% Bibliography for hypothesis h-a1b56d74
% Title: Metabolic Switch Targeting for A1→A2 Repolarization
% Generated: 2026-06-08T02:41:06Z

@article{pmid40582563,
  title = {Aryl hydrocarbon receptor impairs HK2-controlled flux of the hexosamine biosynthesis pathway to suppress NETosis in an N-glycosylation-dependent manner.},
  author = {Li S, Zhu J, Song J, Yang L, Gong Y et al.},
  journal = {J Adv Res},
  year = {2026},
  pmid = {40582563},
  doi = {doi: 10.1016/j.jare.2025.06.078},
  url = {https://pubmed.ncbi.nlm.nih.gov/40582563/},
}

@article{pmid41023273,
  title = {HDAC3 mediates retinal endothelial cell metabolic reprogramming and angiogenesis.},
  author = {Mitchell CD, Morris CA, Wild M, Cunningham A, Chuesiang P et al.},
  journal = {Acta Pharmacol Sin},
  year = {2026},
  pmid = {41023273},
  doi = {doi: 10.1038/s41401-025-01642-3},
  url = {https://pubmed.ncbi.nlm.nih.gov/41023273/},
}

@article{pmid41229334,
  title = {Hypoxia-Induced Histone Lactylation Promotes Ferroptosis in Cardiomyocytes via the Wnt/β-Catenin Pathway.},
  author = {Zhu XH, Hou JW, Lv ZY, Sun MH, Zhang XY et al.},
  journal = {Kaohsiung J Med Sci},
  year = {2026},
  pmid = {41229334},
  doi = {doi: 10.1002/kjm2.70123},
  url = {https://pubmed.ncbi.nlm.nih.gov/41229334/},
}

@article{pmid41387352,
  title = {HK1 and HK2 Beyond Glycolysis: Mitochondrial Interactions and Dual Roles in Metabolism and Cell Fate.},
  author = {Pesce NA, Seminara G, Giarrusso G, Tomasello MF},
  journal = {Adv Biol (Weinh)},
  year = {2026},
  pmid = {41387352},
  doi = {10.1002/adbi.202500472},
  url = {https://pubmed.ncbi.nlm.nih.gov/41387352},
}

@article{pmid41447776,
  title = {Granzyme B knockdown inhibits NLRP3-mediated pyroptosis and the JAK2/STAT3 signaling in renal fibrosis.},
  author = {Wang M, Chen D, Zhang D, Han H, Xie M et al.},
  journal = {Tissue Cell},
  year = {2026},
  pmid = {41447776},
  doi = {doi: 10.1016/j.tice.2025.103216},
  url = {https://pubmed.ncbi.nlm.nih.gov/41447776/},
}

@article{pmid41548699,
  title = {Targeting glycolysis in prostate cancer: Molecular mechanisms and therapeutic advances.},
  author = {Zhang J, Zhang T, Song D, Xu D},
  journal = {Biochim Biophys Acta Rev Cancer},
  year = {2026},
  pmid = {41548699},
  doi = {doi: 10.1016/j.bbcan.2026.189537},
  url = {https://pubmed.ncbi.nlm.nih.gov/41548699/},
}

@article{pmid41897347,
  title = {Investigating the Effect and Mechanism of Protocatechuic Aldehyde on Vascular Dementia Based on Multi-Omics Approach.},
  author = {["Xiao T", "Tao J", "Tan J", "Yi X", "Wang Z", "Duan X"]},
  journal = {Biomolecules},
  year = {2026},
  pmid = {41897347},
  doi = {10.3390/biom16030411},
}

@article{pmid41901183,
  title = {From Phytochemical Characterization to Energy Metabolism-Driven Molecular Responses: The Anticancer Potential of Lactarius deliciosus (L.) Gray in Breast Cancer Cells.},
  author = {Gülüm L, Güler E, Çapkınoğlu E, Çelik AB, Tutar Y},
  journal = {Nutrients},
  year = {2026},
  pmid = {41901183},
  doi = {10.3390/nu18061008},
  url = {https://pubmed.ncbi.nlm.nih.gov/41901183/},
}

@article{pmid41901335,
  title = {A Novel Dual URAT1/GLUT9 Inhibitor Reduces Hyperuricemia by Enhancing Uric Acid Excretion and Attenuating Renal Fibrosis.},
  author = {Zhang H, Huang J, Yang W, Zhou W, Ding J, Li Q, Hu G},
  journal = {Pharmaceuticals (Basel, Switzerland)},
  year = {2026},
  pmid = {41901335},
  doi = {10.3390/ph19030490},
  url = {https://pubmed.ncbi.nlm.nih.gov/41901335/},
}

@article{pmid41902192,
  title = {STING Degradation by PRRSV Activates HK2-Mediated Glycolysis to Facilitate Viral Replication.},
  author = {Luo L, Zhou L, Gao X, Li Y, Zhou H, Li Y, Zhang Z},
  journal = {Viruses},
  year = {2026},
  pmid = {41902192},
  doi = {10.3390/v18030284},
  url = {https://pubmed.ncbi.nlm.nih.gov/41902192/},
}

@article{pmid41905095,
  title = {Duzhong-Gegen formula ameliorated hyperuricemia by enhancing renal uric acid excretion through activation of SIRT1.},
  author = {Wang L, Gan Y, Huang J, Long L, Li S, Wang X, Xie T, Zhu Q},
  journal = {Phytomedicine : international journal of phytotherapy and phytopharmacology},
  year = {2026},
  pmid = {41905095},
  doi = {10.1016/j.phymed.2026.158091},
  url = {https://pubmed.ncbi.nlm.nih.gov/41905095/},
}

@article{pmid41921767,
  title = {Erchen decoction and its active flavonoids hesperidin and quercetin alleviate high-fat diet-induced neuroinflammation by targeting HK2-mediated microglial glycolysis.},
  author = {Zheng M, Yang K, Ma Y, Suo W, Li J, Huang Y, Gao P, Liu K, Zhang Y, Liu H, Guan L, Yan F, Xu J, Liu T, Xu J},
  journal = {Journal of ethnopharmacology},
  year = {2026},
  pmid = {41921767},
  doi = {10.1016/j.jep.2026.121603},
  url = {https://pubmed.ncbi.nlm.nih.gov/41921767/},
}

@article{pmid39987285,
  title = {Glucose Metabolic Reprogramming in Microglia: Implications for Neurodegenerative Diseases and Targeted Therapy.},
  author = {Fang M, Zhou Y, He K, Lu Y, Tao F, Huang H},
  journal = {Mol Neurobiol},
  year = {2025},
  pmid = {39987285},
  doi = {10.1007/s12035-025-04775-y},
  url = {https://pubmed.ncbi.nlm.nih.gov/39987285},
}

@article{pmid40014451,
  title = {Hexokinase 2-mediated metabolic stress and inflammation burden of liver macrophages via histone lactylation in MASLD.},
  author = {Li J, Chen X, Song S, Jiang W, Geng T, Wang T, Xu Y, Zhu Y, Lu J, Xia Y},
  journal = {Cell Rep},
  year = {2025},
  pmid = {40014451},
  doi = {10.1016/j.celrep.2025.115350},
  url = {https://pubmed.ncbi.nlm.nih.gov/40014451},
}

@article{pmid40531619,
  title = {Hexokinase 2 interacts with PINK1 to facilitate mitophagy in astrocytes and restrain inflammation-induced neurotoxicity.},
  author = {["Howden J", "Hakansson H", "Nieto-Rostro M", "McAdam R", "Arber C", "Brandon N", "Kittler J"]},
  journal = {Cell reports},
  year = {2025},
  pmid = {40531619},
  doi = {10.1016/j.celrep.2025.115809},
}

@article{pmid38904014,
  title = {The PI3K/Akt Pathway and Glucose Metabolism: A Dangerous Liaison in Cancer.},
  author = {Fontana F, Giannitti G, Marchesi S, Limonta P},
  journal = {Int J Biol Sci},
  year = {2024},
  pmid = {38904014},
  doi = {10.7150/ijbs.89942},
  url = {https://pubmed.ncbi.nlm.nih.gov/38904014},
}

@article{pmid36997025,
  title = {Protective Effect of alpha-Tocopherol Against Ochratoxin A in Kidney Cell Line HK-2.},
  author = {["Lee H", "Kim H", "Ryu D"]},
  journal = {Journal of food protection},
  year = {2023},
  pmid = {36997025},
  doi = {10.1016/j.jfp.2023.100082},
}

@article{pmid33946854,
  title = {Hexokinase 2 in Cancer: A Prima Donna Playing Multiple Characters.},
  author = {Ciscato F, Ferrone L, Masgras I, Laquatra C, Rasola A},
  journal = {International journal of molecular sciences},
  year = {2021},
  pmid = {33946854},
  doi = {10.3390/ijms22094716},
  url = {https://pubmed.ncbi.nlm.nih.gov/33946854/},
}

@article{pmid31929272,
  title = {The impact of gender matching between donor and recipient on the outcome of kidney transplant patients: A retrospective study.},
  author = {["Abou-Jaoude M", "El-Helou E", "Nasser H", "Kansoun A"]},
  journal = {Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia},
  year = {2019},
  pmid = {31929272},
  doi = {10.4103/1319-2442.275469},
}

@article{pmid26975021,
  title = {Metabolic phenotype of bladder cancer.},
  author = {Massari F, Ciccarese C, Santoni M, Iacovelli R, Mazzucchelli R, Piva F, Scarpelli M, Berardi R, Tortora G, Lopez-Beltran A},
  journal = {Cancer Treat Rev},
  year = {2016},
  pmid = {26975021},
  doi = {10.1016/j.ctrv.2016.03.005},
  url = {https://pubmed.ncbi.nlm.nih.gov/26975021},
}

@article{pmid25452455,
  title = {Hereditary colorectal cancer syndromes: American Society of Clinical Oncology Clinical Practice Guideline endorsement of the familial risk-colorectal cancer: European Society for Medical Oncology Clinical Practice Guidelines.},
  author = {["Stoffel E", "Mangu P", "Gruber S", "Hamilton S", "Kalady M", "Lau M", "Lu K", "Roach N", "Limburg P"]},
  journal = {Journal of clinical oncology : official journal of the American Society of Clinical Oncology},
  year = {2015},
  pmid = {25452455},
  doi = {10.1200/JCO.2014.58.1322},
}

@article{pmid26075878,
  title = {HK2/hexokinase-II integrates glycolysis and autophagy to confer cellular protection.},
  author = {Tan VP, Miyamoto S},
  journal = {Autophagy},
  year = {2015},
  pmid = {26075878},
  doi = {10.1080/15548627.2015.1042195},
  url = {https://pubmed.ncbi.nlm.nih.gov/26075878/},
}