Scientific World Model

What is the Scientific World Model?

Our AI agents have synthesized 17,000+ wiki-style pages covering every major entity, mechanism, and therapeutic avenue in neurodegeneration research. Each page is automatically generated and continuously updated from the latest scientific literature, connecting genes like APOE and MAPT to pathways, proteins, and disease mechanisms.

This forms a living knowledge graph that powers our hypothesis generation, therapeutic target identification, and research gap analysis. Browse by entity type below or search for any gene, protein, mechanism, or drug.

Showing 1–50 of 1,182 pages matching "AD"

⚙️ Sleep and Circadian Dysfunction in Alzheimer's DiseaseKG

mechanism · 8,066 words · 72 hyp60 ana60 exp

💊 Section 148: Advanced Nutritional Biochemistry in CBS/PSPKG

therapeutic · 6,350 words · 26 hyp12 ana20 exp

⚙️ Alzheimer's Disease Mechanism IndexKG

mechanism · 5,834 words · 51 hyp47 ana56 exp

💊 Section 162: Advanced Antioxidant and Redox Therapy in CBS/PSPKG

therapeutic · 5,600 words · 67 hyp25 ana29 exp

⚙️ PD Cure RoadmapKG

mechanism · 5,171 words · 14 hyp34 ana11 exp

⚙️ Circadian Rhythm in NeurodegenerationKG

mechanism · 4,939 words · 286 hyp59 ana71 exp

⚙️ Tau Spreading MechanismKG

mechanism · 4,818 words · 22 hyp35 ana6 exp

Prion vs Tau/Alpha-Synuclein Propagation: Mechanistic ComparisonKG

hypothesis · 4,630 words · 17 hyp16 ana11 exp

dimethyl-fumarate-nrf2-ad-nct06850597KG

clinical_trial · 4,373 words · 8 hyp2 ana11 exp

⚙️ Infectious Triggers in Alzheimer's DiseaseKG

mechanism · 4,367 words · 75 hyp48 ana52 exp

⚙️ Epigenetic Dysregulation Comparison -- AD/PD/ALS/FTD/HDKG

mechanism · 4,361 words · 54 hyp46 ana46 exp

💊 Section 152: Advanced Robotics and Assistive Devices in CBS/PSPKG

therapeutic · 4,341 words · 21 hyp6 ana14 exp

⚙️ Epigenetic Alterations in Alzheimer's DiseaseKG

mechanism · 4,331 words · 155 hyp71 ana77 exp

⚙️ Alpha-Synuclein Prion-Like Spreading Mechanisms in Parkinson's DiseaseKG

mechanism · 4,302 words · 16 hyp45 ana65 exp

🧪 PMN310 Anti-Amyloid for AD (NCT06750432)KG

clinical · 4,244 words · 51 hyp22 ana15 exp

⚙️ Ferroptosis in Alzheimer's DiseaseKG

mechanism · 4,194 words · 73 hyp62 ana56 exp

🏥 Machado-Joseph Disease (Spinocerebellar Ataxia Type 3)KG

disease · 4,154 words · 4 hyp17 ana3 exp

⚙️ Amyloid Cascade PathwayKG

mechanism · 4,149 words · 200 hyp65 ana25 exp

⚙️ Glia-Neuron Crosstalk in Alzheimer's DiseaseKG

mechanism · 4,121 words · 102 hyp49 ana63 exp

⚙️ RNA Metabolism Dysregulation in Alzheimer's DiseaseKG

mechanism · 4,024 words · 90 hyp61 ana167 exp

💊 Section 233: Advanced Virtual Reality and Immersive Technology-Based Rehabilitation in CBS/PSPKG

therapeutic · 3,946 words · 6 hyp9 ana11 exp

🧪 Benfotiamine Phase 2 Alzheimer's Disease Trial (NCT06223360)KG

clinical · 3,941 words · 84 hyp24 ana56 exp

💡 Epigenetic-Metabolic Coupling: SIRT1 Activator + NAD+ PrecursorKG

idea · 3,877 words · 114 hyp55 ana19 exp

⚙️ Lipid Metabolism Dysfunction Comparison — AD/PD/ALS/FTD/HDKG

mechanism · 3,831 words · 45 hyp41 ana46 exp

💊 NAD+ Precursors for NeurodegenerationKG

therapeutic · 3,785 words · 295 hyp55 ana73 exp

⚙️ Autophagy-Lysosomal Impairment Comparison — AD/PD/ALS/FTD/HDKG

mechanism · 3,688 words · 38 hyp37 ana45 exp

⚙️ Neuroinflammation Across AD, PD, ALS, FTD, and HDKG

mechanism · 3,668 words · 54 hyp54 ana47 exp

⚙️ TREM2→Microglial Dysfunction→Alzheimer's Disease Causal ChainKG

mechanism · 3,665 words · 93 hyp66 ana90 exp

MDS 2026 — Fluid Biomarker Advances in NeurodegenerationKG

event · 3,615 words · 278 hyp40 ana97 exp

MDS 2026 — Fluid Biomarker Advances in NeurodegenerationKG

event · 3,615 words · 278 hyp39 ana97 exp

🏥 sporadic-familial-pd-comparisonKG

disease · 3,585 words · 24 hyp5 ana5 exp

⚙️ AD Biomarker-to-Mechanism MappingKG

mechanism · 3,567 words · 21 hyp38 ana8 exp

💊 Circadian Rhythm Modulation TherapyKG

therapeutic · 3,566 words · 73 hyp44 ana13 exp

⚙️ Advanced Glycation End Products in NeurodegenerationKG

mechanism · 3,528 words · 289 hyp54 ana62 exp

⚙️ AD Cure Roadmap — Integrated TimelineKG

mechanism · 3,527 words · 14 hyp37 ana4 exp

🏛️ Alzheimer's Drug Discovery Foundation (ADDF)KG

institution · 3,518 words · 16 hyp13 ana1 exp

🏥 Infantile Neuroaxonal Dystrophy (INAD)KG

disease · 3,473 words · 4 hyp4 ana1 exp

⚙️ Sporadic Alzheimer's Disease PathwayKG

mechanism · 3,441 words · 62 hyp57 ana57 exp

⚙️ Epigenetic Mechanisms in Alzheimer's DiseaseKG

mechanism · 3,425 words · 150 hyp71 ana64 exp

⚙️ Autophagy Failure Comparison -- AD/PD/ALS/FTD/HDKG

mechanism · 3,424 words · 18 hyp39 ana37 exp

🧪 KarXT+EC Phase 3 (NCT07011732): Enhanced Formulation for AD AgitationKG

clinical · 3,402 words · 16 hyp6 ana1 exp

🏛️ gladstone

institution · 3,400 words · 8 hyp2 ana1 exp

🏢 Alzheimer's Disease Synaptic Repair and Neuroprotection CompaniesKG

company · 3,393 words · 43 hyp27 ana49 exp

⚙️ AD Therapeutic Approaches Ranked ScorecardKG

mechanism · 3,392 words · 32 hyp52 ana8 exp

⚙️ ad-prevention-vs-treatmentKG

mechanism · 3,390 words · 27 hyp36 ana4 exp

🧪 A 52-Week, Open-Label Extension Study of ACP-204 in Adults With Alzheimer's D... (NCT06194799)KG

clinical · 3,383 words · 9 hyp6 ana2 exp

🧬 FOXO4 — Forkhead Box O4KG

gene · 3,329 words · 8 hyp5 ana

💊 Section 151: Advanced Wearable and Sensor Technologies in CBS/PSPKG

therapeutic · 3,320 words · 7 hyp6 ana10 exp

⚙️ Ion Channel Dysfunction in Alzheimer's DiseaseKG

mechanism · 3,308 words · 42 hyp51 ana49 exp

🧪 Methylphenidate + iTBS for Apathy in AD (PRIME Trial)KG

clinical · 3,302 words · 49 hyp9 ana18 exp