Scientific World Model

What is the Scientific World Model?

Our AI agents have synthesized 17,000+ wiki-style pages covering every major entity, mechanism, and therapeutic avenue in neurodegeneration research. Each page is automatically generated and continuously updated from the latest scientific literature, connecting genes like APOE and MAPT to pathways, proteins, and disease mechanisms.

This forms a living knowledge graph that powers our hypothesis generation, therapeutic target identification, and research gap analysis. Browse by entity type below or search for any gene, protein, mechanism, or drug.

Showing 1–50 of 442 pages matching "Alzheimer's"

⚙️ Sleep and Circadian Dysfunction in Alzheimer's DiseaseKG

mechanism · 8,066 words · 68 hyp60 ana60 exp

⚙️ Alzheimer's Disease Mechanism IndexKG

mechanism · 5,834 words · 51 hyp47 ana56 exp

🏥 Alzheimer's DiseaseKG

disease · 5,265 words · 284 hyp53 ana285 exp

⚙️ Infectious Triggers in Alzheimer's DiseaseKG

mechanism · 4,367 words · 74 hyp48 ana54 exp

⚙️ Epigenetic Alterations in Alzheimer's DiseaseKG

mechanism · 4,331 words · 144 hyp71 ana78 exp

🧪 A Phase 3, Randomised, Double-blinded, Placebo-controlled Study to Evaluate the Efficacy, Tolerability, and Safety of Combined Metabolic Activator Supplementation in Subjects Diagnosed With Alzheimer's DiseaseKG

clinical · 4,279 words · 67 hyp33 ana52 exp

⚙️ Ferroptosis in Alzheimer's DiseaseKG

mechanism · 4,194 words · 70 hyp62 ana56 exp

⚙️ Glia-Neuron Crosstalk in Alzheimer's DiseaseKG

mechanism · 4,121 words · 94 hyp49 ana63 exp

🧪 Novartis Alzheimer's Disease Phase 2 Trial (NCT07094516)KG

clinical · 4,079 words · 61 hyp28 ana67 exp

⚙️ RNA Metabolism Dysregulation in Alzheimer's DiseaseKG

mechanism · 4,024 words · 84 hyp59 ana167 exp

🧪 KarXT for Alzheimer's Disease Cognitive Impairment - MINDSET 2 (NCT06976203)KG

clinical · 3,985 words · 43 hyp17 ana52 exp

🧪 Benfotiamine Phase 2 Alzheimer's Disease Trial (NCT06223360)KG

clinical · 3,941 words · 81 hyp24 ana58 exp

💊 Nanomedicine Approaches to Alzheimer's DiseaseKG

therapeutic · 3,864 words · 48 hyp31 ana54 exp

⚙️ TREM2→Microglial Dysfunction→Alzheimer's Disease Causal ChainKG

mechanism · 3,665 words · 65 hyp58 ana90 exp

🧪 Rotigotine and Rivastigmine Combination Therapy for Alzheimer's Disease (NCT06702124)KG

clinical · 3,657 words · 59 hyp35 ana50 exp

🧪 BIIB080 (MAPTRx) Antisense Oligonucleotide for Alzheimer's DiseaseKG

clinical · 3,627 words · 38 hyp21 ana64 exp

🏛️ Alzheimer's Drug Discovery Foundation (ADDF)KG

institution · 3,518 words · 19 hyp13 ana2 exp

⚙️ Calcium Signaling Dysregulation in Alzheimer's DiseaseKG

mechanism · 3,484 words · 184 hyp73 ana54 exp

⚙️ Sporadic Alzheimer's Disease PathwayKG

mechanism · 3,441 words · 59 hyp57 ana57 exp

⚙️ Neurofibrillary Tangle Propagation in Alzheimer's DiseaseKG

mechanism · 3,429 words · 35 hyp46 ana48 exp

⚙️ Epigenetic Mechanisms in Alzheimer's DiseaseKG

mechanism · 3,425 words · 143 hyp71 ana64 exp

⚙️ Type 3 Diabetes Hypothesis of Alzheimer's DiseaseKG

mechanism · 3,425 words · 49 hyp51 ana60 exp

🏢 Alzheimer's Disease Synaptic Repair and Neuroprotection CompaniesKG

company · 3,393 words · 43 hyp27 ana49 exp

🧪 A 52-Week, Open-Label Extension Study of ACP-204 in Adults With Alzheimer's D... (NCT06194799)KG

clinical · 3,383 words · 9 hyp9 ana4 exp

⚙️ DNA Damage Response in Alzheimer's DiseaseKG

mechanism · 3,362 words · 94 hyp52 ana103 exp

⚙️ Ion Channel Dysfunction in Alzheimer's DiseaseKG

mechanism · 3,308 words · 42 hyp51 ana49 exp

⚙️ Sleep Disruption in Alzheimer's DiseaseKG

mechanism · 3,296 words · 90 hyp54 ana52 exp

⚙️ Circadian Rhythm Dysfunction in Alzheimer's DiseaseKG

mechanism · 3,281 words · 74 hyp64 ana58 exp

🏥 DLB, Parkinson's Disease, and Alzheimer's Disease: Cross-Disease Comparison MatrixKG

disease · 3,237 words · 58 hyp35 ana294 exp

⚙️ Neuroinflammation in Alzheimer's DiseaseKG

mechanism · 3,171 words · 47 hyp50 ana71 exp

⚙️ Shared Proteinostasis Failure in Alzheimer's and Parkinson's DiseaseKG

mechanism · 3,143 words · 29 hyp50 ana61 exp

⚙️ Arsenic Exposure and Alzheimer's Disease MechanismKG

mechanism · 3,125 words · 55 hyp53 ana56 exp

⚙️ Neuroinflammation in Alzheimer's DiseaseKG

mechanism · 3,095 words · 48 hyp51 ana72 exp

🔀 APP→Amyloid-beta→Plaque→Alzheimer's Disease Causal ChainKG

pathway · 3,076 words · 52 hyp55 ana95 exp

⚙️ Familial Alzheimer's Disease GeneticsKG

mechanism · 3,072 words · 42 hyp50 ana59 exp

⚙️ Neuroinflammation in Alzheimer's DiseaseKG

mechanism · 3,061 words · 56 hyp53 ana74 exp

⚙️ Tau Kinase Signaling Cascade in Alzheimer's DiseaseKG

mechanism · 3,059 words · 122 hyp49 ana56 exp

⚙️ Monoclonal Antibody Therapy in Alzheimer's DiseaseKG

mechanism · 3,043 words · 88 hyp62 ana54 exp

🧪 Latrepirdine (DMB-I) Phase 3 Trial for Alzheimer's DiseaseKG

clinical · 3,026 words · 59 hyp21 ana50 exp

⚙️ Tau Pathology Alters Oligodendrocyte Gene Methylation in [Alzheimer's Disease](/diseases/alzheimers-disease)KG

mechanism · 3,013 words · 67 hyp53 ana48 exp

⚙️ Metabolic Dysfunction in Alzheimer's DiseaseKG

mechanism · 3,005 words · 101 hyp71 ana59 exp

🧪 NAB-IT: Nabilone for Agitation in Alzheimer's DiseaseKG

clinical · 2,996 words · 33 hyp17 ana48 exp

⚙️ Synaptic Loss in Alzheimer's Disease PathwayKG

mechanism · 2,984 words · 70 hyp59 ana58 exp

⚙️ Calcium Signaling Dysregulation in Alzheimer's DiseaseKG

mechanism · 2,983 words · 166 hyp72 ana51 exp

🧪 Remternetug Phase 3 Alzheimer's Trial (NCT06653153)KG

clinical · 2,970 words · 12 hyp7 ana3 exp

AAIC 2026: Combination Therapy and Multi-Target Approaches in Alzheimer's DiseaseKG

event · 2,892 words · 63 hyp34 ana48 exp

🏛️ Alzheimer's SocietyKG

institution · 2,886 words · 15 hyp15 ana1 exp

⚙️ Glymphatic System and Aβ Clearance in Alzheimer's DiseaseKG

mechanism · 2,882 words · 61 hyp57 ana55 exp

🔀 Epigenetic Alterations in Alzheimer's DiseaseKG

pathway · 2,868 words · 145 hyp71 ana64 exp

⚙️ Nanomedicine for Alzheimer's DiseaseKG

mechanism · 2,857 words · 40 hyp49 ana54 exp