% Bibliography for hypothesis h-7693c291
% Title: RNA-Binding Competition Therapy for TDP-43 Cross-Seeding
% Generated: 2026-04-28T13:30:59Z

@article{pmid41570741,
  title = {ALS-related proteinopathies: From TDP-43 to mitochondrial proteinopathies.},
  author = {Genin EC, Paquis-Flucklinger V},
  journal = {Current opinion in neurobiology},
  year = {2026},
  pmid = {41570741},
  doi = {10.1016/j.conb.2025.103163},
  url = {https://pubmed.ncbi.nlm.nih.gov/41570741/},
}

@article{pmid41692368,
  title = {Refolding-assisted purification of native full-length TDP-43 compatible with BSL-2 safety regulations.},
  author = {Dehury S, Tiwari S, Los Rios P},
  journal = {Methods},
  year = {2026},
  pmid = {41692368},
  doi = {doi: 10.1016/j.ymeth.2026.02.009},
  url = {https://pubmed.ncbi.nlm.nih.gov/41692368/},
}

@article{pmid41854301,
  title = {Small heat shock proteins HspB1 and HspB5 differentially alter the condensation and aggregation of the TDP-43 low-complexity domain.},
  author = {Walker TB, Trowbridge JW, McMahon S, Marzano NR, Rice L et al.},
  journal = {Protein Sci},
  year = {2026},
  pmid = {41854301},
  doi = {doi: 10.1002/pro.70539},
  url = {https://pubmed.ncbi.nlm.nih.gov/41854301/},
}

@article{pmid41871974,
  title = {Structural and Mechanistic Heterogeneity of the Phase Separation and Aggregation of Full-Length TDP-43 is Governed by Environmental Conditions.},
  author = {Doke AA, Kirmire MS, Jha A, Jha SK},
  journal = {ACS Chem Neurosci},
  year = {2026},
  pmid = {41871974},
  doi = {doi: 10.1021/acschemneuro.5c01003},
  url = {https://pubmed.ncbi.nlm.nih.gov/41871974/},
}

@article{pmid41883703,
  title = {The Genetics of TDP-43 Type C Neurodegeneration: A Whole-Genome Sequencing Study and Literature Review.},
  author = {Nassan M, Ayala I, Sloan J, Bonfitto A, Stark B, Song S, Naymik M, Geula C, Gefen T, Barbieri E, Piras I, Mesulam MM, Huentelman M},
  journal = {Neurology. Genetics},
  year = {2026},
  pmid = {41883703},
  doi = {10.1212/NXG.0000000000200369},
  url = {https://pubmed.ncbi.nlm.nih.gov/41883703/},
}

@article{pmid40252666,
  title = {Amyotrophic lateral sclerosis caused by TARDBP mutations: from genetics to TDP-43 proteinopathy.},
  author = {Balendra R, Sreedharan J, Hallegger M, Luisier R, Lashuel HA, Gregory JM, Patani R},
  journal = {The Lancet. Neurology},
  year = {2025},
  pmid = {40252666},
  doi = {10.1016/S1474-4422(25)00109-7},
  url = {https://pubmed.ncbi.nlm.nih.gov/40252666/},
}

@article{pmid40633584,
  title = {Circular RNAs from the MAPT and TARDBP genes: Novel players in neurodegeneration?},
  author = {["Bagheri N", "Margvelani G", "Chiang T", "Nelson P", "Chuang T", "Stamm S"]},
  journal = {Neurochemistry international},
  year = {2025},
  pmid = {40633584},
  doi = {10.1016/j.neuint.2025.106019},
}

@article{pmid34916658,
  title = {TREM2 interacts with TDP-43 and mediates microglial neuroprotection against TDP-43-related neurodegeneration.},
  author = {Xie M, Liu YU, Zhao S, Zhang L, Bosco DB, Pang YP, Zhong J, Sheth U, Martens YA, Zhao N, Liu CC, Zhuang Y, Wang L, Dickson DW, Mattson MP, Bu G, Wu LJ},
  journal = {Nature neuroscience},
  year = {2022},
  pmid = {34916658},
  doi = {10.1038/s41593-021-00975-6},
  url = {https://pubmed.ncbi.nlm.nih.gov/34916658/},
}

@article{pmid35173339,
  title = {Magnetic control of tokamak plasmas through deep reinforcement learning.},
  author = {Degrave J, Felici F, Buchli J, Neunert M, Tracey B, Carpanese F, Ewalds T, Hafner R, Abdolmaleki A, de Las Casas D, Donner C, Fritz L, Galperti C, Huber A, Keeling J, Tsimpoukelli M, Kay J, Merle A, Moret JM, Noury S, Pesamosca F, Pfau D, Sauter O, Sommariva C, Coda S, Duval B, Fasoli A, Kohli P, Kavukcuoglu K, Hassabis D},
  journal = {Nature},
  year = {2022},
  pmid = {35173339},
  doi = {10.1038/s41586-021-04301-9},
  url = {https://pubmed.ncbi.nlm.nih.gov/35173339/},
}

@article{pmid33199879,
  title = {Cardiomyocyte-derived calcitonin regulates atrial fibrosis and AF.},
  author = {Fernández-Ruiz I},
  journal = {Nature reviews. Cardiology},
  year = {2021},
  pmid = {33199879},
  doi = {10.1038/s41569-020-00479-z},
  url = {https://pubmed.ncbi.nlm.nih.gov/33199879/},
}

@article{pmid33446423,
  title = {FUS and TDP-43 Phases in Health and Disease.},
  author = {["Portz Bede", "Lee Bo Lim", "Shorter James"]},
  journal = {Trends in biochemical sciences},
  year = {2021},
  pmid = {33446423},
  doi = {10.1101/2020.08.28.272377},
}

@article{pmid33446423,
  title = {FUS and TDP-43 Phases in Health and Disease.},
  author = {["Portz Bede", "Lee Bo Lim", "Shorter James"]},
  journal = {Trends in biochemical sciences},
  year = {2021},
  pmid = {33446423},
}

@article{pmid34380047,
  title = {TDP-43 condensation properties specify its RNA-binding and regulatory repertoire.},
  author = {Hallegger M, Chakrabarti AM, Lee FCY, Lee BL, Amalietti AG, Odeh HM, Copley KE, Rubien JD, Portz B, Kuret K, Huppertz I, Rau F, Patani R, Fawzi NL, Shorter J, Luscombe NM, Ule J},
  journal = {Cell},
  year = {2021},
  pmid = {34380047},
  doi = {10.1016/j.cell.2021.07.018},
  url = {https://pubmed.ncbi.nlm.nih.gov/34380047/},
}

@article{pmid34469734,
  title = {SMS2 deficiency impairs PKCδ-regulated B cell tolerance in the germinal center.},
  author = {Ou P, Stanek A, Huan Z, Roman CAJ, Huan C},
  journal = {Cell reports},
  year = {2021},
  pmid = {34469734},
  doi = {10.1016/j.celrep.2021.109624},
  url = {https://pubmed.ncbi.nlm.nih.gov/34469734/},
}

@article{pmid34930382,
  title = {TDP-43 Pathology in Alzheimer's Disease.},
  author = {Meneses A, Koga S, O'Leary J, Dickson DW, Bu G, Zhao N},
  journal = {Mol Neurodegener},
  year = {2021},
  pmid = {34930382},
  doi = {10.1186/s13024-021-00503-x},
  url = {https://pubmed.ncbi.nlm.nih.gov/34930382},
}

@article{pmid32203399,
  title = {Protein transmission in neurodegenerative disease.},
  author = {Peng C, Trojanowski JQ, Lee VM},
  journal = {Nat Rev Neurol},
  year = {2020},
  pmid = {32203399},
  doi = {10.1038/s41582-020-0333-7},
  url = {https://pubmed.ncbi.nlm.nih.gov/32203399},
}

@article{pmid33031745,
  title = {TDP-43 Triggers Mitochondrial DNA Release via mPTP to Activate cGAS/STING in ALS.},
  author = {Yu CH, Davidson S, Harapas CR, Hilton JB, Mlodzianoski MJ, Laohamonthonkul P, Louis C, Low RRJ, Moecking J, De Nardo D},
  journal = {Cell},
  year = {2020},
  pmid = {33031745},
  doi = {10.1016/j.cell.2020.09.020},
  url = {https://pubmed.ncbi.nlm.nih.gov/33031745},
}

@article{pmid33031745,
  title = {TDP-43 Triggers Mitochondrial DNA Release via mPTP to Activate cGAS/STING in ALS.},
  author = {Yu CH, Davidson S, Harapas CR, Hilton JB, Mlodzianoski MJ, Laohamonthonkul P, Louis C, Low RRJ, Moecking J, De Nardo D},
  journal = {Cell},
  year = {2020},
  pmid = {33031745},
}

@article{pmid30643298,
  title = {Premature polyadenylation-mediated loss of stathmin-2 is a hallmark of TDP-43-dependent neurodegeneration.},
  author = {Melamed Ze'ev; López-Erauskin Jone; Baughn Michael W; Zhang Ouyang; Drenner Kevin; Sun Ying; Freyermuth Fernande; McMahon Moira A; Beccari Melinda S; Artates Jon W; Ohkubo Takuya; Rodriguez Maria; Lin Nianwei; Wu Dongmei; Bennett C Frank; Rigo Frank; Da Cruz Sandrine; Ravits John; Lagier-Tourenne Clotilde; Cleveland Don W},
  journal = {Nature neuroscience},
  year = {2019},
  pmid = {30643298},
  doi = {10.1038/s41593-018-0293-z},
}

@article{pmid30643298,
  title = {Premature polyadenylation-mediated loss of stathmin-2 is a hallmark of TDP-43-dependent neurodegeneration.},
  author = {Melamed Z, López-Erauskin J, Baughn MW, Zhang O, Drenner K, Sun Y, Freyermuth F, McMahon MA, Beccari MS, Artates JW, Ohkubo T, Rodriguez M, Lin N, Wu D, Bennett CF, Rigo F, Da Cruz S, Ravits J, Lagier-Tourenne C, Cleveland DW},
  journal = {Nature neuroscience},
  year = {2019},
  pmid = {30643298},
  doi = {10.1038/s41593-018-0293-z},
  url = {https://pubmed.ncbi.nlm.nih.gov/30643298/},
}

@article{pmid26250685,
  title = {TDP-43 repression of nonconserved cryptic exons is compromised in ALS-FTD.},
  author = {["Ling Jonathan P", "Pletnikova Olga", "Troncoso Juan C", "Wong Philip C"]},
  journal = {Science (New York, N.Y.)},
  year = {2015},
  pmid = {26250685},
  doi = {10.1126/science.aab0983},
}

@article{pmid21358640,
  title = {Characterizing the RNA targets and position-dependent splicing regulation by TDP-43.},
  author = {Tollervey JR, Curk T, Rogelj B, Briese M, Cereda M, Kayikci M, König J, Hortobágyi T, Nishimura AL, Zupunski V, Patani R, Chandran S, Rot G, Zupan B, Shaw CE, Ule J},
  journal = {Nature neuroscience},
  year = {2011},
  pmid = {21358640},
  doi = {10.1038/nn.2778},
  url = {https://pubmed.ncbi.nlm.nih.gov/21358640/},
}

@article{pmid19192301,
  title = {Amyotrophic lateral sclerosis.},
  author = {Wijesekera LC, Leigh PN},
  journal = {Orphanet journal of rare diseases},
  year = {2009},
  pmid = {19192301},
  doi = {10.1186/1750-1172-4-3},
  url = {https://pubmed.ncbi.nlm.nih.gov/19192301/},
}