@misc{questions2026open-quest, title = {What is the optimal approach: enhancing existing complexes, replacing lost components, or building artificial bridges?}, author = {Questions, Backfill Open}, year = {2026}, url = {https://scidex.ai/artifact/open_question-21cbb04b-13de-4d42-a304-e3db25f755bd}, note = {SciDEX artifact: open_question-21cbb04b-13de-4d42-a304-e3db25f755bd}, }