Mediterranean diet app intervention for atrial fibrillation patients

Clinical Score: 0.950 Price: $0.50 atrial fibrillation human patients Status: proposed

What This Experiment Tests

Clinical experiment designed to assess clinical efficacy targeting N/A in human patients. Primary outcome: feasibility (retention rate) and inflammatory biomarkers

Description

This single-arm pre-post pilot study evaluated the feasibility and preliminary effects of a Mediterranean diet self-monitoring mobile application (Olitor) in patients with symptomatic paroxysmal atrial fibrillation. Participants used the app for 3 months, which prompted weekly diet tracking and provided tailored feedback based on Mediterranean diet principles. The study assessed multiple outcomes including inflammatory biomarkers (interleukin-6 and C-reactive protein), atrial fibrillation symptoms, quality of life measures, physical activity levels, diet knowledge, self-efficacy, and body mass index. The intervention aimed to reduce inflammation through dietary modification, potentially improving symptom burden and quality of life in AF patients. Results showed promising trends with reductions in inflammatory markers, improvements in quality of life (particularly in the family QoL subdomain with large effect size), increased walking activity, and gains in self-efficacy and diet knowledge. The study demonstrated good retention rates and feasibility of the digital health intervention approach.

TARGET GENE
N/A
MODEL SYSTEM
human patients
ESTIMATED COST
$0
TIMELINE
0 months
PATHWAY
inflammatory pathways
SOURCE
extracted_from_pmid_41945364
PRIMARY OUTCOME
feasibility (retention rate) and inflammatory biomarkers

Scoring Dimensions

Info Gain 0.00 (25%) Feasibility 0.00 (20%) Hyp Coverage 0.00 (20%) Cost Effect. 0.00 (15%) Novelty 0.00 (10%) Ethical Safety 0.00 (10%) 0.950 composite

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Biomarkersindex

Protocol

3-month single-arm pre-post pilot study using Olitor Mediterranean diet app with weekly diet tracking and tailored feedback, measuring outcomes at baseline and 3 months

Expected Outcomes

Reduced inflammation, improved AF symptoms and quality of life through Mediterranean diet adherence

Success Criteria

Good retention rates, reductions in inflammatory markers, improvements in quality of life measures

Related Hypotheses (0)

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