% Bibliography for hypothesis h-trem2-f48baa0c
% Title: TREM2-APOE4 Co-targeting — Simultaneous Correction of Lipid Sensing and Clearance Deficits
% Generated: 2026-06-08T18:07:17Z

@article{pmid41408986,
  title = {Immuno-Regulation of Brain Region-Specific Organoids Containing Isogenic Microglia-Like Cells.},
  author = {Liu C, Ene J, Lu W, Syed F, Sun L, Raulin AC, Ren Y, Wang X, Kanekiyo T, Li Y},
  journal = {Advanced healthcare materials},
  year = {2026},
  pmid = {41408986},
  doi = {10.1002/adhm.202503579},
  url = {https://pubmed.ncbi.nlm.nih.gov/41408986/},
}

@article{pmid41490158,
  title = {Microglial transcriptional profiles of a transgenic rat model closely model Alzheimer's disease.},
  author = {Finno CJ, Ghosh S, Rodriguez V, Valenzuela A, Andrew P et al.},
  journal = {J Alzheimers Dis},
  year = {2026},
  pmid = {41490158},
  doi = {doi: 10.1177/13872877251410206},
  url = {https://pubmed.ncbi.nlm.nih.gov/41490158/},
}

@article{pmid41508098,
  title = {Interpretable machine-learning prediction of PSEN1 missense variant pathogenicity based on multi-omics enrichment in six core Alzheimer's disease genes.},
  author = {Yang D, Wang S, Lu Y, Zhu J, Chen J et al.},
  journal = {Alzheimers Res Ther},
  year = {2026},
  pmid = {41508098},
  doi = {doi: 10.1186/s13195-025-01950-0},
  url = {https://pubmed.ncbi.nlm.nih.gov/41508098/},
}

@article{pmid41569436,
  title = {The Immuno-Glial Connectome in Alzheimer's Disease: Integrating Central and Peripheral Inflammatory Networks.},
  author = {Gopalakrishna PK, Che Mohd Nassir CMN, Anandan S, Hussan F, Dandala KCR, Sura S, Jagadeesan S, Mohd Moklas MA, Vishnumukkala T, Hein ZM},
  journal = {Cellular and molecular neurobiology},
  year = {2026},
  pmid = {41569436},
  doi = {10.1007/s10571-026-01671-4},
  url = {https://pubmed.ncbi.nlm.nih.gov/41569436/},
}

@article{pmid41701875,
  title = {Dysregulated Lipid Metabolism and Neurovascular Unit Dysfunction: Novel Mechanisms Linking Alzheimer's Disease and Vascular Dementia.},
  author = {Li M, Wang H, Tang Z, Yang S, Lin L},
  journal = {Aging Dis},
  year = {2026},
  pmid = {41701875},
  doi = {doi: 10.14336/AD.2025.1464},
  url = {https://pubmed.ncbi.nlm.nih.gov/41701875/},
}

@article{pmid41789102,
  title = {TREM2 and microglial immunity in Alzheimer's disease: mechanisms, genetics, and therapeutic opportunities.},
  author = {Wang T, Liu X, Wang X, Hua F, Yan L},
  journal = {Front Immunol},
  year = {2026},
  pmid = {41789102},
  doi = {doi: 10.3389/fimmu.2026.1739875},
  url = {https://pubmed.ncbi.nlm.nih.gov/41789102/},
}

@article{pmid41907842,
  title = {Molecular mechanism of Alzheimer's disease using integrated multi-omics.},
  author = {Alhusaini M, Mussa BM, Ilce BY, Alhaj H, Hamoudi R},
  journal = {Frontiers in aging neuroscience},
  year = {2026},
  pmid = {41907842},
  doi = {10.3389/fnagi.2026.1735696},
  url = {https://pubmed.ncbi.nlm.nih.gov/41907842/},
}