% Bibliography for hypothesis h-gap-456a357b-m3 % Title: protective chromatin remodeling defines the therapeutic window for: Are DNA methylation changes in neurodegeneration causal drivers or protective cons % Generated: 2026-06-15T15:03:09Z @article{pmid31204559, title = {WDR45 contributes to neurodegeneration through regulation of ER homeostasis and neuronal death.}, author = {["Wan Huida", "Wang Qi", "Chen Xiuting", "Zeng Qiufang", "Shao Yanjiao"]}, journal = {Autophagy}, year = {2020}, pmid = {31204559}, doi = {10.1212/NXG.0000000000000124}, } @article{pmid31204559, title = {WDR45 contributes to neurodegeneration through regulation of ER homeostasis and neuronal death.}, author = {["Wan Huida", "Wang Qi", "Chen Xiuting", "Zeng Qiufang", "Shao Yanjiao"]}, journal = {Autophagy}, year = {2020}, pmid = {31204559}, } @article{pmid33031745, title = {TDP-43 Triggers Mitochondrial DNA Release via mPTP to Activate cGAS/STING in ALS.}, author = {Yu CH, Davidson S, Harapas CR, Hilton JB, Mlodzianoski MJ, Laohamonthonkul P, Louis C, Low RRJ, Moecking J, De Nardo D}, journal = {Cell}, year = {2020}, pmid = {33031745}, doi = {10.1016/j.cell.2020.09.020}, url = {https://pubmed.ncbi.nlm.nih.gov/33031745}, } @article{pmid33031745, title = {TDP-43 Triggers Mitochondrial DNA Release via mPTP to Activate cGAS/STING in ALS.}, author = {Yu CH, Davidson S, Harapas CR, Hilton JB, Mlodzianoski MJ, Laohamonthonkul P, Louis C, Low RRJ, Moecking J, De Nardo D}, journal = {Cell}, year = {2020}, pmid = {33031745}, } @article{pmid30643298, title = {Premature polyadenylation-mediated loss of stathmin-2 is a hallmark of TDP-43-dependent neurodegeneration.}, author = {Melamed Ze'ev; López-Erauskin Jone; Baughn Michael W; Zhang Ouyang; Drenner Kevin; Sun Ying; Freyermuth Fernande; McMahon Moira A; Beccari Melinda S; Artates Jon W; Ohkubo Takuya; Rodriguez Maria; Lin Nianwei; Wu Dongmei; Bennett C Frank; Rigo Frank; Da Cruz Sandrine; Ravits John; Lagier-Tourenne Clotilde; Cleveland Don W}, journal = {Nature neuroscience}, year = {2019}, pmid = {30643298}, doi = {10.1038/s41593-018-0293-z}, } @article{pmid30643298, title = {Premature polyadenylation-mediated loss of stathmin-2 is a hallmark of TDP-43-dependent neurodegeneration.}, author = {Melamed Z, López-Erauskin J, Baughn MW, Zhang O, Drenner K, Sun Y, Freyermuth F, McMahon MA, Beccari MS, Artates JW, Ohkubo T, Rodriguez M, Lin N, Wu D, Bennett CF, Rigo F, Da Cruz S, Ravits J, Lagier-Tourenne C, Cleveland DW}, journal = {Nature neuroscience}, year = {2019}, pmid = {30643298}, doi = {10.1038/s41593-018-0293-z}, url = {https://pubmed.ncbi.nlm.nih.gov/30643298/}, } @article{pmid27313899, title = {DNA Damage, Neurodegeneration, and Synaptic Plasticity.}, author = {Merlo, Cuchillo-Ibañez, Parlato, Rammes}, journal = {Neural plasticity}, year = {2018}, pmid = {27313899}, } @article{pmid27313899, title = {DNA Damage, Neurodegeneration, and Synaptic Plasticity.}, journal = {Neural Plast}, year = {2016}, pmid = {27313899}, } @article{pmid26424568, title = {Human endogenous retrovirus-K contributes to motor neuron disease.}, author = {Li W, Lee MH, Henderson L, Tyagi R, Bachani M, Steiner J, Campanac E, Hoffman DA, von Geldern G, Johnson K, Maric D, Morris HD, Lentz M, Pak K, Mammen A, Ostrow L, Rothstein J, Nath A}, journal = {Science translational medicine}, year = {2015}, pmid = {26424568}, doi = {10.1126/scitranslmed.aac8201}, url = {https://pubmed.ncbi.nlm.nih.gov/26424568/}, } @article{pmid26424568, title = {Human endogenous retrovirus-K contributes to motor neuron disease.}, author = {Li W, Lee MH, Henderson L, Tyagi R, Bachani M, Steiner J, Campanac E, Hoffman DA, von Geldern G, Johnson K, Maric D, Morris HD, Lentz M, Pak K, Mammen A, Ostrow L, Rothstein J, Nath A}, journal = {Science translational medicine}, year = {2015}, pmid = {26424568}, }