% Bibliography for hypothesis h-var-be69d8af79 % Title: TBK1 Loss Drives Microglial Senescence-SASP to Generate MMP-9-Mediated TDP-43 C-Terminal Fragments in ALS % Generated: 2026-04-28T19:34:10Z @article{pmid34057020, title = {Autophagy and ALS: mechanistic insights and therapeutic implications.}, author = {Chua JP, De Calbiac H, Kabashi E, Barmada SJ}, journal = {Autophagy}, year = {2022}, pmid = {34057020}, doi = {10.1080/15548627.2021.1926656}, url = {https://pubmed.ncbi.nlm.nih.gov/34057020}, } @article{pmid36201573, title = {Two FTD-ALS genes converge on the endosomal pathway to induce TDP-43 pathology and degeneration.}, journal = {Science}, year = {2022}, pmid = {36201573}, } @article{pmid30458231, title = {Reduction of matrix metalloproteinase 9 (MMP-9) protects motor neurons from TDP-43-triggered death in rNLS8 mice.}, journal = {Neurobiology of disease}, year = {2019}, pmid = {30458231}, doi = {10.1016/j.nbd.2018.11.013}, } @article{pmid30146158, title = {TBK1 Suppresses RIPK1-Driven Apoptosis and Inflammation during Development and in Aging.}, author = {Xu D, Jin T, Zhu H, Chen H, Ofengeim D, Zou C, Mifflin L, Pan L, Amin P, Li W, Shan B, Naito MG, Meng H, Li Y, Pan H, Aron L, Adiconis X, Levin JZ, Yankner BA, Yuan J}, journal = {Cell}, year = {2018}, pmid = {30146158}, doi = {10.1016/j.cell.2018.07.041}, url = {https://pubmed.ncbi.nlm.nih.gov/30146158/}, }