% Bibliography for hypothesis h-db6aa4b1 % Title: Mechanosensitive Ion Channel Reprogramming % Generated: 2026-06-08T16:04:00Z @article{pmid40653265, title = {Direct pharmacological targeting of Piezo1 by Paeoniflorin: a novel therapeutic approach for renal fibrosis.}, author = {["Li R", "Xia J", "Shi C", "Zhang K", "Qu Y", "He G", "Fu Z", "Deng L", "Liu R", "Wang X"]}, journal = {Journal of advanced research}, year = {2026}, pmid = {40653265}, doi = {10.1016/j.jare.2025.07.015}, } @article{pmid41437911, title = {Piezo-type mechanosensitive ion channel component 1: a mechano-bioenergetic transducer in the tumour microenvironment.}, author = {["Zhang Y", "Gao C", "Li Y", "Fu Q", "Liu Y", "Mo N", "Yue J", "Wang Y"]}, journal = {Annals of medicine}, year = {2026}, pmid = {41437911}, doi = {10.1080/07853890.2025.2603022}, } @article{pmid39722451, title = {Amyloid beta Aβ}, author = {["Lim X", "Willemse L", "Harraz O"]}, journal = {Biophysical journal}, year = {2025}, pmid = {39722451}, doi = {10.1016/j.bpj.2024.12.025}, } @article{pmid39824919, title = {Mechanosensation of the heart and gut elicits hypometabolism and vigilance in mice.}, author = {["Scott K", "Tan Y", "Johnson D", "Elsaafien K", "Baumer-Harrison C", "M\u00e9ndez-Hern\u00e1ndez R", "Kirchner M", "Eikenberry S", "Sa J", "Stern J"]}, journal = {Nature metabolism}, year = {2025}, pmid = {39824919}, doi = {10.1038/s42255-024-01205-6}, } @article{pmid40009679, title = {Local soft niches in mechanically heterogeneous primary tumors promote brain metastasis via mechanotransduction-mediated HDAC3 activity.}, author = {["Tang K", "Zheng Y", "Hu G", "Xin Y", "Li K", "Zhang C", "Chen X", "Zhang B", "Li X", "Hu B"]}, journal = {Science advances}, year = {2025}, pmid = {40009679}, doi = {10.1126/sciadv.adq2881}, } @article{pmid40194731, title = {Emerging roles of mechanically activated ion channels in autoimmune disease.}, author = {["Zeng Z", "Chen E", "Xue J"]}, journal = {Autoimmunity reviews}, year = {2025}, pmid = {40194731}, doi = {10.1016/j.autrev.2025.103813}, } @article{pmid40750459, title = {Piezo1: structural pharmacology and mechanotransduction mechanisms.}, author = {["Wang J", "Jing F", "Zhao Y", "You Z", "Zhang A", "Qin S"]}, journal = {Trends in pharmacological sciences}, year = {2025}, pmid = {40750459}, doi = {10.1016/j.tips.2025.06.009}, } @article{pmid40894745, title = {Corticosteroids elevate intraocular pressure through suppression of TREK-1 signaling.}, author = {Redmon SN, Yarishkin O, Rudzitis CN, Lakk M, Bertrand J, van Batenburg-Sherwood J, Nicou CM, Passaglia CL, Overby DR, Križaj D}, journal = {bioRxiv : the preprint server for biology}, year = {2025}, pmid = {40894745}, doi = {10.1101/2025.08.14.670390}, url = {https://pubmed.ncbi.nlm.nih.gov/40894745/}, } @article{pmid40950697, title = {Identification of mechanosensitive ion channel-related molecular subtypes and key genes for ovarian cancer.}, author = {Zhang L, Wang L, Wang M, Peng K, Chen H, Wang X, Zhou L}, journal = {Transl Cancer Res}, year = {2025}, pmid = {40950697}, doi = {10.21037/tcr-2025-1219}, url = {https://pubmed.ncbi.nlm.nih.gov/40950697}, } @article{pmid41051683, title = {PIEZO1: a mechanosensitive ion channel in the pathogenesis and pharmacotherapy of diabetic neuropathy.}, author = {Gupta T, Singh TG, Singh R}, journal = {Molecular biology reports}, year = {2025}, pmid = {41051683}, doi = {10.1007/s11033-025-11114-w}, url = {https://pubmed.ncbi.nlm.nih.gov/41051683/}, } @article{pmid41195420, title = {Mechanosensitive channel Piezo1 in calcium dynamics: structure, function, and emerging therapeutic strategies.}, author = {Liu Y, Xu YQ, Long YY, Xiao H, Ma YY, Li YW}, journal = {Frontiers in molecular biosciences}, year = {2025}, pmid = {41195420}, doi = {10.3389/fmolb.2025.1693456}, url = {https://pubmed.ncbi.nlm.nih.gov/41195420/}, } @article{pmid41268978, title = {Mechano- and Glucocorticoid-Sensitive TREK-1 Channels Regulate Conventional Outflow and Intraocular Pressure.}, author = {Redmon SN, Yarishkin O, Rudzitis CN, Lakk M, Bertrand J, van Batenburg-Sherwood J, Nicou CM, Passaglia CL, Overby DR, Križaj D}, journal = {Invest Ophthalmol Vis Sci}, year = {2025}, pmid = {41268978}, doi = {10.1167/iovs.66.14.57}, url = {https://pubmed.ncbi.nlm.nih.gov/41268978}, } @article{pmid39375369, title = {Endothelial Piezo1 channel mediates mechano-feedback control of brain blood flow.}, author = {["Lim X", "Abd-Alhaseeb M", "Ippolito M", "Koide M", "Senatore A", "Plante C", "Hariharan A", "Weir N", "Longden T", "Laprade K"]}, journal = {Nature communications}, year = {2024}, pmid = {39375369}, doi = {10.1038/s41467-024-52969-0}, } @article{pmid39436995, title = {Mechanosensing by Piezo1 in gastric ghrelin cells contributes to hepatic lipid homeostasis in mice.}, author = {["Zhang J", "Zhao Y", "Wu S", "Han M", "Gao L", "Yang K", "Chen H", "Wang C", "Xu G"]}, journal = {Science signaling}, year = {2024}, pmid = {39436995}, doi = {10.1126/scisignal.adq9463}, } @article{pmid39789885, title = {Inflammation alters the expression and activity of the mechanosensitive ion channels in periodontal ligament cells.}, author = {Ren J, Zhan C, Lin Y}, journal = {Eur J Orthod}, year = {2024}, pmid = {39789885}, doi = {10.1093/ejo/cjae079}, url = {https://pubmed.ncbi.nlm.nih.gov/39789885}, } @article{pmid36526145, title = {Mechanosensitive ion channel Piezo1 mediates mechanical ventilation-exacerbated ARDS-associated pulmonary fibrosis.}, author = {["Fang X", "Li M", "Wang Y", "Zhang P", "Sun M", "Xu J", "Yang Y", "He Y", "Yu Y", "Li R"]}, journal = {Journal of advanced research}, year = {2023}, pmid = {36526145}, doi = {10.1016/j.jare.2022.12.006}, } @article{pmid37172572, title = {Biophysical and mechanobiological considerations for T-cell-based immunotherapy.}, author = {["Zhuang C", "Gould J", "Enninful A", "Shao S", "Mak M"]}, journal = {Trends in pharmacological sciences}, year = {2023}, pmid = {37172572}, doi = {10.1016/j.tips.2023.03.007}, } @article{pmid37532007, title = {Mechanosensitive Piezo1 channel in physiology and pathophysiology of the central nervous system.}, author = {Zong B, Yu F, Zhang X, Pang Y, Zhao W, Sun P, Li L}, journal = {Ageing Res Rev}, year = {2023}, pmid = {37532007}, doi = {10.1016/j.arr.2023.102026}, url = {https://pubmed.ncbi.nlm.nih.gov/37532007}, } @article{pmid37587100, title = {Astroglial Hmgb1 regulates postnatal astrocyte morphogenesis and cerebrovascular maturation.}, author = {["Freitas-Andrade M", "Comin C", "Van Dyken P", "Ouellette J", "Raman-Nair J", "Blakeley N", "Liu Q", "Leclerc S", "Pan Y", "Liu Z"]}, journal = {Nature communications}, year = {2023}, pmid = {37587100}, doi = {10.1038/s41467-023-40682-3}, } @article{pmid35078979, title = {Focused ultrasound excites cortical neurons via mechanosensitive calcium accumulation and ion channel amplification.}, author = {["Yoo S", "Mittelstein D", "Hurt R", "Lacroix J", "Shapiro M"]}, journal = {Nature communications}, year = {2022}, pmid = {35078979}, doi = {10.1038/s41467-022-28040-1}, } @article{pmid31596529, title = {Inhibition of Piezo1 attenuates demyelination in the central nervous system.}, author = {["Velasco-Estevez M", "Gadalla K", "Li\u00f1an-Barba N", "Cobb S", "Dev K", "Sheridan G"]}, journal = {Glia}, year = {2020}, pmid = {31596529}, doi = {10.1002/glia.23722}, } @article{pmid24129537, title = {[Neuromyelitis optica].}, author = {["Kvistad S", "Wergeland S", "Torkildsen \u00d8", "Myhr K", "Vedeler C"]}, journal = {Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke}, year = {2013}, pmid = {24129537}, doi = {10.4045/tidsskr.13.0608}, } @article{pmid14965242, title = {5-HT3 receptors.}, author = {["Costall B", "Naylor R"]}, journal = {Current drug targets. 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