% Bibliography for hypothesis h-0e0cc0c1
% Title: Circadian-Synchronized Proteostasis Enhancement
% Generated: 2026-06-07T21:28:05Z

@article{pmid41521387,
  title = {Fasting as Medicine: Mitochondrial and Endothelial Rejuvenation in Vascular Aging.},
  author = {["Milan M", "Troyano-Rodriguez E", "Ihuoma J", "Negri S", "Rudraboina R", "Kosmider A", "Awasthi S", "Balasubramanian P", "Conley S", "Yabluchanskiy A"]},
  journal = {Aging cell},
  year = {2026},
  pmid = {41521387},
  doi = {10.1111/acel.70372},
}

@article{pmid39995020,
  title = {Circadian clock genes and cell survival in bipolar disorder: Insights into lithium responsiveness and molecular mechanisms in patient-derived neural progenitor cells and mouse neurons.},
  author = {["Mishra H", "Wei H", "LeRoux M", "Ko D", "Rohr K", "Nievergelt C", "Maihofer A", "Shilling P", "Alda M", "Berrettini W"]},
  journal = {The FEBS journal},
  year = {2025},
  pmid = {39995020},
  doi = {10.1111/febs.70034},
}

@article{pmid40119168,
  title = {Rapamycin mitigates neurotoxicity of fluoride and aluminum by activating autophagy through the AMPK/mTOR/ULK1 pathway in hippocampal neurons and NG108-15 cells.},
  author = {["Tao D", "Xia Y", "Liao Q", "Yang X", "Zhang L", "Xie C"]},
  journal = {Scientific reports},
  year = {2025},
  pmid = {40119168},
  doi = {10.1038/s41598-025-94648-0},
}

@article{pmid40202498,
  title = {Rhythmic TDP-43 affects RNA splicing of USP13, resulting in alteration of BMAL1 ubiquitination.},
  author = {["Gu J", "Yang M", "Zhang L", "Liu Y", "Yan R", "Pan D", "Qian X", "Hu H", "Chu D", "Hu C"]},
  journal = {The Journal of cell biology},
  year = {2025},
  pmid = {40202498},
  doi = {10.1083/jcb.202405142},
}

@article{pmid40250404,
  title = {From geroscience to precision geromedicine: Understanding and managing aging.},
  author = {Kroemer G, Maier AB, Cuervo AM, Gladyshev VN, Ferrucci L, Gorbunova V, Kennedy BK, Rando TA, Seluanov A, Sierra F},
  journal = {Cell},
  year = {2025},
  pmid = {40250404},
  doi = {10.1016/j.cell.2025.03.011},
  url = {https://pubmed.ncbi.nlm.nih.gov/40250404},
}

@article{pmid40506775,
  title = {Exercise orchestrates systemic metabolic and neuroimmune homeostasis via the brain-muscle-liver axis to slow down aging and neurodegeneration: a narrative review.},
  author = {["Kong J", "Xie Y", "Fan R", "Wang Q", "Luo Y", "Dong P"]},
  journal = {European journal of medical research},
  year = {2025},
  pmid = {40506775},
  doi = {10.1186/s40001-025-02751-9},
}

@article{pmid40862757,
  title = {Cellular Models of Aging and Senescence.},
  author = {Kim B, Lee DI, Basisty N, Dai DF},
  journal = {Cells},
  year = {2025},
  pmid = {40862757},
  doi = {10.3390/cells14161278},
  url = {https://pubmed.ncbi.nlm.nih.gov/40862757/},
}

@article{pmid41123484,
  title = {Circadian clock genes and insomnia: molecular mechanisms and therapeutic implications.},
  author = {Ren Q, Gu M, Fan X},
  journal = {Ann Med},
  year = {2025},
  pmid = {41123484},
  doi = {10.1080/07853890.2025.2576643},
  url = {https://pubmed.ncbi.nlm.nih.gov/41123484/},
}

@article{pmid41287625,
  title = {Circadian Rhythm Dysfunction in Neurodegenerative Diseases: A Bidirectional Perspective and Therapeutic Potential.},
  author = {Namgyal D, Lim CS},
  journal = {Nature and science of sleep},
  year = {2025},
  pmid = {41287625},
  doi = {10.2147/NSS.S561326},
  url = {https://pubmed.ncbi.nlm.nih.gov/41287625/},
}

@article{pmid41335394,
  title = {Orexin-A and Circadian Disruption in Alzheimer's Disease: Implications for Amyloid-Beta Pathology.},
  author = {["Singh R", "Kaur V", "Ash A", "Singh M", "Tiwari A", "Jain A", "Sunkaria A"]},
  journal = {Molecular neurobiology},
  year = {2025},
  pmid = {41335394},
  doi = {10.1007/s12035-025-05456-6},
}

@article{pmid38746315,
  title = {Differential contributions of circadian clock genes to cell survival in bipolar disorder patient derived neuronal progenitor cells distinguishes lithium responders and non-responders.},
  author = {["Mishra H", "Wei H", "LeRoux M", "Ko I", "Rohr K", "Nievergelt C", "Maihofer A", "Shilling P", "Alda M", "Berrettini W"]},
  journal = {Research square},
  year = {2024},
  pmid = {38746315},
  doi = {10.21203/rs.3.rs-4331810/v1},
}

@article{pmid39596274,
  title = {Manganese Exposure Enhances the Release of Misfolded α-Synuclein via Exosomes by Impairing Endosomal Trafficking and Protein Degradation Mechanisms.},
  author = {["Rokad D", "Harischandra D", "Samidurai M", "Chang Y", "Luo J", "Lawana V", "Sarkar S", "Palanisamy B", "Manne S", "Kim D"]},
  journal = {International journal of molecular sciences},
  year = {2024},
  pmid = {39596274},
  doi = {10.3390/ijms252212207},
}

@article{pmid37086572,
  title = {BMAL1 involved in autophagy and injury of thoracic aortic endothelial cells of rats induced by intermittent heat stress through the AMPK/mTOR/ULK1 pathway.},
  author = {Chunli Yang, Ziwei Deng, Qihang Zeng, Xiaoyu Chang, Xiaomin Wu et al.},
  journal = {Biochemical and biophysical research communications},
  year = {2023},
  pmid = {37086572},
  doi = {10.1016/j.bbrc.2023.04.035},
  url = {https://pubmed.ncbi.nlm.nih.gov/37086572},
}

@article{pmid37126998,
  title = {Contributions of circadian clock genes to cell survival in fibroblast models of lithium-responsive bipolar disorder.},
  author = {["Mishra H", "Wei H", "Rohr K", "Ko I", "Nievergelt C", "Maihofer A", "Shilling P", "Alda M", "Berrettini W", "Brennand K"]},
  journal = {European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology},
  year = {2023},
  pmid = {37126998},
  doi = {10.1016/j.euroneuro.2023.04.009},
}

@article{pmid37887295,
  title = {Reappraisal of the Concept of Accelerated Aging in Neurodegeneration and Beyond.},
  author = {["Statsenko Y", "Kuznetsov N", "Morozova D", "Liaonchyk K", "Simiyu G", "Smetanina D", "Kashapov A", "Meribout S", "Gorkom K", "Hamoudi R"]},
  journal = {Cells},
  year = {2023},
  pmid = {37887295},
  doi = {10.3390/cells12202451},
}

@article{pmid33634751,
  title = {Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)},
  author = {["Klionsky D", "Abdel-Aziz A", "Abdelfatah S", "Abdellatif M", "Abdoli A", "Abel S", "Abeliovich H", "Abildgaard M", "Abudu Y", "Acevedo-Arozena A"]},
  journal = {Autophagy},
  year = {2021},
  pmid = {33634751},
  doi = {10.1080/15548627.2020.1797280},
}

@article{pmid34596047,
  title = {Defining circadian disruption in neurodegenerative disorders.},
  author = {["Colwell C"]},
  journal = {The Journal of clinical investigation},
  year = {2021},
  pmid = {34596047},
  doi = {10.1172/JCI148288},
}

@article{pmid31726888,
  title = {Obestatin attenuated methamphetamine-induced PC12 cells neurotoxicity via inhibiting autophagy and apoptosis.},
  author = {["Foroughi K", "Jahanbani S", "Khaksari M", "Shayannia A"]},
  journal = {Human & experimental toxicology},
  year = {2020},
  pmid = {31726888},
  doi = {10.1177/0960327119886036},
}

@article{pmid30943415,
  title = {Circadian Clocks Function in Concert with Heat Shock Organizing Protein to Modulate Mutant Huntingtin Aggregation and Toxicity.},
  author = {["Xu F", "Kula-Eversole E", "Iwanaszko M", "Hutchison A", "Dinner A", "Allada R"]},
  journal = {Cell reports},
  year = {2019},
  pmid = {30943415},
  doi = {10.1016/j.celrep.2019.03.015},
}