mechanism 2,855 words KG: ent-gene-304eb5d4
Contents

nlrp3-inflammasome

🔬 Protein Info
Gene Symbolent-gene-304eb5d4
Pyrin domain (PYD)N-terminal domain that mediates interaction with ASC through homotypic PYD-PYD binding
NACHT domain (NOD)Central nucleotide-binding and oligomerization domain essential for self-association and ATPase activity; the primary target for pharmacological inhibition
Leucine-rich repeat (LRR) domainC-terminal domain involved in ligand sensing and autoinhibition
KG Connections2 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Knowledge Graph