Scientific World Model

The world's most comprehensive mechanistic knowledge base for neurodegenerative diseases.

17,471 pages — genes, proteins, mechanisms, therapeutics, and more

What is the Scientific World Model?

Our AI agents have synthesized 17,000+ wiki-style pages covering every major entity, mechanism, and therapeutic avenue in neurodegeneration research. Each page is automatically generated and continuously updated from the latest scientific literature, connecting genes like APOE and MAPT to pathways, proteins, and disease mechanisms.

This forms a living knowledge graph that powers our hypothesis generation, therapeutic target identification, and research gap analysis. Browse by entity type below or search for any gene, protein, mechanism, or drug.

All (17,471)🧬 gene (3,869)🔬 cell (3,397)🔬 protein (3,107)⚙️ mechanism (1,789)💊 therapeutic (1,028)🏢 company (643)🏥 disease (496)🧪 clinical (392)🏛️ institution (308)👤 researcher (214)💡 idea (200)↪️ redirect (185)📊 biomarker (182)🧫 experiment (161) general (151)🔧 technology (151) ai_tool (141) entity (113)
Showing 1–50 of 106 pages matching "AD"

🔬 Locus Coeruleus Noradrenergic NeuronsKG

cell · 2,822 words · 6 hyp11 ana1 exp

🔬 Adenosine A2B Receptor NeuronsKG

cell · 2,548 words · 12 hyp16 ana1 exp

🔬 HPA Axis Neurons in NeurodegenerationKG

cell · 2,540 words · 281 hyp44 ana56 exp

🔬 Noradrenergic System in NeurodegenerationKG

cell · 2,520 words · 285 hyp41 ana57 exp

🔬 Locus Coeruleus Noradrenergic Projection NeuronsKG

cell · 2,344 words · 6 hyp12 ana3 exp

🔬 Adenosine A2B Receptor NeuronsKG

cell · 2,236 words · 10 hyp15 ana1 exp

🔬 Locus Coeruleus (LC) Noradrenergic NeuronsKG

cell · 2,109 words · 6 hyp12 ana1 exp

🔬 Noradrenergic Locus Coeruleus in Major Depressive DisorderKG

cell · 1,919 words · 10 hyp9 ana5 exp

🔬 Adrenal Chromaffin Cells in NeurodegenerationKG

cell · 1,711 words · 284 hyp55 ana58 exp

🔬 Cortical Layer 5 Pyramidal Neurons in Alzheimer's DiseaseKG

cell · 1,697 words · 68 hyp37 ana61 exp

🔬 Circadian Rhythm NeuronsKG

cell · 1,687 words · 52 hyp43 ana9 exp

🔬 Adenosine A2A Receptor NeuronsKG

cell · 1,626 words · 10 hyp15 ana1 exp

🔬 Beta-2 Adrenergic Receptor NeuronsKG

cell · 1,605 words · 14 hyp17 ana4 exp

🔬 A2 Noradrenergic NeuronsKG

cell · 1,410 words · 6 hyp13 ana2 exp

🔬 Alpha-1 Adrenergic Receptor Neurons in NeurodegenerationKG

cell · 1,406 words · 280 hyp51 ana54 exp

🔬 Alpha-2 Adrenergic Receptor NeuronsKG

cell · 1,385 words · 10 hyp16 ana4 exp

🔬 Noradrenergic Neurons (Locus Coeruleus)KG

cell · 1,375 words · 20 hyp12 ana1 exp

🔬 Adiponectin-Responsive NeuronsKG

cell · 1,361 words · 5 hyp12 ana4 exp

🔬 Locus Coeruleus Alpha Adrenergic NeuronsKG

cell · 1,344 words · 6 hyp13 ana4 exp

🔬 Cortical Head Direction CellsKG

cell · 1,343 words · 6 hyp8 ana1 exp

🔬 Radial Glia in NeurodegenerationKG

cell · 1,314 words · 285 hyp54 ana59 exp

🔬 Locus Coeruleus Noradrenergic SystemKG

cell · 1,307 words · 12 hyp17 ana1 exp

🔬 Vascular Smooth Muscle Cells in CADASILKG

cell · 1,304 words · 17 hyp7 ana1 exp

🔬 Adrenal Chromaffin CellsKG

cell · 1,273 words · 16 hyp21 ana1 exp

🔬 Suprachiasmatic Nucleus Neurons in Circadian DisordersKG

cell · 1,211 words · 20 hyp18 ana9 exp

🔬 Radial GliaKG

cell · 1,199 words · 184 hyp56 ana9 exp

🔬 Beta-1 Adrenergic Receptor NeuronsKG

cell · 1,190 words · 9 hyp14 ana1 exp

🔬 Locus Coeruleus Alpha-2 Adrenergic NeuronsKG

cell · 1,169 words · 7 hyp13 ana4 exp

🔬 Locus Coeruleus Norepinephrine in ADKG

cell · 1,156 words · 41 hyp9 ana5 exp

🔬 Gonadotropin-Releasing Hormone (GnRH) NeuronsKG

cell · 1,136 words · 5 hyp11 ana1 exp

🔬 CADASIL Vascular CellsKG

cell · 1,132 words · 7 hyp7 ana1 exp

🔬 Retinal Ganglion Cells in Alzheimer's DiseaseKG

cell · 1,078 words · 46 hyp31 ana51 exp

🔬 Cholinergic Neurons in Adult Polyglucosan Body DiseaseKG

cell · 1,065 words · 9 hyp24 ana1 exp

🔬 Beta-3 Adrenergic Receptor NeuronsKG

cell · 1,052 words · 9 hyp14 ana1 exp

🔬 Locus Coeruleus Noradrenaline NeuronsKG

cell · 1,052 words · 5 hyp11 ana1 exp

🔬 Hypothalamic-Pituitary-Adrenal Axis Neurons in Cushing DiseaseKG

cell · 999 words · 11 hyp27 ana

🔬 Gonadal Axis Neurons in Gonadotropin-Secreting AdenomaKG

cell · 999 words · 9 hyp15 ana2 exp

🔬 Locus Coeruleus Alpha-2 Adrenergic NeuronsKG

cell · 991 words · 6 hyp13 ana1 exp

🔬 Hypothalamic Neurons in Growth Hormone ExcessKG

cell · 971 words · 7 hyp12 ana

🔬 Gonadotropin-Releasing Hormone (GnRH) NeuronsKG

cell · 970 words · 5 hyp12 ana1 exp

🔬 Hypothalamic POMC Neurons in Prader-Willi SyndromeKG

cell · 949 words · 6 hyp12 ana1 exp

🔬 Disease-Associated Microglia in Alzheimer's DiseaseKG

cell · 945 words · 86 hyp38 ana54 exp

🔬 Adenosine Receptor (A1/A2A) NeuronsKG

cell · 945 words · 10 hyp15 ana

🔬 Interanterodorsal Thalamic Nucleus (IAD) NeuronsKG

cell · 942 words · 7 hyp12 ana1 exp

🔬 Hypothalamic POMC Neurons in Prader-Willi SyndromeKG

cell · 940 words · 6 hyp12 ana1 exp

🔬 Locus Coeruleus Noradrenergic Neurons in Alzheimer's DiseaseKG

cell · 931 words · 69 hyp31 ana51 exp

🔬 Pinealocytes in Circadian Rhythm DisordersKG

cell · 928 words · 18 hyp14 ana1 exp

🔬 Circadian Clock NeuronsKG

cell · 925 words · 57 hyp43 ana9 exp

🔬 Radial Glia NeuronsKG

cell · 890 words · 9 hyp12 ana2 exp

🔬 Vascular Smooth Muscle Cells in CADASILKG

cell · 885 words · 15 hyp10 ana1 exp

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