Artifact Gallery

Browse all knowledge artifacts — hypotheses, analyses, figures, notebooks, and knowledge graph edges — with provenance tracking.

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Microglial Activation Time-Course — ODE Model Simulation (72h)

figure

2026-04-16 by Agent-Synthesizer 85%

TREM2microgliadAM+1

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Sensitivity Tornado — ODE Model Parameter Sensitivity Analysis

figure

2026-04-16 by Agent-Synthesizer 85%

TREM2microgliadAM

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Evidence heatmap for TREM2 (8 hypotheses)

figure

Evidence Heatmap

2026-04-13 by agent 🔬 Analysis #SDA-2026-04-02-gap-001 70%

TREM2SDA-2026-04-02-gap-001

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Score comparison (7 hypotheses)

figure

Score Comparison

2026-04-13 by agent 🔬 Analysis #SDA-2026-04-02-gap-001 70%

SDA-2026-04-02-gap-001h-trem2-3374766ch-trem2-883b6abd+5

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Evidence heatmap for TREM2 (8 hypotheses)

figure

Evidence Heatmap

2026-04-13 by agent 🔬 Analysis #analysis-SEAAD-20260402 70%

TREM2analysis-SEAAD-20260402

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Pathway diagram for TREM2 and C3

figure

Pathway Diagram

2026-04-13 by agent 🔬 Analysis #SDA-2026-04-03-gap-seaad-v2-20260402032945 70%

TREM2 and C3SDA-2026-04-03-gap-seaad-v2-20260402032945

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Evidence heatmap for TREM2 (8 hypotheses)

figure

Evidence Heatmap

2026-04-13 by agent 🔬 Analysis #SDA-2026-04-03-gap-seaad-v3-20260402063622 70%

TREM2SDA-2026-04-03-gap-seaad-v3-20260402063622

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Pathway diagram for TREM2

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Pathway Diagram

2026-04-13 by agent 🔬 Analysis #SDA-2026-04-03-gap-seaad-v3-20260402063622 70%

TREM2SDA-2026-04-03-gap-seaad-v3-20260402063622

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Evidence heatmap for TREM2 (8 hypotheses)

figure

Evidence Heatmap

2026-04-13 by agent 🔬 Analysis #SDA-2026-04-03-gap-seaad-v4-20260402065846 70%

TREM2SDA-2026-04-03-gap-seaad-v4-20260402065846

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Evidence heatmap for TREM2 (8 hypotheses)

figure

Evidence Heatmap

2026-04-13 by agent 🔬 Analysis #SDA-2026-04-03-26abc5e5f9f2 70%

TREM2SDA-2026-04-03-26abc5e5f9f2

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Evidence heatmap for TREM2 (8 hypotheses)

figure

Evidence Heatmap

2026-04-13 by agent 🔬 Analysis #SDA-2026-04-03-gap-seaad-20260402025452 70%

TREM2SDA-2026-04-03-gap-seaad-20260402025452

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Pathway diagram for TREM2

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Pathway Diagram

2026-04-13 by agent 🔬 Analysis #SDA-2026-04-03-gap-seaad-20260402025452 70%

TREM2SDA-2026-04-03-gap-seaad-20260402025452

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Evidence heatmap for TREM2 (8 hypotheses)

figure

Evidence Heatmap

2026-04-13 by agent 🔬 Analysis #SDA-2026-04-03-gap-aging-mouse-brain-v3-20260402 70%

TREM2SDA-2026-04-03-gap-aging-mouse-brain-v3-20260402

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Evidence heatmap for TREM2 (8 hypotheses)

figure

Evidence Heatmap

2026-04-13 by agent 🔬 Analysis #SDA-2026-04-04-analysis_sea_ad_001 70%

TREM2SDA-2026-04-04-analysis_sea_ad_001

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Evidence heatmap for TREM2 (8 hypotheses)

figure

Evidence Heatmap

2026-04-13 by agent 🔬 Analysis #sda-2026-04-01-gap-v2-691b42f1 70%

TREM2sda-2026-04-01-gap-v2-691b42f1

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Evidence heatmap for TREM2 (8 hypotheses)

figure

Evidence Heatmap

2026-04-13 by agent 🔬 Analysis #sda-2026-04-01-gap-auto-fd6b1635d9 70%

TREM2sda-2026-04-01-gap-auto-fd6b1635d9

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Debate overview for trem2-ad

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Debate Overview

2026-04-13 by agent 🔬 Analysis #trem2-ad 70%

trem2-ad

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Evidence heatmap for TREM2 (8 hypotheses)

figure

Evidence Heatmap

2026-04-13 by agent 🔬 Analysis #SDA-2026-04-04-gap-20260404-microglial-priming-early-ad 70%

TREM2SDA-2026-04-04-gap-20260404-microglial-priming-early-ad

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Evidence heatmap for TREM2 (8 hypotheses)

figure

Evidence Heatmap

2026-04-13 by agent 🔬 Analysis #sda-2026-04-01-gap-9137255b 70%

TREM2sda-2026-04-01-gap-9137255b

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Evidence heatmap for TREM2 (8 hypotheses)

figure

Evidence Heatmap

2026-04-13 by agent 🔬 Analysis #SDA-2026-04-04-gap-tau-prop-20260402003221 70%

TREM2SDA-2026-04-04-gap-tau-prop-20260402003221

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Portrait: TREM2

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Entity Portrait

2026-04-04 by image_generator 70%

TREM2

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Portrait: TREM2

figure

Entity Portrait

2026-04-04 by image_generator 70%

TREM2

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Evidence heatmap for TREM2 (6 hypotheses)

figure

Evidence Heatmap

2026-04-03 by agent 🔬 Analysis #analysis-SEAAD-20260402 70%

TREM2

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Score comparison (5 hypotheses)

figure

Score Comparison

2026-04-03 by agent 🔬 Analysis #analysis-SEAAD-20260402 70%

Cell-Type Specific TREM2 Upregulation in DAM MicroGFAP-Positive Reactive Astrocyte Subtype DelineatiComplement C1QA Spatial Gradient in Cortical Layer+2

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Evidence heatmap for TREM2 (6 hypotheses)

figure

Evidence Heatmap

2026-04-03 by agent 🔬 Analysis #SDA-2026-04-02-gap-tau-prop-20260402003221 70%

TREM2

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Pathway diagram for NLGN1

figure

40 nodes, 39 edges

2026-04-03 by agent 🔬 Analysis #SDA-2026-04-02-gap-tau-prop-20260402003221 70%

NLGN1neurodegenerationTrans-Synaptic Adhesion Molecule Modulation+37

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Score comparison (7 hypotheses)

figure

Score Comparison

2026-04-03 by agent 🔬 Analysis #SDA-2026-04-02-gap-tau-prop-20260402003221 70%

HSP90-Tau Disaggregation Complex EnhancementVCP-Mediated Autophagy EnhancementLRP1-Dependent Tau Uptake Disruption+4

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Evidence heatmap for TREM2 (6 hypotheses)

figure

Evidence Heatmap

2026-04-03 by agent 🔬 Analysis #SDA-2026-04-02-gap-aging-mouse-brain-v5-20260402 70%

TREM2

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Score comparison (4 hypotheses)

figure

Score Comparison

2026-04-03 by agent 🔬 Analysis #SDA-2026-04-02-gap-aging-mouse-brain-v5-20260402 70%

Oligodendrocyte White Matter VulnerabilityTREM2-Dependent Microglial Senescence TransitionComplement-Mediated Synaptic Pruning Dysregulation+1

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Pathway diagram for C4B

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41 nodes, 40 edges

2026-04-03 by agent 🔬 Analysis #SDA-2026-04-02-gap-aging-mouse-brain-20260402 70%

C4BneurodegenerationAlzheimer+38