Stress granule homeostasis is modulated by TRIM21-mediated ubiquitination of G3BP1 and autophagy-dependent elimination of stress granules.
4 hypothesises
Yang C, Wang Z, Kang Y, Yi Q, Wang T, Bai Y, Liu Y
Autophagy
2023
3 citations
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G3BP1 Is a Tunable Switch that Triggers Phase Separation to Assemble Stress Granules.
5 hypothesises
Yang P, Mathieu C, Kolaitis RM, Zhang P, Messing J, Yurtsever U, Yang Z, Wu J, Li Y, Pan Q
Cell
2020
3 citations
PMID: 32302571
Perivascular cells induce microglial phagocytic states and synaptic engulfment via SPP1 in mouse models of Alzheimer's disease.
4 hypothesises
De Schepper S, Ge JZ, Sierksma A, Crowley G, Ferreira LSS, Garceau D, Toomey CE, Sokolova D, Rueda-Carrasco J, Shin SH
Nat Neurosci
2023
2 citations
PMID: 36747024
Prolonged anesthesia induces neuroinflammation and complement-mediated microglial synaptic elimination involved in neurocognitive dysfunction and anxiety-like behaviors.
3 hypothesises
Xu F, Han L, Wang Y, Deng D, Ding Y, Zhao S, Zhang Q, Ma L, Chen X
BMC Med
2023
2 citations
PMID: 36600274
The P2RY12 receptor promotes VSMC-derived foam cell formation by inhibiting autophagy in advanced atherosclerosis.
3 hypothesises
Pi S, Mao L, Chen J, Shi H, Liu Y, Guo X, Li Y, Zhou L, He H, Yu C
Autophagy
2021
2 citations
PMID: 32160082
TDP-43 Pathology in Alzheimer's Disease.
5 hypothesises
Meneses A, Koga S, O'Leary J, Dickson DW, Bu G, Zhao N
Mol Neurodegener
2021
2 citations
PMID: 34930382
Climate-driven flyway changes and memory-based long-distance migration.
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Nature
2021
2 citations
PMID: 33658718
TDP-43 Triggers Mitochondrial DNA Release via mPTP to Activate cGAS/STING in ALS.
4 hypothesises
Yu CH, Davidson S, Harapas CR, Hilton JB, Mlodzianoski MJ, Laohamonthonkul P, Louis C, Low RRJ, Moecking J, De Nardo D
Cell
2020
2 citations
PMID: 33031745
Functional transcription promoters at DNA double-strand breaks mediate RNA-driven phase separation of damage-response factors.
["Pessina F", "Giavazzi F", "Yin Y", "Gioia U", "Vitelli V", "Galbiati A", "Barozzi S", "Garre M", "Oldani A", "Flaus A"
Nature cell biology
2020
2 citations
PMID: 31570834
miR-130a and Tgfβ Content in Extracellular Vesicles Derived from the Serum of Subjects at High Cardiovascular Risk Predicts their In-Vivo Angiogenic Potential.
["Cavallari C", "Figliolini F", "Tapparo M", "Cedrino M", "Trevisan A", "Positello L", "Rispoli P", "Solini A", "Migliar
Scientific reports
2020
2 citations
PMID: 31959759
A reference map of the human binary protein interactome.
["Luck K", "Kim DK", "Lambourne L", "Spirohn K", "Begg BE", "Bian W", "Brignall R", "Cafarelli T", "Campos-Laborie FJ",
Nature
2020
2 citations
PMID: 32296183
Trehalose induces autophagy via lysosomal-mediated TFEB activation in models of motoneuron degeneration.
6 hypothesises
Rusmini P, Cortese K, Crippa V, Cristofani R, Cicardi ME, Ferrari V, Vezzoli G, Tedesco B, Meroni M, Messi E
Autophagy
2019
2 citations
PMID: 30335591
Common variants on 6q16.2, 12q24.31 and 16p13.3 are associated with major depressive disorder.
["Li X", "Luo Z", "Gu C", "Hall LS", "McIntosh AM", "Zeng Y", "Porteous DJ", "Hayward C", "Li M", "Yao YG", "Zhang C", "
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology
2019
2 citations
PMID: 29728651
Clinical practice guideline: tonsillitis I. Diagnostics and nonsurgical management.
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European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
2016
2 citations
PMID: 26755048
Canonical and atypical E2Fs regulate the mammalian endocycle.
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Nature cell biology
2013
2 citations
PMID: 23064266
Hypoxia-driven phase separation of the PABP1/eIF4B complex forms stress granules and activates ChaC2 translation to promote polyunsaturated lipids-supported peritoneal metastasis in gastric cancer.
1 hypothesis
Lin Z, Gao Y, Zhang Q, Yang S, Chen Y, Ding H, Peng W, Zhang X, Nurzat Y, Hu J
Cancer Lett
2026
1 citations
PMID: 41780839
PAD4 promotes macrophage migration to aggravate tubulointerstitial injury in diabetic kidney disease.
1 hypothesis
Xiong Y, Li R, Chen X, Peng C, Zeng Q, Zhu S, He F, Wu J, Lei J, Chen M
Mol Ther
2026
1 citations
PMID: 41054305
Bergenin attenuates traumatic brain injury via inhibition of microglial PFKFB3-driven glycolytic-inflammatory crosstalk.
1 hypothesis
Sun B, Zhang A, Feng S, Jamali AW, Jia Z, Xu Y, Wang Z, Zhao J, Sun G, Liu L
Int Immunopharmacol
2026
1 citations
PMID: 41520557
Tau and MAP6 establish labile and stable domains on microtubules.
1 hypothesis
Kirimtay K, Huang W, Sun X, Qiang L, Wang DV, Sprouse CT, Craig EM, Baas PW
iScience
2025
1 citations
PMID: 40040809