Transradial vs transfemoral approach in dialysis patients undergoing PCI

Clinical Score: 0.900 Price: $0.50 cardiovascular disease requiring percutaneous coronary intervention dialysis patients undergoing cardiac catheterization Status: proposed

What This Experiment Tests

Clinical experiment designed to assess clinical efficacy targeting N/A in dialysis patients undergoing cardiac catheterization. Primary outcome: in-hospital and 30-day mortality rates

Description

A prospective observational study comparing the safety and efficacy of transradial approach (TRA) versus transfemoral approach (TFA) in patients on dialysis undergoing cardiac catheterization and percutaneous coronary intervention. The study aimed to construct a TRA system specifically for dialysis patients and evaluate its safety profile. Patients were divided into two groups based on access site selection, with radial access limited to the opposite side of arteriovenous fistula. The study evaluated clinical outcomes including mortality, bleeding complications, procedural success rates, and radial artery occlusion rates to determine if TRA could be safely implemented in this high-risk population.

TARGET GENE
N/A
MODEL SYSTEM
dialysis patients undergoing cardiac catheterization
ESTIMATED COST
$0
TIMELINE
0 months
PATHWAY
N/A
SOURCE
extracted_from_pmid_29335385
PRIMARY OUTCOME
in-hospital and 30-day mortality rates

Scoring Dimensions

Info Gain 0.00 (25%) Feasibility 0.00 (20%) Hyp Coverage 0.00 (20%) Cost Effect. 0.00 (15%) Novelty 0.00 (10%) Ethical Safety 0.00 (10%) 0.900 composite

Protocol

Prospective observational study where 88 consecutive dialysis patients undergoing cardiac catheterization were divided into TRA group (n=62) or TFA group (n=26) based on access site. Radial access was performed on the opposite side of arteriovenous fistula. Patients were followed for procedural success, complications, bleeding events, and radial artery occlusion.

Expected Outcomes

TRA would demonstrate comparable safety to TFA with potentially reduced bleeding complications in dialysis patients

Success Criteria

Low mortality rates, acceptable procedural success rate (>95%), low bleeding complication rates, and acceptable radial artery occlusion rates

Related Hypotheses (0)

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