% Bibliography for hypothesis h-434c5d45f5
% Title: Dual-Mechanism Model: G2019S Increases Both Baseline AND Signal-Dependent Phosphorylation (H2)
% Generated: 2026-04-28T19:31:01Z

@article{pmid41344986,
  title = {Protective or Pathogenic? Kinase activity and the neurodevelopmental origins of G2019S LRRK2-Associated Parkinson's disease.},
  author = {Gatto EM, Espay AJ, Espindola M, Da Prat G, Kauffman MA},
  journal = {Parkinsonism & related disorders},
  year = {2026},
  pmid = {41344986},
  doi = {10.1016/j.parkreldis.2025.108133},
  url = {https://pubmed.ncbi.nlm.nih.gov/41344986/},
}

@article{pmid34125248,
  title = {R1441G but not G2019S mutation enhances LRRK2 mediated Rab10 phosphorylation in human peripheral blood neutrophils.},
  author = {Fan, Nirujogi, Garrido, Ruiz-Martínez, Bergareche-Yarza et al.},
  journal = {Acta neuropathologica},
  year = {2022},
  pmid = {34125248},
  doi = {10.1007/s00401-021-02325-z},
}

@article{pmid35012605,
  title = {Pathological α-synuclein recruits LRRK2 expressing pro-inflammatory monocytes to the brain.},
  author = {Xu E, Boddu R, Abdelmotilib HA, Sokratian A, Kelly K, Liu Z, Bryant N, Chandra S, Carlisle SM, Lefkowitz EJ, Harms AS, Benveniste EN, Yacoubian TA, Volpicelli-Daley LA, Standaert DG, West AB},
  journal = {Molecular neurodegeneration},
  year = {2022},
  pmid = {35012605},
  doi = {10.1186/s13024-021-00509-5},
  url = {https://pubmed.ncbi.nlm.nih.gov/35012605/},
}

@article{pmid29127255,
  title = {Interrogating Parkinson's disease LRRK2 kinase pathway activity by assessing Rab10 phosphorylation in human neutrophils.},
  author = {["Fan Ying", "Howden Andrew J M", "Sarhan Adil R", "Lis Pawel", "Ito Genta"]},
  journal = {The Biochemical journal},
  year = {2018},
  pmid = {29127255},
  doi = {10.1042/BCJ20170803},
}