% Bibliography for hypothesis h-7e846ceb
% Title: Glycine-Rich Domain Competitive Inhibition
% Generated: 2026-06-08T10:38:34Z

@article{pmid41512823,
  title = {Defining RNA oligonucleotides that reverse deleterious phase transitions of RNA-binding proteins with prion-like domains.},
  author = {["Guo L", "Mann J", "Mauna J", "Copley K", "Wang H", "Rubien J", "Bergmann C", "Carey J", "Merjane J", "Ngo M"]},
  journal = {Molecular cell},
  year = {2026},
  pmid = {41512823},
  doi = {10.1016/j.molcel.2025.12.009},
}

@article{pmid41609580,
  title = {Elucidation of Molecular Mechanisms of Lipid-Altered Cytotoxicity of TDP-43 Fibrils.},
  author = {["Purvinsh Y", "Matveyenka M", "Kurouski D"]},
  journal = {ACS chemical neuroscience},
  year = {2026},
  pmid = {41609580},
  doi = {10.1021/acschemneuro.5c00934},
}

@article{pmid41654570,
  title = {Direct observation and quantification of single nanocondensates of the low complexity domain of TDP-43.},
  author = {["Houx J", "Cussac J", "Copie T", "Gambin Y", "Sierecki E"]},
  journal = {Nature communications},
  year = {2026},
  pmid = {41654570},
  doi = {10.1038/s41467-026-69024-9},
}

@article{pmid41690263,
  title = {Small heat shock protein HSPB8 interacts with a pre-fibrillar TDP43 low complexity domain species to delay fibril formation.},
  author = {["Jami K", "Corbett K", "Farb D", "Osumi K", "Shafer C", "Criscione S", "Murray D"]},
  journal = {Biophysical chemistry},
  year = {2026},
  pmid = {41690263},
  doi = {10.1016/j.bpc.2026.107590},
}

@article{pmid41883703,
  title = {The Genetics of TDP-43 Type C Neurodegeneration: A Whole-Genome Sequencing Study and Literature Review.},
  author = {Nassan M, Ayala I, Sloan J, Bonfitto A, Stark B, Song S, Naymik M, Geula C, Gefen T, Barbieri E, Piras I, Mesulam MM, Huentelman M},
  journal = {Neurology. Genetics},
  year = {2026},
  pmid = {41883703},
  doi = {10.1212/NXG.0000000000200369},
  url = {https://pubmed.ncbi.nlm.nih.gov/41883703/},
}

@article{pmid41890274,
  title = {Excitotoxicity in amyotrophic lateral sclerosis: a key pathogenic mechanism.},
  author = {Silva-Hucha S, Hernández RG, Baena-López D, Fernández de Sevilla ME, Paradas C, Morcuende S},
  journal = {Brain communications},
  year = {2026},
  pmid = {41890274},
  doi = {10.1093/braincomms/fcag098},
  url = {https://pubmed.ncbi.nlm.nih.gov/41890274/},
}

@article{pmid41890591,
  title = {Axonal transport impairment as an upstream mechanism in amyotrophic lateral sclerosis pathogenesis.},
  author = {Gabbay U},
  journal = {Frontiers in neuroscience},
  year = {2026},
  pmid = {41890591},
  doi = {10.3389/fnins.2026.1802313},
  url = {https://pubmed.ncbi.nlm.nih.gov/41890591/},
}

@article{pmid41897327,
  title = {Selective Silencing of TDP-43 P. G376D Mutation Reverses Key Amyotrophic Lateral Sclerosis-Related Cellular Deficits.},
  author = {Romano R, Ruotolo G, Perrone F, Tomaselli S, Mazzoni M, Spataro R, Conforti FL, Rosati J, Bucci C},
  journal = {Biomolecules},
  year = {2026},
  pmid = {41897327},
  doi = {10.3390/biom16030393},
  url = {https://pubmed.ncbi.nlm.nih.gov/41897327/},
}

@article{pmid41900026,
  title = {Chemical and Molecular Strategies in Restoring Autophagic Flux in TDP-43 Proteinopathy.},
  author = {Jamerlan A, Hulme J},
  journal = {Molecules (Basel, Switzerland)},
  year = {2026},
  pmid = {41900026},
  doi = {10.3390/molecules31060924},
  url = {https://pubmed.ncbi.nlm.nih.gov/41900026/},
}

@article{pmid41397930,
  title = {Inertial Agitation in an NMR Magnet: Real-Time Monitoring of Protein Aggregation at High Resolution.},
  author = {["Lee J", "Jung S", "Yu S", "Park S", "Kim N", "Lee J"]},
  journal = {Journal of the American Chemical Society},
  year = {2025},
  pmid = {41397930},
  doi = {10.1021/jacs.5c16918},
}

@article{pmid38277467,
  title = {Mis-spliced transcripts generate de novo proteins in TDP-43-related ALS/FTD.},
  author = {Seddighi S, Qi YA, Brown AL, Wilkins OG, Bereda C, Belair C, Zhang YJ, Prudencio M, Keuss MJ, Khandeshi A, Pickles S, Kargbo-Hill SE, Hawrot J, Ramos DM, Yuan H, Roberts J, Sacramento EK, Shah SI, Nalls MA, Colón-Mercado JM, Reyes JF, Ryan VH, Nelson MP, Cook CN, Li Z, Screven L, Kwan JY, Mehta PR, Zanovello M, Hallegger M},
  journal = {Science translational medicine},
  year = {2024},
  pmid = {38277467},
  doi = {10.1126/scitranslmed.adg7162},
  url = {https://pubmed.ncbi.nlm.nih.gov/38277467/},
}

@article{pmid36754049,
  title = {PIKFYVE inhibition mitigates disease in models of diverse forms of ALS.},
  author = {Hung ST, Linares GR, Chang WH, Eoh Y, Krishnan G, Mendonca S, Hong S, Shi Y, Santana M, Kueth C},
  journal = {Cell},
  year = {2023},
  pmid = {36754049},
  doi = {10.1016/j.cell.2023.01.005},
  url = {https://pubmed.ncbi.nlm.nih.gov/36754049},
}

@article{pmid36861818,
  title = {N protein of PEDV plays chess game with host proteins by selective autophagy.},
  author = {Zhai X, Kong N, Zhang Y, Song Y, Qin W, Yang X, Ye C, Ye M, Tong W, Liu C},
  journal = {Autophagy},
  year = {2023},
  pmid = {36861818},
  doi = {10.1080/15548627.2023.2181615},
  url = {https://pubmed.ncbi.nlm.nih.gov/36861818},
}

@article{pmid34057020,
  title = {Autophagy and ALS: mechanistic insights and therapeutic implications.},
  author = {Chua JP, De Calbiac H, Kabashi E, Barmada SJ},
  journal = {Autophagy},
  year = {2022},
  pmid = {34057020},
  doi = {10.1080/15548627.2021.1926656},
  url = {https://pubmed.ncbi.nlm.nih.gov/34057020},
}

@article{pmid34930382,
  title = {TDP-43 Pathology in Alzheimer's Disease.},
  author = {Meneses A, Koga S, O'Leary J, Dickson DW, Bu G, Zhao N},
  journal = {Mol Neurodegener},
  year = {2021},
  pmid = {34930382},
  doi = {10.1186/s13024-021-00503-x},
  url = {https://pubmed.ncbi.nlm.nih.gov/34930382},
}

@article{pmid32203399,
  title = {Protein transmission in neurodegenerative disease.},
  author = {Peng C, Trojanowski JQ, Lee VM},
  journal = {Nat Rev Neurol},
  year = {2020},
  pmid = {32203399},
  doi = {10.1038/s41582-020-0333-7},
  url = {https://pubmed.ncbi.nlm.nih.gov/32203399},
}

@article{pmid32878979,
  title = {C9orf72 poly(GR) aggregation induces TDP-43 proteinopathy.},
  author = {Cook CN, Wu Y, Odeh HM, Gendron TF, Jansen-West K, Del Rosso G, Yue M, Jiang P, Gomes E, Tong J, Daughrity LM, Avendano NM, Castanedes-Casey M, Shao W, Oskarsson B, Tomassy GS, McCampbell A, Rigo F, Dickson DW, Shorter J, Zhang YJ, Petrucelli L},
  journal = {Science translational medicine},
  year = {2020},
  pmid = {32878979},
  doi = {10.1126/scitranslmed.abb3774},
  url = {https://pubmed.ncbi.nlm.nih.gov/32878979/},
}

@article{pmid33031745,
  title = {TDP-43 Triggers Mitochondrial DNA Release via mPTP to Activate cGAS/STING in ALS.},
  author = {Yu CH, Davidson S, Harapas CR, Hilton JB, Mlodzianoski MJ, Laohamonthonkul P, Louis C, Low RRJ, Moecking J, De Nardo D},
  journal = {Cell},
  year = {2020},
  pmid = {33031745},
  doi = {10.1016/j.cell.2020.09.020},
  url = {https://pubmed.ncbi.nlm.nih.gov/33031745},
}

@article{pmid33031745,
  title = {TDP-43 Triggers Mitochondrial DNA Release via mPTP to Activate cGAS/STING in ALS.},
  author = {Yu CH, Davidson S, Harapas CR, Hilton JB, Mlodzianoski MJ, Laohamonthonkul P, Louis C, Low RRJ, Moecking J, De Nardo D},
  journal = {Cell},
  year = {2020},
  pmid = {33031745},
}

@article{pmid33177049,
  title = {TDP-43 proteinopathies: a new wave of neurodegenerative diseases.},
  author = {de Boer EMJ, Orie VK, Williams T, Baker MR, De Oliveira HM, Polvikoski T, Silsby M, Menon P, van den Bos M, Halliday GM, van den Berg LH, Van Den Bosch L, van Damme P, Kiernan MC, van Es MA, Vucic S},
  journal = {Journal of neurology, neurosurgery, and psychiatry},
  year = {2020},
  pmid = {33177049},
  doi = {10.1136/jnnp-2020-322983},
  url = {https://pubmed.ncbi.nlm.nih.gov/33177049/},
}

@article{pmid30335591,
  title = {Trehalose induces autophagy via lysosomal-mediated TFEB activation in models of motoneuron degeneration.},
  author = {Rusmini P, Cortese K, Crippa V, Cristofani R, Cicardi ME, Ferrari V, Vezzoli G, Tedesco B, Meroni M, Messi E},
  journal = {Autophagy},
  year = {2019},
  pmid = {30335591},
  doi = {10.1080/15548627.2018.1535292},
  url = {https://pubmed.ncbi.nlm.nih.gov/30335591},
}

@article{pmid26406374,
  title = {Phase separation by low complexity domains promotes stress granule assembly and drives pathological fibrillization.},
  author = {Molliex A, Temirov J, Lee J, Coughlin M, Kanagaraj AP, Kim HJ, Mittag T, Taylor JP},
  journal = {Cell},
  year = {2015},
  pmid = {26406374},
  doi = {10.1016/j.cell.2015.09.015},
  url = {https://pubmed.ncbi.nlm.nih.gov/26406374/},
}

@article{pmid23755159,
  title = {Credibility analysis of putative disease-causing genes using bioinformatics.},
  author = {["Abel O", "Powell J", "Andersen P", "Al-Chalabi A"]},
  journal = {PloS one},
  year = {2013},
  pmid = {23755159},
  doi = {10.1371/journal.pone.0064899},
}

@article{pmid19192301,
  title = {Amyotrophic lateral sclerosis.},
  author = {Wijesekera LC, Leigh PN},
  journal = {Orphanet journal of rare diseases},
  year = {2009},
  pmid = {19192301},
  doi = {10.1186/1750-1172-4-3},
  url = {https://pubmed.ncbi.nlm.nih.gov/19192301/},
}