% Bibliography for hypothesis h-af0ec8d843 % Title: Complement C1q-Mediated Synaptic Pruning Drives Early Cognitive Decline in Alzheimer's Disease % Generated: 2026-04-28T05:51:56Z @article{pmid41396874, title = {Pioglitazone attenuates complement-mediated microglial synaptic engulfment in an Alzheimer's disease model.}, journal = {Brain : a journal of neurology}, year = {2026}, pmid = {41396874}, doi = {10.1093/brain/awaf462}, } @article{pmid41000995, title = {Young adult microglial deletion of C1q reduces engulfment of synapses and prevents cognitive impairment in an aggressive Alzheimer's disease mouse model.}, author = {Petrisko TJ, Chu SH, Gomez-Arboledas A, Zhang B, Tenner AJ}, journal = {bioRxiv : the preprint server for biology}, year = {2025}, pmid = {41000995}, doi = {10.1101/2025.09.13.676049}, url = {https://pubmed.ncbi.nlm.nih.gov/41000995/}, } @article{pmid38278523, title = {C5aR1 signaling promotes region- and age-dependent synaptic pruning in models of Alzheimer's disease.}, author = {["Angela Gomez-Arboledas", "Maria I Fonseca", "Enik\u00f6 Kramar", "Shu-Hui Chu", "Nicole D Schartz", "Purnika Selvan", "Marcelo A Wood", "Andrea J Tenner"]}, journal = {Alzheimer's & dementia : the journal of the Alzheimer's Association}, year = {2024}, pmid = {38278523}, doi = {10.1002/alz.13682}, } @article{pmid34595138, title = {The Role of Complement in Synaptic Pruning and Neurodegeneration.}, author = {Gomez-Arboledas A, Acharya MM, Tenner AJ}, journal = {ImmunoTargets and therapy}, year = {2021}, pmid = {34595138}, doi = {10.2147/ITT.S305420}, url = {https://pubmed.ncbi.nlm.nih.gov/34595138/}, }