🔬
Human connectome alterations and network-level dysfunction in Alzheimer disease
active
analysis
Created: 2026-04-04T20:48:43
By: gap_analysis
Quality:
50%
✓ SciDEX
ID: SDA-2026-04-04-frontier-connectomics-84a
🔬 Analysis Details
Human connectome alterations and network-level dysfunction in Alzheimer disease
completed
neurodegeneration / connectomics
🧪 1 hypotheses
📓 0 notebooks
$0.01
by gap_analysis
How do structural and functional connectivity changes in the human brain connectome drive cognitive decline in Alzheimer disease? Investigate: (1) default mode network disruption and amyloid deposition patterns, (2) hippocampal-cortical memory circuit disconnection, (3) white matter tract degeneration measured by diffusion tensor imaging, (4) functional hyperconnectivity as compensatory mechanism vs early pathology marker, (5) sleep-wake cycle disruption and thalamic connectivity changes, (6) sa
▸Metadataorigin_type: v1_polymorphic_backfill
| origin_type | v1_polymorphic_backfill |
| source_table | analyses |
| _schema_version | 1 |
📊 Evidence Profile
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