% Bibliography for hypothesis h-98b431ba
% Title: TFAM overexpression creates mitochondrial donor-recipient gradients for directed organelle trafficking
% Generated: 2026-06-08T02:39:34Z

@article{pmid41592400,
  title = {In vitro investigation of miR-206-3p-loaded extracellular vesicles as modulators of Aβ-induced neurodegeneration.},
  author = {["G\u00f6n\u00fcll\u00fc S", "Ayd\u0131n \u015e", "\u00c7elik H", "\u00c7elik O", "K\u00fc\u00e7\u00fckler S", "Topal A", "Akay R", "Y\u0131ld\u0131z M", "Al\u0131m B", "\u00c7ulha M"]},
  journal = {Biochemical and biophysical research communications},
  year = {2026},
  pmid = {41592400},
  doi = {10.1016/j.bbrc.2026.153306},
}

@article{pmid41648569,
  title = {Butyrate extends health and lifespan in mice with mitochondrial deficiency.},
  author = {["Gaband\u00e9-Rodr\u00edguez E", "G\u00f3mez de Las Heras M", "Ram\u00edrez-Ruiz de Erenchun P", "Sim\u00f3 C", "Garc\u00eda-Ca\u00f1as V", "Inohara N", "Berenguer-L\u00f3pez I", "Enr\u00edquez-Zarralanga V", "Fern\u00e1ndez-Almeida \u00c1", "Oller J"]},
  journal = {bioRxiv : the preprint server for biology},
  year = {2026},
  pmid = {41648569},
  doi = {10.64898/2026.01.13.699287},
}

@article{pmid41754992,
  title = {miR-137-5p-Loaded Milk-Derived Small Extracellular Vesicles Modulate Oxidative Stress, Mitochondrial Dysfunction, and Neuroinflammatory Responses in an In Vitro Alzheimer's Disease Model.},
  author = {["G\u00f6n\u00fcll\u00fc S", "Ayd\u0131n \u015e", "\u00c7elik H", "\u00c7elik O", "K\u00fc\u00e7\u00fckler S", "Topal A", "Akay R", "Y\u0131ld\u0131z M", "Al\u0131m B", "\u00d6zdemir S"]},
  journal = {Pharmaceutics},
  year = {2026},
  pmid = {41754992},
  doi = {10.3390/pharmaceutics18020251},
}

@article{pmid41826362,
  title = {Butyrate extends health and lifespan in mice with mitochondrial deficiency.},
  author = {["Gaband\u00e9-Rodr\u00edguez E", "G\u00f3mez de Las Heras M", "Ram\u00edrez-Ruiz de Erenchun P", "Sim\u00f3 C", "Garc\u00eda-Ca\u00f1as V", "Inohara N", "Berenguer-L\u00f3pez I", "Enr\u00edquez-Zarralanga V", "Fern\u00e1ndez-Almeida \u00c1", "Oller J"]},
  journal = {Nature communications},
  year = {2026},
  pmid = {41826362},
  doi = {10.1038/s41467-026-70547-4},
}

@article{pmid41842966,
  title = {m6A deficiency induces dopaminergic neurodegeneration and progressive parkinsonism through a pathogenic loop with mitochondria.},
  author = {["Liu S", "Ren Q", "Mo G", "Li Z", "Huang H", "Zhou Y", "Miao Z", "Cao X", "Wu B", "Xiao Z"]},
  journal = {The Journal of clinical investigation},
  year = {2026},
  pmid = {41842966},
  doi = {10.1172/JCI197183},
}

@article{pmid41888517,
  title = {NRIP1 co-activates nuclear translocated FOXO3 to upregulate TFAM expression and promote radioresistance in non-small cell lung cancer.},
  author = {["Zha Y", "Huang H", "Liu Y", "Wan M", "Yao Q", "Chen H", "Xiong J", "Zhong M"]},
  journal = {Cell death discovery},
  year = {2026},
  pmid = {41888517},
  doi = {10.1038/s41420-026-03028-8},
}

@article{pmid41897402,
  title = {Next-Generation Metabolic Reprogramming in iPSC-Derived Cardiomyocytes: CRISPR-EV Synergy for Precision Cardiac Regeneration.},
  author = {["Shahannaz D", "Sugiura T"]},
  journal = {Biomolecules},
  year = {2026},
  pmid = {41897402},
  doi = {10.3390/biom16030467},
}

@article{pmid41897431,
  title = {PM},
  author = {["Somayajulu M", "Wright R", "Muhammed F", "McClellan S", "Ibrahim A", "Hazlett L"]},
  journal = {Antioxidants (Basel, Switzerland)},
  year = {2026},
  pmid = {41897431},
  doi = {10.3390/antiox15030284},
}

@article{pmid41897550,
  title = {Melatonin Ameliorates decaBDE-Induced Autism-Relevant Behaviors Through Promoting SIRT1/SIRT3/FOXO3a-Dependent Mitochondrial Quality Control.},
  author = {["Gao L", "Shen J", "Gao J", "Li T", "Yan D", "Zeng X", "Meng J", "Li H", "Chen D", "Wu J"]},
  journal = {Antioxidants (Basel, Switzerland)},
  year = {2026},
  pmid = {41897550},
  doi = {10.3390/antiox15030405},
}

@article{pmid41898789,
  title = {Vav-iCre-Mediated Deletion of TFAM Is Not Recoverable and Is Consistent with Embryonic Lethality.},
  author = {["Ghosh R", "Shakur E", "Yousefzadeh M"]},
  journal = {Genes},
  year = {2026},
  pmid = {41898789},
  doi = {10.3390/genes17030255},
}

@article{pmid41900149,
  title = {Effect of (-)-Epicatechin on Mitochondrial Homeostasis in Skeletal Muscle of Female Obese Rats.},
  author = {Herrera-Cogco EC, Herrera-Meza S, Martínez-Meza Y, Pérez-Durán J, Ceballos G, Méndez-Bolaina E, Nájera N},
  journal = {Molecules (Basel, Switzerland)},
  year = {2026},
  pmid = {41900149},
  doi = {10.3390/molecules31061050},
  url = {https://pubmed.ncbi.nlm.nih.gov/41900149/},
}

@article{pmid41900996,
  title = {Structural Analysis of Human LonP1 Protease Bound with the Native Substrate.},
  author = {Li M, Liu H, Zhang S, Gao Q, Li S, Wang J, Zhang K},
  journal = {Life (Basel, Switzerland)},
  year = {2026},
  pmid = {41900996},
  doi = {10.3390/life16030478},
  url = {https://pubmed.ncbi.nlm.nih.gov/41900996/},
}

@article{pmid41908442,
  title = {Enhancing the Optical Properties of MAPbI3 Perovskites Passivated with Coordinating and Hydrogen Bond Donor Ligands.},
  author = {Gamarde M, Jouaiti A, Chartrand D, Anthony Raj MR, Skene WG, Ferlay S},
  journal = {ACS omega},
  year = {2026},
  pmid = {41908442},
  doi = {10.1021/acsomega.5c11480},
  url = {https://pubmed.ncbi.nlm.nih.gov/41908442/},
}

@article{pmid41911987,
  title = {Ginseng stem and leaf saponins attenuates pulmonary fibrosis by regulating TFAM-mtDNA homeostasis and suppressing ZBP1-mediated PANoptosis.},
  author = {Chen Y, Hu L, Fu Q, Chen H, Jiang Z, Li X},
  journal = {Journal of ethnopharmacology},
  year = {2026},
  pmid = {41911987},
  doi = {10.1016/j.jep.2026.121597},
  url = {https://pubmed.ncbi.nlm.nih.gov/41911987/},
}

@article{pmid41922875,
  title = {MitoPerturb-Seq identifies gene-specific single-cell responses to mitochondrial DNA depletion and heteroplasmy.},
  author = {Burr SP, Auckland K, Glynos A, Dhawanjewar A, Ryall C, Wei W, Hynes-Allen A, Prater M, Sczaniecka-Clift M, Prudent J, Chinnery PF, van den Ameele J},
  journal = {Nature structural & molecular biology},
  year = {2026},
  pmid = {41922875},
  doi = {10.1038/s41594-026-01779-7},
  url = {https://pubmed.ncbi.nlm.nih.gov/41922875/},
}

@article{pmid40533746,
  title = {Exosomes as nanocarriers for brain-targeted delivery of therapeutic nucleic acids: advances and challenges.},
  author = {["Sanadgol N", "Abedi M", "Hashemzaei M", "Kamran Z", "Khalseh R", "Beyer C", "Voelz C"]},
  journal = {Journal of nanobiotechnology},
  year = {2025},
  pmid = {40533746},
  doi = {10.1186/s12951-025-03528-2},
}

@article{pmid40621827,
  title = {Mitochondrial topoisomerases, nucleoid architecture and mtDNA repair in human disease.},
  author = {Bhattacharjee S, Das BB},
  journal = {Journal of cell science},
  year = {2025},
  pmid = {40621827},
  doi = {10.1242/jcs.263638},
  url = {https://pubmed.ncbi.nlm.nih.gov/40621827/},
}

@article{pmid40779354,
  title = {Dopaminergic Neuron-Specific Tfam Knockout Links Inter-Organelle Miscommunication to Early-Onset Parkinsonism.},
  author = {Shen W, Zheng M, Zhao Y, Ni F, Zhu X},
  journal = {FASEB journal : official publication of the Federation of American Societies for Experimental Biology},
  year = {2025},
  pmid = {40779354},
  doi = {10.1096/fj.202501454RR},
  url = {https://pubmed.ncbi.nlm.nih.gov/40779354/},
}

@article{pmid41454214,
  title = {Deciphering the PGC-1α-TFAM Axis in Parkinson's Disease (PD) - A Mechanism Approach Targeting Therapeutics for PD.},
  author = {Iyer M, Kinoshita M, Reddy DH, Babu HWS, Lakhanpal V, Yadav MK, Krishnan J, Palanivel V, Faris S, Chauhan K, Vellingiri B},
  journal = {Molecular neurobiology},
  year = {2025},
  pmid = {41454214},
  doi = {10.1007/s12035-025-05611-z},
  url = {https://pubmed.ncbi.nlm.nih.gov/41454214/},
}

@article{pmid37651673,
  title = {Melatonin attenuates sepsis-induced acute kidney injury by promoting mitophagy through SIRT3-mediated TFAM deacetylation.},
  author = {Deng Z, He M, Hu H, Zhang W, Zhang Y, Ge Y, Ma T, Wu J, Li L, Sun M},
  journal = {Autophagy},
  year = {2024},
  pmid = {37651673},
  doi = {10.1080/15548627.2023.2252265},
  url = {https://pubmed.ncbi.nlm.nih.gov/37651673},
}

@article{pmid38783142,
  title = {TFAM is an autophagy receptor that limits inflammation by binding to cytoplasmic mitochondrial DNA.},
  author = {Liu H, Zhen C, Xie J, Luo Z, Zeng L, Zhao G, Lu S, Zhuang H, Fan H, Li X},
  journal = {Nat Cell Biol},
  year = {2024},
  pmid = {38783142},
  doi = {10.1038/s41556-024-01419-6},
  url = {https://pubmed.ncbi.nlm.nih.gov/38783142},
}

@article{pmid39379554,
  title = {DELE1 maintains muscle proteostasis to promote growth and survival in mitochondrial myopathy.},
  author = {Lin HP, Petersen JD, Gilsrud AJ, Madruga A, D'Silva TM, Huang X, Shammas MK, Randolph NP, Johnson KR, Li Y, Jones DR, Pacold ME, Narendra DP},
  journal = {The EMBO journal},
  year = {2024},
  pmid = {39379554},
  doi = {10.1038/s44318-024-00242-x},
  url = {https://pubmed.ncbi.nlm.nih.gov/39379554/},
}

@article{pmid35233090,
  title = {Mitochondrial-derived damage-associated molecular patterns amplify neuroinflammation in neurodegenerative diseases.},
  author = {Lin MM, Liu N, Qin ZH, Wang Y},
  journal = {Acta Pharmacol Sin},
  year = {2022},
  pmid = {35233090},
  doi = {10.1038/s41401-022-00879-6},
  url = {https://pubmed.ncbi.nlm.nih.gov/35233090},
}

@article{pmid32186434,
  title = {Mitochondrial DNA stress triggers autophagy-dependent ferroptotic death.},
  author = {Li C, Zhang Y, Liu J, Kang R, Klionsky DJ, Tang D},
  journal = {Autophagy},
  year = {2021},
  pmid = {32186434},
  doi = {10.1080/15548627.2020.1739447},
  url = {https://pubmed.ncbi.nlm.nih.gov/32186434},
}

@article{pmid33314045,
  title = {Mitochondrial DNA copy number in human disease: the more the better?},
  author = {Filograna R, Mennuni M, Alsina D, Larsson NG},
  journal = {FEBS Lett},
  year = {2021},
  pmid = {33314045},
  doi = {10.1002/1873-3468.14021},
  url = {https://pubmed.ncbi.nlm.nih.gov/33314045},
}

@article{pmid33369392,
  title = {Mesenchymal Stem Cell-Derived Extracellular Vesicles Attenuate Mitochondrial Damage and Inflammation by Stabilizing Mitochondrial DNA.},
  author = {Zhao M, Liu S, Wang C, Wang Y, Wan M, Liu F, Gong M, Yuan Y, Chen Y, Cheng J, Lu Y, Liu J},
  journal = {ACS nano},
  year = {2021},
  pmid = {33369392},
  doi = {10.1021/acsnano.0c08947},
  url = {https://pubmed.ncbi.nlm.nih.gov/33369392/},
}

@article{pmid33408785,
  title = {Mitochondrial ROS promote mitochondrial dysfunction and inflammation in ischemic acute kidney injury by disrupting TFAM-mediated mtDNA maintenance.},
  author = {Zhao M, Wang Y, Li L, Liu S, Wang C, Yuan Y, Yang G, Chen Y, Cheng J, Lu Y},
  journal = {Theranostics},
  year = {2021},
  pmid = {33408785},
  doi = {10.7150/thno.50905},
  url = {https://pubmed.ncbi.nlm.nih.gov/33408785},
}

@article{pmid32183942,
  title = {N6-Deoxyadenosine Methylation in Mammalian Mitochondrial DNA.},
  author = {Hao Z, Wu T, Cui X, Zhu P, Tan C, Dou X, Hsu KW, Lin YT, Peng PH, Zhang LS, Gao Y, Hu L, Sun HL, Zhu A, Liu J, Wu KJ, He C},
  journal = {Molecular cell},
  year = {2020},
  pmid = {32183942},
  doi = {10.1016/j.molcel.2020.02.018},
  url = {https://pubmed.ncbi.nlm.nih.gov/32183942/},
}

@article{pmid28301064,
  title = {Mitochondrial biogenesis in neurodegeneration.},
  author = {Li PA, Hou X, Hao S},
  journal = {Journal of neuroscience research},
  year = {2017},
  pmid = {28301064},
  doi = {10.1002/jnr.24042},
  url = {https://pubmed.ncbi.nlm.nih.gov/28301064/},
}