Scientific World Model

The world's most comprehensive mechanistic knowledge base for neurodegenerative diseases.

17,491 pages — genes, proteins, mechanisms, therapeutics, and more

What is the Scientific World Model?

Our AI agents have synthesized 17,000+ wiki-style pages covering every major entity, mechanism, and therapeutic avenue in neurodegeneration research. Each page is automatically generated and continuously updated from the latest scientific literature, connecting genes like APOE and MAPT to pathways, proteins, and disease mechanisms.

This forms a living knowledge graph that powers our hypothesis generation, therapeutic target identification, and research gap analysis. Browse by entity type below or search for any gene, protein, mechanism, or drug.

All (17,491)🧬 gene (3,869)🔬 cell (3,397)🔬 protein (3,107)⚙️ mechanism (1,789)💊 therapeutic (1,028)🏢 company (643)🏥 disease (496)🧪 clinical (392)🏛️ institution (308)👤 researcher (214)💡 idea (200)↪️ redirect (185)📊 biomarker (182)🧫 experiment (161) general (151)🔧 technology (151) ai_tool (141) entity (113)
Showing 1–41 of 41 pages matching "alzheimers-disease"

🏥 Alzheimer's DiseaseKG

disease · 5,265 words · 284 hyp53 ana285 exp

💊 Nanomedicine Approaches to Alzheimer's DiseaseKG

therapeutic · 3,864 words · 48 hyp31 ana54 exp

Choroid-Plexus-in-Alzheimers-DiseaseKG

cell_type · 3,303 words · 210 hyp22 ana21 exp

Cerebellar Granule Cells In Alzheimers DiseaseKG

cell_type · 3,049 words · 16 hyp25 ana2 exp

⚙️ Monoclonal Antibody Therapy in Alzheimer's DiseaseKG

mechanism · 3,043 words · 88 hyp62 ana54 exp

⚙️ [AD](/diseases/alzheimers-disease) Failed Approaches AnalysisKG

mechanism · 3,014 words · 20 hyp59 ana4 exp

⚙️ Tau Pathology Alters Oligodendrocyte Gene Methylation in [Alzheimer's Disease](/diseases/alzheimers-disease)KG

mechanism · 3,013 words · 67 hyp53 ana48 exp

⚙️ Nanomedicine for Alzheimer's DiseaseKG

mechanism · 2,857 words · 40 hyp49 ana54 exp

🔬 Tuberomammillary Nucleus in Alzheimer's DiseaseKG

cell · 2,796 words · 34 hyp24 ana49 exp

APOE contributes to Alzheimer's disease by regulating both beta-amyloid depositionKG

hypothesis · 2,704 words · 60 hyp10 ana48 exp

alzheimers-diseaseKG

clinical_trial · 2,667 words · 21 hyp21 ana9 exp

⚙️ Necroptosis in Alzheimer's DiseaseKG

mechanism · 2,534 words · 34 hyp51 ana52 exp

Alzheimer's disease pathology originates in the hippocampus and subsequently spreadsKG

hypothesis · 2,427 words · 25 hyp20 ana47 exp

⚙️ Alzheimer's Disease Biomarker Temporal Sequence HypothesisKG

mechanism · 2,230 words · 34 hyp49 ana51 exp

⚙️ RNA Metabolism in Alzheimer's DiseaseKG

mechanism · 2,071 words · 57 hyp64 ana169 exp

🏛️ Alzheimer's Disease Research Centers (ADRC) ProgramKG

institution · 2,070 words · 35 hyp21 ana48 exp

alzheimers-diseaseKG

general · 2,009 words · 19 hyp22 ana1 exp

Claustrum-in-Alzheimers-DiseaseKG

cell_type · 1,970 words · 202 hyp19 ana1 exp

In Alzheimer's disease, biomarker events occur in a specific temporal sequence: amyloid-β abnormalitKG

hypothesis · 1,933 words · 38 hyp22 ana53 exp

Autoimmune Hypothesis in Alzheimer's DiseaseKG

hypothesis · 1,793 words · 96 hyp64 ana54 exp

⚙️ Apoptosis Pathways in Alzheimer's DiseaseKG

mechanism · 1,672 words · 111 hyp71 ana48 exp

🧫 Senolytic Therapy (D+Q) Phase IIa Trial in Early Alzheimer's DiseaseKG

experiment · 1,389 words · 50 hyp41 ana49 exp

🏥 Prodromal Alzheimer's DiseaseKG

disease · 1,308 words · 43 hyp23 ana165 exp

💊 Siponimod for Alzheimer's DiseaseKG

therapeutic · 1,219 words · 32 hyp26 ana48 exp

💊 Alzheimer's Disease TreatmentKG

therapeutic · 1,129 words · 49 hyp33 ana60 exp

🏥 Preclinical Alzheimer's DiseaseKG

disease · 1,079 words · 47 hyp26 ana164 exp

🔬 Cortical Neurons in Alzheimer's DiseaseKG

cell · 1,051 words · 47 hyp37 ana55 exp

🔬 Hippocampal CA2 Neurons in Alzheimer DiseaseKG

cell · 915 words · 9 hyp27 ana1 exp

🔧 BCI for Alzheimer's DiseaseKG

technology · 895 words · 39 hyp20 ana48 exp

🔬 Hippocampal CA2 Neurons in Alzheimer's DiseaseKG

cell · 833 words · 35 hyp33 ana51 exp

🔬 Basal Forebrain Cholinergic Neurons in Alzheimer's DiseaseKG

cell · 738 words · 37 hyp30 ana48 exp

AAN 2026 — Alzheimer's DiseaseKG

event · 738 words · 28 hyp20 ana48 exp

🔬 Prefrontal Cortex Neurons in Alzheimer's DiseaseKG

cell · 665 words · 33 hyp29 ana48 exp

🔬 Hypothalamic Orexin Neurons in Alzheimer's DiseaseKG

cell · 662 words · 37 hyp32 ana48 exp

🔬 Horizontal Cells in Alzheimer's DiseaseKG

cell · 643 words · 32 hyp23 ana48 exp

Subiculum-in-Alzheimers-DiseaseKG

cell_type · 636 words · 4 hyp19 ana1 exp

🧫 Neural Stem Cell Therapy for Alzheimer's DiseaseKG

experiment · 572 words · 52 hyp38 ana49 exp

💊 interleukin-2-alzheimers-diseaseKG

therapeutic · 568 words · 3 hyp18 ana1 exp

🔬 Retinal Ganglion Cells in Alzheimer's DiseaseKG

cell · 564 words · 42 hyp34 ana48 exp

🔬 Retinal Bipolar Cells in Alzheimer's DiseaseKG

cell · 526 words · 34 hyp25 ana48 exp

🔬 Enteric Neurons in Alzheimer's DiseaseKG

cell · 526 words · 37 hyp32 ana48 exp

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