% Bibliography for hypothesis hyp-SDA-2026-04-12-20260411-082446-2c1c9e2d-1 % Title: Multi-Target Hypothesis: Aβ-Induced Cholinergic Damage is Partially Irreversible % Generated: 2026-04-28T15:29:30Z @article{pmid40514243, title = {Increased Neuronal Expression of the Early Endosomal Adaptor APPL1 Replicates Alzheimer's Disease-Related Endosomal and Synaptic Dysfunction with Cholinergic Neurodegeneration.}, author = {Jiang Y, Sachdeva K, Goulbourne CN, Berg MJ, Peddy J, Stavrides PH, Pensalfini A, Pawlik M, Malampati S, Whyte L, Basavarajappa BS, Subbanna S, Bleiwas C, Smiley JF, Mathews PM, Nixon RA}, journal = {The Journal of neuroscience : the official journal of the Society for Neuroscience}, year = {2025}, pmid = {40514243}, doi = {10.1523/JNEUROSCI.2331-24.2025}, url = {https://pubmed.ncbi.nlm.nih.gov/40514243/}, } @article{pmid35418161, title = {Chemical genetic activation of the cholinergic basal forebrain hippocampal circuit rescues memory loss in Alzheimer’s disease}, author = {Weilin Liu, Jianhong Li, Minguang Yang}, journal = {{'name': "Alzheimer's Research & Therapy", 'volume': '14'}}, year = {2022}, pmid = {35418161}, doi = {10.1186/s13195-022-00994-w}, } @article{pmid32473171, title = {Genetic deletion of trpa1 receptor attenuates amyloid beta- 1-42 (aβ1-42)-induced neurotoxicity in the mouse basal forebrain in vivo.}, author = {Maja Payrits, Éva Borbély, Soma Godo}, journal = {{'name': 'Mechanisms of ageing and development', 'pages': '\n 111268\n '}}, year = {2020}, pmid = {32473171}, doi = {10.1016/j.mad.2020.111268}, } @article{pmid33239400, title = {Implications of Oligomeric Amyloid-Beta (oAβ42) Signaling through α7β2-Nicotinic Acetylcholine Receptors (nAChRs) on Basal Forebrain Cholinergic Neuronal Intrinsic Excitability and Cognitive Decline}, author = {Andrew A. George, Jaime M. Vieira, Cameron Xavier-Jackson}, journal = {{'name': 'The Journal of Neuroscience', 'pages': '555 - 575', 'volume': '41'}}, year = {2020}, pmid = {33239400}, doi = {10.1523/jneurosci.0876-20.2020}, } @article{pmid30374941, title = {Removal of p75 Neurotrophin Receptor Expression from Cholinergic Basal Forebrain Neurons Reduces Amyloid-β Plaque Deposition and Cognitive Impairment in Aged APP/PS1 Mice}, author = {Lei Qian, M. Milne, Stephanie R Shepheard}, journal = {{'name': 'Molecular Neurobiology', 'pages': '4639 - 4652', 'volume': '56'}}, year = {2018}, pmid = {30374941}, doi = {10.1007/s12035-018-1404-2}, }