% Bibliography for hypothesis h-782b40b1
% Title: Optogenetic Microglial Deactivation via Engineered Inhibitory Opsins
% Generated: 2026-06-07T17:31:25Z

@article{pmid41564496,
  title = {Spatiotemporal dynamic regulation of the CX3CL1-CX3CR1 axis: A double-edged sword in the tumor immune microenvironment and new strategies for precision therapy.},
  author = {Liang J, Zhu W, Pan R, Wei S, Zhang S et al.},
  journal = {Cytokine Growth Factor Rev},
  year = {2026},
  pmid = {41564496},
  doi = {doi: 10.1016/j.cytogfr.2026.01.006},
  url = {https://pubmed.ncbi.nlm.nih.gov/41564496/},
}

@article{pmid39908361,
  title = {Reducing microglial lipid load enhances β amyloid phagocytosis in an Alzheimer's disease mouse model.},
  author = {Wu X, Miller JA, Lee BTK, Wang Y, Ruedl C},
  journal = {Sci Adv},
  year = {2025},
  pmid = {39908361},
  doi = {10.1126/sciadv.adq6038},
  url = {https://pubmed.ncbi.nlm.nih.gov/39908361},
}

@article{pmid37465997,
  title = {Fractalkine Enhances Hematoma Resolution and Improves Neurological Function via CX3CR1/AMPK/PPARγ Pathway After GMH.},
  author = {Chen X, He X, Xu F, Xu N, Sharifi NH, Zhang P, Flores JJ, Wu L, He Q, Kanamaru H},
  journal = {Stroke},
  year = {2023},
  pmid = {37465997},
  doi = {10.1161/STROKEAHA.123.043005},
  url = {https://pubmed.ncbi.nlm.nih.gov/37465997},
}

@article{pmid34492237,
  title = {CX3CL1/CX3CR1 signaling targets for the treatment of neurodegenerative diseases.},
  author = {Subbarayan MS, Joly-Amado A, Bickford PC, Nash KR},
  journal = {Pharmacol Ther},
  year = {2022},
  pmid = {34492237},
  doi = {10.1016/j.pharmthera.2021.107989},
  url = {https://pubmed.ncbi.nlm.nih.gov/34492237},
}

@article{pmid35045285,
  title = {Cx3Cr1-Cre induction leads to microglial activation and IFN-1 signaling caused by DNA damage in early postnatal brain.},
  author = {Sahasrabuddhe V, Ghosh HS},
  journal = {Cell reports},
  year = {2022},
  pmid = {35045285},
  doi = {10.1016/j.celrep.2021.110252},
  url = {https://pubmed.ncbi.nlm.nih.gov/35045285/},
}

@article{pmid35642214,
  title = {Microglia-Mediated Neuroinflammation: A Potential Target for the Treatment of Cardiovascular Diseases.},
  author = {Wang M, Pan W, Xu Y, Zhang J, Wan J, Jiang H},
  journal = {J Inflamm Res},
  year = {2022},
  pmid = {35642214},
  doi = {10.2147/JIR.S350109},
  url = {https://pubmed.ncbi.nlm.nih.gov/35642214},
}

@article{pmid31168067,
  title = {Lower excitatory synaptic gene expression in orbitofrontal cortex and striatum in an initial study of subjects with obsessive compulsive disorder.},
  author = {["Piantadosi S", "Chamberlain B", "Glausier J", "Lewis D", "Ahmari S"]},
  journal = {Molecular psychiatry},
  year = {2021},
  pmid = {31168067},
  doi = {10.1038/s41380-019-0431-3},
}

@article{pmid33981047,
  title = {High-performance brain-to-text communication via handwriting.},
  author = {["Willett F", "Avansino D", "Hochberg L", "Henderson J", "Shenoy K"]},
  journal = {Nature},
  year = {2021},
  pmid = {33981047},
  doi = {10.1038/s41586-021-03506-2},
}

@article{pmid33986261,
  title = {Cellular connectomes as arbiters of local circuit models in the cerebral cortex.},
  author = {["Klinger E", "Motta A", "Marr C", "Theis F", "Helmstaedter M"]},
  journal = {Nature communications},
  year = {2021},
  pmid = {33986261},
  doi = {10.1038/s41467-021-22856-z},
}

@article{pmid31474370,
  title = {Single-Cell Analysis of Crohn's Disease Lesions Identifies a Pathogenic Cellular Module Associated with Resistance to Anti-TNF Therapy.},
  author = {["Martin J", "Chang C", "Boschetti G", "Ungaro R", "Giri M", "Grout J", "Gettler K", "Chuang L", "Nayar S", "Greenstein A"]},
  journal = {Cell},
  year = {2019},
  pmid = {31474370},
  doi = {10.1016/j.cell.2019.08.008},
}

@article{pmid31675180,
  title = {De novo NSF mutations cause early infantile epileptic encephalopathy.},
  author = {["Suzuki H", "Yoshida T", "Morisada N", "Uehara T", "Kosaki K", "Sato K", "Matsubara K", "Takano-Shimizu T", "Takenouchi T"]},
  journal = {Annals of clinical and translational neurology},
  year = {2019},
  pmid = {31675180},
  doi = {10.1002/acn3.50917},
}

@article{pmid29527013,
  title = {Trabeculectomy training in England: are we safe at training? Two year surgical outcomes.},
  author = {["Walkden A", "Huxtable J", "Senior M", "Lee H", "Naylor S", "Turner S", "Ivanova K", "Koppens J", "Todd B", "Macleod A"]},
  journal = {Eye (London, England)},
  year = {2018},
  pmid = {29527013},
  doi = {10.1038/s41433-018-0059-6},
}

@article{pmid30258232,
  title = {Subcycle observation of lightwave-driven Dirac currents in a topological surface band.},
  author = {["Reimann J", "Schlauderer S", "Schmid C", "Langer F", "Baierl S", "Kokh K", "Tereshchenko O", "Kimura A", "Lange C", "G\u00fcdde J"]},
  journal = {Nature},
  year = {2018},
  pmid = {30258232},
  doi = {10.1038/s41586-018-0544-x},
}

@article{pmid30258234,
  title = {Microglia in neurodegeneration.},
  author = {Hickman S, Izzy S, Sen P, Morsett L, El Khoury J},
  journal = {Nat Neurosci},
  year = {2018},
  pmid = {30258234},
  doi = {10.1038/s41593-018-0242-x},
  url = {https://pubmed.ncbi.nlm.nih.gov/30258234},
}

@article{pmid30258234,
  title = {Microglia in neurodegeneration.},
  author = {Hickman S, Izzy S, Sen P, Morsett L, El Khoury J},
  journal = {Nat Neurosci},
  year = {2018},
  pmid = {30258234},
  doi = {doi: 10.1038/s41593-018-0242-x},
  url = {https://pubmed.ncbi.nlm.nih.gov/30258234/},
}

@article{pmid32076275,
  title = {Strategy for making safer opioids bolstered.},
  author = {Majumdar Susruta; Devi Lakshmi A},
  journal = {Nature},
  year = {2018},
  pmid = {32076275},
  doi = {10.1038/d41586-018-00045-1},
}

@article{pmid28528700,
  title = {Directed Differentiation of Human Pluripotent Stem Cells to Microglia.},
  author = {Douvaras P, Sun B, Wang M, Kruglikov I, Lallos G, Zimmer M, Terrenoire C, Zhang B, Gandy S, Schadt E, Freytes DO, Noggle S, Fossati V},
  journal = {Stem cell reports},
  year = {2017},
  pmid = {28528700},
  doi = {10.1016/j.stemcr.2017.04.023},
  url = {https://pubmed.ncbi.nlm.nih.gov/28528700/},
}

@article{pmid27045594,
  title = {Distinct forms of synaptic inhibition and neuromodulation regulate calretinin-positive neuron excitability in the spinal cord dorsal horn.},
  author = {["Smith K", "Boyle K", "Mustapa M", "Jobling P", "Callister R", "Hughes D", "Graham B"]},
  journal = {Neuroscience},
  year = {2016},
  pmid = {27045594},
  doi = {10.1016/j.neuroscience.2016.03.058},
}

@article{pmid26390154,
  title = {Architecture of the mammalian mechanosensitive Piezo1 channel.},
  author = {["Ge J", "Li W", "Zhao Q", "Li N", "Chen M", "Zhi P", "Li R", "Gao N", "Xiao B", "Yang M"]},
  journal = {Nature},
  year = {2015},
  pmid = {26390154},
  doi = {10.1038/nature15247},
}