% Bibliography for hypothesis h-cross-synth-grn-lysosomal-microglia % Title: GRN/progranulin lysosomal insufficiency across FTD, ALS-spectrum stress, and AD inflammation % Generated: 2026-06-13T22:38:19Z @article{pmid28930663, title = {The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases.}, author = {Krasemann S, Madore C, Cialic R, Baufeld C, Calcagno N, El Fatimy R, Beckers L, O'Loughlin E, Xu Y, Fanek Z}, journal = {Immunity}, year = {2017}, pmid = {28930663}, doi = {10.1016/j.immuni.2017.08.008}, url = {https://pubmed.ncbi.nlm.nih.gov/28930663}, } @article{pmid16862115, title = {Null mutations in progranulin cause ubiquitin-positive frontotemporal dementia linked to chromosome 17q21.}, journal = {Nature}, year = {2006}, pmid = {16862115}, doi = {10.1038/nature05017}, } @article{pmid16862116, title = {Mutations in progranulin cause tau-negative frontotemporal dementia linked to chromosome 17.}, journal = {Nature}, year = {2006}, pmid = {16862116}, doi = {10.1038/nature05016}, }