% Bibliography for hypothesis h-0e675a41
% Title: Selective HDAC3 Inhibition with Cognitive Enhancement
% Generated: 2026-04-28T18:42:39Z

@article{pmid41023273,
  title = {HDAC3 mediates retinal endothelial cell metabolic reprogramming and angiogenesis.},
  author = {Mitchell CD, Morris CA, Wild M, Cunningham A, Chuesiang P et al.},
  journal = {Acta Pharmacol Sin},
  year = {2026},
  pmid = {41023273},
  doi = {doi: 10.1038/s41401-025-01642-3},
  url = {https://pubmed.ncbi.nlm.nih.gov/41023273/},
}

@article{pmid41352543,
  title = {Metabolomics identifies riboflavin as a therapeutic agent for acute pancreatitis.},
  author = {Shi Y, Peng J},
  journal = {J Nutr Biochem},
  year = {2026},
  pmid = {41352543},
  doi = {doi: 10.1016/j.jnutbio.2025.110225},
  url = {https://pubmed.ncbi.nlm.nih.gov/41352543/},
}

@article{pmid41535708,
  title = {β-Hydroxybutyrate improves glymphatic system function and alleviates cerebral edema in mice after ischemic stroke.},
  author = {Yu MJ, Xiong RQ, Wu JW, Li YC, Xie JX et al.},
  journal = {Acta Pharmacol Sin},
  year = {2026},
  pmid = {41535708},
  doi = {doi: 10.1038/s41401-025-01706-4},
  url = {https://pubmed.ncbi.nlm.nih.gov/41535708/},
}

@article{pmid41736683,
  title = {SATB2 Mediates H3K9 Delactylation by Recruiting HDAC3 to Repress LCN2 and Inhibit Lung Tumor Growth and Metastasis.},
  author = {Wen T, Yang L, Cai S, Liu Y, Fan J et al.},
  journal = {Adv Sci (Weinh)},
  year = {2026},
  pmid = {41736683},
  doi = {doi: 10.1002/advs.202522996},
  url = {https://pubmed.ncbi.nlm.nih.gov/41736683/},
}

@article{pmid41783166,
  title = {Histone deacetylases: Function in tumor development and therapeutic prospects (Review).},
  author = {Lin R, Zhang Y, Li H, Liang F},
  journal = {Oncol Lett},
  year = {2026},
  pmid = {41783166},
  doi = {doi: 10.3892/ol.2026.15497},
  url = {https://pubmed.ncbi.nlm.nih.gov/41783166/},
}

@article{pmid41812251,
  title = {Discovery of a Covalent HDAC3 Degrader with Excellent Anti-Inflammatory Activity and NLRP3 Inflammasome Suppression.},
  author = {["Qin H", "Shi Y", "Liu R", "Wang B", "Guo L", "Hao G", "Zhang G", "Liu D", "Zhao L", "Huang M"]},
  journal = {Journal of medicinal chemistry},
  year = {2026},
  pmid = {41812251},
  doi = {10.1021/acs.jmedchem.5c02513},
}

@article{pmid41829110,
  title = {The Mechanism of GABA in Attenuating Neuroinflammation in Alzheimer's Disease: CP/CEBPα/miR-34a-Mediated Suppression of HDAC2/3 in Astrocytes.},
  author = {["Zhang J", "Wu S", "Meng N", "Li C", "Zhao Y", "An L"]},
  journal = {Foods (Basel, Switzerland)},
  year = {2026},
  pmid = {41829110},
  doi = {10.3390/foods15050837},
}

@article{pmid41837847,
  title = {GR/HDAC3 Regulates Npas4 Signaling Pathway and Mediates Cognitive Impairment in Prenatal Hypoxia Male Offspring.},
  author = {Zhao Z, Song Y, Yu X, Gao Q, Wang B, Sun M},
  journal = {FASEB journal : official publication of the Federation of American Societies for Experimental Biology},
  year = {2026},
  pmid = {41837847},
  doi = {10.1096/fj.202502736R},
  url = {https://pubmed.ncbi.nlm.nih.gov/41837847/},
}

@article{pmid41844502,
  title = {LncRNA SNHG5 promotes macrophage lipid accumulation and aggravates atherosclerosis by targeting the miR-216a-5p/HDAC3/ABCA1 axis.},
  author = {Liu X, Wang HH, Lan XY, Sun SY, Xu XD, Hui L, Xu GH, Zhu L, Ren K},
  journal = {Biochimica et biophysica acta. Molecular and cell biology of lipids},
  year = {2026},
  pmid = {41844502},
  doi = {10.1016/j.bbalip.2026.159738},
  url = {https://pubmed.ncbi.nlm.nih.gov/41844502/},
}

@article{pmid41851071,
  title = {Myeloid HDAC3 deletion protects against traumatic optic injury.},
  author = {Shahror RA, Morris CA, Cunningham A, Chuesiang P, Fouda AY},
  journal = {Cell death discovery},
  year = {2026},
  pmid = {41851071},
  doi = {10.1038/s41420-026-03030-0},
  url = {https://pubmed.ncbi.nlm.nih.gov/41851071/},
}

@article{pmid41876476,
  title = {EXPRESS: Identification of Acetylation-Related Molecular Signatures in Knee Osteoarthritis Patients with Significant Response to Warm-Needle Acupuncture Using Machine-Learning Approaches.},
  author = {Wang J, Xu B, Yoon DE, Xu S, Xia S, Xu J, Fang X, Wu H, Chae Y, Mi Y},
  journal = {Molecular pain},
  year = {2026},
  pmid = {41876476},
  doi = {10.1177/17448069261439615},
  url = {https://pubmed.ncbi.nlm.nih.gov/41876476/},
}

@article{pmid41888851,
  title = {Microglial HDAC3 inhibits the migration of CD8-positive T cell in the development of EAE by restraining the expression of CCL5.},
  author = {Na Che; Yang Zhang; Bo Wang; Hongxing Wu; Zhiqiong Mao; Zengqiang Yuan; Xiangxi Kong; Yajin Liao},
  journal = {Cell & bioscience},
  year = {2026},
  pmid = {41888851},
  doi = {10.1186/s13578-026-01564-5},
  url = {https://pubmed.ncbi.nlm.nih.gov/41888851/},
}

@article{pmid41912135,
  title = {HOX code-based stratification reveals RUNX1T1-HDAC reprogramming as a targetable driver of lineage plasticity across cancers.},
  author = {Jiang Y, Cheng S, Zhang CY, Jin X, Li L, Shin HE, Alrefai A, Luo A, Xu Y, Kim IY, Mu P},
  journal = {Cancer letters},
  year = {2026},
  pmid = {41912135},
  doi = {10.1016/j.canlet.2026.218465},
  url = {https://pubmed.ncbi.nlm.nih.gov/41912135/},
}

@article{pmid39824811,
  title = {NKAPL facilitates transcription pause-release and bridges elongation to initiation during meiosis exit.},
  author = {["Kang Z", "Xu C", "Lu S", "Gong J", "Yan R", "Luo G", "Wang Y", "He Q", "Wu Y", "Yan Y"]},
  journal = {Nature communications},
  year = {2025},
  pmid = {39824811},
  doi = {10.1038/s41467-024-55579-y},
}

@article{pmid40485011,
  title = {Targeting HDAC3 Suppresses Ferroptosis and Demyelination in White Matter Injury by Restoring PDK4-Mediated Iron Homeostasis.},
  author = {["Xu T", "Ye L", "Li W", "Liu F", "Wei T", "Gu W", "Xu L", "Fang M", "Luo Q", "Wu C"]},
  journal = {CNS neuroscience & therapeutics},
  year = {2025},
  pmid = {40485011},
  doi = {10.1111/cns.70471},
}

@article{pmid40667573,
  title = {Epigenetic therapy meets targeted protein degradation: HDAC-PROTACs in cancer treatment.},
  author = {["Hussain M", "Zhang L", "Rana A", "Maqbool M", "Ashique S", "Khan Y", "Jakhmola V", "Hanbashi A", "Mawkili W", "Khan G"]},
  journal = {Future medicinal chemistry},
  year = {2025},
  pmid = {40667573},
  doi = {10.1080/17568919.2025.2533113},
}

@article{pmid41153431,
  title = {Epigenetic Modulation and Neuroprotective Effects of Neurofabine-C in a Transgenic Model of Alzheimer's Disease.},
  author = {["Carrera I", "Naidoo V", "Corzo L", "Mart\u00ednez-Iglesias O", "Cacabelos R"]},
  journal = {Genes},
  year = {2025},
  pmid = {41153431},
  doi = {10.3390/genes16101214},
}

@article{pmid41160773,
  title = {PROTAC-Based HDAC Degradation: A Paradigm Shift in Targeted Epigenetic Therapies.},
  author = {Himaja A, Halder D, Banerjee S, Biswas S, Adhikari N, Ghosh B},
  journal = {ChemMedChem},
  year = {2025},
  pmid = {41160773},
  doi = {10.1002/cmdc.202500203},
  url = {https://pubmed.ncbi.nlm.nih.gov/41160773/},
}

@article{pmid37721401,
  title = {Melatonin attenuates chronic sleep deprivation-induced cognitive deficits and HDAC3-Bmal1/clock interruption.},
  author = {Hu Y, Lv Y, Long X, Yang G, Zhou J},
  journal = {CNS neuroscience & therapeutics},
  year = {2024},
  pmid = {37721401},
  doi = {10.1111/cns.14474},
  url = {https://pubmed.ncbi.nlm.nih.gov/37721401/},
}

@article{pmid38295798,
  title = {Microbiota-derived butyrate restricts tuft cell differentiation via histone deacetylase 3 to modulate intestinal type 2 immunity.},
  author = {Eshleman EM, Rice T, Potter C, Waddell A, Hashimoto-Hill S, Woo V, Field S, Engleman L, Lim HW, Schumacher MA, Frey MR, Denson LA, Finkelman FD, Alenghat T},
  journal = {Immunity},
  year = {2024},
  pmid = {38295798},
  doi = {10.1016/j.immuni.2024.01.002},
  url = {https://pubmed.ncbi.nlm.nih.gov/38295798/},
}

@article{pmid38321930,
  title = {Unlocking the epigenetic symphony: histone acetylation's impact on neurobehavioral change in neurodegenerative disorders.},
  author = {["Basavarajappa B", "Subbanna S"]},
  journal = {Epigenomics},
  year = {2024},
  pmid = {38321930},
  doi = {10.2217/epi-2023-0428},
}

@article{pmid38378993,
  title = {A phenotypic screening platform for identifying chemical modulators of astrocyte reactivity.},
  author = {Clayton BLL, Kristell JD, Allan KC, Cohn EF, Karl M, Jerome AD, Garrison E, Maeno-Hikichi Y, Sturno AM, Kerr A, Shick HE, Sepeda JA, Freundt EC, Sas AR, Segal BM, Miller RH, Tesar PJ},
  journal = {Nature neuroscience},
  year = {2024},
  pmid = {38378993},
  doi = {10.1038/s41593-024-01580-z},
  url = {https://pubmed.ncbi.nlm.nih.gov/38378993/},
}

@article{pmid38711064,
  title = {Deficiency of histone deacetylases 3 in macrophage alleviates monosodium urate crystals-induced gouty inflammation in mice.},
  author = {["Yang Q", "Zhang M", "Yang L", "Wang J", "Mi Q", "Zhou J"]},
  journal = {Arthritis research & therapy},
  year = {2024},
  pmid = {38711064},
  doi = {10.1186/s13075-024-03335-4},
}

@article{pmid38997746,
  title = {Deletion of myeloid HDAC3 promotes efferocytosis to ameliorate retinal ischemic injury.},
  author = {["Shahror R", "Shosha E", "Morris C", "Wild M", "Mu S", "Csanyi G", "Boerma M", "Rusch N", "Fouda A"]},
  journal = {Journal of neuroinflammation},
  year = {2024},
  pmid = {38997746},
  doi = {10.1186/s12974-024-03159-8},
}

@article{pmid39513228,
  title = {The Two Faces of HDAC3: Neuroinflammation in Disease and Neuroprotection in Recovery.},
  author = {Rosete C, Ciernia AV},
  journal = {Epigenomics},
  year = {2024},
  pmid = {39513228},
  doi = {10.1080/17501911.2024.2419357},
  url = {https://pubmed.ncbi.nlm.nih.gov/39513228/},
}

@article{pmid37244125,
  title = {HDAC3 deficiency protects against acute lung injury by maintaining epithelial barrier integrity through preserving mitochondrial quality control.},
  author = {["Li N", "Liu B", "Xiong R", "Li G", "Wang B", "Geng Q"]},
  journal = {Redox biology},
  year = {2023},
  pmid = {37244125},
  doi = {10.1016/j.redox.2023.102746},
}

@article{pmid37466915,
  title = {Ketogenic diet attenuates neuroinflammation and induces conversion of M1 microglia to M2 in an EAE model of multiple sclerosis by regulating the NF-κB/NLRP3 pathway and inhibiting HDAC3 and P2X7R activation.},
  author = {Sun W, Wang Q, Zhang R, Zhang N},
  journal = {Food & function},
  year = {2023},
  pmid = {37466915},
  doi = {10.1039/d3fo00122a},
  url = {https://pubmed.ncbi.nlm.nih.gov/37466915/},
}

@article{pmid37890360,
  title = {HDAC3 aberration-incurred GPX4 suppression drives renal ferroptosis and AKI-CKD progression.},
  author = {Zhang L, Chen F, Dong J, Wang R, Bi G, Xu D, Zhang Y, Deng Y, Lin W, Yang Z, Cao W},
  journal = {Redox biology},
  year = {2023},
  pmid = {37890360},
  doi = {10.1016/j.redox.2023.102939},
  url = {https://pubmed.ncbi.nlm.nih.gov/37890360/},
}

@article{pmid34151764,
  title = {Understanding the Role of Histone Deacetylase and their Inhibitors in Neurodegenerative Disorders: Current Targets and Future Perspective.},
  author = {Kumar V, Kundu S, Singh A, Singh S},
  journal = {Current neuropharmacology},
  year = {2022},
  pmid = {34151764},
  doi = {10.2174/1570159X19666210609160017},
  url = {https://pubmed.ncbi.nlm.nih.gov/34151764/},
}

@article{pmid34151764,
  title = {Understanding the Role of Histone Deacetylase and their Inhibitors in Neurodegenerative Disorders: Current Targets and Future Perspective.},
  author = {Kumar V, Kundu S, Singh A, Singh S},
  journal = {Curr Neuropharmacol},
  year = {2022},
  pmid = {34151764},
  doi = {doi: 10.2174/1570159X19666210609160017},
  url = {https://pubmed.ncbi.nlm.nih.gov/34151764/},
}

@article{pmid35586419,
  title = {Determination of Slow-Binding HDAC Inhibitor Potency and Subclass Selectivity.},
  author = {Moreno-Yruela C, Olsen CA},
  journal = {ACS medicinal chemistry letters},
  year = {2022},
  pmid = {35586419},
  doi = {10.1021/acsmedchemlett.1c00702},
  url = {https://pubmed.ncbi.nlm.nih.gov/35586419/},
}

@article{pmid36046456,
  title = {HDAC3 Inhibition Alleviates High-Glucose-Induced Retinal Ganglion Cell Death through Inhibiting Inflammasome Activation.},
  author = {["Yu D", "Tang Q", "Liu L", "He D", "Wang L", "Zhou X"]},
  journal = {BioMed research international},
  year = {2022},
  pmid = {36046456},
  doi = {10.1155/2022/4164824},
}

@article{pmid32486848,
  title = {Histone deacetylase-3: Friend and foe of the brain.},
  author = {D'Mello SR},
  journal = {Experimental biology and medicine (Maywood, N.J.)},
  year = {2020},
  pmid = {32486848},
  doi = {10.1177/1535370220928278},
  url = {https://pubmed.ncbi.nlm.nih.gov/32486848/},
}

@article{pmid32863951,
  title = {HDAC3 inhibition ameliorates ischemia/reperfusion-induced brain injury by regulating the microglial cGAS-STING pathway.},
  author = {Liao Y, Cheng J, Kong X, Li S, Li X, Zhang M, Zhang H, Yang T, Dong Y, Li J, Xu Y, Yuan Z},
  journal = {Theranostics},
  year = {2020},
  pmid = {32863951},
  doi = {10.7150/thno.47651},
  url = {https://pubmed.ncbi.nlm.nih.gov/32863951/},
}

@article{pmid29211617,
  title = {Targeting HDAC3 Activity with RGFP966 Protects Against Retinal Ganglion Cell Nuclear Atrophy and Apoptosis After Optic Nerve Injury.},
  author = {["Schmitt H", "Schlamp C", "Nickells R"]},
  journal = {Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics},
  year = {2018},
  pmid = {29211617},
  doi = {10.1089/jop.2017.0059},
}

@article{pmid28086213,
  title = {Epigenetic regulation of general anesthesia-induced neonatal neurodegeneration},
  author = {Jia Min; Ji Mu-Huo; Yang Jian-Jun},
  journal = {Oncotarget},
  year = {2017},
  pmid = {28086213},
  doi = {10.18632/oncotarget.14568},
  url = {https://pubmed.ncbi.nlm.nih.gov/28086213/},
}

@article{pmid23913134,
  title = {Histone deacetylase 3 as a novel therapeutic target in multiple myeloma.},
  author = {["Minami J", "Suzuki R", "Mazitschek R", "Gorgun G", "Ghosh B", "Cirstea D", "Hu Y", "Mimura N", "Ohguchi H", "Cottini F"]},
  journal = {Leukemia},
  year = {2014},
  pmid = {23913134},
  doi = {10.1038/leu.2013.231},
}

@article{pmid24954007,
  title = {Selective chemical modulation of gene transcription favors oligodendrocyte lineage progression.},
  author = {["Gacias M", "Gerona-Navarro G", "Plotnikov A", "Zhang G", "Zeng L", "Kaur J", "Moy G", "Rusinova E", "Rodriguez Y", "Matikainen B"]},
  journal = {Chemistry & biology},
  year = {2014},
  pmid = {24954007},
  doi = {10.1016/j.chembiol.2014.05.009},
}

@article{pmid22918830,
  title = {Histone deacetylase-1 (HDAC1) is a molecular switch between neuronal survival and death.},
  author = {["Bardai F", "Price V", "Zaayman M", "Wang L", "D'Mello S"]},
  journal = {The Journal of biological chemistry},
  year = {2012},
  pmid = {22918830},
  doi = {10.1074/jbc.M112.394544},
}

@article{pmid21289184,
  title = {Selective toxicity by HDAC3 in neurons: regulation by Akt and GSK3beta.},
  author = {["Bardai F", "D'Mello S"]},
  journal = {The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year = {2011},
  pmid = {21289184},
  doi = {10.1523/JNEUROSCI.5704-10.2011},
}

@article{pmid18638560,
  title = {Histone deacetylase inhibitors improve learning consolidation in young and in KA-induced-neurodegeneration and SAMP-8-mutant mice.},
  author = {["Font\u00e1n-Lozano A", "Romero-Granados R", "Troncoso J", "M\u00fanera A", "Delgado-Garc\u00eda J", "Carri\u00f3n A"]},
  journal = {Molecular and cellular neurosciences},
  year = {2008},
  pmid = {18638560},
  doi = {10.1016/j.mcn.2008.06.009},
}