% Bibliography for hypothesis h-8597755b
% Title: Orexin-Microglia Modulation Therapy
% Generated: 2026-06-08T18:00:44Z

@article{pmid41256182,
  title = {Sex-Specific Effects of Hypocretin Receptor Signaling in Corticotropin-Releasing Factor Neurons on Alcohol Drinking, Anxiety, and Extended Amygdala Neuronal Excitability.},
  author = {["Ma Y", "Sardar H", "Benabou M", "Yu A", "Morningstar A", "Fajardo R", "Kandil I", "Rogers E", "Vassalli A", "Kauer J"]},
  journal = {Biological psychiatry global open science},
  year = {2026},
  pmid = {41256182},
  doi = {10.1016/j.bpsgos.2025.100617},
}

@article{pmid41359331,
  title = {Effects of Oveporexton, an Orexin Receptor 2-Selective Agonist, on Cognition in Narcolepsy Type 1: A Secondary Analysis of a Randomized Clinical Trial.},
  author = {["Lammers G", "Plazzi G", "Mignot E", "Pizza F", "Dauvilliers Y", "Barateau L", "Maruff P", "Scammell T", "Latzman R", "Naylor M"]},
  journal = {JAMA neurology},
  year = {2026},
  pmid = {41359331},
  doi = {10.1001/jamaneurol.2025.4825},
}

@article{pmid41622624,
  title = {Estimation of the Orexin Receptor Occupancy From Human Plasma Pharmacokinetics of Vornorexant, a Novel Dual Orexin 1/2 Receptor Antagonist for the Treatment of Insomnia.},
  author = {["Kamigaso S", "Konno Y", "Hikichi H", "Kambe D", "Mano Y", "Tokumaru Y", "Mori H", "Yamasaki H", "Chino Y", "Hachiuma K"]},
  journal = {Pharmacology research & perspectives},
  year = {2026},
  pmid = {41622624},
  doi = {10.1002/prp2.70217},
}

@article{pmid41648545,
  title = {Prioritizing Neuroactive Ligands Using Motif-Guided Virtual Discovery and Zebrafish Profiling.},
  author = {["Ginsparg A", "Martinez J", "Patel I", "Buton A", "Lee L", "Sarwar R", "Moretti R", "Puig S", "Thyme S"]},
  journal = {bioRxiv : the preprint server for biology},
  year = {2026},
  pmid = {41648545},
  doi = {10.64898/2026.01.15.699747},
}

@article{pmid41787892,
  title = {Association between genetic polymorphisms in circadian cycle genes (},
  author = {["Alves R", "da Cunha L", "Albuquerque A", "de Souza R", "de Miranda D", "Alvim-Soares A", "de Marco L", "Bastos-Rodrigues L"]},
  journal = {Chronobiology international},
  year = {2026},
  pmid = {41787892},
  doi = {10.1080/07420528.2026.2641008},
}

@article{pmid41834039,
  title = {Social defeat stress responses in the stress alternative model are dependent on sex and anterior basolateral amygdala orexin 2 receptors.},
  author = {["Yaeger J", "John M", "Ledesma L", "Greschke T", "Gale J", "Meyer L", "Brummels R", "Korzan W", "Waters R", "Summers C"]},
  journal = {Biology of sex differences},
  year = {2026},
  pmid = {41834039},
  doi = {10.1186/s13293-026-00858-0},
}

@article{pmid41870530,
  title = {Dual hypocretin receptor antagonists enhance sleep and nursing behavior in lactating rats.},
  author = {["Rivas M", "Pe\u00f1a F", "Prota C", "Carrera-Ca\u00f1as C", "Garz\u00f3n M", "Torterolo P", "Benedetto L"]},
  journal = {Psychopharmacology},
  year = {2026},
  pmid = {41870530},
  doi = {10.1007/s00213-026-07049-0},
}

@article{pmid40514007,
  title = {Acute carbamoylated erythropoietin reduces social stress-induced anxiety and depression-related behaviors.},
  author = {Yaeger JDW, John MM, Ledesma LJ, Krupp KT, Booth CD, Jones NT, Valiño A, Popp N, Sathyanesan M, Newton SS, Summers CH},
  journal = {Neuropharmacology},
  year = {2025},
  pmid = {40514007},
  doi = {10.1016/j.neuropharm.2025.110558},
  url = {https://pubmed.ncbi.nlm.nih.gov/40514007/},
}

@article{pmid41383480,
  title = {Signal transduction, dimerization, and therapeutic targeting of Orexin and receptor systems.},
  author = {Zhang S, Wang P, Ji B, Shao Y, Hou S et al.},
  journal = {Front Pharmacol},
  year = {2025},
  pmid = {41383480},
  doi = {doi: 10.3389/fphar.2025.1697406},
  url = {https://pubmed.ncbi.nlm.nih.gov/41383480/},
}

@article{pmid40599447,
  title = {Involvement of the Orexin 1 and 2 Receptors in Nucleus Incertus (NI) on Modulation of Spatial Reference Memory in the Morris Water Maze.},
  author = {Eslami F, Akbari E, Babapour V, Zendehdel M},
  journal = {Archives of Razi Institute},
  year = {2024},
  pmid = {40599447},
  doi = {10.32592/ARI.2024.79.6.1207},
  url = {https://pubmed.ncbi.nlm.nih.gov/40599447/},
}

@article{pmid36526025,
  title = {Hypothalamic molecular correlates of photoperiod-induced spring migration in intact and castrated male redheaded buntings.},
  author = {Sharma A, Tripathi V, Kumar V},
  journal = {Molecular and cellular endocrinology},
  year = {2023},
  pmid = {36526025},
  doi = {10.1016/j.mce.2022.111829},
  url = {https://pubmed.ncbi.nlm.nih.gov/36526025/},
}

@article{pmid33582153,
  title = {Orexin-A differentially modulates inhibitory and excitatory synaptic transmission in rat inner retina.},
  author = {Ruan HZ, Wang LQ, Yuan F, Weng SJ, Zhong YM},
  journal = {Neuropharmacology},
  year = {2021},
  pmid = {33582153},
  doi = {10.1016/j.neuropharm.2021.108492},
  url = {https://pubmed.ncbi.nlm.nih.gov/33582153/},
}

@article{pmid29031502,
  title = {Low Rates of Gastrointestinal and Non-Gastrointestinal Complications for Screening or Surveillance Colonoscopies in a Population-Based Study.},
  author = {Wang L, Mannalithara A, Singh G, Ladabaum U},
  journal = {Gastroenterology},
  year = {2018},
  pmid = {29031502},
  doi = {10.1053/j.gastro.2017.10.006},
  url = {https://pubmed.ncbi.nlm.nih.gov/29031502},
}

@article{pmid29705705,
  title = {Modulation by orexin A of spontaneous excitatory and inhibitory transmission in adult rat spinal substantia gelatinosa neurons.},
  author = {Wang C, Fujita T, Kumamoto E},
  journal = {Biochemical and biophysical research communications},
  year = {2018},
  pmid = {29705705},
  doi = {10.1016/j.bbrc.2018.04.182},
  url = {https://pubmed.ncbi.nlm.nih.gov/29705705/},
}

@article{pmid28336668,
  title = {Lysosomal cholesterol activates mTORC1 via an SLC38A9-Niemann-Pick C1 signaling complex.},
  author = {Castellano BM, Thelen AM, Moldavski O, Feltes M, van der Welle RE, Mydock-McGrane L, Jiang X, van Eijkeren RJ, Davis OB, Louie SM},
  journal = {Science},
  year = {2017},
  pmid = {28336668},
  doi = {10.1126/science.aag1417},
  url = {https://pubmed.ncbi.nlm.nih.gov/28336668},
}

@article{pmid29031901,
  title = {Als and Ftd: Insights into the disease mechanisms and therapeutic targets.},
  author = {Liscic RM},
  journal = {Eur J Pharmacol},
  year = {2017},
  pmid = {29031901},
  doi = {10.1016/j.ejphar.2017.10.012},
  url = {https://pubmed.ncbi.nlm.nih.gov/29031901},
}

@article{pmid27031682,
  title = {Mechanistic insights into influenza vaccine-associated narcolepsy.},
  author = {Ahmed SS, Steinman L},
  journal = {Human vaccines & immunotherapeutics},
  year = {2016},
  pmid = {27031682},
  doi = {10.1080/21645515.2016.1171439},
  url = {https://pubmed.ncbi.nlm.nih.gov/27031682/},
}

@article{pmid27309819,
  title = {Defining the consequences of genetic variation on a proteome-wide scale.},
  author = {Chick JM, Munger SC, Simecek P, Huttlin EL, Choi K, Gatti DM, Raghupathy N, Svenson KL, Churchill GA, Gygi SP},
  journal = {Nature},
  year = {2016},
  pmid = {27309819},
  doi = {10.1038/nature18270},
  url = {https://pubmed.ncbi.nlm.nih.gov/27309819},
}

@article{pmid25448707,
  title = {A comparative examination of thrombocyte/platelet immunity.},
  author = {F Ferdous, T R Scott},
  journal = {Immunology letters},
  year = {2015},
  pmid = {25448707},
  doi = {10.1016/j.imlet.2014.11.010},
  url = {https://pubmed.ncbi.nlm.nih.gov/25448707},
}

@article{pmid25307057,
  title = {A three-dimensional human neural cell culture model of Alzheimer's disease.},
  author = {Choi SH, Kim YH, Hebisch M, Sliwinski C, Lee S, D'Avanzo C, Chen H, Hooli B, Asselin C, Muffat J},
  journal = {Nature},
  year = {2014},
  pmid = {25307057},
  doi = {10.1038/nature13800},
  url = {https://pubmed.ncbi.nlm.nih.gov/25307057},
}