes-apoc3","link_type":"see_also","strength":0.6,"evidence":"KG edge: activates"},{"target_artifact_id":"wiki-hypotheses-apoe-contributes-alzheimers-disease-regulat","link_type":"see_also","strength":0.6,"evidence":"KG edge: activates"},{"target_artifact_id":"wiki-ideas-payload-app-dosage-reduction-ds-therapy","link_type":"see_also","strength":0.6,"evidence":"KG edge: regulates"},{"target_artifact_id":"wiki-genes-bdnf","link_type":"see_also","strength":0.6,"evidence":"KG edge: activates"},{"target_artifact_id":"wiki-genes-cyp46a1","link_type":"see_also","strength":0.6,"evidence":"KG edge: activates"},{"target_artifact_id":"wiki-experiments-exercise-bdnf-mitophagy-parkinsons","link_type":"see_also","strength":0.6,"evidence":"KG edge: associated_with"},{"target_artifact_id":"analysis-SDA-2026-04-02-gap-tau-prop-20260402003221","link_type":"related","strength":0.5,"evidence":"{\"via\":\"hypothesis_parent\"}"},{"target_artifact_id":"hypothesis-h-d0a564e8","link_type":"mentions","strength":0.5,"evidence":"Wiki content mentions gene APOE"},{"target_artifact_id":"hypothesis-h-44195347","link_type":"mentions","strength":0.5,"evidence":"Wiki content mentions gene APOE"},{"target_artifact_id":"hypothesis-h-11795af0","link_type":"mentions","strength":0.5,"evidence":"Wiki content mentions gene APOE"},{"target_artifact_id":"hypothesis-h-99b4e2d2","link_type":"mentions","strength":0.5,"evidence":"Wiki content mentions gene APOE"},{"target_artifact_id":"hypothesis-h-a20e0cbb","link_type":"mentions","strength":0.5,"evidence":"Wiki content mentions gene APOE"},{"target_artifact_id":"hypothesis-h-seaad-fa5ea82d","link_type":"mentions","strength":0.5,"evidence":"Wiki content mentions gene APOE"},{"target_artifact_id":"hypothesis-h-c9c79e3e","link_type":"mentions","strength":0.5,"evidence":"Wiki content mentions gene APOE"},{"target_artifact_id":"hypothesis-h-15336069","link_type":"mentions","strength":0.5,"evidence":"Wiki content mentions gene APOE"},{"target_artifact_id":"hypothesis-h-d2df6eaf","link_type":"related","strength":0.5,"evidence":"Wiki relates to pathway: Reelin signaling"},{"target_artifact_id":"hypothesis-h-84808267","link_type":"mentions","strength":0.7,"evidence":"Wiki content mentions gene LRP1"}],"incoming_links":[{"source_artifact_id":"hypothesis-h-84808267","link_type":"related","strength":0.63,"evidence":"Reverse: Wiki content mentions gene LRP1"},{"source_artifact_id":"hypothesis-h-ac55ff26","link_type":"related","strength":0.4,"evidence":"Auto: reverse of wiki→hypothesis"},{"source_artifact_id":"hypothesis-h-2600483e","link_type":"related","strength":0.4,"evidence":"Auto: reverse of wiki→hypothesis"},{"source_artifact_id":"hypothesis-h-7e0b5ade","link_type":"related","strength":0.4,"evidence":"Auto: reverse of wiki→hypothesis"},{"source_artifact_id":"hypothesis-h-b948c32c","link_type":"related","strength":0.4,"evidence":"Auto: reverse of wiki→hypothesis"},{"source_artifact_id":"hypothesis-h-73e4340b","link_type":"related","strength":0.4,"evidence":"Auto: reverse of wiki→hypothesis"},{"source_artifact_id":"analysis-SDA-2026-04-01-gap-008","link_type":"related","strength":0.5,"evidence":"Reverse link"},{"source_artifact_id":"analysis-SDA-2026-04-01-gap-014","link_type":"related","strength":0.5,"evidence":"Reverse link"},{"source_artifact_id":"analysis-SDA-2026-04-01-gap-lipid-rafts-2026-04-01","link_type":"related","strength":0.5,"evidence":"Reverse link"},{"source_artifact_id":"analysis-SDA-2026-04-01-gap-v2-ee5a5023","link_type":"related","strength":0.5,"evidence":"Reverse link"},{"source_artifact_id":"analysis-SDA-2026-04-02-26abc5e5f9f2","link_type":"related","strength":0.5,"evidence":"Reverse link"}],"current_artifact_id":"wiki-genes-lrp8","is_canonical":true,"supersede_chain":["wiki-genes-lrp8"]}