gene

CHD1L

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about CHD1L: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

3Connections

0Hypotheses

0Analyses

3Outgoing

0Incoming

0Experiments

0Debates

Summary

Page for CHD1L Gene

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🧬 Gene Info

Gene Symbol	CHD1L
Full Name	Chromodomain Helicase DNA-Binding Protein 1-Like
Chromosome	1q21.1
Protein Type	SNF2 family chromatin remodeler
Function	CHD1L belongs to the SNF2 family of ATP-dependent chromatin remodelers.
Primary Expression	neurons and glial cells, with particular enrichment in regions associated with learning and memory
Molecular Weight	~110 kDa
Pathways	epigenetic regulation
GeneCards	CHD1L
Human Protein Atlas	CHD1L
Location	Chromosome 1q21.1
Protein Class	SNF2 family chromatin remodeler
Associated Diseases	neurodegeneration
KG Connections	3 knowledge graph edges
Databases	GeneCards UniProt NCBI Gene HPA STRING

Wiki Pages (4)

Knowledge base pages for this entity

Canonical Page

Pathway Diagram

graph TD
    CHD1L["CHD1L"]
    style CHD1L fill:#1a237e,stroke:#4fc3f7,stroke-width:3px,color:#fff
    DNMT3A(["DNMT3A"])
    TET2["TET2"]
    epigenetic_regulation["epigenetic regulation"]
    neurodegeneration["neurodegeneration"]

    CHD1L -->|"regulates"| DNMT3A
    CHD1L -->|"regulates"| TET2
    CHD1L -->|"participates_in"| epigenetic_regulation
    CHD1L -->|"implicated_in"| neurodegeneration

    classDef gene fill:#1a3a2a,stroke:#4caf50,color:#e0e0e0
    classDef protein fill:#1a2a3a,stroke:#4fc3f7,color:#e0e0e0
    classDef disease fill:#3a1a1a,stroke:#ef5350,color:#e0e0e0
    classDef pathway fill:#2a1a3a,stroke:#ce93d8,color:#e0e0e0
    classDef mechanism fill:#2a2a1a,stroke:#ffd54f,color:#e0e0e0
    classDef drug fill:#1a2a2a,stroke:#80cbc4,color:#e0e0e0
    class DNMT3A protein
    class TET2 gene
    class epigenetic_regulation protein
    class neurodegeneration disease

Outgoing (3)

Target	Relation	Type	Str
DNMT3A	regulates	gene	0.55
TET2	regulates	gene	0.55
epigenetic regulation	participates_in	pathway	0.55

Incoming (0)

Source	Relation	Type	Str
No incoming edges

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity