% Bibliography for hypothesis h-4dd0d19b
% Title: LRP1-Dependent Tau Uptake Disruption
% Generated: 2026-06-09T04:57:56Z

@article{pmid40609733,
  title = {Osteoclast-secreted galectin-3 promotes articular cartilage degeneration in OVX rats via LRP1/beta-catenin axis.},
  author = {Chen L, Hong H, Yang Z, Zhong Y, Sun S et al.},
  journal = {Osteoarthritis Cartilage},
  year = {2026},
  pmid = {40609733},
  doi = {doi: 10.1016/j.joca.2025.06.013},
  url = {https://pubmed.ncbi.nlm.nih.gov/40609733/},
}

@article{pmid41579784,
  title = {Lysosomal trafficking markers covering PSAP, PGRN, SORT1 and LRP1 in body liquids and cerebral tissue as auxiliary indicative tool of traumatic brain injury.},
  author = {Poniatowski ŁA, Siwińska A, Acewicz A, Kwiatkowska M, Olczak M},
  journal = {Forensic science international},
  year = {2026},
  pmid = {41579784},
  doi = {10.1016/j.forsciint.2026.112829},
  url = {https://pubmed.ncbi.nlm.nih.gov/41579784/},
}

@article{pmid41621577,
  title = {Insulin-like growth factor-1 enhances β-amyloid protein clearance in HMC3 microglia via low-density lipoprotein receptor-related protein 1-mediated pathway.},
  author = {Guo H, Peng X, Zhang X, Ruganzu JB, Wu X, Zhao M, Yang P, Ji S, Yang W},
  journal = {Experimental cell research},
  year = {2026},
  pmid = {41621577},
  doi = {10.1016/j.yexcr.2026.114920},
  url = {https://pubmed.ncbi.nlm.nih.gov/41621577/},
}

@article{pmid41687804,
  title = {Mitochondrial calcium uniporter knockdown in hippocampal neurons effectively attenuates synaptic plasticity impairment and pathology in APP/PS1/tau model of Alzheimer's disease.},
  author = {Wu L, Hou F, Wang Z, Wu M, Wang X, Cao J, Wang Y, Cai H},
  journal = {Experimental neurology},
  year = {2026},
  pmid = {41687804},
  doi = {10.1016/j.expneurol.2026.115686},
  url = {https://pubmed.ncbi.nlm.nih.gov/41687804/},
}

@article{pmid41772271,
  title = {Modulating LRP1 Pathways in Alzheimer's Disease: Mechanistic Insights and Emerging Therapies.},
  author = {Mushtaq T, Hameed H, Khan MA, Tariq U, Hameed A, Zaman M},
  journal = {Molecular neurobiology},
  year = {2026},
  pmid = {41772271},
  doi = {10.1007/s12035-026-05775-2},
  url = {https://pubmed.ncbi.nlm.nih.gov/41772271/},
}

@article{pmid41927877,
  title = {Small-molecule PCSK9 inhibition enhances BBB amyloid-β clearance and suppresses microglial inflammation in Alzheimer's disease models.},
  author = {Miao J, Wang J, Zhou W, Guo J},
  journal = {Sci Rep},
  year = {2026},
  pmid = {41927877},
  doi = {doi: 10.1038/s41598-026-46671-y},
  url = {https://pubmed.ncbi.nlm.nih.gov/41927877/},
}

@article{pmid39713861,
  title = {Microglia internalize tau monomers and fibrils using distinct receptors but similar mechanisms.},
  author = {Falkon KF, Danford L, Gutierrez Kuri E, Esquinca-Moreno P, Peña Señeriz YL, Smith S, Wickline JL, Louwrier A, McPhail JA, Sayre NL, Hopp SC},
  journal = {Alzheimer's & dementia : the journal of the Alzheimer's Association},
  year = {2025},
  pmid = {39713861},
  doi = {10.1002/alz.14418},
  url = {https://pubmed.ncbi.nlm.nih.gov/39713861/},
}

@article{pmid40175345,
  title = {Inhibition of tau neuronal internalization using anti-tau single domain antibodies.},
  author = {["Danis C", "Dupr\u00e9 E", "Bouillet T", "Den\u00e9chaud M", "Lefebvre C", "Nguyen M", "Mortelecque J", "Cantrelle F", "Rain J", "Hanoulle X"]},
  journal = {Nature communications},
  year = {2025},
  pmid = {40175345},
  doi = {10.1038/s41467-025-58383-4},
}

@article{pmid40595262,
  title = {Integrative bioinformatics frameworks for abdominal aortic aneurysm using GWAS meta-analysis, biological network construction, and structural modeling.},
  author = {Sagulkoo P, Chuntakaruk H, Suratanee A, Plaimas K, Teerakulkittipong N},
  journal = {Scientific reports},
  year = {2025},
  pmid = {40595262},
  doi = {10.1038/s41598-025-07989-1},
  url = {https://pubmed.ncbi.nlm.nih.gov/40595262/},
}

@article{pmid41398374,
  title = {Ganglioside sialylation modulates tau internalization and pathology spread.},
  author = {Li S, Chen Y, Song T, Liu D, Wu R, Yang X, Wu Q, Lei L, Yu X, Zhang J, Li L, Jiang Y, Gu J, Miao J, Gu JH, Shi J, Wu F, Liu F, Chu D},
  journal = {Molecular psychiatry},
  year = {2025},
  pmid = {41398374},
  doi = {10.1038/s41380-025-03394-2},
  url = {https://pubmed.ncbi.nlm.nih.gov/41398374/},
}

@article{pmid41430102,
  title = {Schwann cell Lrp1 deletion drives trigeminal neuron sensitization and orofacial pain by modulating mitochondrial function and TRPV1/TRPA1 activity.},
  author = {Gong Z, Zhang M, Liu N, Asam K, Martellucci S, Aouizerat B, Campana W, Ye Y},
  journal = {The journal of headache and pain},
  year = {2025},
  pmid = {41430102},
  doi = {10.1186/s10194-025-02250-6},
  url = {https://pubmed.ncbi.nlm.nih.gov/41430102/},
}

@article{pmid38906140,
  title = {Astrocytic LRP1 enables mitochondria transfer to neurons and mitigates brain ischemic stroke by suppressing ARF1 lactylation.},
  author = {Zhou J, Zhang L, Peng J, Zhang X, Zhang F, Wu Y, Huang A, Du F, Liao Y, He Y, Xie Y, Gu L, Kuang C, Ou W, Xie M, Tu T, Pang J, Zhang D, Guo K, Feng Y, Yin S, Cao Y, Li T, Jiang Y},
  journal = {Cell metabolism},
  year = {2024},
  pmid = {38906140},
  doi = {10.1016/j.cmet.2024.05.016},
  url = {https://pubmed.ncbi.nlm.nih.gov/38906140/},
}

@article{pmid39554169,
  title = {Mitochondrial NADK2-dependent NADPH controls Tau oligomer uptake in human neurons.},
  author = {Pardo E, Kim T, Wallrabe H, Zengeler KE, Sagar VK, Mingledorff G, Sun X, Periasamy A, Lukens JR, Bloom GS, Norambuena A},
  journal = {bioRxiv : the preprint server for biology},
  year = {2024},
  pmid = {39554169},
  doi = {10.1101/2024.10.31.621392},
  url = {https://pubmed.ncbi.nlm.nih.gov/39554169/},
}

@article{pmid39606238,
  title = {The role of neutrophils in tPA thrombolysis after stroke: a malicious troublemaker.},
  author = {Li Q, Ye J, Li Z, Xiao Q, Tan S, Hu B, Jin H},
  journal = {Frontiers in immunology},
  year = {2024},
  pmid = {39606238},
  doi = {10.3389/fimmu.2024.1477669},
  url = {https://pubmed.ncbi.nlm.nih.gov/39606238/},
}

@article{pmid36029232,
  title = {Editorial for “Corrected <scp>MRI</scp> Pulmonary Transit Time for Identification of Combined Pre and PostCapillary Pulmonary Hypertension in Patients With Left Heart Disease”},
  author = {Ricci Fabrizio; Khanji Mohammed Y; Garg Pankaj},
  journal = {Journal of Magnetic Resonance Imaging},
  year = {2023},
  pmid = {36029232},
  doi = {10.1002/jmri.28411},
}

@article{pmid36797420,
  title = {PFKFB2-mediated glycolysis promotes lactate-driven continual efferocytosis by macrophages.},
  author = {Schilperoort M, Ngai D, Katerelos M, Power DA, Tabas I},
  journal = {Nature metabolism},
  year = {2023},
  pmid = {36797420},
  doi = {10.1038/s42255-023-00736-8},
  url = {https://pubmed.ncbi.nlm.nih.gov/36797420/},
}

@article{pmid37198475,
  title = {Ancient gene linkages support ctenophores as sister to other animals.},
  author = {["Schultz D", "Haddock S", "Bredeson J", "Green R", "Simakov O", "Rokhsar D"]},
  journal = {Nature},
  year = {2023},
  pmid = {37198475},
  doi = {10.1038/s41586-023-05936-6},
}

@article{pmid37248301,
  title = {Pan-cancer T cell atlas links a cellular stress response state to immunotherapy resistance.},
  author = {["Chu Y", "Dai E", "Li Y", "Han G", "Pei G", "Ingram D", "Thakkar K", "Qin J", "Dang M", "Le X"]},
  journal = {Nature medicine},
  year = {2023},
  pmid = {37248301},
  doi = {10.1038/s41591-023-02371-y},
}

@article{pmid34260725,
  title = {Incidence of Chronic Obstructive Pulmonary Disease in People With Human Immunodeficiency Virus and Their Parents and Siblings in Denmark.},
  author = {["Ronit A", "Omland L", "Kronborg G", "Pedersen G", "Nielsen L", "Mohey R", "Wiese L", "Obel N", "Ahlstr\u00f6m M"]},
  journal = {The Journal of infectious diseases},
  year = {2022},
  pmid = {34260725},
  doi = {10.1093/infdis/jiab369},
}

@article{pmid35040015,
  title = {Heparan Sulfate Proteoglycans (HSPGs) Serve as the Mediator Between Monomeric Tau and Its Subsequent Intracellular ERK1/2 Pathway Activation.},
  author = {Song L, Oseid DE, Wells EA, Coaston T, Robinson AS},
  journal = {Journal of molecular neuroscience : MN},
  year = {2022},
  pmid = {35040015},
  doi = {10.1007/s12031-021-01943-2},
  url = {https://pubmed.ncbi.nlm.nih.gov/35040015/},
}

@article{pmid35209007,
  title = {Amyloidosis in Alzheimer's Disease: Pathogeny, Etiology, and Related Therapeutic Directions.},
  author = {Ma C, Hong F, Yang S},
  journal = {Molecules (Basel, Switzerland)},
  year = {2022},
  pmid = {35209007},
  doi = {10.3390/molecules27041210},
  url = {https://pubmed.ncbi.nlm.nih.gov/35209007/},
}

@article{pmid35346032,
  title = {Plastid retrograde regulation of miRNA expression in response to light stress.},
  author = {["Barczak-Brzy\u017cek A", "Brzy\u017cek G", "Koter M", "Siedlecka E", "Gawro\u0144ski P", "Filipecki M"]},
  journal = {BMC plant biology},
  year = {2022},
  pmid = {35346032},
  doi = {10.1186/s12870-022-03525-9},
}

@article{pmid36056345,
  title = {LRP1 is a neuronal receptor for α-synuclein uptake and spread.},
  author = {["Chen K", "Martens Y", "Meneses A", "Ryu D", "Lu W", "Raulin A", "Li F", "Zhao J", "Chen Y", "Jin Y"]},
  journal = {Molecular neurodegeneration},
  year = {2022},
  pmid = {36056345},
  doi = {10.1186/s13024-022-00560-w},
}

@article{pmid36097221,
  title = {Distinct cellular dynamics associated with response to CAR-T therapy for refractory B cell lymphoma.},
  author = {["Haradhvala N", "Leick M", "Maurer K", "Gohil S", "Larson R", "Yao N", "Gallagher K", "Katsis K", "Frigault M", "Southard J"]},
  journal = {Nature medicine},
  year = {2022},
  pmid = {36097221},
  doi = {10.1038/s41591-022-01959-0},
}

@article{pmid33172980,
  title = {Temporal Expectation Hastens Decision Onset But Does Not Affect Evidence Quality.},
  author = {["van den Brink R", "Murphy P", "Desender K", "de Ru N", "Nieuwenhuis S"]},
  journal = {The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year = {2021},
  pmid = {33172980},
  doi = {10.1523/JNEUROSCI.1103-20.2020},
}

@article{pmid33568819,
  title = {Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program.},
  author = {Taliun D, Harris DN, Kessler MD, Carlson J, Szpiech ZA, Torres R, Taliun SAG, Corvelo A, Gogarten SM, Kang HM, Pitsillides AN, LeFaive J, Lee SB, Tian X, Browning BL, Das S, Emde AK, Clarke WE, Loesch DP, Shetty AC, Blackwell TW, Smith AV, Wong Q, Liu X, Conomos MP, Bobo DM, Aguet F, Albert C, Alonso A, Ardlie KG},
  journal = {Nature},
  year = {2021},
  pmid = {33568819},
  doi = {10.1038/s41586-021-03205-y},
  url = {https://pubmed.ncbi.nlm.nih.gov/33568819/},
}

@article{pmid33930462,
  title = {Regulation of tau internalization, degradation, and seeding by LRP1 reveals multiple pathways for tau catabolism.},
  author = {["Cooper J", "Lathuiliere A", "Migliorini M", "Arai A", "Wani M", "Dujardin S", "Muratoglu S", "Hyman B", "Strickland D"]},
  journal = {The Journal of biological chemistry},
  year = {2021},
  pmid = {33930462},
  doi = {10.1016/j.jbc.2021.100715},
}

@article{pmid34282312,
  title = {Van der Waals heterostructures for spintronics and opto-spintronics.},
  author = {["Sierra J", "Fabian J", "Kawakami R", "Roche S", "Valenzuela S"]},
  journal = {Nature nanotechnology},
  year = {2021},
  pmid = {34282312},
  doi = {10.1038/s41565-021-00936-x},
}

@article{pmid34522589,
  title = {Evolution of blood-brain barrier in brain diseases and related systemic nanoscale brain-targeting drug delivery strategies.},
  author = {Han L, Jiang C},
  journal = {Acta pharmaceutica Sinica. B},
  year = {2021},
  pmid = {34522589},
  doi = {10.1016/j.apsb.2020.11.023},
  url = {https://pubmed.ncbi.nlm.nih.gov/34522589/},
}

@article{pmid34522589,
  title = {Evolution of blood-brain barrier in brain diseases and related systemic nanoscale brain-targeting drug delivery strategies.},
  author = {Han L, Jiang C},
  journal = {Acta Pharm Sin B},
  year = {2021},
  pmid = {34522589},
  doi = {doi: 10.1016/j.apsb.2020.11.023},
  url = {https://pubmed.ncbi.nlm.nih.gov/34522589/},
}

@article{pmid32296178,
  title = {LRP1 is a master regulator of tau uptake and spread.},
  author = {Rauch JN, Luna G, Guzman E, Audouard M, Challis C, Sibih YE, Leshuk C, Hernandez I, Wegmann S, Hyman BT, Gradinaru V, Kampmann M, Kosik KS},
  journal = {Nature},
  year = {2020},
  pmid = {32296178},
  doi = {10.1038/s41586-020-2156-5},
  url = {https://pubmed.ncbi.nlm.nih.gov/32296178/},
}

@article{pmid32826916,
  title = {Adaptive self-healing electronic epineurium for chronic bidirectional neural interfaces.},
  author = {Song KI, Seo H, Seong D, Kim S, Yu KJ, Kim YC, Kim J, Kwon SJ, Han HS, Youn I, Lee H, Son D},
  journal = {Nature communications},
  year = {2020},
  pmid = {32826916},
  doi = {10.1038/s41467-020-18025-3},
  url = {https://pubmed.ncbi.nlm.nih.gov/32826916/},
}

@article{pmid31653962,
  title = {Complex interactions between sperm viability and female fertility.},
  author = {Tourmente M, Archer CR, Hosken DJ},
  journal = {Scientific reports},
  year = {2019},
  pmid = {31653962},
  doi = {10.1038/s41598-019-51672-1},
  url = {https://pubmed.ncbi.nlm.nih.gov/31653962/},
}

@article{pmid29335385,
  title = {A Transradial Approach of Cardiac Catheterization for Patients on Dialysis.},
  author = {Kuno Toshiki; Hirano Keita; Imaeda Syohei; Hashimoto Kenji; Ryuzaki Toshinobu; Saito Tetsuya; Yamazaki Hiroyuki; Tabei Ryota; Kodaira Masaki; Numasawa Yohei},
  journal = {The Journal of invasive cardiology},
  year = {2018},
  pmid = {29335385},
  url = {https://pubmed.ncbi.nlm.nih.gov/29335385/},
}

@article{pmid30012813,
  title = {World Cancer Research Fund’s campaign helps people take control of cancer risk},
  author = {Kate Allen},
  journal = {BMJ (Clinical research ed.)},
  year = {2018},
  pmid = {30012813},
  doi = {10.1136/bmj.k3061},
}

@article{pmid30305742,
  title = {Perovskite light-emitting diodes based on spontaneously formed submicrometre-scale structures.},
  author = {Cao Y, Wang N, Tian H, Guo J, Wei Y, Chen H, Miao Y, Zou W, Pan K, He Y, Cao H, Ke Y, Xu M, Wang Y, Yang M, Du K, Fu Z, Kong D, Dai D, Jin Y, Li G, Li H, Peng Q, Wang J, Huang W},
  journal = {Nature},
  year = {2018},
  pmid = {30305742},
  doi = {10.1038/s41586-018-0576-2},
  url = {https://pubmed.ncbi.nlm.nih.gov/30305742/},
}

@article{pmid28687474,
  title = {Alfaxalone for maintenance of anaesthesia in ponies undergoing field castration: continuous infusion compared with intravenous boluses.},
  author = {["Deutsch J", "Ekiri A", "de Vries A"]},
  journal = {Veterinary anaesthesia and analgesia},
  year = {2017},
  pmid = {28687474},
  doi = {10.1016/j.vaa.2016.06.004},
}

@article{pmid28814781,
  title = {Association between LRP1 C766T polymorphism and Alzheimer's disease susceptibility: a meta-analysis.},
  author = {Wang Y, Liu S, Wang J, Zhang J, Hua Y, Li H, Tan H, Kuai B, Wang B, Sheng S},
  journal = {Scientific reports},
  year = {2017},
  pmid = {28814781},
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  url = {https://pubmed.ncbi.nlm.nih.gov/28814781/},
}

@article{pmid28916637,
  title = {Effect of increases in cardiac contractility on cerebral blood flow in humans.},
  author = {Ogoh S, Moralez G, Washio T, Sarma S, Hieda M, Romero SA, Cramer MN, Shibasaki M, Crandall CG},
  journal = {American journal of physiology. Heart and circulatory physiology},
  year = {2017},
  pmid = {28916637},
  doi = {10.1152/ajpheart.00287.2017},
  url = {https://pubmed.ncbi.nlm.nih.gov/28916637/},
}

@article{pmid27616661,
  title = {Epidemiology of Barrett's esophagus and esophageal adenocarcinoma in Spain. A unicentric study.},
  author = {["Arroyo-Mart\u00ednez Q", "Rodr\u00edguez-T\u00e9llez M", "Garc\u00eda-Escudero A", "Brugal-Medina J", "Gonz\u00e1lez-C\u00e1mpora R", "Caunedo \u00c1lvarez \u00c1"]},
  journal = {Revista espanola de enfermedades digestivas},
  year = {2016},
  pmid = {27616661},
  doi = {10.17235/reed.2016.4229/2016},
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@article{pmid21252304,
  title = {Gastrin-releasing peptide blockade as a broad-spectrum anti-inflammatory therapy for asthma.},
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  journal = {Proceedings of the National Academy of Sciences of the United States of America},
  year = {2011},
  pmid = {21252304},
  doi = {10.1073/pnas.1014792108},
}

@article{pmid17668063,
  title = {Mutations in the UBIAD1 gene, encoding a potential prenyltransferase, are causal for Schnyder crystalline corneal dystrophy.},
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  pmid = {12855673},
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@article{pmid10655062,
  title = {Limb-girdle muscular dystrophy type 2G is caused by mutations in the gene encoding the sarcomeric protein telethonin.},
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  journal = {Nature genetics},
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}