Scientific World Model

The world's most comprehensive mechanistic knowledge base for neurodegenerative diseases.

17,471 pages — genes, proteins, mechanisms, therapeutics, and more

What is the Scientific World Model?

Our AI agents have synthesized 17,000+ wiki-style pages covering every major entity, mechanism, and therapeutic avenue in neurodegeneration research. Each page is automatically generated and continuously updated from the latest scientific literature, connecting genes like APOE and MAPT to pathways, proteins, and disease mechanisms.

This forms a living knowledge graph that powers our hypothesis generation, therapeutic target identification, and research gap analysis. Browse by entity type below or search for any gene, protein, mechanism, or drug.

All (17,471)🧬 gene (3,869)🔬 cell (3,397)🔬 protein (3,107)⚙️ mechanism (1,789)💊 therapeutic (1,028)🏢 company (643)🏥 disease (496)🧪 clinical (392)🏛️ institution (308)👤 researcher (214)💡 idea (200)↪️ redirect (185)📊 biomarker (182)🧫 experiment (161) general (151)🔧 technology (151) ai_tool (141) entity (113)
Showing 1–44 of 44 pages matching "metabolism"

⚙️ Energy Metabolism Dysfunction Comparison Across Neurodegenerative DiseasesKG

mechanism · 4,869 words · 38 hyp41 ana5 exp

⚙️ RNA Metabolism Dysregulation in Alzheimer's DiseaseKG

mechanism · 4,024 words · 90 hyp61 ana167 exp

⚙️ Lipid Metabolism Dysfunction Comparison — AD/PD/ALS/FTD/HDKG

mechanism · 3,831 words · 45 hyp41 ana46 exp

⚙️ Hydrogen Peroxide Metabolism PathwayKG

mechanism · 3,544 words · 24 hyp41 ana13 exp

⚙️ Lipid Metabolism Dysregulation in NeurodegenerationKG

mechanism · 3,499 words · 297 hyp60 ana71 exp

Sphingolipid Metabolism in NeurodegenerationKG

mechanisms · 3,241 words · 290 hyp58 ana65 exp

⚙️ ALS RNA Metabolism and Proteostasis FailureKG

mechanism · 3,179 words · 27 hyp60 ana59 exp

⚙️ Glutathione Metabolism PathwayKG

mechanism · 3,056 words · 48 hyp50 ana3 exp

⚙️ NAD+ Metabolism in NeurodegenerationKG

mechanism · 3,033 words · 294 hyp60 ana75 exp

⚙️ Energy Metabolism in NeurodegenerationKG

mechanism · 3,011 words · 292 hyp58 ana62 exp

⚙️ iron-metabolism-neurodegenerationKG

mechanism · 2,926 words · 320 hyp61 ana56 exp

⚙️ one-carbon-metabolism-neurodegenerationKG

mechanism · 2,848 words · 281 hyp57 ana54 exp

⚙️ Sulfatide Metabolism in NeurodegenerationKG

mechanism · 2,842 words · 283 hyp57 ana65 exp

⚙️ Parkinson's Disease MetabolismKG

mechanism · 2,818 words · 18 hyp47 ana63 exp

⚙️ Serum Amino Acid Biomarkers for Brain HypometabolismKG

mechanism · 2,337 words · 22 hyp41 ana14 exp

⚙️ RNA Metabolism in NeurodegenerationKG

mechanism · 2,301 words · 288 hyp61 ana169 exp

⚙️ Prion Protein Metabolism in NeurodegenerationKG

mechanism · 2,230 words · 284 hyp55 ana55 exp

⚙️ RNA Metabolism in Alzheimer's DiseaseKG

mechanism · 2,071 words · 63 hyp66 ana169 exp

⚙️ NAD+ Metabolism Pathway in NeurodegenerationKG

mechanism · 2,062 words · 295 hyp60 ana72 exp

⚙️ Dopamine Metabolism in PDKG

mechanism · 2,046 words · 118 hyp60 ana4 exp

⚙️ Sphingolipid Metabolism Dysregulation in 4R-TauopathiesKG

mechanism · 1,999 words · 42 hyp41 ana18 exp

⚙️ Sphingolipid Metabolism in NeurodegenerationKG

mechanism · 1,980 words · 291 hyp56 ana65 exp

⚙️ RNA Metabolism Dysfunction in Corticobasal SyndromeKG

mechanism · 1,903 words · 29 hyp46 ana119 exp

⚙️ Plasmalogen Metabolism in NeurodegenerationKG

mechanism · 1,852 words · 281 hyp57 ana55 exp

⚙️ Polyamine Metabolism Pathway in NeurodegenerationKG

mechanism · 1,767 words · 294 hyp58 ana60 exp

⚙️ RNA Metabolism Dysregulation in 4R-TauopathiesKG

mechanism · 1,707 words · 24 hyp45 ana119 exp

🏢 AD AMPK Activator and Energy Metabolism CompaniesKG

company · 1,699 words · 9 hyp5 ana2 exp

🔬 Amyloid-Beta Metabolism in Cortical NeuronsKG

cell · 1,655 words · 187 hyp62 ana24 exp

⚙️ PSP Oligodendrocyte Dysfunction and Iron MetabolismKG

mechanism · 1,599 words · 18 hyp39 ana22 exp

⚙️ Cerebral Cholesterol MetabolismKG

mechanism · 1,554 words · 32 hyp38 ana6 exp

⚙️ lipid-metabolism-pspKG

mechanism · 1,502 words · 36 hyp42 ana29 exp

🏥 cerebral-metabolism-perfusion-cbsKG

disease · 1,457 words · 1 hyp5 ana3 exp

⚙️ tRNA Metabolism in NeurodegenerationKG

mechanism · 1,449 words · 282 hyp57 ana54 exp

⚙️ RNA Metabolism Dysregulation PathwayKG

mechanism · 1,353 words · 39 hyp50 ana116 exp

🧫 Astrocyte Ferritin Iron Metabolism Dysfunction in Parkinson's DiseaseKG

experiment · 1,334 words · 115 hyp66 ana70 exp

⚙️ APOE Lipid Metabolism Pathway in Alzheimer's DiseaseKG

mechanism · 1,293 words · 85 hyp62 ana95 exp

⚙️ Cerebral Glucose Hypometabolism in NeurodegenerationKG

mechanism · 1,286 words · 284 hyp53 ana56 exp

⚙️ Glycolysis Metabolism in NeurodegenerationKG

mechanism · 1,244 words · 292 hyp59 ana54 exp

⚙️ Dopamine Metabolism PathwayKG

mechanism · 1,138 words · 127 hyp60 ana3 exp

⚙️ Glycosaminoglycan Metabolism PathwayKG

mechanism · 1,088 words · 25 hyp42 ana

⚙️ Astrocyte Iron Metabolism and Alpha-Synuclein Pathology in Parkinson's DiseaseKG

mechanism · 1,046 words · 137 hyp71 ana72 exp

🔬 Glucose Metabolism-Vulnerable NeuronsKG

cell · 600 words · 14 hyp16 ana6 exp

💡 APOE4 Lipid Metabolism OptimizationKG

idea · 578 words · 20 hyp25 ana38 exp

🏢 Dopamine Metabolism Enzymes Beyond COMTKG

company · 542 words · 110 hyp53 ana3 exp

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