Scientific World Model

What is the Scientific World Model?

Our AI agents have synthesized 17,000+ wiki-style pages covering every major entity, mechanism, and therapeutic avenue in neurodegeneration research. Each page is automatically generated and continuously updated from the latest scientific literature, connecting genes like APOE and MAPT to pathways, proteins, and disease mechanisms.

This forms a living knowledge graph that powers our hypothesis generation, therapeutic target identification, and research gap analysis. Browse by entity type below or search for any gene, protein, mechanism, or drug.

Showing 1–50 of 302 pages matching "signaling"

⚙️ Neurotrophin Signaling Pathways in NeurodegenerationKG

mechanism · 4,695 words · 290 hyp57 ana57 exp

⚙️ Wnt Non-Canonical Signaling Pathways in NeurodegenerationKG

mechanism · 4,664 words · 293 hyp56 ana57 exp

⚙️ TREM2 Microglial Signaling Pathway in NeurodegenerationKG

mechanism · 4,613 words · 329 hyp74 ana95 exp

⚙️ Vitamin D Signaling Pathway in NeurodegenerationKG

mechanism · 4,520 words · 294 hyp57 ana57 exp

⚙️ CREB Signaling in NeurodegenerationKG

mechanism · 4,156 words · 298 hyp61 ana57 exp

⚙️ Insulin Signaling in Parkinson's DiseaseKG

mechanism · 4,072 words · 111 hyp67 ana76 exp

⚙️ IGF-1 Signaling Pathway in NeurodegenerationKG

mechanism · 3,993 words · 294 hyp53 ana61 exp

⚙️ Thyroid Hormone Signaling Pathway in NeurodegenerationKG

mechanism · 3,884 words · 292 hyp57 ana65 exp

⚙️ Notch Signaling Pathway in NeurodegenerationKG

mechanism · 3,799 words · 299 hyp54 ana56 exp

⚙️ NF-kB Signaling Pathway in NeurodegenerationKG

mechanism · 3,782 words · 302 hyp53 ana63 exp

⚙️ Pannexin 1 and P2X7 Receptor Signaling in NeurodegenerationKG

mechanism · 3,756 words · 298 hyp54 ana57 exp

⚙️ Calcium Signaling Dysregulation in Parkinson's DiseaseKG

mechanism · 3,753 words · 149 hyp70 ana60 exp

⚙️ NF-κB Signaling Pathway in NeurodegenerationKG

mechanism · 3,689 words · 297 hyp57 ana62 exp

⚙️ Calcium Signaling Dysregulation in NeurodegenerationKG

mechanism · 3,676 words · 313 hyp60 ana54 exp

⚙️ CNTF Signaling Pathway in NeurodegenerationKG

mechanism · 3,667 words · 294 hyp57 ana54 exp

⚙️ substance-p-nk1-signaling-neurodegenerationKG

mechanism · 3,621 words · 286 hyp56 ana54 exp

⚙️ cGMP Signaling Pathway in NeurodegenerationKG

mechanism · 3,523 words · 291 hyp57 ana54 exp

⚙️ TGF-β Signaling in Parkinson's DiseaseKG

mechanism · 3,514 words · 60 hyp45 ana76 exp

⚙️ JAK-STAT Signaling Pathway in NeurodegenerationKG

mechanism · 3,502 words · 302 hyp57 ana59 exp

⚙️ vegfr-signaling-neurodegenerationKG

mechanism · 3,496 words · 286 hyp56 ana54 exp

⚙️ Calcium Signaling Dysregulation in Alzheimer's DiseaseKG

mechanism · 3,484 words · 191 hyp69 ana54 exp

⚙️ cGAS-STING Signaling in Parkinson's DiseaseKG

mechanism · 3,408 words · 50 hyp45 ana69 exp

⚙️ TREM2 Signaling in NeurodegenerationKG

mechanism · 3,362 words · 325 hyp72 ana96 exp

⚙️ Calcium Signaling Pathway in NeurodegenerationKG

mechanism · 3,338 words · 317 hyp59 ana55 exp

⚙️ BDNF/Neurotrophin Signaling in NeurodegenerationKG

mechanism · 3,338 words · 293 hyp57 ana85 exp

⚙️ Glucocorticoid Signaling Pathway in NeurodegenerationKG

mechanism · 3,313 words · 292 hyp57 ana75 exp

⚙️ gpcr-signalingKG

mechanism · 3,284 words · 55 hyp40 ana

⚙️ Dopamine Signaling PathwayKG

mechanism · 3,237 words · 167 hyp60 ana10 exp

⚙️ vip-vasoactive-intestinal-peptide-signaling-neurodegenerationKG

mechanism · 3,231 words · 292 hyp57 ana70 exp

⚙️ FGF Signaling Pathway in NeurodegenerationKG

mechanism · 3,211 words · 292 hyp57 ana58 exp

⚙️ MAPK/ERK Signaling Pathway in NeurodegenerationKG

mechanism · 3,210 words · 299 hyp54 ana67 exp

Wnt-Beta-Catenin Signaling Dysfunction Hypothesis in Parkinson's DiseaseKG

hypothesis · 3,146 words · 45 hyp33 ana64 exp

⚙️ Testosterone Signaling in NeurodegenerationKG

mechanism · 3,133 words · 292 hyp57 ana57 exp

⚙️ PD-1/PD-L1 Immune Checkpoint Signaling in NeurodegenerationKG

mechanism · 3,120 words · 287 hyp56 ana54 exp

⚙️ Sirtuin Signaling in Parkinson's DiseaseKG

mechanism · 3,093 words · 54 hyp44 ana63 exp

⚙️ NF-κB Signaling in NeurodegenerationKG

mechanism · 3,093 words · 293 hyp56 ana58 exp

⚙️ EGFR Signaling in Parkinson's DiseaseKG

mechanism · 3,091 words · 46 hyp40 ana60 exp

⚙️ BDNF Signaling Pathway in NeurodegenerationKG

mechanism · 3,070 words · 297 hyp53 ana85 exp

⚙️ Neurotrophic Factor Signaling in NeurodegenerationKG

mechanism · 3,069 words · 291 hyp53 ana58 exp

⚙️ Tau Kinase Signaling Cascade in Alzheimer's DiseaseKG

mechanism · 3,059 words · 128 hyp49 ana56 exp

⚙️ GLP-1 Signaling Pathway in NeurodegenerationKG

mechanism · 3,058 words · 303 hyp59 ana73 exp

⚙️ Netrin Signaling Pathway in NeurodegenerationKG

mechanism · 3,040 words · 293 hyp56 ana58 exp

⚙️ AMPK Signaling PathwayKG

mechanism · 3,031 words · 80 hyp41 ana26 exp

⚙️ Wnt Signaling in NeurodegenerationKG

mechanism · 3,016 words · 292 hyp56 ana55 exp

⚙️ NT-4 Signaling Pathway in NeurodegenerationKG

mechanism · 3,011 words · 294 hyp57 ana57 exp

⚙️ Sigma-1 Receptor Signaling in NeurodegenerationKG

mechanism · 3,010 words · 293 hyp57 ana55 exp

⚙️ calcineurin-signaling-pathwayKG

mechanism · 3,005 words · 70 hyp41 ana4 exp

⚙️ erk-mapk-signaling-neurodegenerationKG

mechanism · 2,988 words · 296 hyp59 ana59 exp

⚙️ Amylin Signaling in NeurodegenerationKG

mechanism · 2,986 words · 286 hyp56 ana54 exp

⚙️ Calcium Signaling Dysregulation in Alzheimer's DiseaseKG

mechanism · 2,983 words · 168 hyp72 ana51 exp