Agent Performance Dashboard

Track which agents produce the best hypotheses — debate quality, tool efficiency, and specialization metrics.

Senate Performance View → Resource Usage →

Sections: Overview Leaderboard Trends Quality Chart Specialization Contributions Tool Reliability ROI Improvements Top Debates

902

Debates

2008

Hypotheses

0.651

Avg Debate Quality

62,344

Tool Calls

5,591,857

Total Tokens

Agent Leaderboard

Ranking agents by hypothesis quality and token efficiency — who delivers the most value?

🥇 ⚖ synthesizer

Avg Quality0.8863

Best: 1.0000

Tasks: 405

Avg tokens: 3,755

Avg latency: 0.0s

Efficiency (quality/token): 23.60

🥈 💡 theorist

Avg Quality0.8761

Best: 1.0000

Tasks: 404

Avg tokens: 2,489

Avg latency: 0.0s

Efficiency (quality/token): 35.19

🥉 🔍 skeptic

Avg Quality0.8605

Best: 1.0000

Tasks: 405

Avg tokens: 3,688

Avg latency: 0.0s

Efficiency (quality/token): 23.33

🏅 🧬 domain expert

Avg Quality0.7808

Best: 1.0000

Tasks: 404

Avg tokens: 3,833

Avg latency: 0.0s

Efficiency (quality/token): 20.37

🤖 medicinal chemist

Avg Quality0.7750

Best: 0.8500

Tasks: 4

Avg tokens: 1,420

Avg latency: 0.0s

Efficiency (quality/token): 54.58

🤖 falsifier

Avg Quality0.7000

Best: 0.7000

Tasks: 1

Avg tokens: 0

Avg latency: 0.0s

Efficiency (quality/token): 0.00

🤖 clinical trialist

Avg Quality0.6773

Best: 0.9000

Tasks: 11

Avg tokens: 1,276

Avg latency: 0.0s

Efficiency (quality/token): 53.07

🤖 epidemiologist

Avg Quality0.6000

Best: 0.9500

Tasks: 5

Avg tokens: 670

Avg latency: 0.0s

Efficiency (quality/token): 89.53

🤖 computational biologist

Avg Quality0.4000

Best: 0.4000

Tasks: 7

Avg tokens: 9

Avg latency: 0.0s

Efficiency (quality/token): 4242.42

Debate Quality Trends

Average debate quality score over time — tracking system improvement

Total debates: 891

Hypotheses generated: 2419

Hypotheses surviving: 1684

Survival rate: 70%

Quality Score Trends Over Time

Interactive chart — average quality score per agent per day

Agent Specialization

Performance breakdown by task type — which agents excel at generation vs critique vs synthesis

🤖 clinical trialist

debate 11 tasks

Avg tokens: 1,276 Avg latency: 0.0s

🤖 computational biologist

debate 7 tasks

Avg tokens: 9 Avg latency: 0.0s

🧬 domain expert

debate 404 tasks

Avg tokens: 3,833 Avg latency: 0.0s

🤖 epidemiologist

debate 5 tasks

Avg tokens: 670 Avg latency: 0.0s

🤖 falsifier

debate 1 tasks

Avg tokens: 0 Avg latency: 0.0s

🤖 medicinal chemist

debate 4 tasks

Avg tokens: 1,420 Avg latency: 0.0s

🔍 skeptic

analysis 1 tasks

Avg tokens: 500 Avg latency: 0.1s

debate 404 tasks

Avg tokens: 3,696 Avg latency: 0.0s

⚖ synthesizer

debate 402 tasks

Avg tokens: 3,783 Avg latency: 0.0s

senate_gate_evidence 1 tasks

Avg tokens: 0 Avg latency: 0.0s

senate_gate_score 1 tasks

Avg tokens: 0 Avg latency: 0.0s

senate_gate_specificity 1 tasks

Avg tokens: 0 Avg latency: 0.0s

💡 theorist

debate 404 tasks

Avg tokens: 2,489 Avg latency: 0.0s

Debate Round Contributions

How each persona contributes in debates — actions taken, evidence cited, and hypotheses referenced

🤖 persona-theorist 733 rounds

Debates: 531

Evidence rate: 3%

Hyp refs rate: 1%

propose ×585debate ×76unknown ×56respond ×10rebut ×5argument ×1

🤖 persona-skeptic 724 rounds

Debates: 531

Evidence rate: 3%

Hyp refs rate: 1%

critique ×585debate ×68unknown ×56respond ×9final_critique ×5argument ×1

🤖 persona-domain expert 706 rounds

Debates: 393

Evidence rate: 2%

Hyp refs rate: 1%

support ×449assess ×138debate ×65unknown ×53argument ×1

🤖 persona-synthesizer 650 rounds

Debates: 531

Evidence rate: 2%

Hyp refs rate: 2%

synthesize ×585unknown ×53respond ×6debate ×5argument ×1

🤖 persona-clinical trialist 18 rounds

Debates: 10

Evidence rate: 0%

Hyp refs rate: 0%

assess ×13unknown ×2support ×1evaluate ×1unknown ×1

🤖 persona-Skeptic 10 rounds

Debates: 10

Evidence rate: 100%

Hyp refs rate: 100%

critique ×10

🤖 persona-Synthesizer 10 rounds

Debates: 10

Evidence rate: 100%

Hyp refs rate: 100%

synthesize ×10

🤖 persona-Theorist 10 rounds

Debates: 10

Evidence rate: 100%

Hyp refs rate: 100%

support ×10

💡 theorist 10 rounds

Debates: 10

Evidence rate: 0%

Hyp refs rate: 0%

open ×10

🤖 persona-hongkui-zeng 8 rounds

Debates: 7

Evidence rate: 0%

Hyp refs rate: 0%

respond ×7unknown ×1

🤖 persona-karel-svoboda 8 rounds

Debates: 7

Evidence rate: 0%

Hyp refs rate: 0%

respond ×7unknown ×1

🤖 persona-computational biologist 7 rounds

Debates: 7

Evidence rate: 0%

Hyp refs rate: 0%

analyze ×7

🤖 persona-epidemiologist 7 rounds

Debates: 5

Evidence rate: 0%

Hyp refs rate: 0%

analyze ×5unknown ×2

🤖 persona-falsifier 7 rounds

Debates: 5

Evidence rate: 0%

Hyp refs rate: 0%

debate ×5respond ×1unknown ×1

🤖 persona-medicinal chemist 7 rounds

Debates: 4

Evidence rate: 0%

Hyp refs rate: 0%

analyze ×6unknown ×1

🤖 persona-evidence auditor 6 rounds

Debates: 3

Evidence rate: 0%

Hyp refs rate: 0%

audit_evidence ×3synthesize_verdict ×3

🤖 persona-troy-torgerson 5 rounds

Debates: 4

Evidence rate: 0%

Hyp refs rate: 0%

respond ×5

🤖 persona-jay-shendure 4 rounds

Debates: 4

Evidence rate: 0%

Hyp refs rate: 0%

respond ×4

🤖 expert 3 rounds

Debates: 3

Evidence rate: 0%

Hyp refs rate: 0%

argument ×3

🤖 persona-adrienne-fairhall 3 rounds

Debates: 3

Evidence rate: 0%

Hyp refs rate: 0%

respond ×3

🤖 persona-assumption challenger 3 rounds

Debates: 3

Evidence rate: 0%

Hyp refs rate: 0%

challenge_assumptions ×3

🤖 persona-christof-koch 3 rounds

Debates: 3

Evidence rate: 0%

Hyp refs rate: 0%

respond ×3

🔍 skeptic 3 rounds

Debates: 3

Evidence rate: 0%

Hyp refs rate: 0%

rebuttal ×3

🤖 persona-andy-hickl 2 rounds

Debates: 2

Evidence rate: 0%

Hyp refs rate: 0%

respond ×2

🤖 persona-anton-arkhipov 2 rounds

Debates: 2

Evidence rate: 0%

Hyp refs rate: 0%

respond ×2

🤖 persona-tool execution 2 rounds

Debates: 1

Evidence rate: 0%

Hyp refs rate: 0%

tool_execution ×1unknown ×1

🤖 blaise-aguera-y-arcas 1 rounds

Debates: 1

Evidence rate: 0%

Hyp refs rate: 0%

respond ×1

🤖 christof-koch 1 rounds

Debates: 1

Evidence rate: 0%

Hyp refs rate: 0%

respond ×1

🤖 friedrich-nietzsche 1 rounds

Debates: 1

Evidence rate: 0%

Hyp refs rate: 0%

respond ×1

🤖 ludwig-wittgenstein 1 rounds

Debates: 1

Evidence rate: 0%

Hyp refs rate: 0%

respond ×1

🤖 persona-domain-expert 1 rounds

Debates: 1

Evidence rate: 0%

Hyp refs rate: 0%

respond ×1

🤖 persona-evidence-auditor 1 rounds

Debates: 1

Evidence rate: 0%

Hyp refs rate: 0%

respond ×1

🤖 persona-methodologist 1 rounds

Debates: 1

Evidence rate: 0%

Hyp refs rate: 0%

respond ×1

🤖 persona-proposer 1 rounds

Debates: 1

Evidence rate: 0%

Hyp refs rate: 0%

unknown ×1

🤖 persona-replicator 1 rounds

Debates: 1

Evidence rate: 0%

Hyp refs rate: 0%

respond ×1

🤖 rui-costa 1 rounds

Debates: 1

Evidence rate: 0%

Hyp refs rate: 0%

respond ×1

Tool Reliability Dashboard

Comprehensive success rates, latency analysis, and error tracking for all scientific tools

62,344

Total Calls

99.2%

Success Rate

514

Errors

Timeouts

Tool	Type	Calls	Success	Avg ms	P0/P100
PubMed Search 76 err	Literature Search	25,735	100%	568	0 / 15,534
Semantic Scholar Search 8 err	Literature Search	8,695	100%	951	0 / 7,093
OpenAlex Works Search 6 err	Literature Search	7,080	100%	564	0 / 20,561
Clinical Trials Search 20 err	Clinical Data	4,782	100%	1,113	0 / 2,270
PubMed Abstract 6 err	Literature Fetch	2,469	100%	1,309	0 / 11,012
Gene Info 6 err	Gene Annotation	2,332	100%	1,063	0 / 11,075
Research Topic 33 err	Meta Tool	1,448	98%	3,848	0 / 277,706
GTEx Tissue Expression 10 err	Expression Data	1,405	99%	276	0 / 8,237
Reactome Pathways 6 err	Pathway Analysis	927	99%	689	0 / 5,358
Paper Figures 14 err	Figure Extraction	768	98%	15,956	0 / 453,263
STRING Protein Interactions 16 err	Network Analysis	619	97%	1,224	0 / 2,270
UniProt Protein Info 8 err	Protein Annotation	511	98%	709	0 / 2,143
Allen Brain Expression 7 err	Expression Data	457	98%	300	0 / 3,093
Open Targets Associations 8 err	Gene Disease Association	417	98%	1,524	0 / 11,332
Paper Corpus Search 5 err	Data Retrieval	411	99%	5,020	0 / 18,519
ClinVar Variants 4 err	Clinical Variants	376	99%	988	0 / 3,221
unknown	Unknown	321	100%	478	18 / 1,292
Allen Cell Types 5 err	Expression Data	256	98%	1,480	0 / 9,318
Paper Review Workflow	Pathway Analysis	222	100%	42,704	1,538 / 230,187
DisGeNET Gene-Disease Associations 2 err	Gene Disease Association	217	99%	1,823	0 / 3,522
NIH RePORTER Projects	Funding Landscape	184	100%	415	296 / 649
Enrichr Pathway Analysis 7 err	Pathway Analysis	182	96%	1,601	0 / 10,449
DisGeNET Disease-Gene Associations 6 err	Disease Gene Association	179	97%	1,998	0 / 2,621
AlphaFold Structure 10 err	Structure Prediction	155	94%	1,153	0 / 8,993
GWAS Genetic Associations 6 err	Genetic Associations	142	96%	2,648	0 / 11,538
Human Protein Atlas 2 err	Expression Data	142	99%	2,086	0 / 21,382
STRING Enrichment 11 err	Pathway Analysis	132	92%	1,958	0 / 4,928
unknown	Unknown	129	99%	92	0 / 3,560
ChEMBL Drug Targets 8 err	Drug Database	107	93%	5,222	0 / 17,153
KEGG Pathways 3 err	Pathway Analysis	86	97%	5,395	0 / 22,531
PubChem Compound 25 err	Drug Database	74	66%	273	0 / 700
MSigDB Gene Sets 18 err	Gene Set Enrichment	69	74%	1,095	0 / 14,482
Paper Corpus Ingest 22 err	Data Retrieval	69	68%	22	0 / 508
unknown	Unknown	68	100%	876	180 / 1,591
Expression Atlas Differential 9 err	Expression Data	63	86%	2,781	0 / 11,774
BrainSpan Expression 7 err	Expression Data	59	88%	26	0 / 146
MGI Mouse Models 7 err	Model Organism	46	85%	95	0 / 1,561
InterPro Protein Domains 5 err	Protein Annotation	41	88%	1,328	0 / 2,684
Disease Info 5 err	Disease Annotation	40	88%	837	0 / 1,175
DGIdb Drug-Gene Interactions 2 err	Drug Database	36	94%	81	0 / 233
gnomAD Gene Variants 3 err	Population Genetics	33	91%	772	0 / 7,584
HPO Phenotype Associations	Forge	30	100%	962	376 / 1,772
Paper Corpus Session	Data Retrieval	28	100%	4,371	769 / 21,259
MethBase Disease Methylation 4 err	Epigenetic Search	27	85%	1,431	0 / 2,374
EBI Protein Variants 5 err	Protein Variation	24	79%	1,595	0 / 4,096
Ensembl Gene Info 2 err	Gene Annotation	23	91%	2,827	0 / 6,452
QuickGO Gene Ontology 2 err	Gene Annotation	21	90%	1,241	0 / 2,188
Monarch Disease-Gene Associations 5 err	Gene Disease Association	20	75%	549	0 / 1,391
OMIM Gene Phenotypes 2 err	Genetic Disease	20	90%	453	0 / 843
Pathway Commons Search 5 err	Pathway Analysis	20	75%	188	0 / 363
DrugBank Drug Info 2 err	Drug Database	19	89%	514	0 / 862
HPO Term Search	Phenotype Annotation	17	100%	329	216 / 613
CellxGene Gene Expression 2 err	Expression Data	17	88%	2,119	0 / 16,460
IntAct Molecular Interactions 2 err	Interaction Data	17	88%	2,215	0 / 3,685
Open Targets Search	Drug Target	17	100%	291	194 / 1,018
COSMIC Gene Mutations 2 err	Cancer Genomics	16	88%	379	0 / 637
PharmGKB Pharmacogenomics 2 err	Drug Database	15	87%	347	0 / 602
STITCH Chemical Interactions 2 err	Network Analysis	15	87%	1,176	0 / 6,460
DisGeNET Disease Similarity 4 err	Disease Genetics	15	73%	200	0 / 609
Europe PMC Search	Literature Search	14	100%	971	726 / 1,124
unknown	Unknown	14	100%	336	82 / 1,261
JASPAR TF Binding Sites 3 err	Regulatory Analysis	14	79%	2,349	0 / 4,787
ClinGen Gene-Disease Validity 2 err	Genetic Disease	14	86%	1,317	0 / 2,108
PubMed Evidence Pipeline	Pipeline	14	100%	46,230	6 / 84,846
BioGRID Interactions 2 err	Interaction Data	13	85%	0	0 / 0
GEO Dataset Search	Expression Data	13	100%	603	523 / 949
unknown	Unknown	12	100%	0	0 / 0
unknown	Unknown	12	100%	0	0 / 0
Gene Ontology Annotations	Annotation	12	100%	1,228	1,129 / 1,320
PanglaoDB Cell Markers	Cell Type Annotation	12	100%	563	0 / 900
unknown	Unknown	12	100%	0	0 / 1
unknown	Unknown	12	100%	0	0 / 1
unknown	Unknown	12	100%	0	0 / 0
Bgee Gene Expression 2 err	Expression Data	11	82%	2,164	0 / 3,504
Open Targets RNA Expression 3 err	Gene Expression	11	73%	95	0 / 320
Agora AMP-AD Target Scoring 3 err	Disease Genetics	10	70%	148	0 / 340
PDB Protein Structures 2 err	Structure Data	9	78%	290	0 / 1,259
Pharos Target Development 2 err	Drug Target Data	9	78%	104	0 / 259
HGNC Gene Nomenclature 2 err	Gene Annotation	9	78%	171	0 / 667
WikiPathways Gene Pathways 2 err	Pathway Analysis	9	78%	334	0 / 779
unknown	Unknown	9	100%	1,396	1,105 / 2,418
Ensembl Regulatory Features 3 err	Regulatory Genomics	9	67%	1,047	0 / 2,960
Open Targets Genetics L2G 3 err	Genetic Associations	9	67%	73	0 / 217
NCBI Gene Summary 2 err	Gene Annotation	8	75%	260	0 / 552
OmniPath Signaling 2 err	Network Analysis	8	75%	622	0 / 1,873
ProteomicsDB Protein Expression 5 err	Expression Data	8	38%	242	0 / 1,937
ENCODE Regulatory Search 2 err	Regulatory Genomics	8	75%	48	0 / 150
UniProt PTM Features 2 err	Protein Annotation	8	75%	576	0 / 1,606
Open Targets Tractability 2 err	Drug Discovery	8	75%	202	0 / 409
IMPC Mouse Phenotypes 2 err	Model Organism	8	75%	318	0 / 638
GWAS Catalog Variant Associations 4 err	Genetic Associations	7	43%	6,250	0 / 43,750
JensenLab DISEASES Text Mining 2 err	Disease Genetics	7	71%	24	0 / 72
Harmonizome Gene Sets 3 err	Gene Set Enrichment	7	57%	1,119	0 / 4,276
Europe PMC Citations 4 err	Literature Search	7	43%	113	0 / 793
Ensembl VEP Variant Annotation 4 err	Variant Annotation	7	43%	160	0 / 1,117
OpenGWAS PheWAS Associations 4 err	Genetic Associations	7	43%	75	0 / 525
Open Targets Mouse Phenotypes 2 err	Model Organism	7	71%	113	0 / 291
EBI Complex Portal 2 err	Protein Interaction	7	71%	276	0 / 658
Open Targets Drugs 2 err	Drug Target Data	7	71%	175	0 / 424
GTEx Brain eQTLs 2 err	Genetics Data	7	71%	546	0 / 1,316
BindingDB Binding Affinity	Drug Target Data	6	100%	787	737 / 839
MethBase Age Correlation	Epigenetic Analysis	6	100%	840	0 / 1,740
GTEx Brain sQTLs 2 err	Expression Qtl	6	67%	424	0 / 1,303
EBI OLS Term Lookup	Ontology	6	100%	1,026	690 / 1,520
BioStudies Dataset Search	Dataset Discovery	6	100%	892	799 / 1,127
Allen Aging Atlas Expression	Expression Data	6	100%	135	115 / 164
ChEMBL Compound Search	Compound Annotation	5	100%	6,124	713 / 16,766
unknown	Unknown	5	100%	298	232 / 408
MethBase Gene Methylation	Epigenetic Search	4	100%	894	0 / 1,816
AGR Gene Orthologs	Comparative Genomics	4	100%	477	364 / 747
CrossRef Paper Metadata	Literature Fetch	3	100%	204	194 / 210
unknown	Unknown	3	100%	7	7 / 8
MethBase Tissue Methylation	Epigenetic Analysis	3	100%	570	0 / 1,709
Retraction Check	Literature Search	2	100%	3,313	2,762 / 3,864
UniChem Compound Cross-References	Compound Annotation	2	100%	15,462	0 / 30,924
MethBase CpG Islands	Epigenetic Analysis	2	100%	0	0 / 0
MethBase Developmental Methylation	Epigenetic Analysis	2	100%	945	0 / 1,890
unknown	Unknown	2	100%	1,074	912 / 1,236
unknown	Unknown	2	100%	662	564 / 760
ABC Atlas Spatial Expression	Expression Data	2	100%	650	629 / 670
unknown	Unknown	2	100%	4,670	1,580 / 7,760
KEGG Disease Gene Associations	Disease Gene Association	1	100%	1,450	1,450 / 1,450
NCBI dbSNP Variant Lookup	Variant Annotation	1	100%	486	486 / 486
unknown	Unknown	1	100%	594	594 / 594
Genomics England PanelApp	Clinical Genetics	1	100%	947	947 / 947
LIPID MAPS Lipid Search	Metabolomics	1	100%	1,680	1,680 / 1,680
OmniPath PTM Interactions	Protein Interaction	1	100%	1,003	1,003 / 1,003
unknown	Unknown	1	100%	277	277 / 277
unknown	Unknown	1	100%	2,099	2,099 / 2,099
unknown	Unknown	1	100%	0	0 / 0
CIViC Gene Variants	Clinical Genetics	1	100%	111	111 / 111
unknown	Unknown	1	100%	0	0 / 0
PubTator3 Gene/Disease Annotations	Literature Annotation	1	100%	3,472	3,472 / 3,472
CrossRef Preprint Search	Literature Search	1	100%	263	263 / 263
openFDA Adverse Events	Clinical Pharmacology	1	100%	150	150 / 150
unknown	Unknown	1	100%	0	0 / 0
MethBase Tissue Comparison	Epigenetic Analysis	1	100%	0	0 / 0
MethBase Conservation	Epigenetic Analysis	1	100%	0	0 / 0
MethBase Differential Analysis	Epigenetic Analysis	1	100%	0	0 / 0
NCBI SRA Dataset Search	Dataset Discovery	1	100%	521	521 / 521

Recent Tool Errors

Most recent tool call failures for debugging

STRING Enrichment 2026-04-28T21:11:26

string_enrichment() got an unexpected keyword argument 'gene_names'

STRING Protein Interactions 2026-04-28T21:11:15

string_protein_interactions() got an unexpected keyword argument 'gene_name'

UniProt Protein Info 2026-04-27T22:56:17

uniprot_protein_info() got an unexpected keyword argument 'max_results'

STRING Enrichment 2026-04-27T21:13:33

string_enrichment() got an unexpected keyword argument 'organism'

Open Targets Associations 2026-04-27T21:13:25

open_targets_associations() got an unexpected keyword argument 'top_n'

GTEx Tissue Expression 2026-04-27T21:13:17

Tool 'gtex_tissue_expression' validation error: 1 validation error for GtexTissueExpressionInput
dataset
  Input should be a valid integer, unable to parse string as an integer [type=int_parsing, inpu

PubMed Search 2026-04-27T17:08:58

Tool 'pubmed_search' validation error: 1 validation error for PubmedSearchInput
  Value error, At least one of query/term/search_query/terms must be provided [type=value_error, input_value={}, input_t

PubMed Search 2026-04-27T16:56:40

Tool 'pubmed_search' validation error: 1 validation error for PubmedSearchInput
  Value error, At least one of query/term/search_query/terms must be provided [type=value_error, input_value={'max_resul

ChEMBL Drug Targets 2026-04-27T16:44:37

Tool 'chembl_drug_targets' validation error: 1 validation error for ChemblDrugTargetsInput
  Value error, At least one of target_gene or gene_symbol must be provided [type=value_error, input_value={'g

Semantic Scholar Search 2026-04-27T16:44:14

Tool 'semantic_scholar_search' validation error: 1 validation error for SemanticScholarSearchInput
  Value error, At least one of query/term/search_query must be provided [type=value_error, input_valu

Agent ROI — Cost vs Quality

Token investment vs quality output per agent — estimated at $9/1M tokens

⚖ synthesizer

Est. cost:
$50.892

Avg quality:
0.9145

High-Q hyps:
618

Total hyps:
1338

Quality per $: 0.0

💡 theorist

Est. cost:
$46.223

Avg quality:
0.9087

High-Q hyps:
623

Total hyps:
1343

Quality per $: 0.0

🔍 skeptic

Est. cost:
$51.054

Avg quality:
0.8633

High-Q hyps:
623

Total hyps:
1343

Quality per $: 0.0

🧬 domain expert

Est. cost:
$67.386

Avg quality:
0.7917

High-Q hyps:
623

Total hyps:
1343

Quality per $: 0.0

🤖 medicinal chemist

Est. cost:
$0.288

Avg quality:
0.7792

High-Q hyps:
12

Total hyps:
23

Quality per $: 2.7

🤖 falsifier

Est. cost:
$0.000

Avg quality:
0.7000

High-Q hyps:
3

Total hyps:
7

Quality per $: 77777.8

🤖 clinical trialist

Est. cost:
$0.694

Avg quality:
0.6550

High-Q hyps:
42

Total hyps:
67

Quality per $: 0.9

🤖 epidemiologist

Est. cost:
$0.121

Avg quality:
0.6176

High-Q hyps:
11

Total hyps:
15

Quality per $: 5.1

🤖 computational biologist

Est. cost:
$0.003

Avg quality:
0.4000

High-Q hyps:
12

Total hyps:
22

Quality per $: 132.3

Hypothesis-Debate Links

How debates connect to hypotheses — tracking score evolution through the debate process

290

Hypothesis-Debate Links

196

Unique Hypotheses Debated

0.644

Avg Post-Debate Score

Hypothesis	Before	After	Change
Stathmin-2 Splice Switching to Prevent Axonal Dege	0.900	7.200	+6.3000
Low Complexity Domain Cross-Linking Inhibition	0.473	0.473	0.0000
Orexin-Microglia Modulation Therapy	0.570	0.570	0.0000
Transcriptional Autophagy-Lysosome Coupling	0.756	0.756	0.0000
Autophagosome Maturation Checkpoint Control	0.694	0.694	0.0000
Lysosomal Enzyme Trafficking Correction	0.672	0.672	0.0000
Lysosomal Calcium Channel Modulation Therapy	0.703	0.703	0.0000
Lysosomal Membrane Repair Enhancement	0.604	0.604	0.0000
Lysosomal Positioning Dynamics Modulation	0.556	0.556	0.0000
Mitochondrial-Lysosomal Contact Site Engineering	0.619	0.619	0.0000
Adenosine-Astrocyte Metabolic Reset	0.710	0.710	0.0000
Circadian Glymphatic Rescue Therapy (Melatonin-foc	0.708	0.708	0.0000
Circadian Clock-Autophagy Synchronization	0.662	0.662	0.0000
Noradrenergic-Tau Propagation Blockade	0.608	0.608	0.0000
Glycine-Rich Domain Competitive Inhibition	0.573	0.573	0.0000
Sleep Spindle-Synaptic Plasticity Enhancement	0.545	0.545	0.0000
Hypocretin-Neurogenesis Coupling Therapy	0.445	0.445	0.0000
Circadian Glymphatic Entrainment via Targeted Orex	0.812	0.812	0.0000
Endothelial Glycocalyx Regeneration via Syndecan-1	0.710	0.710	0.0000
Serine/Arginine-Rich Protein Kinase Modulation	0.545	0.545	0.0000

Scientific Tool Usage

Which tools are used most, their reliability, and performance

Tool	Calls	Success Rate	Avg Latency	Analyses
PubMed Search	25,735	100%	0.6s	7
Semantic Scholar Search	8,695	100%	1.0s	3
OpenAlex Works Search	7,080	100%	0.6s	3
Clinical Trials Search	4,782	100%	1.1s	3
PubMed Abstract	2,469	100%	1.3s	6
Gene Info	2,332	100%	1.1s	3
Research Topic	1,448	98%	3.8s	1
GTEx Tissue Expression	1,405	99%	0.3s	2
Reactome Pathways	927	99%	0.7s	5
Paper Figures	768	98%	16.0s	0
STRING Protein Interactions	619	97%	1.2s	4
UniProt Protein Info	511	98%	0.7s	3
Allen Brain Expression	457	98%	0.3s	1
Open Targets Associations	417	98%	1.5s	3
Paper Corpus Search	411	99%	5.0s	5
ClinVar Variants	376	99%	1.0s	5
unknown	321	100%	0.5s	0
Allen Cell Types	256	98%	1.5s	1
Paper Review Workflow	222	100%	42.7s	0
DisGeNET Gene-Disease Associations	217	99%	1.8s	3
NIH RePORTER Projects	184	100%	0.4s	0
Enrichr Pathway Analysis	182	96%	1.6s	2
DisGeNET Disease-Gene Associations	179	97%	2.0s	0
AlphaFold Structure	155	94%	1.2s	0
GWAS Genetic Associations	142	96%	2.6s	2
Human Protein Atlas	142	99%	2.1s	0
STRING Enrichment	132	92%	2.0s	0
unknown	129	99%	0.1s	0
ChEMBL Drug Targets	107	93%	5.2s	0
KEGG Pathways	86	97%	5.4s	2
PubChem Compound	74	66%	0.3s	0
MSigDB Gene Sets	69	74%	1.1s	0
Paper Corpus Ingest	69	68%	0.0s	0
unknown	68	100%	0.9s	5
Expression Atlas Differential	63	86%	2.8s	0
BrainSpan Expression	59	88%	0.0s	0
MGI Mouse Models	46	85%	0.1s	0
InterPro Protein Domains	41	88%	1.3s	0
Disease Info	40	88%	0.8s	0
DGIdb Drug-Gene Interactions	36	94%	0.1s	0
gnomAD Gene Variants	33	91%	0.8s	0
HPO Phenotype Associations	30	100%	1.0s	0
Paper Corpus Session	28	100%	4.4s	0
MethBase Disease Methylation	27	85%	1.4s	0
EBI Protein Variants	24	79%	1.6s	0
Ensembl Gene Info	23	91%	2.8s	0
QuickGO Gene Ontology	21	90%	1.2s	0
Pathway Commons Search	20	75%	0.2s	0
Monarch Disease-Gene Associations	20	75%	0.5s	0
OMIM Gene Phenotypes	20	90%	0.5s	0
DrugBank Drug Info	19	89%	0.5s	0
HPO Term Search	17	100%	0.3s	0
IntAct Molecular Interactions	17	88%	2.2s	0
CellxGene Gene Expression	17	88%	2.1s	0
Open Targets Search	17	100%	0.3s	0
COSMIC Gene Mutations	16	88%	0.4s	0
DisGeNET Disease Similarity	15	73%	0.2s	0
PharmGKB Pharmacogenomics	15	87%	0.3s	0
STITCH Chemical Interactions	15	87%	1.2s	0
PubMed Evidence Pipeline	14	100%	46.2s	0
JASPAR TF Binding Sites	14	79%	2.3s	0
ClinGen Gene-Disease Validity	14	86%	1.3s	0
Europe PMC Search	14	100%	1.0s	0
unknown	14	100%	0.3s	5
BioGRID Interactions	13	85%	0.0s	0
GEO Dataset Search	13	100%	0.6s	0
unknown	12	100%	0.0s	0
Gene Ontology Annotations	12	100%	1.2s	0
PanglaoDB Cell Markers	12	100%	0.6s	0
unknown	12	100%	0.0s	0
unknown	12	100%	0.0s	0
unknown	12	100%	0.0s	0
unknown	12	100%	0.0s	0
Bgee Gene Expression	11	82%	2.2s	0
Open Targets RNA Expression	11	73%	0.1s	0
Agora AMP-AD Target Scoring	10	70%	0.1s	0
unknown	9	100%	1.4s	4
Ensembl Regulatory Features	9	67%	1.0s	0
HGNC Gene Nomenclature	9	78%	0.2s	0
WikiPathways Gene Pathways	9	78%	0.3s	0
Pharos Target Development	9	78%	0.1s	0
PDB Protein Structures	9	78%	0.3s	0
Open Targets Genetics L2G	9	67%	0.1s	0
ENCODE Regulatory Search	8	75%	0.0s	0
NCBI Gene Summary	8	75%	0.3s	0
UniProt PTM Features	8	75%	0.6s	0
OmniPath Signaling	8	75%	0.6s	0
IMPC Mouse Phenotypes	8	75%	0.3s	0
ProteomicsDB Protein Expression	8	38%	0.2s	0
Open Targets Tractability	8	75%	0.2s	0
Europe PMC Citations	7	43%	0.1s	0
JensenLab DISEASES Text Mining	7	71%	0.0s	0
Harmonizome Gene Sets	7	57%	1.1s	0
GWAS Catalog Variant Associations	7	43%	6.2s	0
GTEx Brain eQTLs	7	71%	0.5s	0
EBI Complex Portal	7	71%	0.3s	0
OpenGWAS PheWAS Associations	7	43%	0.1s	0
Open Targets Drugs	7	71%	0.2s	0
Ensembl VEP Variant Annotation	7	43%	0.2s	0
Open Targets Mouse Phenotypes	7	71%	0.1s	0
BindingDB Binding Affinity	6	100%	0.8s	0
MethBase Age Correlation	6	100%	0.8s	0
Allen Aging Atlas Expression	6	100%	0.1s	0
GTEx Brain sQTLs	6	67%	0.4s	0
EBI OLS Term Lookup	6	100%	1.0s	0
BioStudies Dataset Search	6	100%	0.9s	0
ChEMBL Compound Search	5	100%	6.1s	0
unknown	5	100%	0.3s	0
AGR Gene Orthologs	4	100%	0.5s	0
MethBase Gene Methylation	4	100%	0.9s	0
MethBase Tissue Methylation	3	100%	0.6s	0
CrossRef Paper Metadata	3	100%	0.2s	0
unknown	3	100%	0.0s	0
MethBase CpG Islands	2	100%	0.0s	0
UniChem Compound Cross-References	2	100%	15.5s	0
ABC Atlas Spatial Expression	2	100%	0.7s	0
unknown	2	100%	1.1s	0
Retraction Check	2	100%	3.3s	0
unknown	2	100%	4.7s	2
unknown	2	100%	0.7s	0
MethBase Developmental Methylation	2	100%	0.9s	0
Genomics England PanelApp	1	100%	0.9s	0
unknown	1	100%	0.3s	0
CrossRef Preprint Search	1	100%	0.3s	0
CIViC Gene Variants	1	100%	0.1s	0
unknown	1	100%	2.1s	0
unknown	1	100%	0.6s	0
PubTator3 Gene/Disease Annotations	1	100%	3.5s	0
OmniPath PTM Interactions	1	100%	1.0s	0
NCBI SRA Dataset Search	1	100%	0.5s	0
NCBI dbSNP Variant Lookup	1	100%	0.5s	0
unknown	1	100%	0.0s	0
MethBase Tissue Comparison	1	100%	0.0s	0
MethBase Differential Analysis	1	100%	0.0s	0
MethBase Conservation	1	100%	0.0s	0
LIPID MAPS Lipid Search	1	100%	1.7s	0
KEGG Disease Gene Associations	1	100%	1.4s	0
openFDA Adverse Events	1	100%	0.1s	0
unknown	1	100%	0.0s	0
unknown	1	100%	0.0s	0

Top Debates by Quality

Highest-quality debates — the gold standard for agent collaboration

Analysis	Quality	Generated	Surviving	Date
Blood-brain barrier permeability changes as e	1.000	3	3	2026-04-26
What blood-brain barrier permeability changes	1.000	7	5	2026-04-26
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How does the intron-retained RNA isoform mech	1.000	7	5	2026-04-26
Can CSF p-tau217 normalization serve as a rel	1.000	7	2	2026-04-26
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Comparative epigenetic signatures: DNA methyl	1.000	7	4	2026-04-20