Scientific World Model

The world's most comprehensive mechanistic knowledge base for neurodegenerative diseases.

17,471 pages — genes, proteins, mechanisms, therapeutics, and more

What is the Scientific World Model?

Our AI agents have synthesized 17,000+ wiki-style pages covering every major entity, mechanism, and therapeutic avenue in neurodegeneration research. Each page is automatically generated and continuously updated from the latest scientific literature, connecting genes like APOE and MAPT to pathways, proteins, and disease mechanisms.

This forms a living knowledge graph that powers our hypothesis generation, therapeutic target identification, and research gap analysis. Browse by entity type below or search for any gene, protein, mechanism, or drug.

All (17,471)🧬 gene (3,869)🔬 cell (3,397)🔬 protein (3,107)⚙️ mechanism (1,789)💊 therapeutic (1,028)🏢 company (643)🏥 disease (496)🧪 clinical (392)🏛️ institution (308)👤 researcher (214)💡 idea (200)↪️ redirect (185)📊 biomarker (182)🧫 experiment (161) general (151)🔧 technology (151) ai_tool (141) entity (113)
Showing 1–15 of 15 pages matching "synapse"

⚙️ Complement-Mediated Synapse LossKG

mechanism · 3,185 words · 199 hyp62 ana3 exp

⚙️ Synapse Elimination in NeurodegenerationKG

mechanism · 3,142 words · 302 hyp60 ana57 exp

⚙️ Tripartite SynapseKG

mechanism · 2,531 words · 23 hyp37 ana5 exp

💡 Synapse-Resilience Circuit: BDNF Therapy + Sleep-Glymphatic EntrainmentKG

idea · 2,529 words · 114 hyp59 ana23 exp

💡 Neurogranin-Guided Synapse Rescue TherapyKG

idea · 2,006 words · 51 hyp35 ana16 exp

🔬 SAP102 Protein — Synapse-Associated Protein 102KG

protein · 1,964 words · 5 hyp10 ana

⚙️ CR3-Dependent Microglial Synapse Elimination in Parkinson's DiseaseKG

mechanism · 1,931 words · 46 hyp51 ana64 exp

🔬 Climbing Fiber SynapsesKG

cell · 1,553 words · 5 hyp5 ana1 exp

💡 Integrin-Synapse Stabilization TherapyKG

idea · 1,266 words · 28 hyp18 ana1 exp

🔬 Synapse-Associated Protein 97KG

protein · 1,135 words · 6 hyp11 ana

🔬 Parallel Fiber SynapsesKG

cell · 964 words · 4 hyp5 ana1 exp

payload-integrin-synapse-adhesion-modulationKG

general · 950 words · 20 hyp13 ana

🔬 Microglia in Synapse PruningKG

cell · 691 words · 188 hyp68 ana18 exp

↪️ Locus Coeruleus Alpha Neurons

redirect · 658 words · 7 hyp15 ana1 exp

🧬 SAP97 - Synapse-Associated Protein 97KG

gene · 642 words · 7 hyp11 ana

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