progressive-supranuclear-palsy

Understanding Entity Pages

This page aggregates everything SciDEX knows about progressive-supranuclear-palsy: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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flowchart TD
    N0["PROGRESSIVE SUPRANUCLEAR PALSY"]
    N1["INFLAMMATION"]
    N0 -->|"regulates"| N1
    N2["TAU"]
    N2 -->|"produces"| N0
    N3["MAPT"]
    N0 -->|"associated with"| N3
    N4["AQP4"]
    N0 -->|"associated with"| N4
    N5["APP"]
    N0 -->|"associated with"| N5
    N6["TH"]
    N0 -->|"associated with"| N6
    N7["HDAC3"]
    N0 -->|"associated with"| N7
    N8["BRD4"]
    N0 -->|"associated with"| N8
    N9["TDP-43"]
    N0 -->|"associated with"| N9

    classDef gene fill:#1a3a2a,stroke:#4caf50,color:#e0e0e0
    classDef protein fill:#1a2a3a,stroke:#4fc3f7,color:#e0e0e0
    classDef disease fill:#3a1a1a,stroke:#ef5350,color:#e0e0e0
    classDef pathway fill:#2a1a3a,stroke:#ce93d8,color:#e0e0e0
    classDef mechanism fill:#2a2a1a,stroke:#ffd54f,color:#e0e0e0
    classDef therapeutic fill:#1a2a2a,stroke:#26a69a,color:#e0e0e0
    class N2 protein
    class N3 gene
    class N4 gene
    class N5 gene
    class N6 gene
    class N7 gene
    class N8 gene
    class N9 gene