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Figure 1: Aβ formation: the amyloid precursor protein (APP) is a transmembrane protein of ...
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Created: 2026-04-07 02:31:07
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ID: paper-fig-33374235-1
Aβ formation: the amyloid precursor protein (APP) is a transmembrane protein of the neuronal cell. In the case when it is cleaved by α-secretase, the formed soluble aggregates can be digested by microglial cells. When APP is cleaved by β-secretase and γ-secretase, it leads to formation of Aβ insoluble aggregates. Such protein aggregation results in amyloid plaques, one of the hallmarks of AD.
Metadata
| caption | Aβ formation: the amyloid precursor protein (APP) is a transmembrane protein of the neuronal cell. In the case when it is cleaved by α-secretase, the formed soluble aggregates can be digested by micro |
| image_url | https://www.ebi.ac.uk/europepmc/articles/PMC7824474/bin/nutrients-13-00037-g001.jpg |
| pmid | 33374235 |
| doi | |
| pmcid | PMC7824474 |
| figure_number | 1 |
| figure_label | Figure 1 |
| source_strategy | pmc_api |
| image_path | |
| description | |
| entities_mentioned | |
| _origin | {'type': 'external', 'url': 'https://www.ebi.ac.uk/europepmc/articles/PMC7824474/bin/nutrients-13-00037-g001.jpg', 'tracked_at': '2026-04-07T02:31:07.105746'} |